Abstract：
:Invasive candidiasis (IC) includes candidemia, disseminated candidiasis with deep organ involvement, endocarditis and meningitis. IC has an attributable mortality of 40% to 50% and is increasingly reported in intensive care units (ICUs). Candida albicans and non-albicans strains are both responsible for infections in ICUs, where empirical and targeted treatments especially need to be initially appropriate. This review synthesizes the most recent guidelines for IC and candidemia from an ICU perspective. Essentially, patients who have been previously exposed to azoles have a higher probability of being infected by azole-resistant or non-albicans strains. Infection site, illness severity, neutropenia, hemodynamic status, organ failure and concomitant drug treatments are host-related factors that influence the choice of anti-fungal treatment. In general, echinocandins are currently favored for empiric treatment of candidemia, especially in critically ill patients or those with previous azole exposure. Pharmacokinetic properties and side effects suggest that polyenes should be avoided in patients with renal failure, and that echinocandins and azoles should be avoided in patients with severe hepatic dysfunction.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
De Rosa FG,Garazzino S,Pasero D,Di Perri G,Ranieri VMsubject
Has Abstractpub_date
2009-07-01 00:00:00pages
453-8issue
7-8eissn
0375-9393issn
1827-1596pii
R02085421journal_volume
75pub_type
杂志文章,评审abstract：BACKGROUND:Aim of the study was to validate commonly used bedside right-ventricular (RV) impedance parameters, which are utilized in determining heart-lung interactions during mechanical ventilation. METHODS:Fifteen pigs were equally assigned to either an open or a closed pericardium group. In all animals, an inflatab...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-11-01 00:00:00
abstract：:The surgical treatment of cervico-medullary traumas is indicated, in unstable lesions, in large lesions of the mobile rachidic segment in the presence of neurological complications or following worsening of prior neurological symptomatology. The purpose of the operation is at least three-fold: to obtain alignment of v...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the cerebral blood flow parameters assessed by transcranial Doppler during aortic cross-clamping and unclamping in patients undergoing abdominal aortic aneurysmectomy. METHODS:Invasive intraoperative monitoring of mean arterial pressure (MAP) and PaCO2, and right middle cerebral artery (RMCA) mon...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:Arginine vasopressin (AVP) and its synthetic, long-acting analog terlipressin (TP) are potent alternative vasoconstrictors in the treatment of septic patients with catecholamine-refractive vasodilatatory shock. The results from one large randomized clinical trial suggest that AVP plus norepinephrine (NE) infusion is a...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2010-10-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：10.23736/S0375-9393.19.13597-3
更新日期：2019-02-01 00:00:00
abstract：:Extracorporeal membrane oxygenation (ECMO) can be used to preserve or enhance systemic oxygen delivery in patients with refractory cardiac or respiratory failure. Although widely accepted as a standard of care for many indications in children and for adult cardiogenic shock, ECMO for adult respiratory failure is more ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：INTRODUCTION:Recent data found that perioperative goal directed therapy (GDT) was effective only in higher control mortality rates (>20%) with a relatively high heterogeneity that limited the strength of evidence. The aim of the present meta-analysis was to clearly understand which high risk patients may benefit of GDT...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,meta分析
doi：
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Data from patient questionnaires reveal that the intensity of postoperative pain is widely underestimated. Insufficient pain control may contribute to impaired short- and long-term outcome. Preoperative administration of methadone might potentially improve postoperative pain control due to its long pharmacol...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：10.23736/S0375-9393.19.13136-7
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:General anesthesia utilizing inhalational agents without intravenous (IV) access for minor procedures is controversial. Eliminating IV access increases efficiency and patient satisfaction; however, the ability to introduce rapid acting medications into the circulation during an unanticipated emergency become...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.17.11565-8
更新日期：2017-07-01 00:00:00
abstract：:Pulmonary gas exchange is regularly impaired during general anaesthesia with mechanical ventilation. This results in decreased oxygenation of blood. Major causes are collapse of lung tissue (atelectasis) and airway closure. Collapsed lung tissue is present in 90% of all subjects, both during spontaneous breathing and ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2002-05-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 评论,信件
doi：10.23736/S0375-9393.19.13835-7
更新日期：2019-10-01 00:00:00
abstract：:We studied 10 consecutive, sedated and paralyzed patients with Acute Respiratory Distress Syndrome (ARDS). The entire study lasted 4 hours, divided in 3 periods: 2 hours of recommended ventilation [lung protective strategy, LPS, i.e., ventilation with low tidal volume (< 8 mL/kg), limiting the plateau at 35 cm H2O, to...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1999-05-01 00:00:00
abstract：BACKGROUND:The use of second generation supraglottic airway devices is recommended for airway rescue in failed tracheal intubation. This study was performed to compare the clinical performance of the i-gel™ with that of the AuraGain™ in patients with simulated cervical immobilization. METHODS:We conducted a prospectiv...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.20.14237-8
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Devices that limit microaspiration through the cuffs of endotracheal tubes could help prevent ventilator-associated pneumonia (VAP). The amount of tracheal microaspirations could be a relevant study endpoint. The aim of our study was to assess whether amylase measured in tracheal secretions constituted a rel...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：:The improvement in the success of solid organ transplantation over the past decades is remarkable and well documented. It is now a well-accepted treatment modality for patients with end-stage organ disease. Within the field of transplantation, abdominal organ transplantation is significantly more common than thoracic ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:The aim was to investigate whether tramadol had toxic effect on cerebral neurons and/or spinal cord neurons when it was administered into the cerebrospinal fluid. Due to lipid peroxidation (LPO) and myeloperoxidation (MPO) levels are not specific predictors of neuronal damage, these biochemical markers of ti...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:When patients are incompetent, advance directives (AD) can help physicians take crucial medical decisions. However, prevalence remains low. The objective was to investigate physicians' perspectives and attitudes towards AD in order to determine potential targets for improvement. METHODS:Observational study ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:We prospectively evaluated the effect of insertion angle on the visibility of echogenic and nonechogenic needles in phantoms and in axillary nerve blocks in patients. METHODS:Conventional and echogenic needles were studied in phantoms at insertion angles of 0-30°, 30-45°, and ≥ 45°. Operators rated comfort ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:The majority of intensive care physicians recognize the clinical significance of intra-abdominal hypertension on the outcome of critically ill patients. Abdominal compartment syndrome (ACS) is defined as an intra-abdominal pressure (IAP) >20 mmHg with ongoing organ failure. However, there is no consensus reg...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the value of serial quantitative (QC) and non-quantitative (NQC) endotracheal aspirate (ETA) surveillance cultures in predicting the causative pathogen of ventilator associated pneumonia (VAP) in patients receiving antibiotic therapy and the factors associated with th...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:In this study, the level and the variation of a number of hormone and metabolic parameters during brain death treatment in potential organ donors have been monitored. METHODS:Thirty-nine consecutive brain-dead patients were enrolled in 3 Intensive Care Units of Regional Hospitals of the North of Italy. All ...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 信件
doi：10.23736/S0375-9393.19.13457-8
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Evidences supporting the use of ICP monitoring after aneurysmal subarachnoid hemorrhage (aSAH) are limited. The aim of our paper is to examine whether elevated intracranial pressure (ICP) and ICP-derived variables predict mortality and functional outcomes after aSAH. METHODS:A systematic review of the liter...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2016-04-05 00:00:00
abstract：OBJECTIVE:To set up an index for the evaluation of type of interventions and procedures applied a prerequisite for the evaluation of appropriateness of ICU's activity. DESIGN:Observation prospective study. PATIENTS:2507 patients out of the 5030 enrolled in the cohort study. MEASUREMENTS:A cross-sectional assessment ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：BACKGROUND:Few studies have investigated the incidence of pulmonary anaerobes in a specific population in surgical Intensive Care Unit (ICU). The objective of this work was to determine the incidence of anaerobes in surgical ICU patients with suspected pneumonia. METHODS:This was a prospective observational, single-ce...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-10-01 00:00:00
abstract：:The term "chronic" is often used in daily clinical practice to indicate a type of pain that lasts over time and is accompanied by diagnostic and therapeutic difficulties. The common feeling is that in this category are actually collected many different clinical cases with the unique characteristic that the pain lasts ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2012-06-01 00:00:00
abstract：AIM:High-flow-oxygen-therapy is provided by various techniques and patient interfaces, resulting in various inspired-fraction of oxygen (FiO2) and airway-pressure levels. However, tracheal measurements have never been performed. METHODS:Three oxygen-delivery-devices were evaluated: 1) standard-high-flow-oxygen-facemas...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 信件
doi：10.23736/S0375-9393.18.12938-5
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Coronary artery bypass graft surgery with cardiopulmonary bypass induces a systemic inflammatory response. However, when thoracic epidural anaesthesia is administered as part of a combined anesthetic technique, the stress response associated with the cardiopulmonary bypass (CPB) may be attenuated. METHODS:T...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of two cardiac output measurement methods based on a modified Fick equation, that calculate the O2 consumption (VO2) dividing the CO2 production (VCO2) by a fixed respiratory quotient (RQ). DESIGN:Comparative study. SETTING:One 5 beds general intensive care unit in a 500 beds g...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-05-01 00:00:00
