Influence of thyroxine treatment on thyroid size and anti-thyroid peroxidase antibodies in Hashimoto's thyroiditis.

abstract：:Severe pituitary Cushing's disease of sudden onset after 18 years of unsuccessful treatment for a previously non-functioning chromophobe adenoma is described in a middle-aged woman. Initial presentation with symptoms of optic nerve compression had been preceded by two years of amenorrhoea. Transfrontal resection of a ...

journal_title：Clinical endocrinology

authors： Vaughan NJ,Laroche CM,Goodman I,Davies MJ,Jenkins JS

更新日期：1985-02-01 00:00:00

abstract：:The age-dependent decline of the gonadal and somatotopic axis has been causally linked to frailty in the elderly by their effects on muscle mass and bone mineral density. However, for healthy men data on serum oestrogens and androgens, as well as IGF-1, as a common outcome measure covering the whole adult age range ar...

journal_title：Clinical endocrinology

authors： Leifke E,Gorenoi V,Wichers C,Von Zur Mühlen A,Von Büren E,Brabant G

更新日期：2000-12-01 00:00:00

abstract：:It has been reported that administration of nomifensine (Nom) or of L-dopa + carbidopa (L-dopa + Carb) potentiates central dopaminergic tonus, resulting in decreased prolactin (PRL) secretion. It has been proposed that these drugs would help to discriminate patients with PRL-secreting pituitary tumours from those with...

journal_title：Clinical endocrinology

authors： Moriondo P,Travaglini P,Nissim M,Faglia G

更新日期：1980-12-01 00:00:00

abstract：:We have studied the inositol phospholipid turnover response to thyrotrophin-releasing hormone (TRH) gonadotrophin-releasing hormone (GnRH) and arginine vasopressin (AVP) in five corticotroph and six somatotroph pituitary adenomas. GnRH (100 nM) increased inositol phospholipid turnover in five of five somatotroph adeno...

journal_title：Clinical endocrinology

authors： Levy A,Lightman SL,Hoyland J,Mason WT

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to group patients with MODY (maturity-onset diabetes of the young) according to the genetic alterations underlying the disease and to investigate their clinical characteristics. PATIENTS AND METHODS:Molecular analysis of GCK (MODY2), HNF-1alpha (MODY3), HNF-4alpha (MODY1) and HNF-1b...

journal_title：Clinical endocrinology

authors： Estalella I,Rica I,Perez de Nanclares G,Bilbao JR,Vazquez JA,San Pedro JI,Busturia MA,Castaño L,Spanish MODY Group.

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:The diagnosis of growth hormone deficiency (GHD) in adults is established through growth hormone (GH) stimulation testing, which is often complex, expensive, time-consuming and may be associated with adverse side effects. The decision to perform GH provocative testing is influenced by clinical findings, medic...

journal_title：Clinical endocrinology

authors： Zgaljardic DJ,Guttikonda S,Grady JJ,Gilkison CR,Mossberg KA,High WM Jr,Masel BE,Urban RJ

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:ACTH-producing non-pituitary tumours are often associated with altered precursor processing, particularly in the most aggressive ones. Since placental tissue is characterized by its ability to express the proopiomelanocortin (POMC) gene and rapid cellular proliferation, we examined whether intact POMC could b...

journal_title：Clinical endocrinology

authors： Raffin-Sanson ML,Massias JF,Ankotche A,Coste J,de Keyzer Y,Oliver C,Dumont C,Cabrol D,Ferré F,Bertagna X

更新日期：1999-01-01 00:00:00

abstract：CONTEXT:Few studies have evaluated the metabolic outcomes of growth hormone (GH) treatment in idiopathic short stature (ISS). Moreover, children with ISS appear to need higher GH doses than children with GH deficiency (GHD) to achieve the same amount of growth and may therefore be at increased risk of adverse events du...

journal_title：Clinical endocrinology

authors： Decker R,Albertsson-Wikland K,Kriström B,Nierop AF,Gustafsson J,Bosaeus I,Fors H,Hochberg Z,Dahlgren J

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Persistent elevation of urinary albumin excretion (UAE), even within normal range, is an independent predictor for cardiovascular disease. Accumulating research suggests that low levels of vitamin D and high levels of parathyroid hormone (PTH) also increase cardiovascular disease risk. This study is intended ...

journal_title：Clinical endocrinology

authors： Kim HW,Park H,Cho KH,Han K,Ko BJ

更新日期：2014-01-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP) is a highly basic 28 amino-acid peptide which was first isolated from porcine small intestine (Said & Mutt, 1970). It is related to several other peptides including PHI (peptide with N-terminal histidine and C-terminal isoleucine amide), secretin, glucagon, and has some sequences si...

journal_title：Clinical endocrinology

authors： Prysor-Jones RA,Jenkins JS

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVE:Primary hyperparathyroidism and calcium supplementation have been linked to cardiovascular outcomes. The study objective was to examine plasma calcium as a predictor of cardiovascular disease in the general population, as results from previous cohort studies are conflicting. DESIGN, PARTICIPANTS AND MEASUREM...

journal_title：Clinical endocrinology

authors： Walsh JP,Divitini ML,Knuiman MW

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:We postulated the mechanism for the association between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and insulin sensitivity might relate to changes in blood flow regulation. We studied the association of this polymorphism with insulin action, and insulin-mediated changes in...

journal_title：Clinical endocrinology

authors： Foo M,Coppack SW,Denver AE,Bulmer K,Yudkin JS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Acromegalic patients have increased left ventricular (LV) mass (M) and impaired diastolic function. AIM:Using ultrasonic cardiac tissue characterization, we evaluated the early changes in cardiac fibrosis (IBS) and intrinsic myocardial contractility (CVI) as well as their reversibility after treatment with ...

journal_title：Clinical endocrinology

authors： Bogazzi F,Di Bello V,Palagi C,Donne MG,Di Cori A,Gavioli S,Talini E,Cosci C,Sardella C,Brogioni S,Mariani M,Martino E

更新日期：2005-05-01 00:00:00

abstract：CONTEXT & OBJECTIVE:A recent paper by our group reported that regular aerobic exercise during pregnancy led to lower foetal IGF-I and IGF-II concentrations and a modest reduction in offspring birth weight when compared with the offspring of nontraining control participants. Maternal hormonal alterations in response to ...

journal_title：Clinical endocrinology

authors： Hopkins SA,Baldi JC,Cutfield WS,McCowan L,Hofman PL

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:Massive macronodular adrenocortical disease (MMAD) may be caused by aberrant microRNA expression. To determine the microRNA profile in MMAD and identify putative microRNA-gene target pairs involved in adrenal tumourigenesis. EXPERIMENTAL DESIGN:We performed microRNA microarray analysis in 10 patients with ACTH...

journal_title：Clinical endocrinology

authors： Bimpaki EI,Iliopoulos D,Moraitis A,Stratakis CA

更新日期：2010-06-01 00:00:00

abstract：:Thyroid status was estimated serially by measuring triiodothyronine (T3), thyroxine (T4) and thyrotrophin (hTSH) in 20 patients suffering from meningococcal meningitis, typhoid fever and other acute febrile illnesses. Significantly low T3 and only slightly increased T4 were observed in all the patients. hTSH was norma...

journal_title：Clinical endocrinology

authors： Maharajan G,Etta KM,Singh A,Ahuja IS,Ahuja GK

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Distinguishing malignant thyroid nodules in patients with follicular cytology by fine-needle aspiration (FNA) remains problematic. The large majority of thyroid nodules (> 85%) are overtreated. Therefore, a clear need exists to develop more accurate initial diagnostic tests for follicular thyroid nodules. Ga...

journal_title：Clinical endocrinology

authors： Hooft L,van der Veldt AA,Hoekstra OS,Boers M,Molthoff CF,van Diest PJ

更新日期：2008-02-01 00:00:00

abstract：:The concentration of immunoreactive inhibin in serum was measured in three pregnant women with premature ovarian failure involved in a donor oocyte in-vitro fertilization programme. Inhibin was not detectable in peripheral serum prior to conception but rose within 2-4 weeks of embryo transfer, whereafter levels rose g...

journal_title：Clinical endocrinology

authors： McLachlan RI,Healy DL,Lutjen PJ,Findlay JK,De Kretser M,Burger HG

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:Centripetal obesity is associated with systemic low-grade inflammation and an increased cardiovascular risk. Patients in long-term remission of Cushing's syndrome (CS) report persisting abdominal fat accumulation. However, this has previously not been adequately objectified. Therefore, we investigated the adi...

journal_title：Clinical endocrinology

authors： Wagenmakers M,Roerink S,Gil L,Plantinga T,Smit J,Netea-Maier R,Hermus A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Acromegalic patients have increased prevalence of colonic polyps. Development of hyperplastic polyps was related to suppressor of cytokine signalling (SOCS) 2 haploinsufficiency in animal models of acromegaly. OBJECTIVE AND PATIENTS:To evaluate whether variations in SOCS2 expression in the colonic mucosa of...

journal_title：Clinical endocrinology

authors： Bogazzi F,Ultimieri F,Raggi F,Russo D,Costa A,Marciano E,Bartalena L,Martino E

更新日期：2009-06-01 00:00:00

abstract：:A wide variety of adverse effects of methimazole (MMI) have been reported. Here we report a new MMI-induced disorder, acute pancreatitis and parotitis. Three weeks after a woman started MMI treatment for Graves' disease, she developed a high fever, painful parotid swelling and dull pain in the upper abdomen with eleva...

journal_title：Clinical endocrinology

authors： Taguchi M,Yokota M,Koyano H,Endo Y,Ozawa Y

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between circulating leptin levels, bone mineral content and density in the elderly. DESIGN:A cross-sectional study. PATIENTS:A cohort of 92 men and 171 women, with ages ranging from 68 to 75 years, selected as a healthy and normal functioning group, in the city centre of Verona. ...

journal_title：Clinical endocrinology

authors： Zoico E,Zamboni M,Adami S,Vettor R,Mazzali G,Tosoni P,Bissoli L,Bosello O

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Vascular dysfunction and accelerated atherosclerosis are prominent features of hypothyroidism. The relative roles of thyroid hormone (TH) deficiency and the associated vascular risk conditions are still unclear. We studied the impact of acute and chronic hypothyroidism on vascular reactivity. PATIENTS:We stu...

journal_title：Clinical endocrinology

authors： Napoli R,Guardasole V,Zarra E,D'Anna C,De Sena A,Lupoli GA,Oliviero U,Matarazzo M,Lupoli G,Saccà L

更新日期：2010-01-01 00:00:00

abstract：:Ten patients (seven women, three men) with active acromegaly, five previously treated and five newly diagnosed, were included in an open-label prospective trial of 3 daily subcutaneous injections of the long-acting somatostatin analogue SMS 201-995 (Sandostatin) at increasing doses in order to obtain maximum growth ho...

journal_title：Clinical endocrinology

authors： Shi YF,Harris AG,Zhu XF,Deng JY

更新日期：1990-06-01 00:00:00

abstract：:Infertility with azoospermia requires a diligent search for reversible factors and treatment to restore natural fertility, even though most cases are due to untreatable primary spermatogenic failure and are destined to require consideration of assisted reproductive treatment (ART) options. Complete clinical and diagno...

journal_title：Clinical endocrinology

authors： McLachlan RI

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:The success of a low-iodine diet (LID) is best determined by measurement of 24-h urine iodine (U-I) excretion. The aim of this study was to determine reliable estimates for 24-h U-I based on spot-urine samples and to provide cut-offs to determine the effectiveness of LID preparation. DESIGN:We prospectively ...

journal_title：Clinical endocrinology

authors： Kim HK,Lee SY,Lee JI,Jang HW,Kim SK,Chung HS,Tan AH,Hur KY,Kim JH,Chung JH,Kim SW

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Acylation-stimulating protein (ASP) is an adipose tissue-derived hormone, which stimulates glucose and free fatty acid (FFA) uptake into adipocytes. Changes in ASP metabolism are associated with alterations in lipid metabolism. As postnatal catch-up growth has been associated with dyslipidaemia in...

journal_title：Clinical endocrinology

authors： Leunissen RW,Gao Y,Cianflone K,Stijnen T,Hokken-Koelega AC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Assessment of the hypothalamic-pituitary-adrenal (HPA) axis after pituitary surgery is important for appropriate decision making regarding replacement therapy. The synacthen test is often used but is questioned, as time has to elapse for adrenal atrophy to develop. OBJECTIVE:To audit the use of the 250 micr...

journal_title：Clinical endocrinology

authors： Klose M,Lange M,Kosteljanetz M,Poulsgaard L,Feldt-Rasmussen U

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence and progression of subclinical hypothyroidism in women with type 2 diabetes. DESIGN AND PATIENTS:Cross-sectional and longitudinal observational assessment of thyroid function in 420 adult females with type 2 diabetes randomly selected from participants in the community-based Fremantl...

journal_title：Clinical endocrinology

authors： Chubb SA,Davis WA,Inman Z,Davis TM

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Abnormal serum liver function tests are common in patients with untreated thyrotoxicosis, even prior to the initiation of antithyroidal medications that may worsen the severity of the abnormal serum liver biochemistries. There is a wide range of the incidence of these abnormalities in the published literature...

journal_title：Clinical endocrinology

authors： Lin TY,Shekar AO,Li N,Yeh MW,Saab S,Wilson M,Leung AM

更新日期：2017-05-01 00:00:00