Abstract：
OBJECTIVE:Childhood scleroderma encompasses a rare, poorly understood spectrum of conditions. Our aim was to ascertain the incidence of childhood scleroderma in its different forms in the UK and Ireland, and to describe the age, sex, and ethnicity of the cases. METHODS:The members of 5 specialist medical associations including pediatricians, dermatologists, and rheumatologists were asked to report all cases of abnormal skin thickening suspected to be localized (including linear) scleroderma or systemic sclerosis (SSc) in children <16 years of age first seen between July 2005 and July 2007. RESULTS:We received notification of 185 potential cases, and 94 valid cases were confirmed: 87 (93%) with localized scleroderma and 7 (7%) with SSc. This gave an incidence rate per million children per year of 3.4 (95% confidence interval [95% CI] 2.7-4.1) for localized scleroderma, including an incidence rate of 2.5 (95% CI 1.8-3.1) for linear scleroderma, and 0.27 (95% CI 0.1-0.5) for SSc. Of the 87 localized cases, 62 (71%) had linear disease. Of localized disease cases, 55 (63%) were female, 71 (82%) were classified as white British, and the patients' mean age when first seen in secondary care was 10.4 years. Of the 7 SSc cases, all were female, 6 (86%) were white British, and the mean age when first seen was 12.1 years. The median delay between onset and being first seen was 13.1 months for localized scleroderma and 7.2 months for SSc. CONCLUSION:These data provide additional estimates of the incidence of this rare disorder and its subforms.
journal_name
Arthritis Care Res (Hoboken)journal_title
Arthritis care & researchauthors
Herrick AL,Ennis H,Bhushan M,Silman AJ,Baildam EMdoi
10.1002/acr.20070subject
Has Abstractpub_date
2010-02-01 00:00:00pages
213-8issue
2eissn
2151-464Xissn
2151-4658journal_volume
62pub_type
杂志文章abstract：OBJECTIVE:To examine temporal trends in mortality rates in a large nationwide cohort of patients with end-stage renal disease (ESRD) due to granulomatosis with polyangiitis (Wegener's) (GPA-ESRD). METHODS:We identified cases of GPA-ESRD reported in the US Renal Data System between 1995 and 2014, using coding by nephro...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.23521
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:To determine the extent to which demographic and geographic disparities exist in the use of post-acute rehabilitation care (PARC) for joint replacement. METHODS:We conducted a cross-sectional analysis of 2 years (2005 and 2006) of population-based hospital discharge data from 392 hospitals in 4 states (Arizo...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.20477
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:This double-blind randomized controlled trial aimed to test the efficacy of self-administered acupressure for pain and physical function improvement for older adults with knee osteoarthritis (OA). METHODS:Participants were community-dwelling adults with symptomatic knee OA (n = 150, mean age 73 years), rando...
journal_title：Arthritis care & research
pub_type： 杂志文章,随机对照试验
doi：10.1002/acr.23262
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:Joint replacement surgery is a proxy of severe joint damage in rheumatoid arthritis (RA). The aim of this study was to assess the impact of the introduction of biologic disease-modifying antirheumatic drugs (bDMARDs) on the incidence rate (IR) of upper limb joint replacements among newly diagnosed RA patients...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.23835
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare the feasibility and effectiveness of neuromuscular electrical stimulation (NMES) with that of high-intensity volitional resistance training for improving muscle structure and function and physical function in patients with rheumatoid arthritis (RA). We also compared pre-in...
journal_title：Arthritis care & research
pub_type： 杂志文章,随机对照试验
doi：10.1002/acr.23602
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:To compare the time-varying behavior of maximum toe-out angle, lateral trunk lean (over the stance leg), and pelvic obliquity (rise and drop on the swing leg) during prolonged walking in participants with and without medial compartment knee osteoarthritis (OA), and to explore correlations between these gait c...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.21584
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE:To determine if low disease activity state (LDAS)/remission predicts a better health-related quality of life (HRQoL). METHODS:Patients with systemic lupus erythematosus from a single center and having completed at least 2 visits were included. Visits were performed every 6 months. HRQoL was measured with the...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.24009
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:To determine if a pharmacist-initiated multidisciplinary strategy provides value for money compared to usual care in participants with previously undiagnosed knee osteoarthritis. METHODS:Pharmacies were randomly allocated to provide either 1) usual care and a pamphlet or 2) intervention care, which consisted...
journal_title：Arthritis care & research
pub_type： 杂志文章,随机对照试验
doi：10.1002/acr.22232
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:Knowledge about systemic lupus erythematosus (SLE) outcomes among US Asians is lacking. We examined SLE disease activity, severity, and damage among Asians of primarily Chinese and Filipino descent in a multiethnic cohort. METHODS:California Lupus Epidemiology Study (CLUES, n=328) data were analyzed. Data we...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.24544
更新日期：2020-12-18 00:00:00
abstract：:We read with great interest the editorial on foot osteoarthritis (OA) by Golightly and Gates (1). Foot OA is prevalent but neglected compared with other commonly affected sites such as the knee and hand (2), hence such a high-profile statement of need for foot OA is long overdue. ...
journal_title：Arthritis care & research
pub_type： 信件
doi：10.1002/acr.24380
更新日期：2020-07-23 00:00:00
abstract：OBJECTIVE:Clinically amyopathic dermatomyositis (CADM) is a subset of dermatomyositis (DM) presenting with the characteristic rash of DM without objective muscle weakness. Asian studies report that anti-melanoma differentiation-associated gene 5 (anti-MDA-5) autoantibody in CADM is associated with interstitial lung dis...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.22728
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:A lack of agreement between clinician and patient priorities can impact the clinician-patient relationship, treatment concordance, and potential health outcomes. Studies have suggested that patients with osteoarthritis (OA) may prioritize comorbidities over their OA, but as yet no explicit systematic explorat...
journal_title：Arthritis care & research
pub_type： 杂志文章,多中心研究
doi：10.1002/acr.21897
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:To examine the association between socioeconomic status (SES) and delay to a pediatric rheumatology clinic, disease severity, and illness perception in patients with juvenile idiopathic arthritis in England. METHODS:Using the Index of Multiple Deprivation, 923 consecutive children from the Childhood Arthriti...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.22466
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:By 2030, the number of permanently homebound individuals in the US will increase by 50% to reach 2 million. However, no medicine subspecialty consult services exist for this rising subset of the population. This pilot program establishes a rheumatology consult service for the Mount Sinai Visiting Doctors, the...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.20539
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:In early rheumatoid arthritis (RA), treating to a target is more effective than routine care (RC). Our aim was to determine if treating to a target has better outcomes than RC in established active RA. METHODS:We used a real-world, 18-month cluster-randomized trial in established active RA patients treated w...
journal_title：Arthritis care & research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1002/acr.22010
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To determine whether the effect of the Strengthening and Stretching for Rheumatoid Arthritis of the Hand (SARAH) exercise program on hand function was mediated by changes in the proposed active ingredients: strength, dexterity, and/or range of motion. METHODS:The SARAH intervention included exercises hypothe...
journal_title：Arthritis care & research
pub_type： 杂志文章,随机对照试验
doi：10.1002/acr.23093
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:Reactivation of Mycobacterium tuberculosis infection is a major complication in patients treated with anti-tumor necrosis factor (anti-TNF) agents. We report on the 5 cases of active tuberculosis (TB) that developed in the Golimumab Phase III Program (3 with rheumatoid arthritis, 1 with psoriatic arthritis, a...
journal_title：Arthritis care & research
pub_type： 杂志文章,随机对照试验
doi：10.1002/acr.21788
更新日期：2013-02-01 00:00:00
abstract：OBJECTIVE:The RhoA/Rho kinase pathway plays a pivotal role in cold-induced vasoconstriction, vascular smooth muscle cells function, and vascular homeostasis. This study evaluates the efficacy of fasudil, a RhoA/Rho kinase inhibitor, to reverse cold-induced vasospasm in patients with Raynaud's phenomenon (RP) secondary ...
journal_title：Arthritis care & research
pub_type： 杂志文章,随机对照试验
doi：10.1002/acr.21622
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:To evaluate heterogeneity of treatment effects (HTE) in a trial of exercise-based interventions for knee osteoarthritis (OA). METHODS:Participants (n=350) were randomized to standard physical therapy (PT; n=140), Internet-Based Exercise Training (IBET; n=142), or wait list control (WL; n=68). We applied QUal...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.24564
更新日期：2021-01-18 00:00:00
abstract：BACKGROUND:Cognitive function may change over time in patients with SLE, and cognitive function trajectories have not well been studied. We aim to: 1) identify cognitive function trajectories in SLE and describe it with depressive symptoms trajectories and 2) identify baseline factors associated with class membership i...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.24349
更新日期：2020-06-11 00:00:00
abstract：OBJECTIVE:To investigate differences in EMG muscle activity and scapular kinematics during elevation in the scapular plane between healthy controls, participants with multidirectional shoulder laxity (MDL), and patients with multidirectional shoulder instability (MDI) who are diagnosed with hypermobile Ehlers-Danlos sy...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.24525
更新日期：2020-11-30 00:00:00
abstract：OBJECTIVE:To determine the impact of stopping tumor necrosis factor inhibitor (TNFi) treatment on patient-reported outcomes (PROs) of physical and mental health status, health utility, pain, disability, and fatigue in patients with established rheumatoid arthritis (RA). METHODS:In the pragmatic, 12-month POET trial, 8...
journal_title：Arthritis care & research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1002/acr.23315
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy, tolerability, and safety of cannabinoids (phyto- and syntheto-) in the management of rheumatic diseases. METHODS:Multiple databases, including Medline, Embase, and CENTRAL, were searched. Randomized controlled trials with outcomes of pain, sleep, quality of life, tolerability (dropout...
journal_title：Arthritis care & research
pub_type： 杂志文章,评审
doi：10.1002/acr.22727
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the validity of different spondyloarthritis (SpA) features included in the Berlin diagnostic algorithm and the Assessment of SpondyloArthritis international Society (ASAS) classification criteria in an early SpA cohort. METHODS:This was a longitudinal multicenter study including patients from the...
journal_title：Arthritis care & research
pub_type： 杂志文章,多中心研究
doi：10.1002/acr.23017
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:Although several individual nutrients/foods are associated with uric acid status, the association of overall diet quality with hyperuricemia remains unclear. We thus examined the association between adherence to the dietary approaches to stop hypertension (DASH) diet and odds of having hyperuricemia in a Chin...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.24150
更新日期：2020-01-21 00:00:00
abstract：OBJECTIVE:To determine time trends in the incidence and survival of polymyalgia rheumatica (PMR) over a 15-year period in Olmsted County, Minnesota, and to examine trends in incidence of PMR in the population by comparing this time period to a previous incidence cohort from the same population base. METHODS:All cases ...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.23132
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:To describe the experiences and strategies of employees with arthritis to maintain employment, and to use this information to build a conceptual model. METHODS:We conducted a systematic review of qualitative studies that examined the work experiences of employees with arthritis. Published studies on arthriti...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.23528
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:To determine whether the presence of magnetic resonance imaging (MRI) osteoarthritis (OA) features in the patellofemoral or tibiofemoral joint (i.e., bone marrow lesions, cartilage lesions, and osteophytes) and/or functional impairments, 1 year following anterior cruciate ligament reconstruction (ACLR), can p...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.22761
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:To determine the influence of socioeconomic factors on disease activity in a Latin American (LA) early rheumatoid arthritis (RA) multinational inception cohort at baseline. METHODS:Clinical evaluation, ethnicity, socioeconomic status (SES), 4-variable Disease Activity Score in 28 joints using the erythrocyte...
journal_title：Arthritis care & research
pub_type： 杂志文章,多中心研究
doi：10.1002/acr.21680
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVES:Fibromyalgia (FM) is a chronic painful condition partly due to alterations in pain modulation by the central nervous system. Multicomponent therapy (MT) and repetitive transcranial magnetic stimulation (rTMS) had both been reported as pain modulators in FM patients. The aim of this study was to compare the e...
journal_title：Arthritis care & research
pub_type： 杂志文章
doi：10.1002/acr.24118
更新日期：2019-11-30 00:00:00
