Abstract:
:The purpose of this study was to describe the prevalence of total joint arthroplasty (TJA) in Japanese rheumatoid arthritis (RA) patients undergoing conventional drug treatment in a large observational cohort in Japan. A total of 5,177 RA patients were studied for the prevalence of TJA, who were enrolled in the NinJa database during the fiscal year of 2006. The cases of 2,695 RA patients with more than ten years of disease duration were extracted and subjected to further analysis. The prevalence of TJA increased in accordance with the disease duration, and the prevalence was markedly increased after ten years. Among the 2,695 patients with more than ten years of disease duration, 1,431 TJAs were performed in 645 (24.6%) patients. The patients with TJA had higher disease activity than those without TJA. In this cross-sectional study, TJAs were performed in approximately a quarter of the Japanese RA patients with more than ten years of disease duration. The result showed that patients with higher disease activity required TJA.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Nishino J,Tanaka S,Matsui T,Mori T,Nishimura K,Eto Y,Kaneko A,Saisho K,Yasuda M,Chiba N,Yoshinaga Y,Saeki Y,Seki A,Tohma Sdoi
10.1007/s10165-009-0163-3subject
Has Abstractpub_date
2009-01-01 00:00:00pages
260-4issue
3eissn
1439-7595issn
1439-7609journal_volume
19pub_type
杂志文章abstract:OBJECTIVES:The objective of this study is to evaluate the efficacy and safety of long-term (64 weeks; 52-week extension of a 12-week study) baricitinib treatment in Japanese patients with active rheumatoid arthritis (RA) despite methotrexate therapy. METHODS:Patients (N = 145) with active RA were randomized to placebo...
journal_title:Modern rheumatology
pub_type: 杂志文章,随机对照试验
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更新日期:2018-01-01 00:00:00
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更新日期:2011-12-01 00:00:00
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更新日期:2015-01-01 00:00:00
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更新日期:2014-07-01 00:00:00