Abstract：
:Arginine vasopressin (AVP) and its synthetic, long-acting analog terlipressin (TP) are potent alternative vasoconstrictors in the treatment of septic patients with catecholamine-refractive vasodilatatory shock. The results from one large randomized clinical trial suggest that AVP plus norepinephrine (NE) infusion is as safe and effective as treatment with NE alone in patients with septic shock. Because the desired effects of vasopressin analogs are basically related to their vasopressinergic effects via the V1a receptor, more selective V1 agonists, such as TP, may be more potent in reversing sepsis-related arterial hypotension. In this regard, recent evidence from small-scale studies suggests that continuous low-dose infusion rather than intermittent bolus injection of TP is associated with fewer side effects, such as depression of cardiac output and rebound arterial hypotension. However, because clinical data on the administration of TP in patients with sepsis are limited, it should not currently be used beyond the scope of controlled trials. The optimal time point for the initiation of therapy with vasopressin analogs has yet to be determined. While AVP and TP are commonly used as last-resort therapies in severe septic shock, some evidence supports the initiation of treatment in a less severe state of the disease.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
Kampmeier TG,Rehberg S,Westphal M,Lange Msubject
Has Abstractpub_date
2010-10-01 00:00:00pages
844-50issue
10eissn
0375-9393issn
1827-1596pii
R02106211journal_volume
76pub_type
杂志文章,评审abstract：OBJECTIVE:To evaluate efficacy and tolerability of enoximone, a phosphodiesterase inhibitor, in the treatment of cardiogenic shock. DESIGN:A prospective non randomized, non comparative study. SETTING:A general intensive care unit of a university hospital. PATIENTS:Six patients with cardiogenic shock (cardiac index <...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:The analysis of the arterial pulse contour obtained by means of a non-invasive device (Finapres) seems to be an ideal method to measure cardiac output (CO). An individual calibration factor (Z) dimensionally equal to aortic impedence is the necessary pre-requisite to calculate CO by pulse contour analysis. T...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:Intranasal dexmedetomidine, although still off-label, recently boasted an increasing consensus for different uses, namely, in diagnostic non-painful procedures, in painful procedures and in surgical premedication. However, at present, there is no consensus regarding indications, dosage and timing for administration. T...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：10.23736/S0375-9393.19.13820-5
更新日期：2019-12-01 00:00:00
abstract：:TOSS, together with severity of illness (SAPS) and intensity of processes (TISS), has been determined in 941 patients on the 9th day of ICU stay, to ascertain the validity of TOSS in the calculation of the nurse/patient ratio, not only at the time of admission to ICU but also during the stay. The mean values of all in...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,多中心研究
doi：
更新日期：1992-12-01 00:00:00
abstract：:Known for two centuries, positive pressure non invasive mechanical ventilation (VMNPP) has been widely applied in acute respiratory failure (IRA) only in the last ten years. The fact that VMNPP is able to improve gas exchange by avoiding endotracheal intubation and its complications is the most attractive aspect in bo...
journal_title：Minerva anestesiologica
pub_type： 历史文章,杂志文章,评审
doi：
更新日期：2000-10-01 00:00:00
abstract：:A double blind comparison between morphine and buprenorphine was performed in 20 patients using a new demand and continuous infusion analgesic system to provide analgesia after cesarean section. The patients were randomized in two equal groups to receive either morphine 1 mg/h or buprenorphine 0.03 mg/h. The PCA syste...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Pharyngolaryngeal discomfort is a significant complication following the use of laryngeal mask airway (LMA). The present study aimed to investigate the relation of LMA cuff pressure and the occurrence of pharyngolaryngeal discomfort during spontaneous ventilation (SV), pressure support (PSV) and pressure con...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2014-05-01 00:00:00
abstract：:The detection of tissue hypoxia and its correction is one of the aim of the hemodynamic monitoring. Classical hemodynamic variable often fail to achieve this goal. Lactate measurements may be a good indicator of tissue hypoxia. Selected review of the articles on lactate in critically ill patients. Tissue hypoxia is as...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2003-04-01 00:00:00
abstract：:The Authors present a retrospective review that compares general anesthesia with regional anesthesia performed during carotid endarterectomy surgery. The study includes 147 procedures, performed on 144 patients: 76 had general anesthesia and 71 had regional anesthesia. After emphasizing the importance of conscience pr...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：:Arrhythmias are common in hospitalized patients and during surgery. We present a case of positional atrial arrhythmia related to a peripherally inserted central catheter (PICC). There are other documented case reports of ventricular tachycardia precipitated by body position changes with a PICC. The immediate correctio...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2009-07-01 00:00:00
abstract：UNLABELLED:The aim of this study is the comparison between the use of bupivacaine alone and a mixture of bupivacaine, mepivacaine and hyaluronidase in both retrobulbar and peribulbar blockades for eye surgery. Three hundred ninety-nine consecutive adult patients scheduled for cataract surgery with regional anaesthesia ...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1999-11-01 00:00:00
abstract：:Pulmonary complications are a source of greater postoperative morbidity and mortality and longer hospital stays. Although many factors have been implicated as predictors, few models have been developed with the rigorous methodology required for clinically useful tools. In this article we attempt to describe what to lo...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-03-01 00:00:00
abstract：:Two large phase-III prospective, multicenter, controlled, double-blind, randomized clinical trials (the PROTECT III study; the SYNAPSE study) evaluated the effectiveness of an early administration of progesterone in patients with moderate to severe traumatic brain injury (TBI). In the PROTECT III Trial, patients were ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-04-01 00:00:00
abstract：:The authors report the results of two clinical studies on postoperative pain relief with PCA. In the first clinical study 44 patients, undergoing gynecologic surgery, were assigned at random to two groups. The first was treated by PCA (infusor Baxter) with morphine i.v. (basal bolus 0.05 mg/kg, loading doses 1 mg ever...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1993-10-01 00:00:00
abstract：INTRODUCTION:Although many drugs have been studied to prevent postoperative shivering, their comparative effectiveness is unknown. We attempted to assess the comparative effectiveness of the pharmacologic strategies to prevent shivering after surgery including intravenous (IV) and intrathecal (IT) meperidine, IV and IT...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,meta分析,评审
doi：10.23736/S0375-9393.18.12813-6
更新日期：2019-01-01 00:00:00
abstract：:In 8 patients who underwent abdominal surgery for non-neoplastic reasons, we have evaluated some parameters of renal function (PRP, NaU, GFR and diuresis) plasma levels of PRA and ADH and urinary prostaglandins PGE2 and 6-keto-PGF1 alpha. In 4 patients we found that surgery per se was associated with enhancements of P...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：BACKGROUND:We prospectively evaluated the effect of insertion angle on the visibility of echogenic and nonechogenic needles in phantoms and in axillary nerve blocks in patients. METHODS:Conventional and echogenic needles were studied in phantoms at insertion angles of 0-30°, 30-45°, and ≥ 45°. Operators rated comfort ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2015-04-01 00:00:00
abstract：INTRODUCTION AND AIMS:Thromboembolic disease can, in a large number of cases, be prevented in patients undergoing major surgery by using low molecular weight heparin (LMWH). These molecules extracted from standard heparin using a variety of cleavage methods possess different physical and chemical characteristics. The a...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Data concerning antibiotic therapy in italian ICUs are presented. These data were not directly measured: they have been derived from a previous study on costs of intensive care treatments. 78% of 1065 patients received antibiotic therapy. Empirical therapy was started in 82% of septic patients. 93% of septic patients ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:Tonomitor NG tube was positioned in the stomach of 11 critical ill patients during their stay in ICU and 48 measurements of intramucosal pH (pHi) have been performed. In 7 patients haemodynamic measurement were performed in concomitance with each pHi measure. The Authors looked for statistical relations between pHi an...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-11-01 00:00:00
abstract：:The nonsteroidal anti-inflammatory drugs (NSAIDs) cover a wide range of selectivity, from the nonselective cyclooxygenase (COX) inhibitors to the preferential COX-2, and the newest coxibs, selective COX-2, with 1000-fold selectivities for COX-2. Coxibs belong to the distinct classes of sulphonamides, methylsulphones, ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:To test validity, safety, costs and healing-outcome of surgical minitracheotomy after cannula removing. METHODS: DESIGN:Opened, perspective. Site: Polyvalent ICU. PATIENTS:40 patients underwent surgical minitracheotomy, in a year. Traditional surgical technique was adopted. Minitracheotomy was performed b...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:Trapeziectomy is one of the most painful procedures in ambulatory surgery. This prospective randomized trial aimed to compare postoperative pain control using distal peripheral nerve blocks (dPNB) with a low concentration of a long-acting local anesthetic versus conventional systemic analgesia. METHODS:Fift...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：10.23736/S0375-9393.18.12291-7
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Evidences supporting the use of ICP monitoring after aneurysmal subarachnoid hemorrhage (aSAH) are limited. The aim of our paper is to examine whether elevated intracranial pressure (ICP) and ICP-derived variables predict mortality and functional outcomes after aSAH. METHODS:A systematic review of the liter...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2016-04-05 00:00:00
abstract：BACKGROUND:This study aimed to determine the accuracy of commonly used preoperative difficult airway indices as predictors of difficult mask ventilation (DMV) in obese patients (BMI >30 kg/m2). METHODS:In 309 consecutive obese patients undergoing general surgery, the modified Mallampati test, patient's Height/Thyromen...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-02-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 评论,社论
doi：10.23736/S0375-9393.18.13260-3
更新日期：2019-04-01 00:00:00
abstract：:Inhalation agents represent a basic drug used in modern balanced anesthesia. In the present review, the pharmacokinetics, effectiveness and clinical effects of inhalation agents on different systems are discussed. Data concerning the metabolism and related toxicity of halogenated agents is reviewed, with particular re...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Oral premedication is common practice in paediatric anaesthesia. The aim of this study was to assess the quality of premedication using oral ketamine, with midazolam. METHODS:Clinical randomized and blind-study on 120 patients, aged between 2 and 6 years, listed for minor surgery. Patients were divided in t...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2002-07-01 00:00:00
abstract：:An account is given of the employment of althesin as an induction and maintenance anaesthetic. It is free of the drawbacks observed with thiopentone induction, and has negligible haemodynamic and respiratory effects. Its association with leptophen permitted excellent analgesia at minimal leptophen doses, without secon...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-02-01 00:00:00
abstract：:Stroke is a devastating complication that is difficult to diagnose in the perioperative setting because of the effects of anesthetic and analgesic agents. Lingering anesthesia effects hinder clinicians in identifying stroke symptoms, frequently resulting in a delay in diagnosis and treatment and in unfavorable outcome...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.17.11976-0
更新日期：2017-11-01 00:00:00
