Abstract:
:We report on an acute myeloid leukemia in a neonate whose mother was exposed to diethylstilboestrol in utero. The newborn presented with leukemia cutis, hemorrhagic skin lesions, hyperleucocytosis and disseminated intravascular coagulation. A bone marrow examination confirmed the diagnosis of acute monocytic leukemia with a t(11;19) MLL-ELL fusion transcript. Chemotherapy was initiated but the child developed a bilateral pulmonary infection that led to fatal respiratory distress. This case shows acute myeloid leukemia and the third pediatric leukemia reported after maternal diethylstilboestrol exposure.
journal_name
Pediatr Blood Cancerjournal_title
Pediatric blood & cancerauthors
Chantrain CF,Sauvage D,Brichard B,Dupont S,Poirel HA,Ameye G,De Weer A,Vandenberghe P,Detaille T,Anslot C,de Cléty SC,Vermylen Cdoi
10.1002/pbc.22040subject
Has Abstractpub_date
2009-08-01 00:00:00pages
220-2issue
2eissn
1545-5009issn
1545-5017journal_volume
53pub_type
杂志文章abstract:BACKGROUND:There is little information about factors modulating bone mineral density (BMD) in survivors of childhood acute lymphoblastic leukemia (ALL). PROCEDURE:We analyzed data from 57 survivors (26 male, 52 Caucasian) who underwent two serial quantitative computed tomography (QCT) studies of BMD. Using multiple li...
journal_title:Pediatric blood & cancer
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journal_title:Pediatric blood & cancer
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pub_type: 评论,杂志文章
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