Abstract：
:The lateral premotor cortex (PM) of the macaque monkey is an anatomically multifaceted area, which serves multiple sensorimotor and cognitive functions. While evidence for the functional organization of human premotor cortex accumulates, much less is known about the underlying anatomical properties of this brain region. We used diffusion tractography and functional magnetic resonance imaging (fMRI) to investigate whether the precentral gyrus in humans can be segregated on the basis of anatomical connectivity and of functional activation in a set of cognitive and motor tasks. Tractographic data suggested a distinction between ventral and dorsal premotor cortex, and furthermore inferior and superior subparcellation of both. Functional MRI data corroborated these four areas, showing that anatomical parcellation predicts the distribution of functional activation and vice versa (preliminary evidence). These results may encourage the application of combining diffusion tractography and fMRI in vivo in order to shed light on the correspondence of brain function and anatomy.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Schubotz RI,Anwander A,Knösche TR,von Cramon DY,Tittgemeyer Mdoi
10.1016/j.neuroimage.2009.12.069subject
Has Abstractpub_date
2010-04-01 00:00:00pages
396-408issue
2eissn
1053-8119issn
1095-9572pii
S1053-8119(09)01358-5journal_volume
50pub_type
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