Fournier's gangrene and scrotal ulcerations during all-trans-retinoic acid therapy for acute promyelocytic leukemia.

abstract：BACKGROUND:Sorafenib targets multiple pathways thought to be crucial in growth of plexiform neurofibroma (PN) in children with neurofibromatosis type 1 (NF1). Sorafenib has been tolerated with manageable toxicities in adults and children with refractory cancer. We conducted a separate study in this population. Monitori...

journal_title：Pediatric blood & cancer

authors： Kim A,Dombi E,Tepas K,Fox E,Martin S,Wolters P,Balis FM,Jayaprakash N,Turkbey B,Muradyan N,Choyke PL,Reddy A,Korf B,Widemann BC

更新日期：2013-03-01 00:00:00

abstract：:Anaplastic oligodendroglioma (AO) is rare in children. Treatment typically consists of varying combinations of surgery, chemotherapy, and radiotherapy. We present a pediatric case of frontal lobe AO with periventricular subcallosal extension and local leptomeningeal involvement. The isocitrate dehydrogenase (IDH) wild...

journal_title：Pediatric blood & cancer

authors： Sorge C,Li R,Singh S,Reddy AT,Solomon DA,Perry A,Friedman GK

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Follicular variant of papillary thyroid carcinoma (FVPTC) has been shown to be an intermediate entity between papillary (PTC) and follicular/Hurtle cell (FTC) thyroid carcinoma in adults. However, the tumor characteristics and prognosis of FVPTCs has not been studied in the pediatric population and is the fo...

journal_title：Pediatric blood & cancer

authors： Lerner J,Goldfarb M

更新日期：2015-11-01 00:00:00

abstract：:Congenital hypotransferrinemia (OMIM 209300) is an extremely rare disorder of inherited iron metabolism. Since its description in 1961, only 16 cases have been reported. The defective gene and molecular defect causing this disorder and clinicolaboratory findings seen in the homozygous and heterozygous states have been...

journal_title：Pediatric blood & cancer

authors： Aslan D

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:We sought to better define the role of hematopoietic cell transplantation (HCT) in first remission (CR1) for high-risk pediatric acute myeloid leukemia (AML). PROCEDURES:Outcomes were compared among patients aged less than 21 years with cytogenetically defined poor-risk AML treated with chemotherapy, matche...

journal_title：Pediatric blood & cancer

authors： Kelly MJ,Horan JT,Alonzo TA,Eapen M,Gerbing RB,He W,Lange BJ,Parsons SK,Woods WG

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Sleep disordered breathing (SDB) is emerging as a significant health condition for children. The purpose of this study is to evaluate SDB symptoms in childhood cancer survivors and identify associations with quality of life (QOL) and psychological symptoms. PROCEDURE:A sample of 62 survivors aged 8-18 years...

journal_title：Pediatric blood & cancer

authors： Kathy R,Anna G,Gallicchio L,Gamaldo C

更新日期：2015-04-01 00:00:00

abstract：:We report two survivors of Wilms tumor (WT) who developed inflammatory myofibroblastic tumor (IMT). The first patient had IMT in the mainstem bronchus 1 year after WT therapy that included vincristine, dactinomycin, doxorubicin (VDA) and whole lung radiation therapy (XRT). The second patient had IMT in the cecum 7 yea...

journal_title：Pediatric blood & cancer

authors： Ortiz MV,Rossi CT,Hill DA,Guzzetta PC,Qureshi F,Dome JS

更新日期：2015-06-01 00:00:00

abstract：:Langerhans cell histiocytosis is known to mimic many other conditions. We present two patients where anti-tubercular therapy was instituted when clinical and radiological features suggested tuberculosis. The correct diagnosis of histiocytosis was reached only on further work-up including immunohistochemistry following...

journal_title：Pediatric blood & cancer

authors： Sharma P,Dhingra KK,Sural S,Mandal AK,Singh T

更新日期：2009-07-01 00:00:00

abstract：:Phytosterolemia is a rare autosomal recessive sterol storage disease caused by mutations in ABCG5 and ABCG8 genes. A 9-year-old Turkish boy who was presented with exclusively hematologic abnormalities had elevated plant sterol levels. Sequencing of ABCG5 and ABCG8 genes revealed a novel homozygous IVS10-1 G>T mutation...

journal_title：Pediatric blood & cancer

authors： Kaya Z,Niu DM,Yorulmaz A,Tekin A,Gürsel T

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Previous studies of children with homozygous sickle cell anemia (SCA) show impaired growth and maturation. The correlation of this suboptimal growth with metabolic and hematological factors during puberty is poorly understood. PROCEDURE:We studied a group of pre-adolescent children with SCA (19 males, 14 fe...

journal_title：Pediatric blood & cancer

authors： Rhodes M,Akohoue SA,Shankar SM,Fleming I,Qi An A,Yu C,Acra S,Buchowski MS

更新日期：2009-10-01 00:00:00

abstract：:A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely...

journal_title：Pediatric blood & cancer

authors： Maeda M,Tsuda A,Yamanishi S,Uchikoba Y,Fukunaga Y,Okita H,Hata J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Neuroblastoma (NB) is cytogenetically characterized by a number of non-random events. However, knowledge is limited concerning the timing of occurrence and inter-action of many of these events. METHODS:Karyotypic patterns were obtained from a study group of 49 NB tumors that had been analyzed by conventiona...

journal_title：Pediatric blood & cancer

authors： Betts DR,Cohen N,Leibundgut KE,Kühne T,Caflisch U,Greiner J,Traktenbrot L,Niggli FK

更新日期：2005-02-01 00:00:00

abstract：:A 12-year-old boy in third remission of an acute lymphoblastic leukaemia developed infection of lung and paranasal sinuses with Aspergillus flavus in neutropenia. Because of the high risk of leukaemia-relapse bone marrow transplantation (BMT) from a matched unrelated donor was carried out despite invasive pulmonary as...

journal_title：Pediatric blood & cancer

authors： Schuster F,Moelter C,Schmid I,Graubner UB,Kammer B,Belohradsky BH,Führer M

更新日期：2005-06-15 00:00:00

abstract：BACKGROUND:Malnutrition is a pro-inflammatory state, yet data on nutritional risk factors and development of acute graft-versus-host disease (aGVHD) are extremely limited. PROCEDURE:We conducted a retrospective cohort analysis of pediatric patients up to age 21 years who underwent allogeneic hematopoietic stem cell tr...

journal_title：Pediatric blood & cancer

authors： Kerby EH,Li Y,Getz KD,Smith EC,Smith LT,Bunin NJ,Seif AE

更新日期：2018-02-01 00:00:00

abstract：:Malignant degeneration frequently arises from preexisting plexiform neurofibroma in patients with neurofibromatosis type 1 (NF1). Image guided biopsy for diagnostic purposes, such as with CT guidance, can be technically challenging in these patients, as CT cannot distinguish malignant from benign areas within the same...

journal_title：Pediatric blood & cancer

authors： Koethe Y,Widemann BC,Hajjar F,Wood BJ,Venkatesan AM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Systematic assessment of emotional distress is recommended in after care. Yet, it is unclear if parent report may be used as a proxy of child report. The aim of this study was to assess agreements and differences and explore possible moderators of disagreement between child and parent ratings. METHODS:Sixty...

journal_title：Pediatric blood & cancer

authors： Abate C,Lippé S,Bertout L,Drouin S,Krajinovic M,Rondeau É,Sinnett D,Laverdière C,Sultan S

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:Palliative radiation therapy (pRT) is often used to improve quality of life for pediatric patients. Though palliative doses are generally lower than those for cure, pRT may still introduce undesirable effects. The decision to pursue additional therapy for a child may be challenging and depends on parents' kn...

journal_title：Pediatric blood & cancer

authors： Lee BK,Boyle PJ,Zaslowe-Dude C,Wolfe J,Marcus KJ

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Premature newborns are vulnerable to iron imbalance, although the iron homeostasis during the perinatal period remains unclear. To clarify the iron metabolism of premature infants, we measured serum prohepcidin concentrations of preterm infants, and analyzed the association with iron parameters. METHODS:Sev...

journal_title：Pediatric blood & cancer

authors： Kitajima J,Ohga S,Kinjo T,Ochiai M,Takahata Y,Honjo S,Hara T

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:To report the final analysis of survival outcomes for children with newly diagnosed high-grade glioma (HGG) treated on the "Head Start" (HS) II and III protocols with chemotherapy and intent to avoid irradiation in children <6 years old. PATIENTS AND METHODS:Between 1997 and 2009, 32 eligible children were enr...

journal_title：Pediatric blood & cancer

authors： Espinoza JC,Haley K,Patel N,Dhall G,Gardner S,Allen J,Torkildson J,Cornelius A,Rassekh R,Bedros A,Etzl M,Garvin J,Pradhan K,Corbett R,Sullivan M,McGowage G,Stein D,Jasty R,Sands SA,Ji L,Sposto R,Finlay JL

更新日期：2016-10-01 00:00:00

abstract：:Survivorship care is a major area of focus in the holistic management of childhood cancer with current knowledge and information almost exclusively from high-income countries. In this review, we summarize the state of scientific knowledge, service delivery, advocacy initiatives, and research efforts in this field in I...

journal_title：Pediatric blood & cancer

authors： Arora RS,Arora PR,Seth R,Sharma S,Kumar C,Dhamankar V,Kurkure P,Prasad M

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The Kids ITP Tools (KIT) is a disease-specific measure of health-related quality of life for children with immune thrombocytopenia (ITP). To facilitate use in international trials it has been cross-culturally adapted for France, Germany, the United Kingdom and Uruguay. This study assessed the validity and re...

journal_title：Pediatric blood & cancer

authors： Klaassen RJ,Blanchette V,Burke TA,Wakefield C,Grainger JD,Gaedicke G,Riedlinger A,Dufort G,Citrin E,Reguerre Y,Pellier I,Curtis C,Young NL

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Using patient-reported outcomes (PROs) in clinical practice has been shown to enhance detection of health-related quality of life problems and satisfaction with care in children with cancer. This study seeks to identify which PRO information healthcare professionals (HCPs) find useful and what the perceived ...

journal_title：Pediatric blood & cancer

authors： Schepers SA,Haverman L,Zadeh S,Grootenhuis MA,Wiener L

更新日期：2016-12-01 00:00:00

abstract：:This review of the experience of high dose chemotherapy in patients with recurrent or refractory intracranial germ cell tumor confirms that sustained tumor control can be achieved with this modality both in germinoma and non-germinomatous germ cell tumors. Data from cooperative groups in Europe and North America sugge...

journal_title：Pediatric blood & cancer

authors： Bouffet E

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Pheochromocytomas (PCs) are neuroendocrine tumors arising from the chromaffin cells of the adrenal gland, and paragangliomas (PGLs) are their extra-adrenal counterparts arising from ganglia along the sympathetic/parasympathetic chain. Surgery is the cornerstone of treatment. A sporatic or inherited germline ...

journal_title：Pediatric blood & cancer

authors： Virgone C,Andreetta M,Avanzini S,Chiaravalli S,De Pasquale D,Crocoli A,Inserra A,D'Angelo P,Alaggio R,Opocher G,Cecchetto G,Ferrari A,Bisogno G,Dall'Igna P

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Ewing sarcoma (EWS) is rarely diagnosed as a second malignancy. We sought to describe a cohort of patients with secondary EWS and investigate if patient characteristics and survival differ between patients with secondary and primary EWS. PROCEDURE:Patients with EWS or peripheral primitive neuroectodermal tu...

journal_title：Pediatric blood & cancer

authors： Applebaum MA,Goldsby R,Neuhaus J,DuBois SG

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Acute and chronic clinical manifestations of sickle-cell disease (SCD) lead to significant healthcare utilization, especially of the emergency department (ED). Limited population-level data are available in SCD with the ability to connect patients to visits, leaving us with minimal description of utilization...

journal_title：Pediatric blood & cancer

authors： Wolfson JA,Schrager SM,Coates TD,Kipke MD

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Resource-rich countries tend to have a higher incidence of childhood acute lymphoblastic leukemia (ALL), whereas lower rates are seen in more deprived countries. This study describes the incidence of childhood acute leukemia in Brazil, an upper middle-income country, based on data from 16 population-based ca...

journal_title：Pediatric blood & cancer

authors： de Souza Reis R Sr,de Camargo B,de Oliveira Santos M,de Oliveira JM,Azevedo Silva F,Pombo-de-Oliveira MS

更新日期：2011-01-01 00:00:00

abstract：:Children with sickle cell anemia (SCA) have low bone mass though bone turnover has not been well described. In this study, growth and pubertal development were assessed twice, 1 year apart, in 80 young subjects with type-SS SCA, while whole body bone mineral content (BMC) and density where measured in a subset (n = 46...

journal_title：Pediatric blood & cancer

authors： Fung EB,Kawchak DA,Zemel BS,Rovner AJ,Ohene-Frempong K,Stallings VA

更新日期：2008-03-01 00:00:00

abstract：:The rejection rate in cord blood transplants for chronic Epstein-Bar virus-associated T or natural killer cell lymphoproliferative diseases using our standard reduced-intensity conditioning "LPAM140 regimen," which includes fludarabine, melphalan (LPAM), etoposide, and antithymocyte globulin, has been high. To ensure ...

journal_title：Pediatric blood & cancer

authors： Mayumi A,Sawada A,Sato M,Shimizu M,Ioi A,Higuchi K,Yasui M,Kawa K,Inoue M

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Ewing tumors are the most frequent malignant tumors of the chest wall in children and young adults. Surgical management of these tumors can be challenging. Optimal local control remains controversial. The aim of this study was to analyze treatment, outcome, and surgical procedures in patients with thoracic t...

journal_title：Pediatric blood & cancer

authors： Seitz G,Urla C,Sparber-Sauer M,Schuck A,Vokuhl C,Blank B,Klingebiel T,Kazanowska B,Fuchs J,Koscielniak E

更新日期：2019-08-01 00:00:00