Understanding the neural mechanisms involved in sensory control of voice production.

Abstract:

:Auditory feedback is important for the control of voice fundamental frequency (F0). In the present study we used neuroimaging to identify regions of the brain responsible for sensory control of the voice. We used a pitch-shift paradigm where subjects respond to an alteration, or shift, of voice pitch auditory feedback with a reflexive change in F0. To determine the neural substrates involved in these audio-vocal responses, subjects underwent fMRI scanning while vocalizing with or without pitch-shifted feedback. The comparison of shifted and unshifted vocalization revealed activation bilaterally in the superior temporal gyrus (STG) in response to the pitch shifted feedback. We hypothesize that the STG activity is related to error detection by auditory error cells located in the superior temporal cortex and efference copy mechanisms whereby this region is responsible for the coding of a mismatch between actual and predicted voice F0.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Parkinson AL,Flagmeier SG,Manes JL,Larson CR,Rogers B,Robin DA

doi

10.1016/j.neuroimage.2012.02.068

subject

Has Abstract

pub_date

2012-05-15 00:00:00

pages

314-22

issue

1

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(12)00253-4

journal_volume

61

pub_type

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