Safety of central venous catheter placement at diagnosis of acute lymphoblastic leukemia in children.

abstract：PURPOSE:This pilot study was done to determine the feasibility and accuracy of University of Florida/National Cancer Institute (UF/NCI) phantoms and Monte Carlo (MC) retrospective dosimetry and had two aims: (1) to determine the anatomic accuracy of UF/NCI phantoms by comparing 3D organ doses in National Wilms Tumor St...

journal_title：Pediatric blood & cancer

authors： Kalapurakal JA,Gopalakrishnan M,Mille M,Helenowski I,Peterson S,Rigsby C,Laurie F,Jung JW,Fitzgerald TJ,Lee C

更新日期：2018-12-01 00:00:00

abstract：:We report two cases of primary CNS lymphoma (PCNSL) treated with high-dose methotrexate. Though standard adult treatment of PCNSL incorporates whole-brain radiotherapy, the literature suggests it may be possible to delay or avoid radiotherapy and the associated increased risk of neurologic sequelae in pediatric patien...

journal_title：Pediatric blood & cancer

authors： Shah AC,Kelly DR,Nabors LB,Oakes WJ,Hilliard LM,Reddy AT

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Radiation therapy (RT)-induced effects in children treated for low grade glioma (LGG) can result in worsening of neurologic symptoms and clinical and radiographic deterioration. Treatment for radiation-induced tumor enlargement is based on symptom control and usually involves steroids. PROCEDURE:We conducte...

journal_title：Pediatric blood & cancer

authors： Foster KA,Ares WJ,Pollack IF,Jakacki RI

更新日期：2015-02-01 00:00:00

abstract：:Medulloblastomas (MB) are classified in four subgroups: the well defined WNT and Sonic Hedgehog (SHH) subgroups, and the less defined groups 3 and 4. They occasionally occur in the context of a cancer predisposition syndrome. While germline APC mutations predispose to WNT MB, germline mutations in SUFU, PTCH1, and TP5...

journal_title：Pediatric blood & cancer

authors： Bourdeaut F,Miquel C,Richer W,Grill J,Zerah M,Grison C,Pierron G,Amiel J,Krucker C,Radvanyi F,Brugieres L,Delattre O

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Advanced irradiation techniques, including intensity-modulated radiation therapy (IMRT), aim to limit irradiation to adjoining tissues by conforming beams to a well-defined volume. In intracranial germinomas, whole-ventricular IMRT decreases the volume of irradiation to surrounding parenchyma. This study exa...

journal_title：Pediatric blood & cancer

authors： Toll SA,Jones MT,Yoshida EJ,Dhall G,Olch AJ,Wong KK

更新日期：2019-12-01 00:00:00

abstract：:Evidence of the laboratory benefits of hydroxyurea and its clinical efficacy in reducing acute vaso-occlusive events in adults and children with sickle cell anemia has accumulated for more than 15 years. A definitive clinical trial showing that hydroxyurea can also prevent organ damage might support widespread use of ...

journal_title：Pediatric blood & cancer

authors： Thompson BW,Miller ST,Rogers ZR,Rees RC,Ware RE,Waclawiw MA,Iyer RV,Casella JF,Luchtman-Jones L,Rana S,Thornburg CD,Kalpatthi RV,Barredo JC,Brown RC,Sarnaik S,Howard TH,Luck L,Wang WC

更新日期：2010-02-01 00:00:00

abstract：:Because of increasing survival rates in pediatric oncology, attention is focusing on cancer and its treatment-related side effects. Rehabilitation may reduce their impact. However, the literature does not provide strong evidence regarding rehabilitation pathways. Therefore, the Italian Association of Pediatric Hematol...

journal_title：Pediatric blood & cancer

authors： Rossi F,Ricci F,Botti S,Bertin D,Breggiè S,Casalaz R,Cervo M,Ciullini P,Coppo M,Cornelli A,Esposito M,Ferrarese M,Ghetti M,Longo L,Morri M,Naretto G,Orsini N,Fagioli F,AIEOP Rehabilitation Working Group Members.

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Most patients with stage IV Wilms tumor (WT) and pulmonary metastases are treated with surgery, local radiotherapy (RT), and whole-lung irradiation (WLI). The Children's Oncology Group is studying whether WLI should only be given if metastatic lung lesions persist following induction chemotherapy. We hypothe...

journal_title：Pediatric blood & cancer

authors： Farooqi A,Siddiqi A,Khan MK,Esiashvili N

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:The use of carboplatin for the treatment of pediatric low grade gliomas (PLGG) is often limited by the development of carboplatin hypersensitivity. Reported rates of carboplatin hypersensitivity reactions vary between 6% and 32% in these patients. Here we report the frequency of carboplatin hypersensitivity ...

journal_title：Pediatric blood & cancer

authors： Dodgshun AJ,Hansford JR,Cole T,Choo S,Sullivan MJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Primary mediastinal germ cell tumors (GCTs) are rare in children and still represent a challenge for both adult and pediatric oncologists because of their worse outcome compared to their gonadal counterpart. PROCEDURE:Prospectively collected data concerning patients enrolled in the Italian Association of Pe...

journal_title：Pediatric blood & cancer

authors： De Pasquale MD,Crocoli A,Conte M,Indolfi P,D'Angelo P,Boldrini R,Terenziani M,Inserra A

更新日期：2016-05-01 00:00:00

abstract：:Familial adenomatous polyposis (FAP) due to APC mutation is associated with an increased risk of hepatoblastoma. All cases of hepatoblastoma in patients with FAP reported in the literature were reviewed. One hundred and nine patients were identified. Thirty-five patients (of 49 with data) were diagnosed with hepatobla...

journal_title：Pediatric blood & cancer

authors： Trobaugh-Lotrario AD,López-Terrada D,Li P,Feusner JH

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Currently, there is no standardized treatment for adolescents, aged 15 years or older, with mature B-cell non-Hodgkin lymphoma (B-NHL), although this age group has been reported to have a poorer prognosis than younger patients. PROCEDURE:The present study analyzed the data of 321 patients with B-NHL, enroll...

journal_title：Pediatric blood & cancer

authors： Sekimizu M,Hashimoto H,Mori T,Kobayashi R,Horibe K,Tsurusawa M

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The treatment of central nervous system (CNS) germ cell tumors (GCT) remains controversial. The purpose of this study was to demonstrate efficacy of a chemotherapy only strategy, with less morbidity, when compared to regimens with irradiation. METHODS:Between January 2001 and December 2004 newly diagnosed p...

journal_title：Pediatric blood & cancer

authors： da Silva NS,Cappellano AM,Diez B,Cavalheiro S,Gardner S,Wisoff J,Kellie S,Parker R,Garvin J,Finlay J

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Pediatric health-related quality of life (HRQOL) questionnaires have been validated in children with sickle cell disease (SCD), but small sample sizes in these studies have limited clinical comparisons. We used the baseline clinical data from the Collaborative Data (C-Data) Project of the Comprehensive Sickl...

journal_title：Pediatric blood & cancer

authors： Dampier C,Lieff S,LeBeau P,Rhee S,McMurray M,Rogers Z,Smith-Whitley K,Wang W,Comprehensive Sickle Cell Centers (CSCC) Clinical Trial Consortium (CTC).

更新日期：2010-09-01 00:00:00

abstract：:Diffuse intrinsic pontine glioma (DIPG) is characterized by a short history of brainstem symptoms and well-known magnetic resonance imaging features with a fatal outcome. However, we report three unusual cases of brainstem tumors with an initial indolent and protracted course, which subsequently developed the classica...

journal_title：Pediatric blood & cancer

authors： Baroni LV,Solano-Paez P,Nobre L,Michaeli O,Hawkins C,Laughlin S,Bartels U,Ramaswamy V,Bouffet E

更新日期：2020-03-01 00:00:00

abstract：:A 17-year-old girl with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with persistent minimal residual disease (MRD) who underwent standard chemotherapy was found to have a BCR-ABL1-like gene expression pattern. Genome sequencing revealed a JAK2 mutation not previously described in BCP-ALL and a potential th...

journal_title：Pediatric blood & cancer

authors： Mayfield JR,Czuchlewski DR,Gale JM,Matlawska-Wasowska K,Vasef MA,Nickl C,Pickett G,Ness SA,Winter SS

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Central nervous system irradiation (CNS-RT) has played a central role in the cure of acute lymphoblastic leukemia (ALL), but due to the risk of long-term toxicity, it is now considered a less-favorable method of CNS-directed therapy. PROCEDURES:Retrospectively, we estimated the effect of CNS involvement and...

journal_title：Pediatric blood & cancer

authors： Taskinen M,Oskarsson T,Levinsen M,Bottai M,Hellebostad M,Jonsson OG,Lähteenmäki P,Schmiegelow K,Heyman M

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Undernutrition impacts clinical outcome adversely in children with cancer. This study aimed to validate a nutritional algorithm with specific application to the low- and middle-income country (LMIC) setting. PROCEDURE:Fifty children with a new diagnosis of cancer were enrolled in this randomized interventio...

journal_title：Pediatric blood & cancer

authors： Totadri S,Trehan A,Mahajan D,Viani K,Barr R,Ladas EJ

更新日期：2019-12-01 00:00:00

abstract：:Adherence is a critical consideration in ongoing efforts to improve outcomes among adolescents and young adults (AYAs) with cancer. In this narrative review, we embed existing conceptualizations of adherence within a developmental context to provide a novel vantage point from which to examine this important issue. App...

journal_title：Pediatric blood & cancer

authors： Vandermorris A,Sampson L,Korenblum C

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Ispinesib is a highly specific inhibitor of kinesin spindle protein (KSP, HsEg5), a mitotic kinesin required for separation of the spindle poles. Here we report the activity of ispinesib against the in vitro and in vivo panels of the Pediatric Preclinical Testing Program (PPTP). PROCEDURES:Ispinesib was tes...

journal_title：Pediatric blood & cancer

authors： Carol H,Lock R,Houghton PJ,Morton CL,Kolb EA,Gorlick R,Reynolds CP,Maris JM,Keir ST,Billups CA,Smith MA

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:Despite the presence of reports on correlation between major congenital defects and cancer, very few studies have investigated the frequency of minor anomalies in childhood malignancy. The aim of this study was to determine the prevalence of minor anomalies in children with hematological malignancy. PROCEDU...

journal_title：Pediatric blood & cancer

authors： Citak FE,Citak EC,Akkaya E,Kosan B,Ezer U,Kurekci AE

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Many pediatric oncology patients undergoing hematopoietic stem cell transplantation (HSCT) require nutritional support (NS) because of their inability to consume adequate caloric intake enough calories orally. Although NS can be provided either enteraly (EN) or parenteraly (PN), EN is the preferred method of...

journal_title：Pediatric blood & cancer

authors： Williams-Hooker R,Adams M,Havrilla DA,Leung W,Roach RR,Mosby TT

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To determine the safety, efficacy, and PK profile of intravenous busulfan (Bu) in the context of a Bu and cyclophosphamide (IVBuCy) preparative regimen in children undergoing allogeneic hematopoietic stem cell transplantation (HSCT). METHODS:Twenty-four children were enrolled in an open-label, multicenter tria...

journal_title：Pediatric blood & cancer

authors： Wall DA,Chan KW,Nieder ML,Hayashi RJ,Yeager AM,Kadota R,Przepiorka D,Mezzi K,Kletzel M,Pediatric Blood, Marrow Transplant Consortium.

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Veno-occlusive disease (VOD) is a major complication following hematopoietic stem cell transplantation (HSCT). Its diagnosis is based on clinical criteria, which have a limited sensitivity. Increased plasminogen activator inhibitor-1 (PAI-1) levels have been suggested as a marker of VOD. We aimed to prospect...

journal_title：Pediatric blood & cancer

authors： Sartori MT,Cesaro S,Peruzzo M,Messina C,Saggiorato G,Calore E,Pillon M,Varotto S,Spiezia L,Cella G

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The identification of tissue-specific differentially methylated regions (tDMRs) is key to our understanding of mammalian development. Research has indicated that tDMRs are aberrantly methylated in cancer and may affect the oncogenic process. PROCEDURE:We used the MassARRAY EpiTYPER system to determine the q...

journal_title：Pediatric blood & cancer

authors： Sugito K,Kawashima H,Uekusa S,Yoshizawa S,Hoshi R,Furuya T,Kaneda H,Hosoda T,Masuko T,Ohashi K,Ikeda T,Koshinaga T,Fujiwara K,Igarashi J,Ghosh S,Held WA,Nagase H

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The objective of this report was to estimate long-term outcome and prognostic factors in children and adolescents with osteosarcoma. A large group of osteosarcoma patients were analyzed at our national oncology center. PROCEDURE:To evaluate the efficacy of surgery and multiagent chemotherapy for treating os...

journal_title：Pediatric blood & cancer

authors： Hegyi M,Semsei AF,Jakab Z,Antal I,Kiss J,Szendroi M,Csoka M,Kovacs G

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Pediatric cancer-induced financial burden is source of stress for parents, particularly mothers, single parents, and parents with lower incomes. This financial burden has been linked to poorer family quality of life (QOL) in terms of new onset material hardships, and could also affect individual QOL in terms...

journal_title：Pediatric blood & cancer

authors： Santacroce SJ,Kneipp SM

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:Current guidelines recommend high-priority treatment of severe sickle cell disease (SCD) pain with opioids; however, patients with SCD have historically been undertreated. We used mixed methods to assess pediatric residents' perceptions toward opioid use in SCD pain management. METHODS:We distributed a surve...

journal_title：Pediatric blood & cancer

authors： Fearon A,Marsh A,Kim J,Treadwell M

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:A National Thalassemia Screening Program was adopted in Taiwan in 1993. This report examined that program's results and impact. METHODS:Patients with beta-thalassemia major born between 1994 and 2003 were recruited through the help of all thalassemia clinics in Taiwan. A structured questionnaire was designed...

journal_title：Pediatric blood & cancer

authors： Chern JP,Lin KH,Lu MY,Lin DT,Jou ST,Yang YL,Chang HH,Su S,Lin KS

更新日期：2008-01-01 00:00:00

abstract：:A male patient diagnosed with severe congenital protein C (PC) deficiency during the neonatal period was treated with long-term warfarin but frequently developed purpura fulminans and bleeding. At four years of age, edoxaban was initiated (direct oral anticoagulant [DOAC]). His d-dimer and fibrin/fibrinogen degradatio...

journal_title：Pediatric blood & cancer

authors： Watanabe K,Arakawa Y,Yanagi M,Isobe K,Mori M,Koh K

更新日期：2019-06-01 00:00:00