Abstract:
:Left ventricular (LV) failure is the main cause of death in thalassemia. Iron overload in patients with thalassemia leads to the formation of oxygen free radicals. Of the various apolipoprotein E (apoE) alleles, apoE4 is the least efficient in conditions of oxidative stress in comparison with apoE2 and apoE3. Our results showed that apoE4 is a genetic risk factor for LV dysfunction in thalassemia.
journal_name
Haematologicajournal_title
Haematologicaauthors
Bazrgar M,Karimi M,Peiravian F,Fathzadeh Mdoi
10.3324/haematol.10708subject
Has Abstractpub_date
2007-02-01 00:00:00pages
256-7issue
2eissn
0390-6078issn
1592-8721journal_volume
92pub_type
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