Abstract:
PURPOSE:To determine the feasibility of diffusion-weighted magnetic resonance (MR) imaging (DWI) of uterine cervical cancer and to investigate whether the apparent diffusion coefficient (ADC) values of cervical cancer differ from those of normal cervix and whether they could indicate the histologic type and the pathologic grade of tumor. MATERIALS AND METHODS:Forty-two female patients with histopathologically proven uterine cervical cancer and 15 female patients with uterine leiomyomas underwent preoperative MR examinations using a 1.5-T clinical scanner (GE 1.5T Twin-Speed Infinity with Excite II scanner; GE Healthcare, Waukesha, Wis). Scanning sequences included T2-weighted fast spin-echo imaging, T2-weighted fast spin-echo with fat suppression imaging, T1-weighted spin-echo imaging, and DWI with diffusion factors of 0 and 1000 s/mm2. Parameters evaluated consisted of ADC values of uterine cervical cancer and normal cervix. Histologic specimens were stained with hematoxylin and eosin. The cellular densities of 32 uterine cervical cancers were calculated, which were regarded as the ratio of the total area of tumor cell nuclei divided by the area of sample image. RESULTS:Apparent diffusion coefficient value was statistically different (P = 0.000) between normal and cancerous tissue in the uterine cervix; the former one was (mean [SD], 1.50 [0.16]) x 10(-3) mm2/s, and the latter one was (0.88 [0.15]) x 10(-3) mm2/s. Apparent diffusion coefficient value of squamous carcinoma was statistically lower than that of adenocarcinoma (P = 0.040). The ADC value of uterine cervical cancer correlated negatively with cellular density (r = -0.711, P = 0.000) and the grading of tumor (r = -0.778, P = 0.000). CONCLUSIONS:Diffusion-weighted MR imaging has a potential ability to differentiate between normal and cancerous tissue in the uterine cervix, and it can indicate the histologic type of uterine cervical cancer as well. The ADC value of uterine cervical cancer represents tumor cellular density, thus providing a new method for evaluating the pathologic grading of tumor.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Liu Y,Bai R,Sun H,Liu H,Wang Ddoi
10.1097/RCT.0b013e31819e93afsubject
Has Abstractpub_date
2009-11-01 00:00:00pages
858-62issue
6eissn
0363-8715issn
1532-3145pii
00004728-200911000-00008journal_volume
33pub_type
杂志文章abstract::In 95% of cases, computed tomography (CT) enables the articular capsule of the hip joint to be directly visualized. Articular effusion in the hip joint can also be recognized in the CT image. In inflammatory arthritis and active osteoarthrosis of the hip joint, thickening of the articular capsule or articular effusion...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198304000-00014
更新日期:1983-04-01 00:00:00
abstract::The purpose of this report is to describe a further distinctive cause of crazy-paving pattern on thin-section computed tomography in a patient affected by pulmonary granulomatous mycosis fungoides. It was possible to reconcile the crazy-paving appearance on thin-section computed tomography scan with the histopathologi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000214269.72180.64
更新日期:2006-09-01 00:00:00
abstract:INTRODUCTION:Patients with type II navicular ossicles have traditionally been considered to be symptomatic, whereas patients with type I and III bones are considered asymptomatic without additional relevant imaging findings. The main objective of this study is to investigate the association of type I os naviculare with...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000001089
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To assess whether cardiac computed tomographic angiography (CCTA) can quantify the severity of chronic mitral regurgitation (MR) compared to qualitative and quantitative echocardiographic parameters. MATERIALS AND METHODS:Cardiac computed tomographic angiography was performed in 23 patients (mean ± SD age, 63 ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31822d28b8
更新日期:2011-09-01 00:00:00
abstract::Based on a pool of 24 selected cases of nontraumatic pathology of the hand and wrist in patients under the age of 18 years, collected from three pediatric hospitals, the authors have illustrated a number of congenital, inflammatory, and infectious conditions as well as tumors of bones and soft tissues, utilizing MRI w...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199803000-00018
更新日期:1998-03-01 00:00:00
abstract:PURPOSE:The purpose of the study was to explore the feasibility and repeatability of diffusion tensor imaging and diffusion tractography on the anterior cruciate ligament graft after reconstruction and determine the fractional anisotropy and mean apparent diffusion coefficient values. MATERIALS AND METHODS:Twenty-two ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000198
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the efficacy of test injection technique using a monitoring scan at knee level for 64-slice multidetector row computed tomographic (MDCT) angiography of the abdominal and lower extremity arteries. METHODS:The test injection technique using low-dose serial CT scan at knee level was performed for ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181674063
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND AND AIMS:To prospectively determine the accuracy of liver fat quantification with magnetic resonance imaging (MRI). PATIENTS AND METHODS:The population consisted of 40 patients (mean age, 52.5 years; range, 23-78 years). The same day, all patients underwent MRI and ultrasonography-guided liver biopsy. The h...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318199d883
更新日期:2009-09-01 00:00:00
abstract::Recurrent respiratory papillomatosis is a chronic disease of children and young adults associated with various complications, one of which is malignant change. We report CT findings of malignant change in a case of recurrent respiratory papillomatosis. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199509000-00020
更新日期:1995-09-01 00:00:00
abstract::Magnetic susceptibility variations due to the presence of iron in neural tissue can result in a shift of local resonance frequency, decreased T2 resulting from water diffusion through local field gradients, and line broadening due to field inhomogeneity within a voxel. In this study, modified spin echo phase contrast ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198803000-00014
更新日期:1988-03-01 00:00:00
abstract:PURPOSE:To compare the efficacy and patient tolerance of iohexol and meglumine sodium diatrizoate as oral contrast agents for computed tomography (CT). SUBJECTS AND METHODS:One hundred patients were randomly assigned to drink 1000 mL of either meglumine sodium diatrizoate or iohexol 350 before their abdominopelvic CT ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,随机对照试验
doi:10.1097/RCT.0b013e3182058e76
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:Our goal was to investigate the role of Gd-DTPA-enhanced dynamic MRI in the evaluation of renal ischemic lesions. METHOD:With a turbo FLASH sequence before and after injection of Gd-DTPA, nine foxhound dogs after 60-120 min of renal ischemia underwent MR examination. In addition, five patients with a tumor in ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199603000-00013
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe the characteristics of lung cancers in patients with tuberculous fibrothorax or empyema. METHODS:We retrospectively evaluated 138 consecutive patients with a diagnosis of lung cancer combined with fibrothorax (n = 127) or empyema (n = 11) from January 2005 to May 2015. A...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000608
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the causes of apparent diffusion coefficient (ADC) measurement errors and to determine the optimal scanning parameters that are independent of the field strength and vendors of the magnetic resonance (MR) system. MATERIALS AND METHODS:Brain MR images of 10 healthy volu...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000266
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the usefulness of z-score mapping method on neuroradiologists' performance in quantification of the extent of hypoattenuation regions of hyperacute stroke on unenhanced computed tomographic (CT) images by using the Alberta Stroke Programme Early CT Score system. METH...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181e66473
更新日期:2010-09-01 00:00:00
abstract::Diffuse low attenuation lesions on CT scans are caused by various pathologic conditions, especially differences of the intratumoral matrix. Low attenuation on CT scans was more defined than fat density and less than muscle density, the so-called near water density. We present representative cases of low attenuation le...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-200009000-00018
更新日期:2000-09-01 00:00:00
abstract::Fibrodysplasia ossificans progressiva is a rare disorder characterized by progressive heterotopic bone formation in connective tissue and muscle in association with congenital skeletal anomalies. The disease usually leads to extensive immobility and eventual disability. We report the magnetic resonance findings in a b...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199003000-00035
更新日期:1990-03-01 00:00:00
abstract::Flow phenomena occurring after the bolus injection of contrast material can simulate the presence of pathology on thoracic computed tomography. In a review of 50 dynamic scans performed after contrast medium injection, apparent filling defects in the superior vena cava were seen in 46. In four cases, retrograde fillin...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198206000-00004
更新日期:1982-06-01 00:00:00
abstract:OBJECTIVE:We examined the relationship between the perfusion reserve as measured by acetazolamide (ACZ)-challenge N-isopropyl-I-123-p-iodoamphetamine (IMP)-single-photon emission computed tomography (SPECT) and the degree of leukoaraiosis (LA) as estimated using magnetic resonance imaging. METHODS:In 51 patients recei...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318038fc5d
更新日期:2007-11-01 00:00:00
abstract::Two patients with phenylketonuria are reported with white matter lesions. Diffusion magnetic resonance (MR) imaging revealed restricted diffusion patterns (high signal) on b = 1000 s/mm2 images associated with low apparent diffusion coefficient values ranging between 0.44 x 10-3 mm2/s and 0.56 x 10-3 mm2/s. On proton ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200307000-00016
更新日期:2003-07-01 00:00:00
abstract::The article presents a case of subacute coronary artery thrombosis investigated by classic methods, coronary angiography, and MRI. T1- and T2-weighted images showed high signal intensity within the lumen of the right coronary artery corresponding to the methemoglobin content of the thrombus. Dynamic sequence images wi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199711000-00020
更新日期:1997-11-01 00:00:00
abstract::A method is outlined for obtaining direct longitudinal computed tomograms of the forearm using a conventional total body scanner. A case is described in which longitudinal scanning helped define a soft tissue tumor of the forearm and thereby assisted in surgical planning. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198102000-00029
更新日期:1981-02-01 00:00:00
abstract::The effect of hemodialysis on the CT absorption value of the liver was examined in 14 hemodialysis patients. In the high ultrafiltration group [10 patients with a weight loss of -1.7 to -3.5 (2.9 +/- 0.6) kg], the hepatic CT absorption value increased from 49.6 +/- 7.0 to 58.7 +/- 8.7 Hounsfield units (p less than 0.0...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198408000-00021
更新日期:1984-08-01 00:00:00
abstract:PURPOSE:To compare the volume rendering (VR) and maximum intensity projection (MIP) computed tomography angiography (CTA) techniques using multidetector-row CT for hepatic artery evaluation of potential donors for living donor liver transplantation (LDLT). METHOD:Over a 9-month period, CTA using multidetector-row CT a...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200303000-00004
更新日期:2003-03-01 00:00:00
abstract::The density distribution inside a pathologic zone before and after contrast enhancement has been studied in the computed tomograms of 88 cases of cerebral and orbital tumors, using histographic analysis. The histograms provided additional diagnostic information, especially for vascular tumors. This method is also usef...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197704000-00014
更新日期:1977-04-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to investigate whether the criterion "maximum depth of intraluminal appendiceal fluid greater than 2.6 mm" ("DEPTH >2.6 mm"), with the use of 64-detector row computed tomography, is useful to diagnose appendicitis. METHODS:We retrospectively evaluated 0.68-mm-thick images of 2...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182324443
更新日期:2011-11-01 00:00:00
abstract::Although acute appendicitis is the most common disease of the appendix, the appendix can be involved by a wide range of diseases. Diseases other than acute appendicitis may produce signs and symptoms indistinguishable from those of acute appendicitis. Computed tomography (CT) can provide important information for diag...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-200305000-00001
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:Balò concentric sclerosis is a rare demyelinating disorder. Serial proton magnetic resonance spectroscopic (1H-MRS) studies were carried out to better understand the biochemical changes within concentric lesions. MATERIALS AND METHODS:Five concentric lesions in four patients with Balò concentric sclerosis we...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200109000-00008
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to develop and validate a novel noise insertion method that can accurately simulate lower-dose images from existing standard-dose computed tomography (CT) data. METHODS:The noise insertion method incorporates the effects of the bowtie filter, automatic exposure control, and el...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318258e891
更新日期:2012-07-01 00:00:00
abstract::Urachal carcinoma arises in the clinically silent extraperitoneal space between the bladder apex and the umbilicus. Computed tomography was used to correctly diagnose and stage urachal cancer in two patients. In one case a mass was localized to the bladder wall and immediate juxtavesical region; in the other case an a...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-198811000-00014
更新日期:1988-11-01 00:00:00