Abstract：
:New knowledge of the structure and function of the human genome and novel genomic technologies are being applied to the study of sporadic amyotrophic lateral sclerosis (ALS). These studies can examine tens to hundreds of thousands of items at once, and depend on sophisticated computer processing. Current studies are focused on genetic susceptibility and gene expression and future studies will likely focus on structural variation, gene regulation and non-protein coding regions. The hope is that they will lead to deeper understanding of molecular aspects of the disease and to rational therapeutic targets.
journal_name
Phys Med Rehabil Clin N Amauthors
Ravits J,Traynor BJdoi
10.1016/j.pmr.2008.04.001subject
Has Abstractpub_date
2008-08-01 00:00:00pages
461-77, viiiissue
3eissn
1047-9651issn
1558-1381pii
S1047-9651(08)00028-4journal_volume
19pub_type
杂志文章,评审abstract：:Movement therapy refers to a broad range of Eastern and Western mindful movement-based practices used to treat the mind, body, and spirit concurrently. Forms of movement practice are universal across human culture and exist in ancient history. Research demonstrates forms of movement therapy, such as dance, existed in ...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2020.07.002
更新日期：2020-11-01 00:00:00
abstract：:Orthopedic conditions are common in adults with cerebral palsy (CP). Although CP is argued to be a nonprogressive condition of the brain, the musculoskeletal components tend to worsen and deteriorate over time leading to chronic pain, function limitation, and a decline in mobility. Orthopedic care of adults with CP ha...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2019.09.013
更新日期：2020-02-01 00:00:00
abstract：:Serious neurologic complications following cervical transforaminal epidural steroid injections (CTFESI) and cervical interlaminar epidural steroid injections (CILESI) have been reported. For CILESI, this is caused by aberrant needle placement or space-occupying lesions, such as hematoma or abscess. For CTFESI, this is...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2017.08.012
更新日期：2018-02-01 00:00:00
abstract：:This article focuses on the role of pain and fatigue in aging people who have physical impairments and provides a brief summary of definitions, descriptions, and classifications of pain and fatigue; implications of these secondary conditions on the health and functioning; multidisciplinary assessment and treatment opt...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2009.12.010
更新日期：2010-05-01 00:00:00
abstract：:This review by a 10-member panel of experts in surgical prehabilitation addresses processes that may improve oncologic care. Surgical prehabilitation is the process on the continuum of care that occurs between the time of cancer diagnosis and the beginning of surgical treatment. The panel focused on the current state-...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2016.09.002
更新日期：2017-02-01 00:00:00
abstract：:There are many inherent difficulties in the collection of epidemiologic ski data, but important trends have been identified. Further investigation into controllable risk factors is currently in progress in an attempt to reduce injury incidence, along with prophylactic strength training and conditioning programs. A com...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1999-02-01 00:00:00
abstract：:In this article, the problem of urinary tract infections (UTIs) after spinal cord injury and disorders is defined, the relationship of bladder management to UTIs is discussed, and mechanical and medical strategies for UTI prevention in spinal cord injury and disorders are described. ...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2014.04.002
更新日期：2014-08-01 00:00:00
abstract：:CRF is indisputably a significant problem with important public health and medical economic implications. As the prevalence of cancer survivorship grows, the impact of CRF will increase. Physiatrists have not historically played an active role in caring for affected patients. In the author's opinion, this is unfortuna...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2008.12.005
更新日期：2009-05-01 00:00:00
abstract：:Conservative management of low back pain includes the use of lumbar epidural steroid injections, which have become increasingly more popular in the last 20 years. The body of literature regarding the efficacy of these injections is vast, conflicting, and difficult to summarize. This article reviews the updated evidenc...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2010.10.006
更新日期：2011-02-01 00:00:00
abstract：:There has been an increase in the use of ultrasound (US) to help guide interventional procedures involving the musculoskeletal system. To perform these procedures safely and accurately, two steps must occur. First, the appropriate structure must be localized using diagnostic US imaging. Second, a needle must be guided...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2010.04.004
更新日期：2010-08-01 00:00:00
abstract：:Traumatic spinal cord injury (SCI) often results in several life-altering impairments, including paralysis, sensory loss, and neurogenic bowel/bladder dysfunction. Some of these SCI-related conditions can be accommodated with compensatory strategies. Perhaps no SCI-associated condition is more troublesome and recalcit...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2020.03.004
更新日期：2020-08-01 00:00:00
abstract：:Electrodiagnosis can classify hereditary motor and sensory neuropathies (HMSN) into two basic types: primarily demyelinating with secondary axonal loss and primarily axonal. For the most part, the various forms of HMSN show uniform symmetric nerve conduction slowing, in contrast to acquired neuropathies, which may be ...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s1047-9651(02)00127-4
更新日期：2003-05-01 00:00:00
abstract：:Telerehabilitation refers to the virtual delivery of rehabilitation services into the patient's home. This methodology has shown to be advantageous when used to enhance or replace conventional therapy to overcome geographic, physical, and cognitive barriers. The exponential growth of technology has led to the developm...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2018.12.002
更新日期：2019-05-01 00:00:00
abstract：:The rehabilitation medicine prescription is a communication tool between the referring physician and the rehabilitation team in both the inpatient and outpatient settings. This instrument is critical in both directing a course of treatment as well as minimizing risk to the patient during the treatment sessions. The go...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2012.02.002
更新日期：2012-05-01 00:00:00
abstract：:Focal entrapment neuropathies in the foot, as compared to those of the hand, represent a daunting diagnostic challenge to many electromyographers. This article emphasizes an understanding of the anatomy of the foot as a fundamental key to its electrodiagnostic evaluation. The anatomic course of specific nerves will be...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1998-11-01 00:00:00
abstract：:As more people survive burn injuries, there is an increasing focus on managing the complications of burn injuries with the ultimate goal of improving survivors' quality of life. Musculoskeletal and neurologic sequelae are significant complications of burn injury. Electrical injury is a subcategory of burns with multip...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2011.01.003
更新日期：2011-05-01 00:00:00
abstract：:Understanding poststroke upper limb impairment is essential to planning therapeutic efforts to restore function. However, determining which upper limb impairment to treat and how is complex because the impairments are not static and multiple impairments may be present simultaneously. How impairments contribute to uppe...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2015.06.008
更新日期：2015-11-01 00:00:00
abstract：:Tone management is one of the primary roles of a pediatric physiatrist. Hypertonicity frequently inhibits normal movement patterns in children with central nervous system lesions but at times can reinforce muscle group firing and be useful for a child's function. Treatment approaches should be individualized based on ...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2014.09.008
更新日期：2015-02-01 00:00:00
abstract：:The following guideline covers a wide array of shoulder conditions seen in the workers' compensation, as well as the nonworkers' compensation, population. The guideline is intended to help establish work relatedness and aid in making the diagnosis of shoulder injuries and degenerative conditions. It also provides a no...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2015.04.007
更新日期：2015-08-01 00:00:00
abstract：:Frailty is a complex subject, and all aspects of frailty are intertwined. This article identifies and discusses the individual aspects of frailty. These aspects, including sarcopenia, nutrition, obesity, relative strength, inflammatory markers, osteopenia and osteoporosis, aerobic capacity, absolute strength, balance,...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2007.04.004
更新日期：2007-08-01 00:00:00
abstract：:Clinical and electrical myotonia is caused by a small group of neuromuscular disorders. This article reviews myotonia and its differential diagnosis. The use of electrodiagnostic testing to evaluate the primary myotonic disorders (myotonic dystrophy and the nondystrophic myotonias) is also discussed. ...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2012.08.015
更新日期：2013-02-01 00:00:00
abstract：:Volleyball has become one of the world's most popular participatory sports in recent years. There are many dynamic skills and movements needed to play the game. As a result, many overuse and traumatic injuries to the extremities and back may occur. This article addresses the history of the sport and its terminology. C...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1999-02-01 00:00:00
abstract：:Fencing is a sport in which two people attempt to score points by making their weapon (epee, foil, or saber) contact their opponent. The most common types of injury seen in fencing are weapon injuries; strains, sprains, and trauma; and nontraumatic injuries, the pathologic findings of which are discussed in this artic...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2006.05.008
更新日期：2006-08-01 00:00:00
abstract：:Imaging sports injuries is challenging, interesting, and evolving. The use of imaging and its various modalities depends on the clinicians' and radiologists' comfort and facility with those modalities, with the clinician playing the pivotal role. Imaging can be used to make diagnoses, define prognoses, influence treat...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
abstract：:Neuromuscular ultrasonography can be used both descriptively and quantitatively in the evaluation of patients with neuromuscular disorders. This article reviews the quantitative use of this technology, particularly measurements of the size and echogenicity of nerve and muscle, as a tool for assessing the severity, pro...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2011.11.009
更新日期：2012-02-01 00:00:00
abstract：:The role of the physiatrist in provision of medicolegal expert testimony in cases involving traumatic brain injury is challenging and complex. This article provides an overview of how such work should be conducted from a practical perspective including discussion of ethical, legal, medical, and business aspects of suc...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2016.12.012
更新日期：2017-05-01 00:00:00
abstract：:Chronic pelvic pain can result from various intra- and extra-pelvic etiologies. Although patient history and physical examination may narrow the differential diagnosis, frequently, the different etiologies have overlapping presentations. Imaging examinations such as US and/or MR imaging may help delineate the cause of...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2017.03.004
更新日期：2017-08-01 00:00:00
abstract：:BT is likely effective in controlling spasticity in the smaller muscles of the arm and hand, although there has been only one large controlled trial. For lower limb spasticity, the outcomes are more mixed. No large randomized, controlled trials have been done, and the larger size of the muscles results in a decreased ...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s1047-9651(03)00064-0
更新日期：2003-11-01 00:00:00
abstract：:Neuromuscular disorders associated with monoclonal gammopathies are usually uncovered in approximately 10% of patients presenting with peripheral neuropathy complaints. This discovery should prompt further evaluation for underlying plasma cell dyscrasias. The most frequent monoclonal disorders associated with neuropat...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pmr.2007.10.005
更新日期：2008-02-01 00:00:00
abstract：:These cases represent individuals who feel they have a severe impairment and are "disabled." They have been labeled with fibromyalgia. They are truly distressed. Their symptoms, their courses, are more chronic and refractory than those of medically ill patients, and they are high users of medical services, laboratory ...
journal_title：Physical medicine and rehabilitation clinics of North America
pub_type： 杂志文章
doi：
更新日期：2001-08-01 00:00:00
