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Identification of two somatostatin-immunoreactive cell types in the principal islet of Sparus auratus L. (Teleostei) by immunogold staining.

Abstract：

:Two types of somatostatin (SST 14)-immunoreactive cells are identified by immunogold staining in the Lowicryl-embedded principal islet of Sparus auratus: D1 cells, having large moderate to low electron dense granules, located between A cells in the islet periphery and D2 cells, containing smaller electron-dense granules, present between B cells in the central region of the islet. Although SST 28-like immunoreactivity was not observed in D cells of S. auratus, the presence of SST 14 and a SST 22-,25-, or 28-like sequence in D2 and D1 cells, respectively, is discussed. A third SST 14-immunoreactive cell, found in the islet periphery, showed immunoreactive D1- and unreactive A-like granules. This cell type, which has a pyknotic-like nucleus and a dark appearance in osmicated Epon-embedded tissue, is supposed to be the product of fusion of D1 and A cells.

journal_name

Gen Comp Endocrinol

journal_title

General and comparative endocrinology

authors

Abad ME,Lozano MT,Taverne-Thiele JJ,Rombout JH

doi

10.1016/0016-6480(90)90199-v

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

1-8

issue

1

eissn

0016-6480

issn

1095-6840

journal_volume

77

pub_type

杂志文章

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