Abstract:
:The heparin-induced self-aggregation behaviours of four repeat peptides (R1-R4) in an acidic solution (pH = 4.5) were investigated by fluorescence and circular dichroism (CD) measurements and compared with those in a neutral solution (pH = 7.5). In contrast with the self-aggregation-resistive behaviours of the R1 and R4 repeat peptides in the neutral solution, the R4 peptide formed a filament similarly to the R2 and R3 peptides in the acidic solution, whereas the R1 peptide still showed resistive behaviour for filament formation. This is the first report on the markedly different self-aggregation behaviours of the first and fourth repeat peptides on tau microtubule-binding domain.
journal_name
J Biochemjournal_title
Journal of biochemistryauthors
Mizushima F,Minoura K,Tomoo K,Sumida M,Taniguchi T,Ishida Tdoi
10.1093/jb/mvm099subject
Has Abstractpub_date
2007-07-01 00:00:00pages
49-54issue
1eissn
0021-924Xissn
1756-2651pii
mvm099journal_volume
142pub_type
杂志文章abstract::In the preceding paper [Maita, T., Miyanishi, T., Matsuzono, K., Tanioka, Y., & Matsuda, G. (1991) J. Biochem. 110, 68-74], we reported the amino-terminal 837-residue sequence of the heavy chain of adult chicken pectoralis muscle myosin. This paper describes the carboxyl terminal 1,097-residue sequence and the linkage...
journal_title:Journal of biochemistry
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更新日期:1991-07-01 00:00:00
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journal_title:Journal of biochemistry
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更新日期:1998-10-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
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更新日期:1998-09-01 00:00:00
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journal_title:Journal of biochemistry
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journal_title:Journal of biochemistry
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journal_title:Journal of biochemistry
pub_type: 杂志文章
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更新日期:2003-03-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a135400
更新日期:1985-11-01 00:00:00
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journal_title:Journal of biochemistry
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更新日期:1977-08-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
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更新日期:1993-04-01 00:00:00
abstract::Autotaxin (ATX) is an ecto-enzyme responsible for lysophosphatidic acid (LPA) production in blood. ATX is present in various biological fluids such as cerebrospinal and seminal fluids and accounts for bulk LPA production in these fluids. ATX is a member of the nucleotide pyrophosphatase/phosphodiesterase (NPP) family ...
journal_title:Journal of biochemistry
pub_type: 杂志文章,评审
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更新日期:2010-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:1980-05-01 00:00:00
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journal_title:Journal of biochemistry
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更新日期:2000-06-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a132727
更新日期:1980-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:1999-12-01 00:00:00
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journal_title:Journal of biochemistry
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更新日期:1979-02-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
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更新日期:1984-06-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a122695
更新日期:1989-04-01 00:00:00
abstract::The juvenile visceral steatosis (JVS) mouse is a novel mutant animal for studying systemic carnitine deficiency. The importance of the model has been pointed out in carnitine-deficient cardiac hypertrophy, since cardiomyopathy has been often improved after oral carnitine therapy in human systemic carnitine deficiency....
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pub_type: 杂志文章
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更新日期:1996-03-01 00:00:00