Abstract:
OBJECTIVES:To explore whether the predictive power of mid-life ECG abnormalities and conventional cardiovascular risk factors for future stroke change over a 30-year follow-up period, and whether a repeated examination improves their predictive power. DESIGN AND SETTING:Longitudinal population-based study. PARTICIPANTS:2,322 men aged 50 years, with a follow-up period of 30 years. 1,221 subjects were re-examined at age 70 years MAIN OUTCOME MEASURE:Risk for fatal and non-fatal stroke during three decades of follow-up. Investigations included resting ECG and traditional cardiovascular risk factors. RESULTS:When measured at age 50 years, ST segment depression and T wave abnormalities, together with ECG-left ventricular hypertrophy, were of importance only during the first 20 years, but regained importance when re-measured at age 70 years. Blood pressure was a significant predictor for stroke over all three decades of follow-up. In elderly people only, there is evidence that apolipoprotein A1 may protect from future stroke. CONCLUSION:Mid-life values for blood pressure and ECG abnormalities retain their predictive value over long follow-up periods even though they improved in predictive power when re-measured in elderly people. Despite lower prevalence, ECG abnormalities had greater impact at age 50 years than at age 70 years. By contrast, apolipoprotein A1 was protective for future stroke only at age 70 years.
journal_name
J Epidemiol Community Healthjournal_title
Journal of epidemiology and community healthauthors
Möller CS,Häggström J,Zethelius B,Wiberg B,Sundström J,Lind Ldoi
10.1136/jech.2006.048074subject
Has Abstractpub_date
2007-08-01 00:00:00pages
704-12issue
8eissn
0143-005Xissn
1470-2738pii
61/8/704journal_volume
61pub_type
杂志文章abstract:STUDY OBJECTIVE:To determine the incidence of cancer among homeless men in Glasgow. DESIGN:Descriptive study of cancer incidence in a defined, though individually unidentifiable, population cohort. SETTING:Glasgow and the West of Scotland Region. PARTICIPANTS:Male residents of 10 hostels for the single homeless in G...
journal_title:Journal of epidemiology and community health
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doi:10.1136/jech.51.6.668
更新日期:1997-12-01 00:00:00
abstract:STUDY OBJECTIVE:To develop a self administered Chinese (mainland) version of the Short-Form Health Survey (SF-36) for use in health related quality of life measurements in China. DESIGN:A three stage protocol was followed including translation, tests of scaling construction and scoring assumptions, validation, and nor...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.57.4.259
更新日期:2003-04-01 00:00:00
abstract::In epidemiological studies the diagnosis of a past history of myocardial infarction is made from the answer to a single question: "Have you ever had a severe pain across the front of your chest lasting for half an hour or more?" Two additional questions, which form an optional part of the London School of Hygiene and ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.42.2.116
更新日期:1988-06-01 00:00:00
abstract:STUDY OBJECTIVES:To compare in-hospital mortality for acute myocardial infarction (AMI) between metropolitan and non-metropolitan hospitals after adjustment for patients' severity; to examine the role of the use of effective cardiac medications in the possible mortality difference between these types of hospital. DESI...
journal_title:Journal of epidemiology and community health
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doi:10.1136/jech.54.8.590
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Neighbourhood social fragmentation and socioeconomic deprivation seem to be associated with suicide mortality. However, results are inconclusive, which might be because dynamics in the social context are not well-represented by administratively bounded neighbourhoods at baseline. We used individualised neigh...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2019-212699
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Studies suggest that racial discrimination impacts health via biological dysregulation due to continual adaptation to chronic psychosocial stress. Therefore, quantifying chronicity is critical for operationalising the relevant aetiological exposure and hence maximising internal validity. Using one of the mos...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2018-211230
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To explore attitudes to quitting smoking and experience of smoking cessation among Bangladeshi and Pakistani ethnic minority communities. DESIGN:Qualitative study using community participatory methods, purposeful sampling, interviews and focus groups, and a grounded approach to data generation and analysis. ...
journal_title:Journal of epidemiology and community health
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更新日期:2006-05-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.55.5.323
更新日期:2001-05-01 00:00:00
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journal_title:Journal of epidemiology and community health
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doi:10.1136/jech-2015-206508
更新日期:2016-08-01 00:00:00
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journal_title:Journal of epidemiology and community health
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更新日期:2011-04-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.086074
更新日期:2010-08-01 00:00:00
abstract::Factors affecting the attendance at primary health care clinics in Lagos were studied at Oguntolu Clinic and Randle Road Health Centre among 120 Nigerian children. The level of immunisation was a measure of the frequency (regularity) of attendance at the clinics. Certain socioeconomic, psychological, and demographic f...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.36.4.310
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:Diagnosis of cancer through emergency presentation is associated with poorer prognosis. While reductions in emergency presentations have been described, whether known sociodemographic inequalities are changing is uncertain. METHODS:We analysed 'Routes to Diagnosis' data on patients aged ≥25 years diagnosed ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech-2017-210371
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to quantify mortality after elective repair of abdominal aortic aneurysm (AAA) in England, and to compare English case fatality rates (CFRs) with those reported in the literature. PATIENTS AND METHODS:English Hospital Episode Statistics (HES) for the financial years 1998/9 to 200...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech.2006.047001
更新日期:2007-03-01 00:00:00
abstract:STUDY OBJECTIVE:The aim was to determine whether induced abortions could increase the risk of secondary infertility. DESIGN:This was a case-control study; cases were women with secondary infertility, individually matched to two controls who were currently pregnant. Each participant was interviewed by one of two medica...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.47.1.36
更新日期:1993-02-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.42.3.209
更新日期:1988-09-01 00:00:00
abstract::Prompted by my participation in the People's Climate March held in New York City on 21 September 2014, as part of the 'Harvard Divest' contingent, in this brief essay I reflect on the late 20th century development of--and debates over--the necessity of ecological thinking in epidemiology, and also the still limited en...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2014-205027
更新日期:2015-08-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2003.010702
更新日期:2005-01-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2005.042838
更新日期:2006-06-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,随机对照试验
doi:10.1136/jech-2011-200689
更新日期:2012-08-01 00:00:00
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更新日期:1988-09-01 00:00:00
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journal_title:Journal of epidemiology and community health
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doi:10.1136/jech-2013-202449
更新日期:2014-07-01 00:00:00
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journal_title:Journal of epidemiology and community health
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doi:10.1136/jech.2010.120154
更新日期:2012-09-01 00:00:00
abstract::Principal component analysis (PCA) is frequently adopted for creating socioeconomic proxies in order to investigate the independent effects of wealth on disease status. The guidelines and methods for the creation of these proxies are well described and validated. The Demographic and Health Survey, World Health Survey ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2017-209119
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Underserved women (rural, minority or poor) are disproportionally diagnosed with late-stage cervical cancer, indicative of inadequate access to, and use of, preventative healthcare. The Institute of Medicine (IOM) has proposed that nurse practitioners (NP) can address provider shortages among underserved pop...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech-2018-210709
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Alcohol misuse, especially binge drinking in young people, and alcoholic liver disease are major public health concerns. However, alcohol misuse in older people is underestimated and often goes undetected. OBJECTIVE:To document alcohol consumption and clinical presentation of alcohol misuse in hospital inpa...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2005.043653
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Although a known risk factor for several respiratory diseases, the relationship between cooking smoke and tuberculosis has not been conclusively established. Hence, a case-control study was conducted among adult women of Chandigarh Union Territory in India. METHODS:Physician-diagnosed cases of sputum positi...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2010.115840
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:We examined whether higher effort-reward imbalance (ERI) and lower job control are associated with exit from the labour market. METHODS:There were 1263 participants aged 50-74 years from the English Longitudinal Study on Ageing with data on working status and work-related psychosocial factors at baseline (w...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2014-205148
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:The prevalence of diagnosed diabetes among different ethnic groups and the influence of deprivation on the prevalence of diabetes among Māori and New Zealand Europeans was investigated. METHODS:This was a cross-sectional survey on all patients registered with 10 practices in the Rotorua General Practice Gro...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.078873
更新日期:2009-05-01 00:00:00
abstract:STUDY OBJECTIVE:The main cause of breast cancer remains unknown. Numerous causal factors or predisposing conditions have been proposed, but account for only a small percentage of the total disease. The current search for multiple causes is unavailing. This report explores whether any single aetiological agent may be re...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech.54.11.851
更新日期:2000-11-01 00:00:00