Abstract：
OBJECTIVES:In this study, serum levels of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) between patients with a history of Achilles tendon rupture and blood donor controls were compared, and their relation to mechanical properties of the tendons during healing were studied. METHODS:More than 3 years after injury, serum levels of MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 and MMP-13, TIMP-1 and TIMP-2 in eight patients who had Achilles tendon rupture were measured. Twelve blood donors served as controls. During the early phase of healing, the tendon modulus of elasticity was calculated from radiostereometric data and tendon cross-sectional area. RESULTS:Patients with a history of Achilles tendon rupture had increased levels of MMP-2 (median difference 10%, p=0.01), MMP-7 (median difference 15%, p=0.02) and TIMP-2 (median difference 36%, p=0.02), compared with controls. Levels of MMP-7, measured 3 years after injury, correlated inversely to tendon modulus of elasticity (r(s)=20.83, p=0.02) and positively to tendon elongation (r(s)=0.74, p=0.05) during the early phase of healing. There was a trend towards positive correlation between MMP-7 and cross-sectional area during the early phase of healing (r(s)=0.67, p=0.08). CONCLUSIONS:Patients with a history of Achilles tendon rupture appear to have elevated levels of MMP-2, MMP-7 and TIMP-2 in serum. In these pilot data, the view that the MMP-TIMP system is involved in tendinopathy is supported and that disturbances in proteolytic control might be generalised are suggested.
journal_name
Br J Sports Medjournal_title
British journal of sports medicineauthors
Pasternak B,Schepull T,Eliasson P,Aspenberg Pdoi
10.1136/bjsm.2008.049411subject
Has Abstractpub_date
2010-07-01 00:00:00pages
669-72issue
9eissn
0306-3674issn
1473-0480pii
bjsm.2008.049411journal_volume
44pub_type
杂志文章abstract：BACKGROUND:Some snowboarders listen to music on a personal music player and the objective was to determine if listening to music was associated with injury in a terrain park. METHODS:A case-control study was conducted at a terrain park in Alberta, Canada during the 2008-2009 and 2009-2010 winter seasons. Cases were sn...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsports-2014-093487
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:The 6-minute walk test (6MWT) is a frequently used indicator of functional exercise capacity. The goals of this study were to compare the 6-minute walk performance of three paediatric patient groups with that of healthy peers, to assess differences between published reference values and to investigate which ...
journal_title：British journal of sports medicine
pub_type： 杂志文章,多中心研究
doi：10.1136/bjsm.2008.048512
更新日期：2010-03-01 00:00:00
abstract：AIM:To describe the epidemiology of National Collegiate Athletic Association (NCAA) men's and women's soccer injuries during the 2009/2010-2014/2015 academic years. METHODS:This descriptive epidemiology study used NCAA Injury Surveillance Program (NCAA-ISP) data during the 2009/2010-2014/2015 academic years, from 44 m...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsports-2015-095718
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:The current methods measuring sports activity after anterior cruciate ligament (ACL) injury are commonly restricted to the most knee-demanding sports, and do not consider participation in multiple sports. We therefore developed an online activity survey to prospectively record the monthly participation in al...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsports-2012-092075
更新日期：2014-05-01 00:00:00
abstract：:Cycle helmets that meet UK and US standards have been tested. The mechanisms of energy absorption for frontal and side impacts have been analysed. A good helmet should protect the wearer for impacts up to 15 mph into a rigid flat surface. ...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.24.1.55
更新日期：1990-03-01 00:00:00
abstract：OBJECTIVES:To investigate the influence of anthropometric parameters on race performance in ultra-endurance triathletes. DESIGN:Descriptive field study. SETTING:The Triple Iron Triathlon Germany 2006 in Lensahn over 11.6 km swimming, 540 km cycling and 126.6 km running. SUBJECTS:17 male Caucasian triathletes (mean (...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.2007.039602
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVES:To show how epidemiological data can be presented and analysed in frequency based and risk based formats and how risk based information can simplify management decisions on injury prevention strategies in professional football. METHODS:The club physiotherapists at four English professional football clubs pr...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.36.6.446
更新日期：2002-12-01 00:00:00
abstract：:A case of bilateral anterior glenohumeral dislocation in a young weight trainer is presented. The patient, an insurance clerk, had been using a free weight bar in the bench press position and had become tired when the weight on the bar forced his arms into hyperextension in the mid-abducted position. The humeral shaft...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.32.1.71
更新日期：1998-03-01 00:00:00
abstract：OBJECTIVE:To summarise the literature on the barriers to athletes seeking mental health treatment and cultural influencers of mental health in elite athletes. DESIGN:Systematic review DATA SOURCES: PubMed, Cochrane, Scopus, SportDiscus (Ebsco), and PsycINFO (ProQuest) up to November 2018. ELIGIBILITY CRITERIA FOR SEL...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsports-2019-100710
更新日期：2019-06-01 00:00:00
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journal_title：British journal of sports medicine
pub_type： 杂志文章
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更新日期：2012-04-01 00:00:00
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journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.2005.018366
更新日期：2005-09-01 00:00:00
abstract：BACKGROUND:Accumulating evidence emphasises a relationship between prolonged sitting and increased risk for cardiometabolic disorders and premature death irrespective of the protective effects of physical activity. Primary care physicians have the potential to play a key role in modifying patients' sedentary behaviour ...
journal_title：British journal of sports medicine
pub_type： 杂志文章,多中心研究
doi：10.1136/bjsports-2012-091357
更新日期：2014-10-01 00:00:00
abstract：:In 1975 the authors sent a questionnaire to all players in the Norwegian First Division League Clubs to record the incidence of head injuries due to heading. The conclusion of the questionnaire is that there seems to be a low percentage of serious head injuries. None of the players had been operated on for epi- or sub...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.15.3.163
更新日期：1981-09-01 00:00:00
abstract：BACKGROUND:Little information is available on the effect of strength training on vascular function, particularly in older people. OBJECTIVE:To determine the effect of resistance training on arterial stiffness and endothelial function in older adults. METHOD:Eleven healthy men (mean (SEM) age 64 (1) years) performed 1...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.2006.029538
更新日期：2006-10-01 00:00:00
abstract：:A case of bilateral stress fractures of the ulnae in a Kendo (Japanese fencing) player is reported; the mechanism of the fractures, particularly the difference in the site of fracture between the right and left ulna, is discussed. ...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.32.4.340
更新日期：1998-12-01 00:00:00
abstract：:Swimming pool water slides are becoming increasingly long and adventurous. This case report and survey suggest that they may carry with them a notable risk of friction burns. ...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.29.3.208
更新日期：1995-09-01 00:00:00
abstract：:The recovery pulse and respiration were analysed to determine the level of physical fitness among the physical education and medical students of Banaras Hindu University. The analysis of the data suggested that physical fitness as measured by recovery rate was better in physical education students than in medical stud...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.12.2.93
更新日期：1978-06-01 00:00:00
abstract：:Three tests were conducted to assess the effectiveness of three different intensities of exercise both in reducing blood lactic acid (LA) levels and in influencing subjects' heart rate (HR), following a 2000 m race in a rowing boat. In the first and second tests these variables were investigated during a 13 min recove...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.19.4.199
更新日期：1985-12-01 00:00:00
abstract：OBJECTIVE:To determine the views of retired players about the provision of support services in English professional soccer before and after retirement and to assess the impact of career ending injury on these views. METHOD:An anonymous self administered questionnaire was distributed to 500 former players registered wi...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.36.1.33
更新日期：2002-02-01 00:00:00
abstract：:This study was carried out to determine the rate and types of injuries experienced by boardsailors. Results derive from: (a) a review of hospital medical records for water sports injuries, and (b) a questionnaire-interview of 73 athletes windsurfing on waters in the Galveston area during a hurricane and in moderate an...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.22.3.95
更新日期：1988-09-01 00:00:00
abstract：OBJECTIVES:To assess the results of inferior capsular shift for multidirectional instability of the shoulder in athletes. METHODS:Multidirectional instability was surgically corrected in 53 shoulders in 47 athletes who engaged in contact sports. A history of major trauma was found in eight patients, the others having ...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.36.4.290
更新日期：2002-08-01 00:00:00
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journal_title：British journal of sports medicine
pub_type： 临床试验,杂志文章
doi：10.1136/bjsm.33.5.352
更新日期：1999-10-01 00:00:00
abstract：BACKGROUND:Groin pain in athletes occurs frequently and can be difficult to treat, which may partly be due to the lack of agreement on diagnostic terminology. OBJECTIVE:To perform a short Delphi survey on terminology agreement for groin pain in athletes by a group of experts. METHODS:A selected number of experts were...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsports-2015-094807
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:There are controversial data about the relation between foot morphology and athletic injuries of the lower extremity. Studies in soldiers have shown some relationship, whereas those involving athletes have not shown any significant relationship. The reason for these differences is not clear. OBJECTIVE:To de...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.2003.011478
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:Injuries are common in youth soccer, of which ankle injuries form a significant proportion. However, there is a lack of prospective data on the epidemiology and nature of these injuries. AIM:To prospectively study the incidence of ankle injuries in three Football Association (FA) academies, with particular ...
journal_title：British journal of sports medicine
pub_type： 杂志文章,多中心研究
doi：10.1136/bjsm.2009.067900
更新日期：2011-07-01 00:00:00
abstract：:There is little information on the application of generalized prediction equations to ethnic groups other than Europeans and groups of European descent. The purpose of this study was to crossvalidate conventional equations on a group of 56 Chinese adults. Body density was assessed by underwater weighing and also predi...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.29.1.52
更新日期：1995-03-01 00:00:00
abstract：AIM:The aim of this review is to summarise issues surrounding the measurement of physical activity (PA) by self-report and accelerometry in youth (2-18 years old). Current levels and temporal trends in PA and sport participation and the effect of assessment method on data interpretation will be summarised. METHODS:Rel...
journal_title：British journal of sports medicine
pub_type： 杂志文章,评审
doi：10.1136/bjsports-2011-090190
更新日期：2011-09-01 00:00:00
abstract：:Observations are presented on the electrocardiogram and plasma catecholamine concentrations of 11 healthy men monitored during two rock climbing ascents. A placebo was administered prior to the first climb and an oral dose of the beta blocking agent oxprenolol ("Trasicor") prior to the second. Mean heart rates were 16...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.12.3.125
更新日期：1978-09-01 00:00:00
abstract：OBJECTIVES:To determine in this pilot study whether aerobic exercise affects phenylacetic acid concentration in the urine. METHODS:Twenty healthy men provided 24 hour urine samples on two consecutive days for the determination of phenylacetic acid levels. Before and during day 1, subjects refrained from physical activ...
journal_title：British journal of sports medicine
pub_type： 临床试验,杂志文章
doi：10.1136/bjsm.35.5.342
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:Participation in regular exercise and athletic activities across the lifespan is encouraged to maintain the cardiovascular and musculoskeletal systems and general wellbeing. Before the menopause there is an increased risk of anterior cruciate ligament (ACL) injuries in female athletes, whereas there is an in...
journal_title：British journal of sports medicine
pub_type： 杂志文章
doi：10.1136/bjsm.2008.054296
更新日期：2010-09-01 00:00:00
