Heliox with inhaled nitric oxide: a novel strategy for severe localized interstitial pulmonary emphysema in preterm neonatal ventilation.

Abstract:

:We describe the combined use of inhaled nitric oxide and heliox (79% helium and 21% oxygen) as a rescue therapy for a critically ill infant with localized interstitial pulmonary emphysema and pulmonary hypertension. Conventional interventions were ineffective, not feasible, or unlikely to take effect in time, during this infant's acute critical illness. We added heliox based on its known pulmonary effects, and inhaled nitric oxide to improve oxygenation, after echocardiographic evidence of high right-ventricular pressure. The infant made a full recovery. To our knowledge this is the first case report of heliox and inhaled nitric oxide used simultaneously in localized interstitial pulmonary emphysema.

journal_name

Respir Care

journal_title

Respiratory care

authors

Phatak RS,Pairaudeau CF,Smith CJ,Pairaudeau PW,Klonin H

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

1731-8

issue

12

eissn

0020-1324

issn

1943-3654

journal_volume

53

pub_type

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