Viability of loose body fragments in osteochondritis dissecans of the knee. A series of cases.


:The purpose of this study was to determine if the cartilage from loose osteochondral fragments remains viable. Five patients with OCD of the knee who had undergone surgical treatment (arthroscopic reduction and internal fixation of the loose body) were included. The average age of patients was 13 years (range 10-14 years). Cartilage samples were obtained from the loose body fragments before reattachment was performed (study group) and from the healthy native cartilage (intercondyle area, control group) from each of the five patients. Tissue viability was assessed using live-dead assay in both groups. All five loose osteochondral fragments showed similar viability to the healthy native cartilage group, with 88% cell viability (95% CI 50-100) in loose body fragments versus 92% viability (95% CI 50-100) from healthy cartilage. This study showed that cartilage from detached OCD fragments remains viable before reattachment is performed.


Int Orthop


Pascual-Garrido C,Tanoira I,Muscolo DL,Ayerza MA,Makino A




Has Abstract


2010-08-01 00:00:00












  • Operative or conservative treatment in patients with Rockwood type III acromioclavicular dislocation: a systematic review and update of current literature.

    abstract:PURPOSE:Despite previous studies the management of Rockwood type III acromioclavicular (AC) dislocations remains controversial and the debate continues about whether patients with Rockwood type III AC injuries should be treated conservatively or operatively. In this study, we will review the current literature and pres...

    journal_title:International orthopaedics

    pub_type: 杂志文章,评审


    authors: Korsten K,Gunning AC,Leenen LP

    更新日期:2014-04-01 00:00:00

  • Surgical treatment of chronic complete acromioclavicular dislocation.

    abstract::We treated surgically 14 patients with symptomatic complete dislocation of the acromioclavicular joint. The surgical procedure included reconstruction of the coracoclavicular ligament using the coracoacromial ligament as substitute, reconstruction of the acromioclavicular ligament, and imbrications of the deltotrapezi...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Adam FF,Farouk O

    更新日期:2004-04-01 00:00:00

  • Lengthening osteotomy of the fibula to correct a widened mortice of the ankle after fracture.

    abstract::The subtle diagnosis of widening of the mortice requires special radiographs which also make possible the recognition and extent of shortening of the fibula. With the help of a special compression/distraction device, a lengthening osteotomy can be carried out more easily then by conventional means. a reconstructive le...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Weber BG

    更新日期:1981-01-01 00:00:00

  • Evaluation of biomarkers of joint damage in patients subjected to arthroscopy.

    abstract:AIMS:Recently, the determination of biochemical markers has been intensely explored to better understand the mechanisms underlying knee OA. In this study, we aimed to explore the expression pattern of five biochemical markers in patients with knee OA. METHODS:After IRB approval and signed informed consent, 26 patients...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Izaguirre A,González-Gutiérrez G,Galindo-López SE,Arenas-Serna G,Rodríguez A,Flores-Torrero E,Franco Y Bourland RE,Ballinas-Verdugo MA,Sánchez-Muñoz F

    更新日期:2020-10-01 00:00:00

  • Posterolateral clamp placement on the pelvic brim provides optimal reduction of transtectal acetabular fractures fixed through the anterior intrapelvic approach.

    abstract:PURPOSE:To determine the optimal position of reduction clamps applied to reduce transtectal transverse acetabular fractures approached through the anterior intrapelvic route. METHODS:Transtectal transverse fractures were created in sawbone hemipelvis models. Fractures were reduced and held with a large pointed reducti...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Crump EK,Hwang J,Vintimilla DR,Parry JA,Maher M,Salameh M,Mauffrey C

    更新日期:2020-02-01 00:00:00

  • Tendon injuries induced by exercise and anabolic steroids in experimental mice.

    abstract::The purpose of this study was to examine the effect of anabolic steroid hormones and exercise training on skeletal tendons. Female mice were exercised for 1 and 10 weeks in an endurance running programme on a treadmill. The altered ultrastructure of tendons caused by simultaneously administered anabolic steroid hormon...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Michna H

    更新日期:1987-01-01 00:00:00

  • Pathological fracture of a lumbar vertebra caused by rheumatoid arthritis--a case report.

    abstract::We describe a case of rheumatoid arthritis (RA) with collapse of the L3 lumbar vertebra for which surgery was performed. The pathogenesis of lumbar lesions affected by RA is discussed and the literature reviewed. ...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Nakase T,Fujiwara K,Kohno J,Owaki H,Tomita T,Yonenobu K,Ochi T

    更新日期:1998-01-01 00:00:00

  • Use of intramedullary fibular strut graft: a novel adjunct to plating in the treatment of osteoporotic humeral shaft nonunion.

    abstract::Humeral shaft fractures respond well to conservative treatment and unite without much problem. Since it is uncommon, there is not much discussion regarding the management of nonunion in the literature, and hence this is a challenge to the treating orthopaedic surgeon. Osteoporosis of the fractured bone and stiffness o...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Vidyadhara S,Vamsi K,Rao SK,Gnanadoss JJ,Pandian S

    更新日期:2009-08-01 00:00:00

  • Rupture of the ankle ligaments.

    abstract::A prospective randomised trial of treatment of ruptured ankle ligaments was carried out at our institute. Two hundred patients were randomly assigned to 4 treatment groups. The results at 1 and 2 years after injury showed that functional treatment with a newly designed brace appeared to be the method of choice. This g...

    journal_title:International orthopaedics

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Zwipp H,Hoffmann R,Thermann H,Wippermann BW

    更新日期:1991-01-01 00:00:00

  • Progressive lengthening of short congenital forearm stump in children for prosthetic fitting.

    abstract:PURPOSE:The sufficient length of congenital forearm stump is essential for prosthetic fitting. In our study we reviewed the results of a series of forearm stump lengthening, observed complications and their outcomes. We evaluated possibilities of combined technique to reduce or avoid problems and complications in forea...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Popkov D,Popkov A

    更新日期:2016-03-01 00:00:00

  • Synovial aspiration and serological testing in two-stage revision arthroplasty for prosthetic joint infection: evaluation before reconstruction with a mean follow-up of twenty seven months.

    abstract:INTRODUCTION:The two-stage revision protocol is the gold standard for controlling and treating low-grade prosthetic joint infections of total hip and total knee arthroplasty. The antibiotic pause for diagnostic reasons before reconstruction (stage two) is discussed in relation to the persistence of the infection and th...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Mühlhofer HML,Knebel C,Pohlig F,Feihl S,Harrasser N,Schauwecker J,von Eisenhart-Rothe R

    更新日期:2018-02-01 00:00:00

  • Early-stage osteonecrosis of the femoral head: where are we and where are we going in year 2018?

    abstract::Osteonecrosis of the femoral head (ONFH) is a devastating condition affecting relatively young patients whereby the femoral head is necrotic, resulting in significant pain, articular surface collapse, and eventual osteoarthritis. This condition has been highly associated with chronic steroid use, alcoholism, and hip t...

    journal_title:International orthopaedics

    pub_type: 杂志文章,评审


    authors: Larson E,Jones LC,Goodman SB,Koo KH,Cui Q

    更新日期:2018-07-01 00:00:00

  • Navigation improves the learning curve of transforamimal percutaneous endoscopic lumbar discectomy.

    abstract:PURPOSE:Beginners usually need increased punctures and dozens of fluoroscopy in learning transforamimal percutaneous endoscopic lumbar discectomy (tPELD). Navigator-assisted spinal surgery (NASS) is a novel technique that could induce a definite trajectory. The retrospective study aimed to investigate the impact of a d...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Fan G,Han R,Gu X,Zhang H,Guan X,Fan Y,Wang T,He S

    更新日期:2017-02-01 00:00:00

  • Structural bone allograft fractures in oncological procedures.

    abstract:PURPOSE:We report our experience analysing the risk of fracture amongst allografts in limb-preserving surgery for bone tumours. METHODS:We retrospectively reviewed our experience with bone allograft and its major complications when used for limb -preserving operations for bone tumours. Forty-one structural allografts ...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Garcia-Coiradas J,Garcia-Maroto R,Cebrian JL,Lopez-Duran L

    更新日期:2015-11-01 00:00:00

  • Is percutaneous kyphoplasty the better choice for minimally invasive treatment of neurologically intact osteoporotic Kümmell's disease? A comparison of two minimally invasive procedures.

    abstract:PURPOSE:The purpose of this study was to compare and evaluate the safety and efficacy of percutaneous vertebroplasty at a hyperextension position (PVPHP) and percutaneous kyphoplasty at a hyperextension position (PKPHP) for the treatment of osteoporotic Kümmell's disease. METHODS:This study was a retrospective, single...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Zhang J,Fan Y,He X,Meng Y,Huang Y,Jia S,Du J,Wu Q,Hao D

    更新日期:2018-06-01 00:00:00

  • Avascular necrosis of the femoral head: inter- and intraobserver variations of Ficat and ARCO classifications.

    abstract::Diagnosis of avascular necrosis (AVN) of the femoral head depends on the combination of clinical symptoms and evaluation of radiographs and/or magnetic resonance imaging (MRI). To evaluate the evolution of AVN, the Ficat and the Association Research Circulation Osseous (ARCO) classification are commonly used to assess...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Schmitt-Sody M,Kirchhoff C,Mayer W,Goebel M,Jansson V

    更新日期:2008-06-01 00:00:00

  • Osteogenic differentiation is synergistically influenced by osteoinductive treatment and direct cell-cell contact between murine osteoblasts and mesenchymal stem cells.

    abstract:PURPOSE:The present study was designed to address whether osteoblasts play a synergistic role in promoting mesenchymal stem cell (MSC) osteogenesis in a direct cell-cell contact co-culture model. METHODS:Murine C3H10T1/2 and MC3T3-E1 cell lines were mixed and plated onto 12-well culture plates and co-cultured at vario...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Tsai MT,Lin DJ,Huang S,Lin HT,Chang WH

    更新日期:2012-01-01 00:00:00

  • Long-term functional outcome and quality of life after successful surgical treatment of tibial nonunions.

    abstract:PURPOSE:Our aim was to evaluate quality of life (QoL) and functional outcome of patients with tibial nonunions after completion of surgical treatment with an average follow-up of five years. METHODS:The following data of 64 patients were retrospectively evaluated: fracture type, type and duration of surgical therapy, ...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Wichlas F,Tsitsilonis S,Disch AC,Haas NP,Hartmann C,Graef F,Schwabe P

    更新日期:2015-03-01 00:00:00

  • Pectoralis major transfer for the treatment of irreparable anterosuperior rotator cuff tears.

    abstract::The purpose of this study was to evaluate the outcome of subcoracoid pectoralis major transfer for the treatment of irreparable anterosuperior rotator cuff tears. This type of tear involves complete rupture of the subscapularis in combination with either the supraspinatus alone or the supraspinatus and infraspinatus. ...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Gavriilidis I,Kircher J,Magosch P,Lichtenberg S,Habermeyer P

    更新日期:2010-06-01 00:00:00

  • Short and long-arm fiberglass cast immobilization for displaced distal forearm fractures in children: a randomized controlled trial.

    abstract:PURPOSE:The aim of this study was to investigate whether short-arm fiberglass cast (SAC) immobilization provides fracture stabilization comparable to that of long-arm cast (LAC) treatment of displaced distal forearm fractures after closed reduction in paediatric patients. METHODS:A prospective, randomized, controlled ...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Seiler M,Heinz P,Callegari A,Dreher T,Staubli G,Aufdenblatten C

    更新日期:2020-09-17 00:00:00

  • Relationship between radiological and clinical variables in spondylolysis.

    abstract::A clinical and radiological follow-up investigation with at least 20 years observation time was made of 255 persons with lumbar spondylolysis with or without spondylolisthesis. The main purposes were to study the relationship between clinical and radiological features and to look for radiological and other variables o...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Saraste H,Nilsson B,Broström LA,Aparisi T

    更新日期:1984-01-01 00:00:00

  • A novel in vivo porcine model of intervertebral disc degeneration induced by cryoinjury.

    abstract:PURPOSE:Degenerative disc disease involves sequential events that lead to the loss of cells, a decrease in disc matrix production, disc dehydration, and alteration of its biomechanical properties. The aim of this study was to determine whether cryoinjury of the nucleus pulposus performed through endplate perforation co...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Flouzat-Lachaniette CH,Jullien N,Bouthors C,Beohou E,Laurent B,Bierling P,Dubory A,Rouard H

    更新日期:2018-09-01 00:00:00

  • Diagnosing acute compartment syndrome-where have we got to?

    abstract:PURPOSE:Acute compartment syndrome is a condition whereby tissue ischaemia occurs due to increased pressure in a closed myofascial compartment. It is a surgical emergency, with rapid recognition and treatment-the keys to good outcomes. METHODS:The available literature on diagnostic aids was reviewed by one of the seni...

    journal_title:International orthopaedics

    pub_type: 杂志文章,评审


    authors: McMillan TE,Gardner WT,Schmidt AH,Johnstone AJ

    更新日期:2019-11-01 00:00:00

  • Osteofibrous dysplasia of the tibia treated by bracing.

    abstract::Osteofibrous dysplasia of the tibia in children will commonly recur after surgical resection. The use of a leg brace until puberty offers a useful method of conservative management. Seven female patients, age three months to nine years at the time of brace treatment, have been followed for 3.5 to 18 years, an average ...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Akamatsu N,Hamada Y,Kohno H,Siddiqi NA

    更新日期:1992-01-01 00:00:00

  • Relationship of body mass index to early complications in hip replacement surgery : study performed at Hinchingbrooke Hospital, Orthopaedic Directorate, Huntingdon, Cambridgeshire.

    abstract::The purpose of this study was to evaluate the relationship between body mass index and early complications following total hip replacements. Five hundred and fifty patients who underwent primary total hip replacement were recruited. All these patients were subjected to a pre-operative assessment and follow-up at 6 wee...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Patel AD,Albrizio M

    更新日期:2007-08-01 00:00:00

  • Influence of weather variables on pain severity in end-stage osteoarthritis.

    abstract:PURPOSE:Patients often attribute increasing pain in an arthritic joint to changing weather patterns. Studies examining the impact of weather on pain severity have yielded equivocal and sometimes contradictory results. The relationship between subchondral pseudocysts and the role they play in this phenomenon has not bee...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Brennan SA,Harney T,Queally JM,O'Connor McGoona J,Gormley IC,Shannon FJ

    更新日期:2012-03-01 00:00:00

  • Postoperative changes of early-phase inflammatory indices after uncomplicated anterior cervical discectomy and fusion using allograft and demineralised bone matrix.

    abstract:PURPOSES:We investigated sequential levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in uncomplicated ACDF (anterior cervical discectomy and fusion) using allograft and DBM (demineralised bone matrix) for primary cervical spondylosis and/or disc herniation. To our knowledge, there has been no...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Kong CG,Kim YY,Park JB

    更新日期:2012-11-01 00:00:00

  • Effects of sagittal tibial osteotomy on frontal alignment of the knee and patellar height.

    abstract:AIM OF THE STUDY:The aim of this study was to evaluate the radiographic effect of sagittal tibial osteotomy (STO), flexion tibial osteotomy (FTO) and deflexion tibial osteotomy (DTO) around the knee. It has been hypothesized that proximal STO modifies patellar height and could cause varus/valgus changes of the anatomic...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Luceri F,Basilico M,Batailler C,Randelli PS,Peretti GM,Servien E,Lustig S

    更新日期:2020-11-01 00:00:00

  • Influence of cyclical mechanical loading on osteogenic markers in an osteoblast-fibroblast co-culture in vitro: tendon-to-bone interface in anterior cruciate ligament reconstruction.

    abstract:PURPOSE:We aimed to evaluate the influence of cyclical mechanical loading on osteoblasts and fibroblasts, and co-cultures of both in vitro, simulating the conditions of the tendon-to-bone interface in anterior cruciate ligament reconstruction. METHODS:Osteoblast-like cells (OBL) and tendon-derived rodent fibroblasts (...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Struewer J,Roessler PP,Schuettler KF,Ruppert V,Stein T,Timmesfeld N,Paletta JR,Efe T

    更新日期:2014-05-01 00:00:00

  • The kinematic relationship between sitting and standing posture and pelvic inclination and its significance to cup positioning in total hip arthroplasty.

    abstract:PURPOSE:The aim of this study is to describe the influence of sitting and standing posture on sagittal pelvic inclination in total hip replacement patients to assist with correct acetabular component positioning. METHODS:Lateral radiographs of the pelvis and lumbar spine in sitting and standing positions were extracte...

    journal_title:International orthopaedics

    pub_type: 杂志文章


    authors: Stephens A,Munir S,Shah S,Walter WL

    更新日期:2015-03-01 00:00:00