Vascular invasion in pancreatic cancer: Imaging modalities, preoperative diagnosis and surgical management.

Abstract:

:Pancreatic cancer is associated with a poor prognosis, and surgical resection remains the only chance for curative therapy. In the absence of metastatic disease, which would preclude resection, assessment of vascular invasion is an important parameter for determining resectability of pancreatic cancer. A frequent error is to misdiagnose an involved major vessel. Obviously, surgical exploration with pathological examination remains the "gold standard" in terms of evaluation of resectability, especially from the point of view of vascular involvement. However, current imaging modalities have improved and allow detection of vascular invasion with more accuracy. A venous resection in pancreatic cancer is a feasible technique and relatively reliable. Nevertheless, a survival benefit is not achieved by curative resection in patients with pancreatic cancer and vascular invasion. Although the discovery of an arterial invasion during the operation might require an aggressive management, discovery before the operation should be considered as a contraindication. Detection of vascular invasion remains one of the most important challenges in pancreatic surgery. The aim of this article is to provide a complete review of the different imaging modalities in the detection of vascular invasion in pancreatic cancer.

journal_name

World J Gastroenterol

authors

Buchs NC,Chilcott M,Poletti PA,Buhler LH,Morel P

doi

10.3748/wjg.v16.i7.818

subject

Has Abstract

pub_date

2010-02-21 00:00:00

pages

818-31

issue

7

eissn

1007-9327

issn

2219-2840

journal_volume

16

pub_type

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