Abstract：
INTRODUCTION AND AIMS:Thromboembolic disease can, in a large number of cases, be prevented in patients undergoing major surgery by using low molecular weight heparin (LMWH). These molecules extracted from standard heparin using a variety of cleavage methods possess different physical and chemical characteristics. The aim of this study was to compare two LMWH in the prevention of thromboembolism and in terms of safety. METHODS:Thirty patients of both sexes were admitted to the study and underwent major abdominal surgery. Fifteen patients were treated with dalteparin sodium, 2500 IU, and fifteen with nadroparin calcium, 3075 IU. Subcutaneous administration was commenced two hours prior to surgery and continued for at least five days after the operation until the complete mobilisation of the patient. Six blood samples were taken from each patient in order to assay: aPTT, heparin, X factor, Quick time, ATIII, platelets and hemoglobin. Intraoperative bleeding and drainage were recorded for each patient. RESULTS:The group treated with nadroparin showed a significant reduction in hemoglobin, correlated with greater blood loss (p < 0.05) compared to the group treated with dalteparin. CONCLUSIONS:Both nadroparin and dalteparin showed good anti-Xa activity and safety, but although they possess the same pharmacodynamic characteristics, they should not be regarded as equal or interchangeable.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
Mabilia MA,Minicucci S,Pettiti G,Tamponi G,Bogli Fsubject
Has Abstractpub_date
1996-12-01 00:00:00pages
395-401issue
12eissn
0375-9393issn
1827-1596journal_volume
62pub_type
临床试验,杂志文章abstract：:The Authors present a retrospective review that compares general anesthesia with regional anesthesia performed during carotid endarterectomy surgery. The study includes 147 procedures, performed on 144 patients: 76 had general anesthesia and 71 had regional anesthesia. After emphasizing the importance of conscience pr...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：BACKGROUND:To compare the anaesthetic epidural effects of levobupivacaine plus fentanyl versus bupivacaine plus fentanyl in patients undergoing lower limb surgery. METHODS:A single blind, randomised, prospective, multicentre study was designed to compare both therapies. The study was conducted in 10 tertiary hospitals...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,多中心研究,随机对照试验
doi：
更新日期：2008-07-01 00:00:00
abstract：:Over the last two decades, experimental and clinical data have begun to shape a more discriminating approach to intravascular (IV) fluid infusions in the resuscitation of trauma patients with presumed internal hemorrhage. This approach takes into account the presence of potentially uncontrollable hemorrhage (e.g., dee...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2011-10-01 00:00:00
abstract：:The introduction of use of propofol in the anesthetists' pharmacopoeia has reinvigorated the research for a totally intravenous anaesthesia, for which the Authors propose a diagram. However, in experience related to the supplementary use of N2O, in virtue of its analgesic power, demonstrates yet another utility, permi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:More and more evidence accumulates suggesting that the reversal of the catabolic responses to surgery is associated with better outcome. The potential for anesthesiologists to be involved in altering outcome by simply preserving a normal blood glucose, providing optimal pain control and perioperative feeding is tremen...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-06-01 00:00:00
abstract：:Mechanical ventilation may induce or aggravate lung injury, a phenomenon known as ventilator induced lung injury (VILI). On a macroscopic level, the effects of mechanical stress and strain on lung tissue are well described. Increased tidal volumes may lead to volutrauma, raised airway pressures may cause barotrauma an...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2014-08-01 00:00:00
abstract：:Intravenous administration of 400-600 mg/day potassium canrenoate normalised plasma osmolarity and permitted rapid re-establishment of the metabolic picture in 9/12 patients with hyperosmolarity admitted to a resuscitation department for complex physiopathological pictures. The soundness of the drug in this sense is a...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1979-09-01 00:00:00
abstract：:Regional anaesthesia is useful in day surgery when properly applied. Most commonly used techniques are IVRA, axillary block, local/infiltration plus monitored anaesthesia care. Spinal anaesthesia is also frequently used in DS. Depending on the technique used RA may fasten or prolong discharge when compared to general ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1999-06-01 00:00:00
abstract：BACKGROUND:Data from patient questionnaires reveal that the intensity of postoperative pain is widely underestimated. Insufficient pain control may contribute to impaired short- and long-term outcome. Preoperative administration of methadone might potentially improve postoperative pain control due to its long pharmacol...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：10.23736/S0375-9393.19.13136-7
更新日期：2019-10-01 00:00:00
abstract：:In 8 patients who underwent abdominal surgery for non-neoplastic reasons, we have evaluated some parameters of renal function (PRP, NaU, GFR and diuresis) plasma levels of PRA and ADH and urinary prostaglandins PGE2 and 6-keto-PGF1 alpha. In 4 patients we found that surgery per se was associated with enhancements of P...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:Noninvasive mechanical ventilation (NIV) has become a standard of care in select patients with both hypercapnic and non-hypercapnic acute respiratory failure (ARF). Consequent to the increasing use of NIV, new interfaces of different designs, shapes, sizes, and materials have been proposed for clinical use in recent y...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2012-10-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 信件
doi：10.23736/S0375-9393.18.12938-5
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the incidence of colonization and infection by methicillin-resistant in PICU. DESIGN:Prospective cohort study during 2 years for the surveillance of nosocomial infections. SETTING:Four beds Pediatric Intensive Care Unit. PATIENTS:We studied two-hundred patients with duration of hospitalization ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：AIM:An increased thyroxine requirement has been described in hypothyroid patients who have chronic gastritis as well as in patients who are treated with drugs that modify the acidic environment of the stomach. Patients with acute critical illnesses are generally treated with calorically dense enteral solutions and anta...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:To set up an index for the evaluation of type of interventions and procedures applied a prerequisite for the evaluation of appropriateness of ICU's activity. DESIGN:Observation prospective study. PATIENTS:2507 patients out of the 5030 enrolled in the cohort study. MEASUREMENTS:A cross-sectional assessment ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：BACKGROUND:The effort to decrease hospital stays and to increase operating room efficacy has become an important consideration in the practice of anesthesia. METHODS:Fifty-three patients who underwent shoulder rotator cuff repair in the sitting position were divided into four groups according to the anesthesia techniq...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：:This year, the US Institute of Medicine has estimated that medical errors kill up to 98,000 Americans each year,1 a problem surpassing automobile fatalities. For patients on the medical ward, drug therapy is the primary intervention they are receiving yet medication errors occur in as many as 4% of inpatients.2 Althou...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
abstract：BACKGROUND:The ideal tidal volume (TV) during one-lung ventilation (OLV) remains controversial. High TVs may increase the incidence of postoperative lung injury after thoracic surgery. There is nonetheless little evidence that the use of low TV during OLV will fail to provide adequate arterial oxygenation. We evaluated...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2013-01-01 00:00:00
abstract：:With the first generation of ventilators, it was often necessary to sedate patients to avoid dyssynchrony between patient and ventilator. The standard treatment of patients in need of mechanical ventilation has therefore traditionally included sedation. Modern ventilators are able to simulate the patients breathing ef...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：AIM:The aim of the paper was to examine the attitudes of the health care workers (HCW) of five Italian Hospitals towards intensive supports, in the hypothesis that a large involvement could help to solve the problems of a more adequate management of vital supports. METHODS: DESIGN:Hospital HCWs' attitudes towards car...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:Mechanical ventilation (MV) with positive pressure insufflations of gas into the lung may be required to ensure sufficient oxygenation of blood and elimination of carbon dioxide in acute respiratory failure. Interfacing spontaneous breathing and mechanical ventilation has been used to improve gas exchange and may offe...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-01 00:00:00
abstract：:A randomized, multicenter trial conducted in 32 northern European general intensive care units (ICUs) enrolled some patients with septic shock randomly assigned to receive a red blood cell transfusion when the hemoglobin (Hb) level was ≤7 g/dL ("lower threshold"; N.=502) or ≤9 g/dL ("higher threshold"; N.=496) through...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-09-01 00:00:00
abstract：:A correct assessment of arterial pressure state during SAH is one of most critical issue in neurologic intensive care. It is important to evaluate two different clinical conditions: a) during SAH when the aneurysm is open, b) after aneurysmal clipping or embolization. The authors propose pressure parameters appropriat...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:Prehospital care is a fundamental element for the patient's outcome, in the field of medical and surgical emergencies. There are different strategies about it, defined "scoop and run" and "stay and play". The choice among the different strategies, in our opinion, must be well-suited to the underlying pathophysiology o...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:Multiple patient and clinical characteristics contribute to the variable outcome of spinal anesthesia (SPA). Acute reduction of cerebrospinal fluid (CSF) volume may alter the effect of SPA. The objective of the present study was to test if aspiration of 10 mL CSF immediately prior to SPA is associated with h...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.20.14138-5
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:To assess and record the response to continuous infusion of the phosphodiesterase inhibitor enoximone during weaning from mechanical circulatory support (MCS) and to verify the possibility of success with this indication in pediatric patients. DESIGN:Retrospective study. SETTING:Pediatric cardiac surgery in...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:Even moderate temperature elevations soon acute cerebral damage may markedly worsen initial brain injury. These effects may justify aggressive antipyretic treatment in neurosurgical intensive care unit (NICU). On the basis of a literature survey, it is observed that fever is extraordinarily common in the neurosurgical...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2003-04-01 00:00:00
abstract：:In the last decade, there has been increasing use of the da Vinci® robot surgical system to perform minimally invasive thoracic surgery. The robotic technology can be applied for surgery of the lungs, mediastinum, and esophagus. A number of case reports have been shown steep learning curve, and promising surgical outc...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2014-01-01 00:00:00
abstract：:Humoral immunity (immunoglobulins and C3) as well as nutritional conditions (serum albumin, transferrin) have been investigated in 23 patients in the acute phase after surgery and/or trauma. Immunoglobulin deficiency, well correlated with the severity of trauma, was observed in the most critically ill patients in the ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1981-08-01 00:00:00
abstract：:The detection of tissue hypoxia and its correction is one of the aim of the hemodynamic monitoring. Classical hemodynamic variable often fail to achieve this goal. Lactate measurements may be a good indicator of tissue hypoxia. Selected review of the articles on lactate in critically ill patients. Tissue hypoxia is as...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2003-04-01 00:00:00
