Analyzing adjuvant radiotherapy suggests a non monotonic radio-sensitivity over tumor volumes.

abstract：BACKGROUND:Genomic selection based on genotyping-by-sequencing (GBS) data could accelerate alfalfa yield gains, if it displayed moderate ability to predict parent breeding values. Its interest would be enhanced by predicting ability also for germplasm/reference populations other than those for which it was defined. Pre...

journal_title：BMC genomics

authors： Annicchiarico P,Nazzicari N,Li X,Wei Y,Pecetti L,Brummer EC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The Transcription Factor (TF) p63 is a master regulator of epidermal development and differentiation as evident from the remarkable skin phenotype of p63 mouse knockouts. Furthermore, ectopic expression of p63 alone is sufficient to convert simple epithelium into stratified epithelial tissues in vivo and p63...

journal_title：BMC genomics

authors： Sethi I,Sinha S,Buck MJ

更新日期：2014-11-29 00:00:00

abstract：BACKGROUND:The mosquito Anopheles gambiae is a major vector of human malaria. Increasing evidence indicates that blood cells (hemocytes) comprise an essential arm of the mosquito innate immune response against both bacteria and malaria parasites. To further characterize the role of hemocytes in mosquito immunity, we un...

journal_title：BMC genomics

authors： Baton LA,Robertson A,Warr E,Strand MR,Dimopoulos G

更新日期：2009-06-05 00:00:00

abstract：BACKGROUND:The sacred lotus (Nelumbo nucifera) is widely cultivated in China for its edible rhizomes and seeds. Traditional plant breeding methods have been used to breed cultivars with increased yields and quality of rhizomes and seeds with limited success. Currently, the available genetic maps and molecular markers i...

journal_title：BMC genomics

authors： Liu Z,Zhu H,Liu Y,Kuang J,Zhou K,Liang F,Liu Z,Wang D,Ke W

更新日期：2016-06-17 00:00:00

abstract：BACKGROUND:Many bacteria can deliver pathogenic proteins (effectors) through type IV secretion systems (T4SSs) to eukaryotic cytoplasm, causing host diseases. The inherent property, such as sequence diversity and global scattering throughout the whole genome, makes it a big challenge to effectively identify the full se...

journal_title：BMC genomics

authors： Wang Y,Wei X,Bao H,Liu SL

更新日期：2014-01-21 00:00:00

abstract：BACKGROUND:Chinese bayberry (Myrica rubra Sieb. & Zucc.) is an important subtropical evergreen fruit tree in southern China. Generally dioecious, the female plants are cultivated for fruit and have been studied extensively, but male plants have received very little attention. Knowledge of males may have a major impact ...

journal_title：BMC genomics

authors： Jia HM,Jiao Y,Wang GY,Li YH,Jia HJ,Wu HX,Chai CY,Dong X,Guo Y,Zhang L,Gao QK,Chen W,Song LJ,van de Weg E,Gao ZS

更新日期：2015-05-19 00:00:00

abstract：BACKGROUND:Extensive genetic diversity in viral populations within infected hosts and the divergence of variants from existing reference genomes impede the analysis of deep viral sequencing data. A de novo population consensus assembly is valuable both as a single linear representation of the population and as a backbo...

journal_title：BMC genomics

authors： Yang X,Charlebois P,Gnerre S,Coole MG,Lennon NJ,Levin JZ,Qu J,Ryan EM,Zody MC,Henn MR

更新日期：2012-09-13 00:00:00

abstract：BACKGROUND:Preterm birth (PTB), birth at <37 weeks of gestation, is a significant global public health problem. World-wide, about 15 million babies are born preterm each year resulting in more than a million deaths of children. Preterm neonates are more prone to problems and need intensive care hospitalization. Health ...

journal_title：BMC genomics

authors： Sheikh IA,Ahmad E,Jamal MS,Rehan M,Assidi M,Tayubi IA,AlBasri SF,Bajouh OS,Turki RF,Abuzenadah AM,Damanhouri GA,Beg MA,Al-Qahtani M

更新日期：2016-10-17 00:00:00

abstract：BACKGROUND:Maternal effects contribute to adaptive significance for shaping various phenotypes of many traits. Potential implications of maternal effects are the cause of expression diversity, but these effects on mRNA expression and alternative splicing (AS) have not been fully elucidated in hybrid animals. RESULTS:T...

journal_title：BMC genomics

authors： Ren L,Yan X,Gao X,Cui J,Yan P,Wu C,Li W,Liu S

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND:Copy number variations (CNVs) are a major form of genetic variations and are involved in animal domestication and genetic adaptation to local environments. We investigated CNVs in the domestic goat (Capra hircus) using Illumina short-read sequencing data, by comparing our lab data for 38 goats from three Chi...

journal_title：BMC genomics

authors： Guo J,Zhong J,Liu GE,Yang L,Li L,Chen G,Song T,Zhang H

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Genomes store information for building and maintaining organisms. Complete sequencing of many genomes provides the opportunity to study and compare global information properties of those genomes. RESULTS:We have analyzed aspects of the information content of Homo sapiens, Mus musculus, Drosophila melanogast...

journal_title：BMC genomics

authors： Liu Z,Venkatesh SS,Maley CC

更新日期：2008-10-30 00:00:00

abstract：BACKGROUND:The steadily increasing number of prokaryotic genomes has accelerated the study of genome evolution; in particular, the availability of sets of genomes from closely related bacteria has facilitated the exploration of the mechanisms underlying genome plasticity. The family Vibrionaceae is found in the Gammapr...

journal_title：BMC genomics

authors： Gu J,Neary J,Cai H,Moshfeghian A,Rodriguez SA,Lilburn TG,Wang Y

更新日期：2009-07-07 00:00:00

abstract：BACKGROUND:Periodic spacing of A-tracts (short runs of A or T) with the DNA helical period of ~10-11 bp is characteristic of intrinsically bent DNA. In eukaryotes, the DNA bending is related to chromatin structure and nucleosome positioning. However, the physiological role of strong sequence periodicity detected in man...

journal_title：BMC genomics

authors： Abel J,Mrázek J

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:Essential genes are indispensable for the survival of living entities. They are the cornerstones of synthetic biology, and are potential candidate targets for antimicrobial and vaccine design. DESCRIPTION:Here we describe the Cluster of Essential Genes (CEG) database, which contains clusters of orthologous ...

journal_title：BMC genomics

authors： Ye YN,Hua ZG,Huang J,Rao N,Guo FB

更新日期：2013-11-09 00:00:00

abstract：BACKGROUND:Fungal plant pathogens belonging to the genus Venturia cause damaging scab diseases of members of the Rosaceae. In terms of economic impact, the most important of these are V. inaequalis, which infects apple, and V. pirina, which is a pathogen of European pear. Given that Venturia fungi colonise the sub-cuti...

journal_title：BMC genomics

authors： Deng CH,Plummer KM,Jones DAB,Mesarich CH,Shiller J,Taranto AP,Robinson AJ,Kastner P,Hall NE,Templeton MD,Bowen JK

更新日期：2017-05-02 00:00:00

abstract：BACKGROUND:Carolacton is a newly identified secondary metabolite causing altered cell morphology and death of Streptococcus mutans biofilm cells. To unravel key regulators mediating these effects, the transcriptional regulatory response network of S. mutans biofilms upon carolacton treatment was constructed and analyze...

journal_title：BMC genomics

authors： Sudhakar P,Reck M,Wang W,He FQ,Wagner-Döbler I,Zeng AP

更新日期：2014-05-12 00:00:00

abstract：BACKGROUND:It is becoming apparent that perhaps as much as half of the genome of the human blood fluke Schistosoma mansoni is constituted of mobile genetic element-related sequences. Non-long terminal repeat (LTR) retrotransposons, related to the LINE elements of mammals, comprise much of this repetitive component of t...

journal_title：BMC genomics

authors： Laha T,Kewgrai N,Loukas A,Brindley PJ

更新日期：2005-11-04 00:00:00

abstract：BACKGROUND:The increasing use of DNA microarrays for genetical genomics studies generates a need for platforms with complete coverage of the genome. We have compared the effective gene coverage in the mouse genome of different commercial and noncommercial oligonucleotide microarray platforms by performing an in-house g...

journal_title：BMC genomics

authors： Verdugo RA,Medrano JF

更新日期：2006-03-21 00:00:00

abstract：BACKGROUND:Transcription factor (TF) GAMYB, belonging to MYB family (named after the gene of the avian myeloblastosis virus) is a master gibberellin (GA)-induced regulatory protein that is crucial for development and germination of cereal grain and involved in anther formation. It activates many genes including high-mo...

journal_title：BMC genomics

authors： Bienias A,Góralska M,Masojć P,Milczarski P,Myśków B

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Genome research in farm animals will expand our basic knowledge of the genetic control of complex traits, and the results will be applied in the livestock industry to improve meat quality and productivity, as well as to reduce the incidence of disease. A combination of quantitative trait locus mapping and mi...

journal_title：BMC genomics

authors： Kim TH,Kim NS,Lim D,Lee KT,Oh JH,Park HS,Jang GW,Kim HY,Jeon M,Choi BH,Lee HY,Chung HY,Kim H

更新日期：2006-02-27 00:00:00

abstract：BACKGROUND:MECP2, the gene mutated in the majority of Rett syndrome cases, is a transcriptional regulator that can activate or repress transcription. Although the transcription regulatory function of MECP2 has been known for over a decade, it remains unclear how transcriptional dysregulation leads to the neurodevelopme...

journal_title：BMC genomics

authors： Lin P,Nicholls L,Assareh H,Fang Z,Amos TG,Edwards RJ,Assareh AA,Voineagu I

更新日期：2016-06-06 00:00:00

abstract：BACKGROUND:Precise identification of three-dimensional genome organization, especially enhancer-promoter interactions (EPIs), is important to deciphering gene regulation, cell differentiation and disease mechanisms. Currently, it is a challenging task to distinguish true interactions from other nearby non-interacting o...

journal_title：BMC genomics

authors： Zeng W,Wu M,Jiang R

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Major secondary metabolites, including flavonoids, caffeine, and theanine, are important components of tea products and are closely related to the taste, flavor, and health benefits of tea. Secondary metabolite biosynthesis in Camellia sinensis is differentially regulated in different tissues during growth a...

journal_title：BMC genomics

authors： Li CF,Zhu Y,Yu Y,Zhao QY,Wang SJ,Wang XC,Yao MZ,Luo D,Li X,Chen L,Yang YJ

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Galileo is one of three members of the P superfamily of DNA transposons. It was originally discovered in Drosophila buzzatii, in which three segregating chromosomal inversions were shown to have been generated by ectopic recombination between Galileo copies. Subsequently, Galileo was identified in six of 12 ...

journal_title：BMC genomics

authors： Gonçalves JW,Valiati VH,Delprat A,Valente VL,Ruiz A

更新日期：2014-09-13 00:00:00

abstract：BACKGROUND:Volvox carteri (V. carteri) is a multicellular green alga used as model system for the evolution of multicellularity. So far, the contribution of small RNA pathways to these phenomena is not understood. Thus, we have sequenced V. carteri Argonaute 3 (VcAGO3)-associated small RNAs from different developmental...

journal_title：BMC genomics

authors： Dueck A,Evers M,Henz SR,Unger K,Eichner N,Merkl R,Berezikov E,Engelmann JC,Weigel D,Wenzl S,Meister G

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:Chloroplasts have their own genomes, independent from nuclear genomes, that play vital roles in growth, which is a major targeted trait for genetic improvement in Populus. Angiosperm chloroplast genomes are maternally inherited, but the chloroplast' variation pattern of poplar at the single-base level during...

journal_title：BMC genomics

authors： Zhu S,Xu M,Wang H,Pan H,Wang G,Huang M

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are a class of noncoding small RNAs (sRNAs) that are 20-24 nucleotides (nt) in length. Extensive studies have indicated that miRNAs play versatile roles in plants, functioning in processes such as growth, development and stress responses. Chilling is a common abiotic stress that seriously ...

journal_title：BMC genomics

authors： Cao X,Wu Z,Jiang F,Zhou R,Yang Z

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Carrot (Daucus carota) is a major food crop in the US and worldwide. Its capacity for storage and its lifecycle as a biennial make it an attractive species for the introduction of foreign genes, especially for oral delivery of vaccines and other therapeutic proteins. Until recently efforts to express recombi...

journal_title：BMC genomics

authors： Ruhlman T,Lee SB,Jansen RK,Hostetler JB,Tallon LJ,Town CD,Daniell H

更新日期：2006-08-31 00:00:00

abstract：BACKGROUND:Vinyl chloride is a widespread groundwater pollutant and Group 1 carcinogen. A previous comparative genomic analysis revealed that the vinyl chloride reductase operon, vcrABC, of Dehalococcoides sp. strain VS is embedded in a horizontally-acquired genomic island that integrated at the single-copy tmRNA gene,...

journal_title：BMC genomics

authors： McMurdie PJ,Hug LA,Edwards EA,Holmes S,Spormann AM

更新日期：2011-06-02 00:00:00

abstract：BACKGROUND:Two strains of the silver fox (Vulpes vulpes), with markedly different behavioral phenotypes, have been developed by long-term selection for behavior. Foxes from the tame strain exhibit friendly behavior towards humans, paralleling the sociability of canine puppies, whereas foxes from the aggressive strain a...

journal_title：BMC genomics

authors： Kukekova AV,Johnson JL,Teiling C,Li L,Oskina IN,Kharlamova AV,Gulevich RG,Padte R,Dubreuil MM,Vladimirova AV,Shepeleva DV,Shikhevich SG,Sun Q,Ponnala L,Temnykh SV,Trut LN,Acland GM

更新日期：2011-10-03 00:00:00