Abstract:
:We investigated the relation between cognitive processing speed and structural properties of white matter pathways via convergent imaging studies in healthy and brain-injured groups. Voxel-based morphometry (VBM) was applied to diffusion tensor imaging data from thirty-nine young healthy subjects in order to investigate the relation between processing speed, as assessed with the Digit-Symbol subtest from WAIS-III, and fractional anisotropy, an index of microstructural organization of white matter. Digit-Symbol performance was positively correlated with fractional anisotropy of white matter in the parietal and temporal lobes bilaterally and in the left middle frontal gyrus. Fiber tractography indicated that these regions are consistent with the trajectories of the superior and inferior longitudinal fasciculi. In a second investigation, we assessed the effect of white matter damage on processing speed using voxel-based lesion-symptom mapping (VLSM) analysis of data from seventy-two patients with left-hemisphere strokes. Lesions in left parietal white matter, together with cortical lesions in supramarginal and angular gyri were associated with impaired performance. These findings suggest that cognitive processing speed, as assessed by the Digit-Symbol test, is closely related to the structural integrity of white matter tracts associated with parietal and temporal cortices and left middle frontal gyrus. Further, fiber tractography applied to VBM results and the patient findings suggest that the superior longitudinal fasciculus, a major tract subserving fronto-parietal integration, makes a prominent contribution to processing speed.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Turken A,Whitfield-Gabrieli S,Bammer R,Baldo JV,Dronkers NF,Gabrieli JDdoi
10.1016/j.neuroimage.2008.03.057subject
Has Abstractpub_date
2008-08-15 00:00:00pages
1032-44issue
2eissn
1053-8119issn
1095-9572pii
S1053-8119(08)00286-3journal_volume
42pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::Successful social interactions rely upon the abilities of two or more people to mutually exchange information in real-time, while simultaneously adapting to one another. The neural basis of social cognition has mostly been investigated in isolated individuals, and more recently using two-person paradigms to quantify t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.03.003
更新日期:2014-07-01 00:00:00
abstract::Cognitive reward control (CRC) refers to the cognitive control of one's craving for hedonic stimuli, like food, sex, or drugs. Numerous functional magnetic resonance imaging (fMRI) studies have investigated neural sources of CRC. However, a consistent pattern of brain activation across stimulus types has not been iden...
journal_title:NeuroImage
pub_type: 杂志文章,meta分析
doi:10.1016/j.neuroimage.2019.07.008
更新日期:2019-10-15 00:00:00
abstract::Brain imaging studies in TEP, functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) have shown that visuospatial short-term memory tasks depend on dorsal parietofrontal networks. Knowing the spatiotemporal dynamics of this network would provide further understanding of the neural bases of the e...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2003.10.052
更新日期:2004-11-01 00:00:00
abstract:RATIONALE:Ketamine is a chiral molecule that is reported to model aspects of schizophrenia. OBJECTIVES:To investigate the stereospecificity of the isomers of ketamine using pharmacological magnetic resonance imaging (phMRI) in order to further understand ketamine's pharmacodynamic actions. METHOD:Responses to 25 mg k...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.05.022
更新日期:2006-10-01 00:00:00
abstract::Amnestic mild cognitive impairment (aMCI) can be classified into single domain (S-aMCI) and multiple domain (M-aMCI) subtypes. However, there have been no studies that specifically investigate the structural differences that support this classification. In an attempt to compare regional cortical thickness in two subty...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.02.042
更新日期:2007-06-01 00:00:00
abstract::ZNF804A rs1344706 is the first genetic risk variant to achieve genome wide significance for psychosis. Following earlier evidence that patients carrying the ZNF804A risk allele had relatively spared memory function compared to patient non-carriers, we investigated whether ZNF804A was also associated with variation in ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.09.089
更新日期:2011-02-01 00:00:00
abstract::Obesity is a health problem that has become a major focus of attention in recent years. There is growing evidence of an association between obesity and differences in reward processing. However, it is not known at present whether these differences are linked exclusively to food, or whether they can be detected in othe...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.10.035
更新日期:2013-02-01 00:00:00
abstract::The issue of whether speech is supported by the same neural substrates as non-speech vocal tract gestures has been contentious. In this fMRI study we tested whether producing non-speech vocal tract gestures in humans shares the same functional neuroanatomy as non-sense speech syllables. Production of non-speech vocal ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.03.032
更新日期:2009-08-01 00:00:00
abstract::The serotonin transporter (SERT) modulates the entire serotonergic system in the brain and influences both the dopaminergic and norepinephrinergic systems. These three systems are intimately involved in normal physiological functioning of the brain and implicated in numerous pathological conditions. Here we use high-r...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.03.026
更新日期:2009-07-15 00:00:00
abstract::Trace conditioning refers to a learning process occurring after repeated presentation of a neutral conditioned stimulus (CS+) and a salient unconditioned stimulus (UCS) separated by a temporal gap. Recent studies have reported that trace conditioning can occur in humans in reduced levels of consciousness by showing a ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.07.039
更新日期:2016-11-01 00:00:00
abstract::The interpretation of the blood-oxygenation level-dependent (BOLD) post-stimulus undershoot has been a topic of considerable interest, as the mechanisms behind this prominent BOLD transient may provide valuable clues on the neurovascular response process and energy supply routes of the brain. Biomechanical theories ex...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.03.015
更新日期:2009-07-01 00:00:00
abstract::Intraoperative Thermal Imaging (ITI) is a novel neuroimaging technique that can potentially locate the margins of primary and metastatic brain tumors. As a result, the additional real-time anatomical and pathophysiological information may significantly contribute to an improved extent of tumor resection. Our objective...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2009.03.043
更新日期:2009-08-01 00:00:00
abstract::In current fMRI studies designed to map BOLD changes related to interictal epileptiform discharges (IED), which are recorded on simultaneous EEG, the information contained in the morphology and field extent of the EEG events is exclusively used for their classification. Usually, a BOLD predictor based on IED onset tim...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.08.001
更新日期:2016-11-15 00:00:00
abstract::Chemical exchange between water and labile protons from amino-acids, proteins and other molecules can be exploited to provide tissue contrast with magnetic resonance imaging (MRI) techniques. Using an off-resonance Spin-Locking (SL) scheme for signal preparation is advantageous because the image contrast can be tuned ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.08.014
更新日期:2012-01-16 00:00:00
abstract::Deep neural networks are increasingly being used in both supervised learning for classification tasks and unsupervised learning to derive complex patterns from the input data. However, the successful implementation of deep neural networks using neuroimaging datasets requires adequate sample size for training and well-...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.05.049
更新日期:2018-09-01 00:00:00
abstract::We used magnetic resonance imaging (MRI) and cortical pattern matching to map differences in cortical gray matter deficits between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), and explored the possible influence of gender on these patterns. Twenty-nine patients with AD (age 77.9 +/- 5.5), 16 patients ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2004.04.026
更新日期:2004-09-01 00:00:00
abstract::Any motor action results from a dynamic interplay of various brain regions involved in different aspects of movement preparation and execution. Establishing a reliable model of how these areas interact is crucial for a better understanding of the mechanisms underlying motor function in both healthy subjects and patien...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.03.048
更新日期:2008-07-15 00:00:00
abstract::Recently proposed dynamic magnetic resonance (MR) inverse imaging (InI) is a novel parallel imaging reconstruction technique capable of improving the temporal resolution of blood-oxygen level-dependent (BOLD) contrast functional MRI (fMRI) to the order of milliseconds at the cost of moderate spatial resolution. Volume...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.11.072
更新日期:2011-03-01 00:00:00
abstract::It is generally believed that alpha band (8-12 Hz) electric and magnetic activity in the area of the left and right temporal regions in the human brain are at best poorly correlated. There are no previous reports of very high alpha band correlation between left and right temporal regions by magnetoencephalography (MEG...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2004.04.016
更新日期:2004-08-01 00:00:00
abstract::Some eighty years after the discovery of the human electroencephalogram (EEG) and its dominant rhythm, alpha (~10Hz), the neurophysiological functions and behavioral correlates of alpha oscillations are still under debate. Similarly, the biological mechanisms contributing to the general factor of intelligence, or g, h...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.04.059
更新日期:2013-10-01 00:00:00
abstract::For nontonal language speakers, speech processing is lateralized to the left hemisphere and musical processing is lateralized to the right hemisphere (i.e., function-dependent brain asymmetry). On the other hand, acoustic temporal processing is lateralized to the left hemisphere and spectral/pitch processing is latera...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.02.080
更新日期:2013-12-01 00:00:00
abstract::Results of this PET-O15 water activation study confirm the implication of supplementary motor areas during time estimation tasks. They also show that the cortical-subcortical network associated with temporal processing is impaired in schizophrenia. Following recent proposals of time dynamic networks, this impairment m...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2004.09.010
更新日期:2005-01-15 00:00:00
abstract::Spatiotemporal filtering and amplification of sensory information at multiple levels during the generation of perceptual representations is a fundamental processing principle of the nervous system. While for the visual and auditory system temporal filtering of sensory signals has been noticed for a long time, respecti...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.09.003
更新日期:2018-12-01 00:00:00
abstract::We use an fMRI adaptation paradigm to explore the selectivity of human responses in the lateral geniculate nucleus (LGN) and superior colliculus (SC) to red-green color and achromatic contrast. We measured responses to red-green (RG) and achromatic (ACH) high contrast sinewave counter-phasing rings with and without ad...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.04.067
更新日期:2016-09-01 00:00:00
abstract::Voxel-based morphometry (VBM) allows the output of structural data in a Statistical Parametric Map of the brain in the same way that the SPM can do with functional data. Using functional magnetic resonance (fMR), we studied brain activation in 14 patients with schizophrenia and 14 matched normal controls. We found sig...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuroimage.2003.10.027
更新日期:2004-03-01 00:00:00
abstract::Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder diagnosed on the basis of motor symptoms, but that also includes cognitive and visuo-spatial deficits. Though PD is known to initially affect subcortical regions, the cortex also exhibits neuronal loss in the course of the disease as post mortem studi...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.12.043
更新日期:2011-03-15 00:00:00
abstract::Spherical deconvolution methods have been applied to diffusion MRI to improve diffusion tensor tractography results in brain regions with multiple fibre crossing. Recent developments, such as the introduction of non-negative constraints on the solution, allow a more accurate estimation of fibre orientations by reducin...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.09.033
更新日期:2010-01-15 00:00:00
abstract::Cognition that is not based on perception can lead to at least two different outcomes. In some situations, cognition that is independent of perception can allow actions to be selected other than those prescribed by immediate perceptual input. In others, cognition can be independent of perception and unrelated to the c...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.12.012
更新日期:2013-04-01 00:00:00
abstract::While the role of synchronized oscillatory activity in the gamma-band frequency range for conscious perception is well established in the visual domain, there is limited evidence concerning neurophysiological mechanisms in conscious auditory perception. In the current study, we addressed this issue with 64-channel EEG...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.06.012
更新日期:2014-10-15 00:00:00
abstract::MRI based on T1 relaxation contrast is increasingly being used to study brain morphology and myelination. Although it provides for excellent distinction between the major tissue types of gray matter, white matter, and CSF, reproducible quantification of T1 relaxation rates is difficult due to the complexity of the con...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.12.032
更新日期:2016-03-01 00:00:00