Abstract:
:Taking into account the important role of oestrogen and NK cells in the process of cancerogenesis, the content of receptors for steroid hormones and NK cell activity was investigated in 31 patients with breast cancer. The analysis of steroid receptors showed the usual distribution with regard to clinical stage. The values of NK cell ativity in peripheral blood of these patients were decreased x = 38.27 +/- 2.84%) compared to controls (X = 57.76 +/- 2.21%), especially in advanced stages, as was previously shown fot this malignancy. General analysis of values for these two parameters did not show a correlation of NK activity and content of steroid receptors. However, the presence of positive progesterone receptors, which reflects the active effect of oestrogen, was associated with very low NK activity (n = 12 PR+, NK x = 29.47 +/- 3.18%), indicating possible negative regulation of immunological parameters by estrogen.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Konjević G,Branković-Magić M,Nikolić-Vukosavljević D,Spuzić Isubject
Has Abstractpub_date
1994-05-01 00:00:00pages
139-42issue
5-6eissn
0370-8179issn
2406-0895journal_volume
122pub_type
杂志文章abstract:INTRODUCTION:Vascular remodelling is an adaptive process involving the adjustment of the structure and function of blood vessels to long-term changes in haemodynamic conditions. This process leads to structural alterations within vessel walls in different cardiovascular diseases, such as hypertension, atherosclerosis, ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh06s1009l
更新日期:2006-05-01 00:00:00
abstract:INTRODUCTION:The prevalence of obesity is rising to epidemic proportions at the alarming rate in both developed and underdeveloped countries around the world. Current prevalence data from individual national studies suggest that the obesity prevalence in the European countries ranges from 10% to 20% for men, and 10% to...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0702061g
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Cardiovascular autonomic modulation is altered in patients with essential hypertension. OBJECTIVE:To evaluate acute and long-term effects of amlodipine on cardiovascular autonomic function and haemodynamic status in patients with mild essential hypertension. METHODS:Ninety patients (43 male, mean age 52....
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0908371m
更新日期:2009-07-01 00:00:00
abstract:INTRODUCTION:Neurofibromatosis type 1 is one of the most common genetically transmitted diseases with a high index of spontaneous mutations and extremely varied and unpredictable clinical manifestations. It is diagnosed by the existence of certain clinical criteria. The presence of numerous localised cutaneous neurofib...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0806295t
更新日期:2008-05-01 00:00:00
abstract:INTRODUCTION:Because apical periodontitis is recognizably an infectious disease, elimination or reduction of intracanal bacteria is of utmost importance for optimum treatment outcome. OBJECTIVE:The prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals was studied Also, the effect of ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1410535s
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION:Antioxidant systems are important factors affecting the oxidation of lipoproteins and thereby the progression of atherosclerotic disease. It has been suggested that physical activity might maintain and promote the antioxidant defence capacity against the oxidative stress. Left ventricular dysfunction (LVDD...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0904146k
更新日期:2009-03-01 00:00:00
abstract::Hand dominance is defined as a proneness to use one hand rather than another in performing the majority of activities and this is the most obvious example of cerebral lateralization and an exclusive human characteristic. Left-handed people comprise 6-14% of the total population, while in Serbia, this percentage is 5-1...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:10.2298/sarh1006387m
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION:A Monteggia lesion is a dislocation of the radial head associated with a fracture with the proximal third of the ulna. It is rare in children and the dislocation of the radial head is often missed at the time of injury. There are a lot of described treatment methods: open reduction of the radial head and r...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1102099v
更新日期:2011-01-01 00:00:00
abstract::Pharmacotherapy of autoimmune thyroid disease (AITD) is complex. Apart from the replacement hormone therapy, antithyroid agents, beta adrenoceptor blockers and other drugs, in regard to the present symptoms, it also includes the administration of glucocorticoids and immunosuppressive agents. Physiological actions of g...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:10.2298/sarh05s1067g
更新日期:2005-10-01 00:00:00
abstract::There is a variety of terms related to the classification of voice disorders still in use. The basic characteristics are discussed. Classification according to Perello, modified by the author, is recommended. On the basis of this classification, the "basic diagnosis" is suggested, with all necessary diagnostic procedu...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:1995-05-01 00:00:00
abstract:INTRODUCTION:Thirty to 50% of patients with chronic hepatitis C (CHC) have one or more extrahepatic manifestations (EHMs) of hepatitis C virus (HCV) infection. OBJECTIVE:The aim of this study was to evaluate the frequency of EHMs and to investigate the efficacy of pegylated interferon (Peg-IFN)-alpha-2a plus ribavirin...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1306320f
更新日期:2013-05-01 00:00:00
abstract::The drugs which are used today in medical treatment of asthma can be divided into two groups. The first group contains corticosteroides, as antiinflammatory agents. The second group contains bronchodilatators, usually used as symptomatic medicaments, and the third group are asthma--profilactics. The mechanism of activ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:1995-06-01 00:00:00
abstract:INTRODUCTION:Diseases of the gastrointestinal system, and especially diseases of esophagus, are a rare cause of sudden unexpected death in any age group. Black esophagus is an acute necrotizing inflammation of the mucosa of the lower parts of esophagus, diffusely affecting its entire circumference. This inflammation co...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1402094n
更新日期:2014-01-01 00:00:00
abstract::Orthopaedic procedures and anaesthesia are not physiological states. To prevent orthopaedic sequelae, laboratory diagnoses are of proven value in preoperative and postoperative complications as well as preoperative diseases. Laboratory analyses have an important contribution to early diagnosis of infection, haemostasi...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:10.2298/sarh0904199d
更新日期:2009-03-01 00:00:00
abstract::In the last two decades the clinical and research focus in psychotic disorders has shifted to first episode psychosis, early detection of the prodromal phase of psychosis and an effective integrated treatment model known as "Early Intervention". The first five years of psychosis that is described as a "critical period...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:2007-11-01 00:00:00
abstract::Inflammatory response in tissue results from a complex network of interactions between inflammatory cells (mast cells, eosinophils, basophils, macrophages) and resident cells belonging to the lung structure (like endothelial cells, fibroblasts, epithelial cells). Among structural cells, endothelial cells play a critic...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:1998-03-01 00:00:00
abstract::Our results of surgery of developmental disorder of the hip (DDH) in older children and adolescents by using the combination of Selter's innominate osteotomy and osteotomy of the superior pubis ramus were presented in this paper, enclosing the period from 1993 to 1995. The study included 11 hips, i.e. 9 patients, aged...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh04s1023b
更新日期:2004-10-01 00:00:00
abstract::The diagnosis of hypertension in patients on chronic haemodialysis is not easy because the blood pressure changes as a consequence of therapy (haemodialysis) and attenuated circadian rhythm of blood pressure is often present. The estimation of representative blood pressure levels is difficult because it is not known w...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0210306p
更新日期:2002-09-01 00:00:00
abstract::In order to standardize language of medicine, it is essential to have a good command of ancient Greek and Latin. We cannot deny a huge impact of ancient Greek medicine on medical terminology. Compounds of Greek origin related to terms for organs, illnesses, inflammations, surgical procedures etc. have been listed as e...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0710606m
更新日期:2007-09-01 00:00:00
abstract:INTRODUCTION:L-asparaginase (L-ASP) is one of the most effective medications for the treatment of acute lymphoblastic leukaemia (ALL) in children, and allergic reactions to the therapy are considered the most significant side effects. OBJECTIVE:The aim of this study was to determine the prevalence and type of allergic...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1112749k
更新日期:2011-11-01 00:00:00
abstract::Bladder cancer is a common form of neoplasia which most often presents histologically as urothelial (transitional cell) carcinoma. In this article we review recent publications dealing with the less common variants of urothelial carcinoma such as tumours that show unusual forms of differentiation or the well know squa...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:2011-09-01 00:00:00
abstract::Subclinical thyroid disease is defined by an abnormally high (subclinical hypothyroidism) or low (subclinical hyperthyroidism) serum thyrotropin (TSH) with peripheral thyroid hormone concentrations within the laboratory reference ranges. Such abnormalities in thyroid function tests are very common in the population an...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:2003-11-01 00:00:00
abstract:UNLABELLED:It is well known and described in literature that cardiac symptoms such as dyspnoea, palpitations and sometimes stenocardiac pain may develop in the course of anaemia. The incidence of electrocardiographic abnormalities varies significantly in different studies ranging from 10-80%. The study is aimed to dete...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract::The frequency and the degree of bronchial hyperreactivity was investigated in 92 patients suffering from chronic obstructive bronchitis. Bronchial reactivity was examgned by the inhalator acetylcholine test, with the use of a 5 mg dose of acetylcholine, diluted in 1 ml of sodium-chloride solution. The pulmonary functi...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::Actual diagnostic sriteria are represented by a large spectar of data proposed by certain authors, so generally accepted protocole does not exist for similar clinical states i.e. asthmatic bronchitis, recurrent bronchitis and bronchial asthma in childhood, there is a different diagnostic terminology. Our clinical expe...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:The obstruction of blood vessels or heart chambers with fat globules, reached by circulation, is fat embolism [1, 2]. Clinical manifestation of the presence of fat emboli in vital organs is Fat Embolism Syndrome (FES). This syndrome is characterized by neurologic, respiratory and cutaneous signs and differ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:INTRODUCTION:The study represents the first investigation of outpatient use of beta lactam antibiotics in Montenegro carried out in accordance with internationally approved methodology (DDD/ATC). OBJECTIVE:The objective of our study was to establish both the scope and overall use of beta lactam antibiotics, and to ass...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0606224d
更新日期:2006-05-01 00:00:00
abstract::Solid and cystic-papillary tumour of the pancreas is a rare neoplasm. About 420 cases seem to have been reported as yet. It appears almost exclusively in young women, although it may appear in males in all ages. This is a tumour of benign or low malignant potential with vary rare invasion of surrounding tissues and or...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::Topics of this report concerns the existing elements of informatics related to education of graduate students of the Medical Faculty in Belgrade. The already used practice of this system makes possible effectiveness and quality in this work. System itself contains quite a few data bases: for students, for teaching stu...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract::This review is a brief overview of recent advances in biology as well as in potential clinical application of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF). Biologically active rhGM-CSF is a recombinant human protein expressed in Escherichia coli. GM-CSF is produced by nontransformed (T...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:1993-08-01 00:00:00