Early detection of adverse drug events within population-based health networks: application of sequential testing methods.

abstract：PURPOSE:The Vaccine Safety Datalink (VSD) Project conducts near real-time vaccine safety surveillance using sequential analytic methods. Timely surveillance is critical in identifying potential safety problems and preventing additional exposure before most vaccines are administered. For vaccines that are administered d...

journal_title：Pharmacoepidemiology and drug safety

authors： Greene SK,Kulldorff M,Yin R,Yih WK,Lieu TA,Weintraub ES,Lee GM

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:Because preapproval clinical trials typically exclude pregnant women, the evidence on drug safety during pregnancy required to inform drug labeling must come from postapproval controlled observational studies. Common designs have included pregnancy registries and case-control studies. Recently, pregnancy cohort...

journal_title：Pharmacoepidemiology and drug safety

authors： Huybrechts KF,Bateman BT,Hernández-Díaz S

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:Observational pharmacoepidemiological studies can provide valuable information on the effectiveness or safety of interventions in the real world, but one major challenge is the existence of unmeasured confounder(s). While many analytical methods have been developed for dealing with this challenge, they appear u...

journal_title：Pharmacoepidemiology and drug safety

authors： Zhang X,Faries DE,Li H,Stamey JD,Imbens GW

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:A case-control study is the most powerful design to test the risk of specific congenital malformations associated with a specific drug. However, malformation registries often lack non-malformed controls. For the Dutch EUROCAT, we collected a non-malformed control group: the 'Healthy Pregnant'. The aim of this s...

journal_title：Pharmacoepidemiology and drug safety

authors： Jentink J,Zetstra-van der Woude AP,Bos J,de Jong-van den Berg LT

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Administrative claim databases are increasingly being used to study the safety of medication exposures during pregnancy. These studies are restricted to live births due to a reliance on algorithms for estimating gestational age that are based on codes associated with live delivery. Conditioning on live birth ma...

journal_title：Pharmacoepidemiology and drug safety

authors： Suarez EA,Landi SN,Conover MM,Jonsson Funk M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The Epidemiologic Registry of Cystic Fibrosis (ERCF) was a multicentre, longitudinal follow-up project of cystic fibrosis patients enrolled at some 200 centres in nine European countries between 1994 and 1999. PURPOSE:We aimed to assess and improve the quality of a subset of data from the ERCF relating to s...

journal_title：Pharmacoepidemiology and drug safety

authors： Strobl J,Enzer I,Bagust A,Haycox A,Smyth R,Ashby D,Walley T

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:In pharmacoepidemiology, one of the main concerns is analysis of drug exposure time. However, in real-life settings, patient's behavior is complex and characterized by drug exposure dynamics. Multi-state models allow assessing the probabilities of various patterns, instead of just continuous use and/or disconti...

journal_title：Pharmacoepidemiology and drug safety

authors： Boucherie Q,Pauly V,Frauger E,Thirion X,Pradel V,Micallef J

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Risk assessment for natural health products (NHPs) may not be evaluated similarly to therapeutic products by Health Canada in terms of notification of harms to consumers and health professionals. In this descriptive study, we evaluated risk communications (RCs) issued by Health Canada for NHPs and for therapeut...

journal_title：Pharmacoepidemiology and drug safety

authors： Bateman J,Charrois TL,Gardiner P,Vohra S

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To investigate pattern and extent of adverse drug reactions (ADRs) associated with AEDs and to identify safer options for treatment of epilepsy. METHOD:Study was a retrospective, cross-sectional survey. Data from patients with epilepsy at the out-patient and in-patient of Neurology Department was collected in ...

journal_title：Pharmacoepidemiology and drug safety

authors： S RB,Narayan SS,Sharma GR,Rodrigues RJ,Kulkarni C

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To optimize the efficiency of signal detection by maximizing the proportion of true positive (TP) signals among signals detected by a disproportionality algorithm. METHODS:We compared 176 different combinations of stratification factors, sex (S), age (A), region (R) and year of report (Y), and cut-off values o...

journal_title：Pharmacoepidemiology and drug safety

authors： Van Holle L,Bauchau V

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:The Dietary Supplements Information Expert Committee (DSI-EC; the Committee) of the United States Pharmacopeial Convention (USP) reviews safety profiles of dietary supplements before development of USP-National Formulary (USP-NF) quality monographs. Because the veracity of dietary supplement adverse event repor...

journal_title：Pharmacoepidemiology and drug safety

authors： Gardiner P,Sarma DN,Low Dog T,Barrett ML,Chavez ML,Ko R,Mahady GB,Marles RJ,Pellicore LS,Giancaspro GI

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:The use of prescription opioid analgesics has been increasing over the last few decades in Australia. In particular, oxycodone and fentanyl have increased substantially. We examined the gender and age trends in the prescribing of subsidised opioid analgesics in the Australian population for non-palliative care ...

journal_title：Pharmacoepidemiology and drug safety

authors： Hollingworth SA,Gray PD,Hall WD,Najman JM

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Laboratory technicians, laboratory supervisors, decontamination/remediation workers, and environmental investigators are at increased risk for repeated occupational exposure to Bacillus anthracis. In 2002, the Advisory Committee on Immunization Practices (ACIP) recommended pre-exposure vaccination for these ...

journal_title：Pharmacoepidemiology and drug safety

authors： Fowler GL,Baggs JM,Weintraub ES,Martin SW,McNeil MM,Gust DA

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To determine patterns of United Arab Emirates (UAE) citizen herbal medicine taking. METHODS:Questionnaire survey of UAE citizens attending a primary healthcare clinic in Abu Dhabi. RESULTS:Three hundred and thirty surveys were analysed. Seventy-six per cent (250/330) had previously used herbal products, and o...

journal_title：Pharmacoepidemiology and drug safety

authors： AlBraik FA,Rutter PM,Brown D

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:We aimed to investigate the association between psychotropic treatment and risk of burn injury in individuals with mental illness. METHODS:A nested case-control study was conducted by using the National Health Insurance Research Database in Taiwan. A total of 3187 cases with burn injury under International Cla...

journal_title：Pharmacoepidemiology and drug safety

authors： Chang CM,Wu KY,Chiu YW,Wu HT,Tsai YT,Chau YL,Tsai HJ

更新日期：2016-08-01 00:00:00

abstract：:Adverse drug reaction surveillance conducted by the US Federal Food and Drug Administration (FDA) is important for detecting new safety information about pharmaceuticals. FDA has sought to stimulate reporting of reactions by practitioners and manufacturers. Over the five years from 1989 to 1993, reporting more than do...

journal_title：Pharmacoepidemiology and drug safety

authors： Faich GA

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:The objective of this study was to quantify rates of adverse events in a high-risk multi-morbid population of institutionalized patients with Alzheimer's disease (AD). METHODS:We conducted a retrospective cohort study among nursing home residents diagnosed with AD and psychosis during January 1998 to October 1...

journal_title：Pharmacoepidemiology and drug safety

authors： Oliveria SA,Liperoti R,L'italien G,Pugner K,Safferman A,Carson W,Lapane K

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to estimate the prevalence of first-generation antipsychotics (FGA) prescribed for treatment of psychiatric and neurological conditions and use of benztropine to reduce extrapyramidal side effects (EPS) by patient race/ethnicity in a nationally representative sample of adult outpatient...

journal_title：Pharmacoepidemiology and drug safety

authors： Cook TB,Reeves GM,Teufel J,Postolache TT

更新日期：2015-11-01 00:00:00

abstract：:When a biological hypothesis of causal effect can be inferred, the hypothesis can sometimes be tested in the selfsame database that gave rise to the study data from which the hypothesis grew. Valid testing happens when the inferred biological hypothesis has scientific implications that predict new relations between ob...

journal_title：Pharmacoepidemiology and drug safety

authors： Walker AM

更新日期：2010-05-01 00:00:00

abstract：UNLABELLED:Computerized hospital databases are used for clinical and economic research. In France, the hospital administrative database, Programme de médicalisation des systèmes d'information (PMSI), could be an interesting means for identifying cases of abuse and dependence in hospitals. PURPOSE:To assess the capabil...

journal_title：Pharmacoepidemiology and drug safety

authors： Daveluy A,Miremont-Salamé G,Kostrzewa A,Couret A,Lacoin L,Lecomte C,Moore N,Gilleron V,Haramburu F

更新日期：2012-12-01 00:00:00

abstract：:Recent studies have shown that modern (third generation), oral contraceptives (OC) are associated with an increased incidence of venous thromboembolic disease compared to older (second generation), OC. It is not known, however, whether this association is also true for arterial thrombosis, in particular myocardial inf...

journal_title：Pharmacoepidemiology and drug safety

authors： Dunn NR,Thorogood M,de Caestecker L,Mann RD

更新日期：1997-07-01 00:00:00

abstract：PURPOSE:Quantitative benefit-risk (B-R) assessments are used to characterize treatment by combining key benefits and risks into a single metric but have historically been done for the "average" patient. Our aim was to conduct an individualized assessment for the oral antiplatelet vorapaxar by combining trial and real-w...

journal_title：Pharmacoepidemiology and drug safety

authors： Pinto CA,Tervonen T,Marsh K,Lambrelli D,Schultze A,Tershakovec A,Hyacinthe J,Prawitz T,Hammad TA

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:To determine healthcare claim patterns associated using nonsteroidal anti-inflammatory drugs (NSAIDs) for rheumatoid arthritis (RA). METHODS:The CADEUS study randomly identified NSAID users within the French health insurance database. One-year claims data were extracted, and NSAID indication was obtained from ...

journal_title：Pharmacoepidemiology and drug safety

authors： Bernard MA,Bénichou J,Blin P,Weill A,Bégaud B,Abouelfath A,Moore N,Fourrier-Réglat A,CADEUS Team.

更新日期：2012-06-01 00:00:00

abstract：:The following article from Pharmacoepidemiology and Drug Safety, “Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery” by F. Krummenauer, S. Kurz and H.B. Dick, published online on July 11 2006 inWiley Online Library (wileyonlinelibrary.com), has...

journal_title：Pharmacoepidemiology and drug safety

authors：

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To conduct a systematic review of current evidence regarding the use of health information technology (HIT) interventions to improve drug monitoring in ambulatory care. METHODS:We searched PubMed, CINAHL, the Cochrane Library, and other computerized databases from 1 January 1998 to 30 June 2008 using the key w...

journal_title：Pharmacoepidemiology and drug safety

authors： Hayward GL,Parnes AJ,Simon SR

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:To determine the validity of pregnancy variables recorded in administrative databases of Quebec using patient medical charts as the gold standard among asthmatic pregnant women. METHODS:Three administrative databases were linked and provided information on maternal, pregnancy and infant characteristics for 726...

journal_title：Pharmacoepidemiology and drug safety

authors： Vilain A,Otis S,Forget A,Blais L

更新日期：2008-04-01 00:00:00

abstract：:Schizophrenia is a life-threatening disease associated with mortality rates that are two to three times higher than those expected/observed in the general population. It is associated with high levels of suicide, particularly in young male patients soon after diagnosis. Delays in treating schizophrenia could contribut...

journal_title：Pharmacoepidemiology and drug safety

authors： Auquier P,Lançon C,Rouillon F,Lader M

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:We evaluated national outpatient antimicrobial prescription trends in relation to the first United States case of inhalational anthrax due to the intentional delivery of Bacillus anthracis (B. anthracis) spores. METHODS:We queried IMS HEALTH's National Prescription Audit Plus7 database for two 6-month periods ...

journal_title：Pharmacoepidemiology and drug safety

authors： Shaffer D,Armstrong G,Higgins K,Honig P,Coyne P,Boxwell D,Beitz J,Leissa B,Murphy D

更新日期：2003-04-01 00:00:00

abstract：:There is an increasing reliance on databases of healthcare records for pharmacoepidemiology and other medical research, and such resources are often accessed over a long period of time so it is vital to consider the impact of changes in data, access methodology and the environment. The authors discuss change in commun...

journal_title：Pharmacoepidemiology and drug safety

authors： Bourke A,Bate A,Sauer BC,Brown JS,Hall GC

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:Epidemiological data on adhesion-related complications following intra-abdominal surgery are limited. We tested the accuracy of recording of these surgeries and complications within The Health Improvement Network (THIN), a primary care database within the UK. METHODS:Individuals within THIN from 1995 to 2011 w...

journal_title：Pharmacoepidemiology and drug safety

authors： Scott FI,Mamtani R,Haynes K,Goldberg DS,Mahmoud NN,Lewis JD

更新日期：2016-04-01 00:00:00