Abstract:
BACKGROUND:There is a close anatomical relationship between the right coronary cusp (RCC) and noncoronary aortic cusp (NCC) and sites recording His bundle (HB) activation in the right ventricle (RV). OBJECTIVE:The purpose of this study was to examine the electrocardiographic and electrophysiological characteristics of ventricular arrhythmias (VAs) that originate near the HB and their potential as predictors of successful catheter ablation sites. METHODS:We studied 147 consecutive patients undergoing successful catheter ablation of idiopathic VAs originating from the ventricular outflow tract of either ventricle or the HB region. RESULTS:In 13 (9%) patients with an origin in the RCC (n = 5), NCC (n = 1), or RV HB region (n = 7), the local RV activation in the HB region preceded the QRS onset. In two VAs originating from the RCC or NCC, failed radiofrequency applications near the HB region in the RV delayed the near-field ventricular electrogram and separated the far-field electrograms before the QRS onset in the HB region. The QRS transition in the precordial leads did not discriminate between an RV origin near the HB and an NCC or RCC origin. A QS pattern in lead aVL might be helpful for predicting an RCC origin. CONCLUSIONS:VAs originating near the HB have similar electrocardiographic and electrophysiological characteristics, regardless of whether the ablation site is in the RV or aortic sinuses because of the close anatomical relationship of these structures and rapid transseptal conduction. When RV mapping reveals an earliest ventricular activation in the HB region during VAs, mapping in the RCC and NCC should be added to accurately identify the site of origin.
journal_name
Heart Rhythmjournal_title
Heart rhythmauthors
Yamada T,McElderry HT,Doppalapudi H,Kay GNdoi
10.1016/j.hrthm.2007.08.032subject
Has Abstractpub_date
2008-01-01 00:00:00pages
37-42issue
1eissn
1547-5271issn
1556-3871pii
S1547-5271(07)00899-5journal_volume
5pub_type
杂志文章相关文献
HEART RHYTHM文献大全abstract:BACKGROUND:Class 1 antiarrhythmic drugs are highly effective in restoring and maintaining sinus rhythm in atrial fibrillation patients but carry a risk of ventricular tachyarrhythmia. The antianginal agent ranolazine is a prototypic atrial-selective voltage-gated Na+ channel blocker but the mechanisms underlying its at...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2017.06.012
更新日期:2017-11-01 00:00:00
abstract::Ventricular fibrillation (VF), despite its declining incidence as a cause of sudden cardiac death, is still a major health problem. The underlying mechanisms for the maintenance of VF are still disputed. Studies suggest that VF is unlikely one static mechanism but rather a dynamic process of electrical derangement tha...
journal_title:Heart rhythm
pub_type: 杂志文章,评审
doi:10.1016/j.hrthm.2008.11.005
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Pulmonary vein isolation (PVI) is a central procedure for the treatment of paroxysmal atrial fibrillation (PAF). However, in patients with PAF and structural atrial disease, PVI may fail and cause progressive atrial remodeling, often leading to persistent/permanent atrial fibrillation. OBJECTIVE:We performe...
journal_title:Heart rhythm
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.hrthm.2015.06.009
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Patients with chronic right ventricular pacing (RVP) upgraded to cardiac resynchronization therapy (CRT) have been excluded from the majority of clinical trials of CRT. Little is known about the predictors of response in this population. We hypothesized that reversal of RVP-induced electrical dyssynchrony (i...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2012.09.018
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Syncope in Brugada syndrome (BrS) patients is a sign of increased risk for sudden cardiac death and usually is ascribed to cardiac arrhythmias. However, syncope often occurs in the general population, mostly from nonarrhythmic causes (eg, reflex syncope). OBJECTIVE:The purpose of this study was to distingui...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2014.10.014
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Left atrial appendage (LAA) occlusion with WATCHMAN has emerged as viable alternative to vitamin K antagonists in randomized controlled trials. OBJECTIVE:EWOLUTION was designed to provide data in routine practice from a prospective multicenter registry. METHODS:A total of 1025 patients scheduled for a WATC...
journal_title:Heart rhythm
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.hrthm.2017.05.038
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Pulmonary vein isolation by cryoballoon ablation is an accepted method of treating atrial fibrillation. Little data exist regarding factors affecting late electrical reconnection of pulmonary veins following cryoballoon ablation. OBJECTIVE:To investigate factors determining pulmonary vein reconnection in pa...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2013.06.014
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:We examined nonprescription weight-loss supplements marketed on the Internet for ingredients with potential arrhythmogenic and life-threatening cardiac adverse effects. OBJECTIVE:We aimed to define the risks of life-threatening cardiac adverse effects that are associated with weight-loss supplements markete...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2009.02.021
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Optogenetics uses light to regulate cardiac rhythms and terminate malignant arrhythmias. OBJECTIVE:The purpose of this study was to investigate the long-term validity of optical capture properties based on virus-transfected channelrhodopsin-2 (ChR2) and evaluate the effects of optogenetic-based defibrillati...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2020.08.002
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Atrial tachyarrhythmias (AT) are considered progressive diseases. Several rhythm control therapies for treatment of AT have been proposed. OBJECTIVES:The Italian AT500 Registry was designed to prospectively study long-term AT evolution in patients paced for the brady-tachy form of sinus node disease (BT-SND...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2005.07.011
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Narrow QRS tachycardia or premature beat with bystander atrial activation or ventricular-atrial dissociation is an unusual arrhythmia that can present diagnostic and therapeutic challenges. When ventricular-atrial conduction is robust, these arrhythmias can be difficult to distinguish from atrioventricular n...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2018.08.006
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:QRS transition zone is related to the electrical axis of the heart in the horizontal plane and is easily determined from the precordial leads of a standard 12-lead ECG. However, whether delayed QRS transition, or clockwise rotation of the heart, carries prognostic implications and predicts sudden cardiac dea...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2014.08.014
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Bidirectional ventricular tachycardia (BVT), which is characterized by an alternating beat-to-beat ECG QRS axis, is a rare but intriguing arrhythmia associated with digitalis toxicity, familial catecholaminergic polymorphic ventricular tachycardia (CPVT), and several other conditions that predispose cardiac ...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2010.11.038
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:We previously showed that the cardioversion threshold (CVT) for ventricular tachycardia (VT) is phase dependent when a single monophasic shock (1MP) is used. OBJECTIVE:The purpose of this study was to extend these findings to a biphasic shock (1BP) and to compare the efficacy of phase-independent multiple m...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2009.03.015
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF) ablation is increasingly used in patients with reduced left ventricular ejection fraction (LVEF), but long-term outcomes are still unknown. OBJECTIVE:To assess the long-term effects of AF ablation in patients with systolic heart failure according to rhythm outcome. METHODS:We inclu...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2013.12.031
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Causative arrhythmias of sudden cardiac arrest (SCA) are changing in this age of improved coronary care. OBJECTIVE:The purpose of this study was to examine the frequency of terminal arrhythmias and the electrical events prior to SCA. METHODS:We analyzed 24-hour Holter recordings of 132 patients enrolled fr...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2014.04.036
更新日期:2014-08-01 00:00:00
abstract::The underlying mechanisms and temporal course of complete heart block (CHB) after blunt cardiac injuries (BCIs) are poorly understood, and a systematic analysis of available data is lacking. In this systematic review, PubMed was searched for publications of reported cases of CHB-BCI analyzing clinical findings, electr...
journal_title:Heart rhythm
pub_type: 杂志文章,评审
doi:10.1016/j.hrthm.2017.05.040
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Ventricular tachycardia (VT) in patients with idiopathic dilated cardiomyopathy often originates from the basal left ventricular myocardium and also can originate from the conduction system. The basal left ventricular myocardium reaches to the base of the aortic sinus cusps. OBJECTIVE:The purpose of this st...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2010.10.045
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Left atrial appendage (LAA) ligation with the Lariat device is a therapeutic option to prevent thromboembolic stoke in patients with nonvalvular atrial fibrillation (AF) at high risk for systemic thromboembolization and bleeding related to use of anticoagulation. In rare cases, this procedure could leave the...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2014.06.035
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Regular alcohol intake is an important modifiable risk factor associated with atrial fibrillation (AF) and left atrial (LA) dilation. OBJECTIVE:The purpose of this study was to determine the impact of different degrees of alcohol consumption on atrial remodeling using high-density electroanatomic mapping. ...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2018.10.041
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Sudden cardiac death is frequent in patients with lamin A/C gene (LMNA) mutations and may be related to ventricular arrhythmias (VA). OBJECTIVE:To evaluate a strategy of prophylactic implantable cardioverter-defibrillator (ICD) implantation in LMNA mutation carriers with significant cardiac conduction disor...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2013.06.020
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:QRS morphology and QRS duration (QRSd) determine cardiac resynchronization therapy (CRT) candidate selection but criteria require refinement. OBJECTIVE:To assess CRT effect according to QRSd, treated by dichotomization vs a continuous function, and modulation by gender. METHODS:Patients selected were those...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2014.04.001
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) in the mouse is expressed in the developing cardiac conduction system (CCS). In the sinoatrial node (SAN), HCN4 is the predominant isoform responsible for the funny current. To date, no data are available on HCN4 expression during chicken C...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2011.03.043
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The mechanism of bundle branch reentrant tachycardia has been described, and ablation of the right bundle branch (RBB) is a curative approach. OBJECTIVE:The purpose of this study was to evaluate the left bundle branch (LBB)-Purkinje system during sinus rhythm and to test the feasibility of ablating the LBB ...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2008.09.028
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF) is more prevalent in Caucasians than in persons of other racial/ethnic groups. OBJECTIVE:The purpose of this study was to examine the association between race/ethnicity and new-onset postoperative atrial fibrillation (POAF) after coronary artery bypass grafting (CABG). METHODS:Data...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2010.06.037
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:To facilitate catheter ablation of ventricular tachycardia (VT), we previously developed an automated method to identify sources of left ventricular (LV) activation in real time using 12-lead electrocardiography (ECG), the accuracy of which depends on acquisition of a complete electroanatomic (EA) map. OBJE...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.10.025
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:There is limited information on gender differences in patients with Brugada syndrome (BrS) who experienced arrhythmic events (AEs). OBJECTIVE:The purpose of this study was to compare clinical, electrocardiographic (ECG), electrophysiological, and genetic characteristics between males and females in patients...
journal_title:Heart rhythm
pub_type: 杂志文章,多中心研究
doi:10.1016/j.hrthm.2018.06.019
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Pulmonary vein isolation (PVI) is commonly performed in patients with drug-refractory symptomatic paroxysmal atrial fibrillation (PAF). However, the very long-term follow-up result is limited. OBJECTIVE:We aimed to investigate 10-year ablation outcomes in patients with PAF and long-term follow-up results af...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.03.028
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Right ventricular myocardial pacing leads to nonphysiological activation of heart ventricles. Contrary to this, His bundle pacing preserves their fast activation. Ultra-high-frequency electrocardiography (UHF-ECG) is a novel tool for ventricular depolarization assessment. OBJECTIVE:The purpose of this study...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.11.016
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:There is limited information on ethnic differences between patients with Brugada syndrome (BrS) and arrhythmic events (AEs). OBJECTIVE:The purpose of this study was to compare clinical, electrocardiographic (ECG), electrophysiological, and genetic characteristics between white and Asian patients with BrS an...
journal_title:Heart rhythm
pub_type: 杂志文章,多中心研究
doi:10.1016/j.hrthm.2019.07.003
更新日期:2019-10-01 00:00:00