Abstract:
:Hepatoblastoma (HB) and biliary atresia (BA) are both rare conditions that occurred in the patient described. This is the second such case in the literature. An explanation for this apparent coincidence could possibly be found in the existance of pluripotent liver stem cells. In humans, small epithelial cells (SEC) behave as pluripotent stem cells. These are cells that can develop as biliary epithelial cells or as liver parenchymal cells, and are thought to be the precursor cell of HB. They are present in a much higher concentration in the livers of patients with BA, which may make them prone to develop HB.
journal_name
Pediatr Blood Cancerjournal_title
Pediatric blood & cancerauthors
Taat F,Bosman DK,Aronson DCdoi
10.1002/pbc.20115keywords:
subject
Has Abstractpub_date
2004-10-01 00:00:00pages
603-5issue
5eissn
1545-5009issn
1545-5017journal_volume
43pub_type
杂志文章abstract:BACKGROUND:Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms have been implicated in childhood acute lymphoblastic leukemia (ALL) risk, but previously published studies were inconsistent and recent meta-analyses were not adequate. PROCEDURES:In a meta-analysis of 21 publications with 4,706 cas...
journal_title:Pediatric blood & cancer
pub_type: 杂志文章,meta分析,评审
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更新日期:2010-04-01 00:00:00
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pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2020-04-01 00:00:00
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更新日期:2010-12-01 00:00:00
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