Pathogenesis of Sjögren's syndrome and therapeutic consequences.

abstract：:In this review, four areas are discussed: fluoroquinolone-induced tendinitis, volar flexor tenosynovitis (trigger finger), Achilles tendon lesions, and occupational medicine issues. The relationship of fluoroquinolone treatment to musculoskeletal lesions, especially Achilles tendinitis and tear, is most intriguing. Th...

journal_title：Current opinion in rheumatology

authors： Biundo JJ Jr,Mipro RC Jr,Fahey P

更新日期：1997-03-01 00:00:00

abstract：:Organ transplantation offers new life to patients who suffer from incurable disease. The problem of rejection of the transplanted organ has been overcome with the use of potent immunosuppressive drugs. These drugs, although they allow graft tolerance and graft survival, also are associated with complications such as o...

journal_title：Current opinion in rheumatology

authors： Epstein S,Shane E,Bilezikian JP

更新日期：1995-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Myositis, or idiopathic inflammatory myopathy, is an overarching concept that includes dermatomyositis, polymyositis, immune-mediated necrotizing myopathy and the antisynthetase syndrome. Glucocorticoids are still considered the mainstay of treatment of myositis but some patients require add-on immuno...

journal_title：Current opinion in rheumatology

authors： Pipitone N,Salvarani C

更新日期：2020-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Takayasu arteritis remains a therapeutic challenge. In spite of current treatments, progression of vascular lesions is observed frequently. The purpose of this article is to describe advances in therapeutic strategies for Takayasu arteritis. RECENT FINDINGS:Immunosuppressive agents including methotre...

journal_title：Current opinion in rheumatology

authors： Liang P,Hoffman GS

更新日期：2005-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the emergence, clinical features, pathogenesis, and treatment of acute chikungunya (CHIK) fever and chronic CHIK arthritis. RECENT FINDINGS:Since 2004, CHIK, an arboviral infection, has spread throughout the world, infecting millions of people. The illness occurs in two phases: an acute vir...

journal_title：Current opinion in rheumatology

authors： Sutaria RB,Amaral JK,Schoen RT

更新日期：2018-05-01 00:00:00

abstract：:Shoulder injuries are common in the athletic population. Injuries can be a result of repetitive overhead use or from direct trauma. Common injury sites include the rotator cuff, glenohumeral joint, acromioclavicular joint, biceps tendon, scapulothoracic articulation, and sternoclavicular joint. The identification, phy...

journal_title：Current opinion in rheumatology

authors： Ong BC,Sekiya JK,Rodosky MW

更新日期：2002-03-01 00:00:00

abstract：:The recent literature pertaining to tumors of articular structures and bone is reviewed. In pigmented villonodular synovitis, the bone resorptive cell is a macrophage polykaryon rather than an osteoclast. Complete arthroscopic synovectomy was successful in most diffuse articular forms of the disease. The early synovia...

journal_title：Current opinion in rheumatology

authors： Abraham JH 3rd,Canoso JJ

更新日期：1993-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this study was to evaluate the relationship between infection with SARS-CoV-2 and autoimmunity. RECENT FINDINGS:Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome (SARS) associated coronavirus 2 (SARS-CoV-2). Although most of the infect...

journal_title：Current opinion in rheumatology

authors： Liu Y,Sawalha AH,Lu Q

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Current trends in the management of Behçet's syndrome will be reviewed in this article. RECENT FINDINGS:Biologic agents have gained increasing importance over the years in the management of Behçet's syndrome. Long-term results of observational studies have shown that anti-tumor necrosis factor agents...

journal_title：Current opinion in rheumatology

authors： Ozguler Y,Hatemi G

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with rheumatoid arthritis and other inflammatory arthritides treated with tumor necrosis factor inhibitors frequently undergo orthopedic procedures. These patients may be at risk for serious postoperative infections as antitumor necrosis factor agents may be associated with impaired immunity ...

journal_title：Current opinion in rheumatology

authors： Pappas DA,Giles JT

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Incorporation of the patients' perspective in clinical research is critical to ensure that outcomes measured reflect those, which matter most to patients. This review summarizes recent efforts to include the patients' perspective in the development of outcome measures and the importance of encouraging...

journal_title：Current opinion in rheumatology

authors： Hsiao B,Fraenkel L

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Blau syndrome is a monogenic disease resulting from mutations in nucleotide oligomerization domain 2 (NOD2) and is phenotypically characterized by granulomatous polyarthritis and uveitis. Not only there has been significant progress in disease characterization but also the biological pathways associat...

journal_title：Current opinion in rheumatology

authors： Rose CD,Martin TM,Wouters CH

更新日期：2011-09-01 00:00:00

abstract：:Eosinophilic infiltration into skeletal muscle, although rare, has been described in a diverse group of conditions. It most commonly occurs in parasitic infection as focal eosinophilic myositis but can be a feature of systemic hypereosinophilic conditions such as eosinophilia-myalgia syndrome and idiopathic hypereosin...

journal_title：Current opinion in rheumatology

authors： Pickering MC,Walport MJ

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The identification of the genetic variants that mediate the risk for susceptibility and severity of rheumatoid arthritis will allow the development of new drug targets and also increase the ability to predict disease course. Technical and methodologic progress has fueled the advances in this field. R...

journal_title：Current opinion in rheumatology

authors： van der Helm-van Mil AH,Wesoly JZ,Huizinga TW

更新日期：2005-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent interest in gout has led to development of new drugs for acute gout and long-term urate-lowering, as well as interest in improving the use of older drugs. The patients' comorbidities and concomitant medications may contribute to the risk of adverse drug reactions with anti-gout therapies. This ...

journal_title：Current opinion in rheumatology

authors： Stamp LK

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Arthritogenic alphaviruses are globally distributed mosquito-borne RNA viruses causing epidemics of polyarthritis/arthralgia, with disease emerging or reemerging and increasingly being reported in travelers. This article summarizes the current knowledge of these diseases, focusing on recent developmen...

journal_title：Current opinion in rheumatology

authors： Suhrbier A,La Linn M

更新日期：2004-07-01 00:00:00

abstract：:In this review, we address current concepts and recent experimental results that relate to heterogeneity in the physiologic, biochemical, and morphologic properties of mammalian skeletal muscle fibers. Recent data reinforce some of these current concepts while questioning others. The biochemical bases of the concepts ...

journal_title：Current opinion in rheumatology

authors： Talmadge RJ,Roy RR,Edgerton VR

更新日期：1993-11-01 00:00:00

abstract：:The last few years have brought a resurgence in interest in managing systemic sclerosis. In the past year, there have been reports of small series of patients and several well-designed, double-blind, controlled trials. Treatment has been directed at a variety of potential pathogenic mechanisms. Stanazol, iloprost, pla...

journal_title：Current opinion in rheumatology

authors： Steen V

更新日期：1991-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims at covering the role of muscle MRI in supporting the diagnosis of myositis, in aiding to differentiate it from other muscle disorders, and in monitoring myositis patients over time by assessing response to treatment and by discriminating between muscle inflammation and chronic damage....

journal_title：Current opinion in rheumatology

authors： Pipitone N

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Significant advances in the treatment of antineutrophil cytoplasmic antibody-associated vasculitis have been made in the past 10 years. This review aims to detail advances in treatment aimed at induction of remission. RECENT FINDINGS:Cyclophosphamide-based regimes remain the standard of care, at leas...

journal_title：Current opinion in rheumatology

authors： Harper L

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF THIS REVIEW:Gene expression profiling is emerging as a promising methodology in pediatric rheumatology research. There is considerable interest in using this technology as the basis for diagnostic assays. This review will summarize the new knowledge. RECENT FINDINGS:Most gene expression studies of children ...

journal_title：Current opinion in rheumatology

authors： Jarvis JN

更新日期：2005-09-01 00:00:00

abstract：:In 1990, there were signs of a renewed interest in clinical studies about several aspects of osteoarthritis. The work-up of classic data and the use of new information from epidemiologic surveys as well as careful radiographic monitoring of selected groups of patients have brought us broader views on the general cours...

journal_title：Current opinion in rheumatology

authors： Peyron JG

更新日期：1991-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary fibrosis is a devastating disease that affects millions of people worldwide. Among the most common forms of lung fibrosis are idiopathic pulmonary fibrosis (IPF) and scleroderma-related interstitial lung disease (SSc-ILD). Despite a wealth of literature regarding each of these diseases, stud...

journal_title：Current opinion in rheumatology

authors： Murray LA,Rubinowitz A,Herzog EL

更新日期：2012-11-01 00:00:00

abstract：:The immune defense against extracellular pathogens is largely dependent on antibody production. Class switch recombination and somatic hypermutation shape the secondary antibody repertoire in peripheral lymphoid tissue. In the past few years, a series of primary immune deficiencies characterized by defects in these pr...

journal_title：Current opinion in rheumatology

authors： Gulino AV,Notarangelo LD

更新日期：2003-07-01 00:00:00

abstract：:Angiitis of the central nervous system (CNS) remains a poorly understood and clinically challenging form of vascular inflammatory disease. Primary angiitis of the CNS (PACNS) has been viewed as a relentless and uniformly fatal disorder if untreated. In addition, recent trends have demonstrated an increasing reliance o...

journal_title：Current opinion in rheumatology

authors： Calabrese LH,Duna GF

更新日期：1995-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Advances in understanding the genetic and molecular basis of innate immune system activation and function have supported the hypothesis that type I interferons (IFN-I), the essential mediators of antiviral host defense, are central contributors to the pathogenesis of systemic lupus erythematosus (SLE)...

journal_title：Current opinion in rheumatology

authors： Crow MK

更新日期：2014-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Across the world, osteoarthritis is the most commonly occurring musculoskeletal disease of the elderly, affecting more than 25% of the population older than 60 years of age. By far the single greatest risk factor for the development of osteoarthritis is age, but a mechanism to explain this relation ha...

journal_title：Current opinion in rheumatology

authors： Verzijl N,Bank RA,TeKoppele JM,DeGroot J

更新日期：2003-09-01 00:00:00

abstract：:Osteoarthritis is the most common form of arthritis in adults and its incidence increases with age. More than 50% of people aged 65 and older have radiographic changes of knee osteoarthritis. Calcium crystals, including calcium pyrophosphate dihydrate and basic calcium phosphate crystals, are also common in the elderl...

journal_title：Current opinion in rheumatology

authors： Jaovisidha K,Rosenthal AK

更新日期：2002-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent evidence for infection rates in patients with systemic vasculitides, the role of specific infectious agents in the pathogenesis of vasculitis and recent breakthroughs in the treatment of virus-associated vasculitides. RECENT FINDINGS:In well designed recent studies, infections were f...

journal_title：Current opinion in rheumatology

authors： Thomas K,Vassilopoulos D

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Regeneration of damaged articular cartilage remains one of the most challenging problems in orthopedic surgery. Distinct surgical procedures were developed for the repair of focal cartilage defects and this review will focus on recent aspects of cell-based healing approaches that aim to achieve restor...

journal_title：Current opinion in rheumatology

authors： Richter W

更新日期：2007-09-01 00:00:00