Abstract:
BACKGROUND:The incidence of ventricular fibrillation (VF) as the presenting rhythm in out-of-hospital cardiac arrest (OHCA) is declining, whereas pulseless electrical activity (PEA) is increasing. This changing epidemiology has occurred concomitant with an increase in beta-blocker use. AIMS:The aim of this study was to measure the association of beta-blocker use among prehospital cardiac arrest patients with PEA versus VF as presenting rhythm. MATERIALS AND METHODS:In this retrospective cohort study, records of all OHCA patients presenting to a single municipal hospital between 1 January 2001 and 31 December 2006 were reviewed. Age, sex, race, first documented rhythm, estimated down time, presence of bystander CPR, return of spontaneous circulation, beta-blocker use, and comorbid illnesses were noted. A Mantel-Haenzel chi-square was computed to describe the association between beta-blocker use and PEA, compared to beta-blocker use and VF. A sensitivity analysis was also performed to account for missing data, misclassification of beta-blocker use, misclassification of initial rhythm, confounding by unknown factors, and random error. RESULTS:After exclusion of patients with asystole and patients in whom beta-blocker use was unclear/unknown, a cohort of 179 arrests was evaluated. The odds ratio for beta-blocker use among PEA versus VF patients was 3.7 (95% CI 1.9-7.2), and probabilistic adjustment for exposure and outcome misclassification, confounding, and random error increased the odds ratio to 5.0 (95% CI 1.1-31.0). CONCLUSIONS:There appears to be an association between beta-blockers and the changing epidemiology of arrest rhythms, which may account for the increasing incidence of PEA and concomitant decrease in VF.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Youngquist ST,Kaji AH,Niemann JTdoi
10.1016/j.resuscitation.2007.08.022subject
Has Abstractpub_date
2008-03-01 00:00:00pages
376-80issue
3eissn
0300-9572issn
1873-1570pii
S0300-9572(07)00487-Xjournal_volume
76pub_type
杂志文章相关文献
RESUSCITATION文献大全abstract::We studied cardiovascular changes and neurologic outcome at 72 h in 42 healthy dogs after normothermic ventricular fibrillation cardiac arrest (no blood flow) of 7.5, 10, or 12.5 min duration, reversed by standard external cardiopulmonary resuscitation (CPR) (< or = 10 min) and followed by controlled ventilation to 20...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(93)90003-9
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVE:Gastric inflation (GI) is a significant issue when ventilation is performed on unprotected airways. DESIGN:Experimental analysis on the respiratory effects of hose extended bag-valve ventilation devices designed to reduce inspiratory pressure and flow. SETTING:Laboratory with lung/oesophageal sphincter simu...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2008.02.022
更新日期:2008-08-01 00:00:00
abstract::The Royal College of Anaesthetists, the Royal College of Physicians, the Intensive Care Society and the Resuscitation Council (UK) have published new resuscitation standards. The document provides advice to UK healthcare organisations, resuscitation committees and resuscitation officers on all aspects of the resuscita...
journal_title:Resuscitation
pub_type: 指南,杂志文章,实务指引
doi:10.1016/j.resuscitation.2004.11.001
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:Pneumonia is the most common infectious complication of drowning. Pneumonia is potentially life threatening and should be treated by effective antibiotic therapy. However the risk factors, microbiological causes, diagnostic approach and appropriate therapy for pneumonia associated with drowning are not well des...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.08.023
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:We evaluated the association between nifekalant or amiodarone on hospital admission and in-hospital mortality for cardiac arrest patients with persistent ventricular fibrillation on hospital arrival. METHODS:This was a retrospective cohort study using the Japanese Diagnosis Procedure Combination inpatient d...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2016.08.017
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:Conflicting data exists regarding the association between sex and mortality in adults with in-hospital (IHCA) and out-of-hospital cardiac arrest (OHCA). We therefore conducted a meta-analysis to investigate the association between sex and mortality in adults with IHCA and OHCA. METHODS:We systematically sea...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/j.resuscitation.2020.07.031
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Measuring survival from sudden out-of-hospital cardiac arrest (OOH-CA) is often used as a benchmark of the quality of a community's emergency medical service (EMS) system. The definition of OOH-CA survival rates depends both upon the numerator (surviving cases) and the denominator (all cases). PURPOSE:The p...
journal_title:Resuscitation
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/j.resuscitation.2004.02.007
更新日期:2004-07-01 00:00:00
abstract::Because closed chest cardiopulmonary resuscitation (CCCPR) achieve restoration of spontaneous circulation (ROSC) in less than 50% of cases, and because of the apparent physiological superiority of open-chest cardiopulmonary resuscitation (OCCPR), we evaluated OCCPR in out-of hospital cardiac arrest in cases who did no...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(97)00041-5
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:Pulseless electrical activity is an important cause of cardiac arrest. Our purpose was to determine if induction of hypothermia with a cold perfluorocarbon-based total liquid ventilation (TLV) system would improve resuscitation success in a swine model of asphyxial cardiac arrest/PEA. METHODS:Twenty swine w...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2009.11.018
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Therapeutic hypothermia improves neurologic outcomes in patients resuscitated from cardiac arrest due to ventricular fibrillation. However, its role in patients with cardiac arrest due to non-shockable rhythms (pulseless electrical activity (PEA) and asystole) is unclear. We hypothesized that therapeutic hyp...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.08.005
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate whether GlideScope(®) is an effective and acceptable method for the removal of a hypopharyngeal foreign body. METHODS:This was a prospective study conducted in 28 first year emergency residents with little prior airway management experience. Participants extracted hypopharyngeal ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2012.02.032
更新日期:2012-10-01 00:00:00
abstract:AIM:To describe the cerebral blood flow velocity pattern and investigate cerebral autoregulation using transcranial Doppler ultrasonography (TCD) following a global hypoxic-ischaemic (HI) event in children. METHODS:This was a prospective, observational study in a quaternary-level paediatric intensive care unit. Intuba...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2018.02.005
更新日期:2018-05-01 00:00:00
abstract::We report the first case of amitriptyline toxicity treated with intravenous fat emulsion (IFE). Toxicity was manifested as vasopressor-refractory haemodynamic instability despite standard therapy. Our patient recovered with no adverse effects noted. ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2010.04.009
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:It is still under debate whether a period of cardiopulmonary resuscitation should be performed prior to rhythm analysis for defibrillation for out of hospital cardiac arrests (OHCA). This study compared outcomes of OHCA treated by "compression first" (CF) versus "analyze first" (AF) strategies in an Asian co...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2012.01.009
更新日期:2012-07-01 00:00:00
abstract::Cardiac ischemia can present as distinctive clinical syndromes such as acute myocardial infarction, cardiogenic shock, sudden cardiac arrest or chronic congestive heart failure. All of the clinical syndromes share common pathophysiological events including reduction of cardiac output and systemic oxygen delivery (DO2)...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/0300-9572(94)90065-5
更新日期:1994-12-01 00:00:00
abstract:AIM:This study aimed to investigate the effects of dispatcher-initiated telephone cardiopulmonary resuscitation (TCPR) in Japan using a nationwide population-based registry. METHODS:Adult Japanese patients with out-of-hospital cardiac arrest (OHCA; n = 582,483, age ≥18 years) were selected from a nationwide Utstein-st...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.08.031
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:To describe our outcomes using thrombolysis during the cardiopulmonary resuscitation (CPR) of patients in cardiorespiratory arrest (CA) caused by fulminant pulmonary embolism (FPE). DESIGN:A case series. SETTING:Intensive care units of a district hospital and a referral centre. PATIENTS:Six patients that s...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(01)00384-7
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Efficiently performed basic life support (BLS) after cardiac arrest is proven to be effective. However, cardiopulmonary resuscitation (CPR) is strenuous and rescuers' performance declines rapidly over time. Audio-visual feedback devices reporting CPR quality may prevent this decline. We aimed to investigate ...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2013.10.028
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Cardiac arrest (CA) without return of spontaneous circulation can be treated with veno-arterial extracorporeal membrane oxygenation (vaECMO) implemented surgically or percutaneously. We performed a study assessing time for vaECMO percutaneous cannulation in the catheterization laboratory. METHODS:Single-cen...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2017.11.057
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND/AIM:The relationship between echocardiographic findings of intra-arrest TEE and resuscitation outcomes was not clearly identified. We assessed echocardiographic findings observed in intra-arrest TEE and its relationship with resuscitation outcomes. METHODS:This retrospective observational study analysed adu...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2020.06.035
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:The Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) is an emergency care and treatment planning (ECTP) process, developed to offer a patient-centred approach to deciding about and recording treatment recommendations. Conversations between clinicians and patients or their representatives a...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2021.01.013
更新日期:2021-01-19 00:00:00
abstract:UNLABELLED:The aim of this study was to characterize gene expression following hemorrhagic shock and resuscitation with emphasis on the differences between various resuscitation strategies. METHODS:Male Sprague Dawley rats (n = 25; 5/group) were subjected to a three stage hemorrhage and resuscitated as follows: (1) sh...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(02)00095-3
更新日期:2002-08-01 00:00:00
abstract:UNLABELLED:Cardiac arrest presenting as pulseless electrical activity (PEA) currently has a very low survival rate. Many of the conditions underlying PEA (cardiac tamponade, hypovolemia, and pulmonary embolus) are associated with specific cardiac ultrasound findings. The aim of this study was to evaluate a rapid cardia...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2005.04.007
更新日期:2005-10-01 00:00:00
abstract::In acute cerebrovascular accidents the uptake of lactate by the brain tissue is enhanced, possibly in an attempt to buffer the increased local lactic acidosis. In this paper the results obtained by the administration of the lactate in 78 cases of hyperventilatory syndromes secondary to acute brain injuries, and the bi...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(78)90009-6
更新日期:1978-01-01 00:00:00
abstract::This study compares the retention of basic life support (BLS) skills after 6 and 12 months by lay persons trained either in a conventional manner, or using a staged approach. Three classes, each of 2h, were offered to volunteers over a period of 4 months. For the conventional group, the second and third classes consis...
journal_title:Resuscitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2003.12.014
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:The incidence of pulseless electrical activity (PEA) as a presenting rhythm during cardiac arrest is increasing. The current animal models of PEA arrest, post-countershock or total asphyxiation, unreliably generate PEA for a specific time period. Neither of these models predictably generate pseudo-PEA. The p...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2008.03.011
更新日期:2008-08-01 00:00:00
abstract:INTRODUCTION:We studied how effectively a mixed group of helpers could ventilate a manikin with a new rescue breathing device after a short period of instruction. The device consists of a mouthcap, a "glossopalatinal tube" (GPT) reaching between tongue and palate and a connector for a bag, ventilator or the rescuers mo...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(03)00205-3
更新日期:2003-11-01 00:00:00
abstract:AIM:Various methods, including self-instruction, have been used to try to improve the acquisition of basic life support skills. This is a preliminary report of the effectiveness of a web-based self-training program for BLS and the use of an AED. METHODS:Sixteen volunteers completed on-line training in their own time o...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2007.05.014
更新日期:2007-12-01 00:00:00
abstract:AIM:To investigate the impact of a history of diabetes mellitus on the neurologic outcome in comatose survivors of cardiac arrest of cardiac origin treated with mild hypothermia. METHODS:A prospective observational study was performed between September 2003 and July 2008. Eighty comatose survivors of cardiac arrest of...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2009.04.041
更新日期:2009-08-01 00:00:00
abstract::Prompt and effective cardiopulmonary resuscitation (CPR) is the first link in the chain of survival following cardiac arrest. We assessed a new device, the CPR-Ezy (Medteq Innovations Pty Ltd., Brisbane, Australia), to aid timing and effectiveness of external cardiac compressions (ECC), by 32 subjects who had prior co...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(02)00049-7
更新日期:2002-07-01 00:00:00