Evidence that increased 5-HT release evokes region-specific effects on blood-oxygenation level-dependent functional magnetic resonance imaging responses in the rat brain.

abstract：:Fluctuations in the endogenous levels of kynurenic acid (KYNA), a potent alpha7 nicotinic and NMDA receptor antagonist, affect extracellular dopamine (DA) concentrations in the rat brain. Moreover, reductions in KYNA levels increase the vulnerability of striatal neurons to NMDA receptor-mediated excitotoxic insults. W...

journal_title：Neuroscience

authors： Amori L,Wu HQ,Marinozzi M,Pellicciari R,Guidetti P,Schwarcz R

更新日期：2009-03-03 00:00:00

abstract：:A salient feature of the developing brain is that spontaneous oscillations (SOs) and waves may influence the emergence of synaptic connections. While GABA produces depolarization and may support SOs in the neurons of developing rodents, it elicits hyperpolarization and diminishes SOs in developing gerbil auditory cort...

journal_title：Neuroscience

authors： Kotak VC,Péndola LM,Rodríguez-Contreras A

更新日期：2012-12-13 00:00:00

abstract：:Cocaine-induced behavioral sensitization is a complex phenomenon involving a number of neuromodulator and neurotransmitter systems. To specifically investigate the role of the micro opioid receptor (MOR) in cocaine-induced behavioral sensitization in mice, both genetic and pharmacological approaches were undertaken. M...

journal_title：Neuroscience

authors： Hummel M,Ansonoff MA,Pintar JE,Unterwald EM

更新日期：2004-01-01 00:00:00

abstract：:Women have greater temporal summation of experimental pain stimuli and also have a higher propensity for developing chronic visceral pain conditions. Sex hormone-mediated regulation of N-methyl-d-aspartic acid receptors (NMDARs) in nociceptive pathways is a plausible mechanism that may underlie these phenomena. The ai...

journal_title：Neuroscience

authors： McRoberts JA,Li J,Ennes HS,Mayer EA

更新日期：2007-09-21 00:00:00

abstract：INTRODUCTION:Electrophysiological responses to auditory stimuli have provided a useful means of elucidating mechanisms and evaluating treatments in psychiatric disorders. Deficits in gating during paired-click tasks and lack of mismatch negativity following deviant stimuli have been well characterized in patients with ...

journal_title：Neuroscience

authors： Ehrlichman RS,Gandal MJ,Maxwell CR,Lazarewicz MT,Finkel LH,Contreras D,Turetsky BI,Siegel SJ

更新日期：2009-01-23 00:00:00

abstract：:Environmental enrichment of laboratory animals leads to multi-faceted changes to physiology, health and disease prognosis. An important and under-appreciated factor in enhancing cognition through environmental manipulation may be improved basic sensory function. Previous studies have highlighted changes in cortical se...

journal_title：Neuroscience

authors： Devonshire IM,Dommett EJ,Grandy TH,Halliday AC,Greenfield SA

更新日期：2010-10-13 00:00:00

abstract：:When human divers or experimental animals are exposed to high pressure, they develop the high-pressure neurological syndrome which is characterized by electroencephalographic changes, and behavioral disturbances. Recently, neurochemical disorders such as a pressure-induced increase in dopamine release have been demons...

journal_title：Neuroscience

authors： Abraini JH,Fechtali T,Rostain JC

更新日期：1992-09-01 00:00:00

abstract：:Steroid hormones, especially estradiol, facilitate reproductive behaviors in male and female rodents and birds. In green anole lizards estradiol facilitates receptivity in females but, unlike in some other species, is not the activating hormone for courtship and copulatory behavior in males. Instead, testicular androg...

journal_title：Neuroscience

authors： Beck LA,Wade J

更新日期：2009-05-19 00:00:00

abstract：:The effects of Ricinus toxin on the neurons of the ciliary ganglia were investigated in the quail. The neuronal death and the morphological alterations of the ganglionic cells were assessed following injection of the toxin in the anterior chamber of the eye or after application of the toxin on the postganglionic nerve...

journal_title：Neuroscience

authors： Ciofi Luzzatto A,De Stefano ME,Guidolin D,Paggi P,Toschi G

更新日期：1991-01-01 00:00:00

abstract：:The laminar binding distribution of three nicotinic receptor agonists, [3H](-)nicotine, [3H]cytisine, and [3H]epibatidine, and their relation to the [3H]vesamicol binding, which is known to represent the vesicular acetylcholine transport sites, was performed employing in vitro autoradiography on the medial temporal co...

journal_title：Neuroscience

authors： Sihver W,Gillberg PG,Svensson AL,Nordberg A

更新日期：1999-01-01 00:00:00

abstract：:Coordinated activity in different sets of widely-projecting neurochemical systems characterize waking (W) and sleep (S). How and when this coordination is achieved during development is not known. We used embryos and newborns of a precocial bird species (chickens) to assess developmental activation in different neuroc...

journal_title：Neuroscience

authors： Chan A,Li S,Lee AR,Leung J,Yip A,Bird J,Godden KE,Martinez-Gonzalez D,Rattenborg NC,Balaban E,Pompeiano M

更新日期：2016-12-17 00:00:00

abstract：:Ovarian hormones regulate pyramidal cell synapse formation and excitability and interneuronal GABAergic tone in the CA1 region of the adult female rat hippocampus. The role of 17beta-estradiol in these effects is complex and appears to involve a subset of hippocampal interneurons, which express different calcium-bindi...

journal_title：Neuroscience

authors： Nakamura NH,McEwen BS

更新日期：2005-01-01 00:00:00

abstract：:Perceiving the sensory consequences of our actions with a delay alters the interpretation of these afferent signals and impacts motor learning. For reaching movements, delayed visual feedback of hand position reduces the rate and extent of visuomotor adaptation, but substantial adaptation still occurs. Moreover, the d...

journal_title：Neuroscience

authors： Shiller DM,Mitsuya T,Max L

更新日期：2020-10-15 00:00:00

abstract：:Cholesterol is an essential substance for maintaining normal structure and function of the brain. But unfortunately, a long-term high-cholesterol diet can lead to a variety of pathological changes of the brain such as β-amyloid (Aβ) accumulation, Tau hyperphosphorylation, reactive gliosis, neuroinflammation, neuronal ...

journal_title：Neuroscience

authors： Chen YL,Wang LM,Chen Y,Gao JY,Marshall C,Cai ZY,Hu G,Xiao M

更新日期：2016-03-01 00:00:00

abstract：:The heme oxygenase (HO) enzyme system has been shown to participate in nociceptive signaling in a number of different models of pain. In these experiments we investigated the role of the HO type 2 (HO-2) isozyme in tolerance to the analgesic effects of morphine, and the hyperalgesia and allodynia which are measurable ...

journal_title：Neuroscience

authors： Liang D,Li X,Lighthall G,Clark JD

更新日期：2003-01-01 00:00:00

abstract：:In the European rabbit (Oryctolagus cuniculus) nursing acts as a strong non-photic synchronizer of circadian rhythmicity in the newborn young. Rabbits only nurse for a few minutes once every 24 h and previous studies have shown that the pups, blind at birth, display endogenous circadian rhythms in behavior and physiol...

journal_title：Neuroscience

authors： Caldelas I,Tejadilla D,González B,Montúfar R,Hudson R

更新日期：2007-01-19 00:00:00

abstract：:The effects of intrathecal administration of neurokinin A, substance P and [Tyr5, D-Trp6,8,9 Arg10]neurokinin A-(4-10) (Men 10207), a specific NK-2 receptor antagonist, on the spinal nociceptive flexor reflex were studied in decerebrate, spinalized, unanesthetized rats. Intrathecal neurokinin A and substance P facilit...

journal_title：Neuroscience

authors： Xu XJ,Maggi CA,Wiesenfeld-Hallin Z

更新日期：1991-01-01 00:00:00

abstract：:Rats were trained in a specially designed apparatus to detect brief, unpredictable visual stimuli presented to either side of the head. In one condition, rats reported the detection of the visual stimulus by removing their heads from a central location and responding in one of two adjacent side-holes where the visual ...

journal_title：Neuroscience

authors： Carli M,Jones GH,Robbins TW

更新日期：1989-01-01 00:00:00

abstract：:Hypofunction of the N-methyl-D-aspartic acid receptor (NMDAr) has been considered to play a crucial role in the pathophysiology of schizophrenia. In rodent electroencephalogram (EEG) studies, non-competitive NMDAr antagonists have been reported to produce aberrant basal gamma band oscillation (GBO), as observed in sch...

journal_title：Neuroscience

authors： Hiyoshi T,Kambe D,Karasawa J,Chaki S

更新日期：2014-11-07 00:00:00

abstract：:The rat pineal gland is an attractive system for studies on the capacity of neural systems to recover following partial injury, allowing both for the creation of precise subtotal lesions and for the measurement of recovery of function at the cellular level. The pineal gland receives overlapping sympathetic innervation...

journal_title：Neuroscience

authors： Kuchel GA,Sherman RL,Zigmond RE

更新日期：1990-01-01 00:00:00

abstract：:The pharmacological features of putative nicotinic acetylcholine receptor sites involved in the release of [3H]noradrenaline were assessed in rat hippocampus. The effect of nicotinic agonists to induce [3H]noradrenaline release was examined in superfused slices. The nicotinic agonists (-)-epibatidine, (+)-anatoxin-a, ...

journal_title：Neuroscience

authors： Sershen H,Balla A,Lajtha A,Vizi ES

更新日期：1997-03-01 00:00:00

abstract：:It is well established that multisensory integration is a functional characteristic of the superior colliculus that disambiguates external stimuli and therefore reduces the reaction times toward simple audiovisual targets in space. However, in a condition where a complex audiovisual stimulus is used, such as the optic...

journal_title：Neuroscience

authors： Costa M,Piché M,Lepore F,Guillemot JP

更新日期：2016-04-21 00:00:00

abstract：:Cervical or high thoracic spinal cord injury often results in autonomic dysreflexia, a condition characterized by exaggerated spinal reflexes and episodic hypertension, that may be caused by reorganization of synapses on sympathetic preganglionic neurons after loss of supraspinal input. To assess remodelling of synapt...

journal_title：Neuroscience

authors： Weaver LC,Cassam AK,Krassioukov AV,Llewellyn-Smith IJ

更新日期：1997-11-01 00:00:00

abstract：:The present study was designed to investigate the roles of different subtypes of opioid receptors in ventrolateral orbital cortex (VLO) opioid-evoked antinociception in formalin test by using an automatic detection system for recording the nociceptive behavior (agitation) and a manual method for detecting the duration...

journal_title：Neuroscience

authors： Xie YF,Wang J,Huo FQ,Jia H,Tang JS

更新日期：2004-01-01 00:00:00

abstract：:We placed pellets of horseradish peroxidase in the superior colliculus of four macaque monkeys and retrogradely labelled the retinal ganglion cells of both eyes. The ratio of labelled cells in the contralateral nasal retina and the ipsilateral temporal retina was no different from the ratio found after implants in the...

journal_title：Neuroscience

authors： Williams C,Azzopardi P,Cowey A

更新日期：1995-03-01 00:00:00

abstract：:How does our mind produce physical, goal-directed action of our body? For about 200years, philosophers and psychologists hypothesized the transformation from mind to body to rely on the anticipation of an action's sensory consequences. Whereas this hypothesis received tremendous support from behavioral experiments, th...

journal_title：Neuroscience

authors： Pfister R,Melcher T,Kiesel A,Dechent P,Gruber O

更新日期：2014-02-14 00:00:00

abstract：:Analyses of scalp-recorded sleep spindles have demonstrated topographically distinct slow and fast spindle waves. In the present paper, the electrical activity in the brain corresponding to different types of sleep spindles was estimated by means of low-resolution electromagnetic tomography. In its new implementation,...

journal_title：Neuroscience

authors： Anderer P,Klösch G,Gruber G,Trenker E,Pascual-Marqui RD,Zeitlhofer J,Barbanoj MJ,Rappelsberger P,Saletu B

更新日期：2001-01-01 00:00:00

abstract：:Approximately 50% of patients who survived after aneurysmal subarachnoid hemorrhage (SAH) have cognitive or neurobehavioral dysfunction. The mechanisms are not known. NR2B, one of the subunits of N-methyl-d-aspartate (NMDA) receptors, has been proved to be an important factor for synapse function and behavior cognitio...

journal_title：Neuroscience

authors： Chen G,Li Q,Feng D,Hu T,Fang Q,Wang Z

更新日期：2013-02-12 00:00:00

abstract：:Mutations in γ-aminobutyric acid A receptor (GABAA) subunits and sodium channel genes, especially GABRG2 and SCN1A, have been reported to be associated with febrile seizures (FS) and genetic epilepsy with febrile seizures plus (GEFS+). GEFS+ is a well-known family of epileptic syndrome with autosomal dominant inherita...

journal_title：Neuroscience

authors： Li X,Guo S,Liu K,Zhang C,Chang H,Yang W,Rong S,Hu Q,Cui J,Wang F,Sun T

更新日期：2020-07-01 00:00:00

abstract：:Huntington's disease (HD) is a severe genetically inherited neurodegenerative disorder. Patients present with three principal phenotypes of motor symptoms: choreatic, hypokinetic-rigid and mixed. The Q175 mouse model of disease offers an opportunity to investigate the cellular basis of the hypokinetic-rigid form of HD...

journal_title：Neuroscience

authors： Rothe T,Deliano M,Wójtowicz AM,Dvorzhak A,Harnack D,Paul S,Vagner T,Melnick I,Stark H,Grantyn R

更新日期：2015-12-17 00:00:00