当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Effective connectivity in target stimulus processing: a dynamic causal modeling study of visual oddball task.

Effective connectivity in target stimulus processing: a dynamic causal modeling study of visual oddball task.

Abstract：

PURPOSE:To investigate the fundamental connectivity architecture of neural structures involved in the goal-directed processing of target events. METHODS:Twenty healthy volunteers underwent event-related functional magnetic resonance imaging (fMRI) while performing a standard oddball task. In the task, two types of visual stimuli - rare (target) and frequent - were randomly presented, and subjects were instructed to mentally count the target stimuli. Dynamic causal modeling (DCM), in combination with Bayes factors was used to compare competing neurophysiological models with different intrinsic connectivity structures and input regions within the network of brain regions underlying target stimulus processing. RESULTS:Conventional analysis of fMRI data revealed significantly greater activation in response to the target stimuli (in comparison to the frequent stimuli) in several brain regions, including the intraparietal sulci and supramarginal gyri, the anterior and posterior cingulate gyri, the inferior and middle frontal gyri, the superior temporal sulcus, the precuneus/cuneus, and the subcortical grey matter (caudate and thalamus). The most extensive cortical activations were found in the right intraparietal sulcus (IPS), the anterior cingulate cortex (ACC), and the right lateral prefrontal cortex (PFC). These three regions were entered into the DCM. A comparison on a group level revealed that the dynamic causal models in which the ACC and alternatively the IPS served as input regions were superior to a model in which the PFC was assumed to receive external inputs. No significant difference was observed between the fully connected models with ACC and IPS as input regions. Subsequent analysis of the intrinsic connectivity within two investigated models (IPS and ACC) disclosed significant parallel forward connections from the IPS to the frontal areas and from the ACC to the PFC and the IPS. CONCLUSION:Our findings indicate that during target stimulus processing there is a bidirectional frontoparietal information flow, very likely reflecting parallel activation of two distinct but partially overlapping attentional or attentional/event-encoding neural systems. Additionally, a simple hierarchy within the right frontal lobe is suggested with the ACC exerting influence over the PFC.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Brázdil M,Mikl M,Marecek R,Krupa P,Rektor I

doi

10.1016/j.neuroimage.2006.12.020

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

827-35

issue

2

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(06)01186-4

journal_volume

35

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • A NO way to BOLD? Dietary nitrate alters the hemodynamic response to visual stimulation.

    abstract：:Neurovascular coupling links neuronal activity to vasodilation. Nitric oxide (NO) is a potent vasodilator, and in neurovascular coupling NO production from NO synthases plays an important role. However, another pathway for NO production also exists, namely the nitrate-nitrite-NO pathway. On this basis, we hypothesized...

    journal_title：NeuroImage

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.neuroimage.2013.06.069

    authors： Aamand R,Dalsgaard T,Ho YC,Møller A,Roepstorff A,Lund TE

    更新日期：2013-12-01 00:00:00

  • The test-retest reliability of 18F-DOPA PET in assessing striatal and extrastriatal presynaptic dopaminergic function.

    abstract：:Brain presynaptic dopaminergic function can be assessed using 18F-DOPA positron emission tomography (PET). Regional 18F-DOPA utilization may be used to index dopaminergic abnormalities over time or dopaminergic response to treatment in clinical populations. Such studies require prior knowledge of the stability of the ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.12.058

    authors： Egerton A,Demjaha A,McGuire P,Mehta MA,Howes OD

    更新日期：2010-04-01 00:00:00

  • The spatial distribution of age-related white matter changes as a function of vascular risk factors--results from the LADIS study.

    abstract：:White matter hyperintensities (WMH) are a frequent finding on brain MRI of elderly subjects, and have been associated with various risk factors, as well as with development of cognitive and functional impairment. While an overall association between WMH load and risk factors is well described, possible spatially restr...

    journal_title：NeuroImage

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.neuroimage.2012.01.106

    authors： Rostrup E,Gouw AA,Vrenken H,van Straaten EC,Ropele S,Pantoni L,Inzitari D,Barkhof F,Waldemar G,LADIS study group.

    更新日期：2012-04-15 00:00:00

  • Thalamic cholinergic innervation makes a specific bottom-up contribution to signal detection: Evidence from Parkinson's disease patients with defined cholinergic losses.

    abstract：:Successful behavior depends on the ability to detect and respond to relevant cues, especially under challenging conditions. This essential component of attention has been hypothesized to be mediated by multiple neuromodulator systems, but the contributions of individual systems (e.g., cholinergic, dopaminergic) have r...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.02.006

    authors： Kim K,Müller MLTM,Bohnen NI,Sarter M,Lustig C

    更新日期：2017-04-01 00:00:00

  • Negative edges and soft thresholding in complex network analysis of resting state functional connectivity data.

    abstract：:Complex network analyses of functional connectivity have consistently revealed non-random (modular, small-world, scale-free-like) behavior of hard-thresholded networks constructed from the right-tail of the similarity histogram. In the present study we determined network properties resulting from edges constrained to ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.12.047

    authors： Schwarz AJ,McGonigle J

    更新日期：2011-04-01 00:00:00

  • Precise Inference and Characterization of Structural Organization (PICASO) of tissue from molecular diffusion.

    abstract：:Inferring the microstructure of complex media from the diffusive motion of molecules is a challenging problem in diffusion physics. In this paper, we introduce a novel representation of diffusion MRI (dMRI) signal from tissue with spatially-varying diffusivity using a diffusion disturbance function. This disturbance f...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.09.057

    authors： Ning L,Özarslan E,Westin CF,Rathi Y

    更新日期：2017-02-01 00:00:00

  • Space-time-frequency analysis of EEG data using within-subject statistical tests followed by sequential PCA.

    abstract：:A new method is developed for analyzing the time-varying spectral content of EEG data collected in cognitive tasks. The goal is to extract and summarize the most salient features of numerical results, which span space, time, frequency, task conditions, and multiple subjects. Direct generalization of an established app...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.09.020

    authors： Ferree TC,Brier MR,Hart J Jr,Kraut MA

    更新日期：2009-03-01 00:00:00

  • Optimizing power to track brain degeneration in Alzheimer's disease and mild cognitive impairment with tensor-based morphometry: an ADNI study of 515 subjects.

    abstract：:Tensor-based morphometry (TBM) is a powerful method to map the 3D profile of brain degeneration in Alzheimer's disease (AD) and mild cognitive impairment (MCI). We optimized a TBM-based image analysis method to determine what methodological factors, and which image-derived measures, maximize statistical power to track...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.07.011

    authors： Hua X,Lee S,Yanovsky I,Leow AD,Chou YY,Ho AJ,Gutman B,Toga AW,Jack CR Jr,Bernstein MA,Reiman EM,Harvey DJ,Kornak J,Schuff N,Alexander GE,Weiner MW,Thompson PM,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2009-12-01 00:00:00

  • Can magnetoencephalography track the afferent information flow along white matter thalamo-cortical fibers?

    abstract：:White matter thalamo-cortical fibers allow the communication of distant brain regions by carrying neuronal signals. Mapping non-invasively the information flow within white matter fibers is regarded so far as impossible. We investigated here whether information flow propagating along thalamo-cortical fibers can be det...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.01.054

    authors： Papadelis C,Leonardelli E,Staudt M,Braun C

    更新日期：2012-04-02 00:00:00

  • Increased DAT binding in the early stage of the dopaminergic lesion: a longitudinal [11C]PE2I binding study in the MPTP-monkey.

    abstract：:The delayed appearance of motor symptoms in PD poses a crucial challenge for early detection of the disease. We measured the binding potential of the selective dopamine active transporter (DAT) radiotracer [(11)C]PE2I in MPTP-treated macaque monkeys, thus establishing a detailed profile of the nigrostriatal DA status ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.07.059

    authors： Vezoli J,Dzahini K,Costes N,Wilson CR,Fifel K,Cooper HM,Kennedy H,Procyk E

    更新日期：2014-11-15 00:00:00

  • Separate neural systems for processing action- or non-action-related sounds.

    abstract：:The finding of a multisensory representation of actions in a premotor area of the monkey brain suggests that similar multimodal action-matching mechanisms may also be present in humans. Based on the existence of an audiovisual mirror system, we investigated whether sounds referring to actions that can be performed by ...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.neuroimage.2004.09.025

    authors： Pizzamiglio L,Aprile T,Spitoni G,Pitzalis S,Bates E,D'Amico S,Di Russo F

    更新日期：2005-02-01 00:00:00

  • Functional connectivity of the human insular cortex during noxious and innocuous thermal stimulation.

    abstract：:The insula plays a key role in brain processing of noxious and innocuous thermal stimuli. The anterior and the posterior portions of the insular cortex are involved in different ways in nociceptive and thermoceptive processing. Therefore, their stimulus-specific functional connectivity may also differ. Here we used fu...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.09.012

    authors： Peltz E,Seifert F,DeCol R,Dörfler A,Schwab S,Maihöfner C

    更新日期：2011-01-15 00:00:00

  • Dynamic neuroimaging of retinal light responses using fast intrinsic optical signals.

    abstract：:Transient intrinsic optical responses associated with neural activation offer an attractive strategy for dynamic imaging of neural activity, and may provide a noninvasive methodology for imaging of retinal function. Here we demonstrate the feasibility of near infrared imaging of fast intrinsic optical changes in isola...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.06.060

    authors： Yao XC,George JS

    更新日期：2006-11-15 00:00:00

  • Subthalamic nucleus activity dissociates proactive and reactive inhibition in patients with Parkinson's disease.

    abstract：:Models of action selection postulate the critical involvement of the subthalamic nucleus (STN), especially in reactive inhibition processes when inappropriate responses to a sudden stimulus must be overridden. The STN could also play a key role during proactive inhibition, when subjects prepare to potentially suppress...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.10.070

    authors： Benis D,David O,Lachaux JP,Seigneuret E,Krack P,Fraix V,Chabardès S,Bastin J

    更新日期：2014-05-01 00:00:00

  • SMAC: Spatial multi-category angle-based classifier for high-dimensional neuroimaging data.

    abstract：:With the development of advanced imaging techniques, scientists are interested in identifying imaging biomarkers that are related to different subtypes or transitional stages of various cancers, neuropsychiatric diseases, and neurodegenerative diseases, among many others. In this paper, we propose a novel spatial mult...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.03.040

    authors： Yu-Feng Liu L,Liu Y,Zhu H,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2018-07-15 00:00:00

  • Bottom up modeling of the connectome: linking structure and function in the resting brain and their changes in aging.

    abstract：:With the increasing availability of advanced imaging technologies, we are entering a new era of neuroscience. Detailed descriptions of the complex brain network enable us to map out a structural connectome, characterize it with graph theoretical methods, and compare it to the functional networks with increasing detail...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2013.04.055

    authors： Nakagawa TT,Jirsa VK,Spiegler A,McIntosh AR,Deco G

    更新日期：2013-10-15 00:00:00

  • Visual cortical networks align with behavioral measures of context-sensitivity in early childhood.

    abstract：:This study investigates how visual cortical networks align with context-sensitivity, namely the relative focus on the object versus the background of a visual scene, in early childhood. Context-sensitivity was assessed by a picture description and a recognition memory task. To segregate object and background processin...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.08.008

    authors： Köster M,Castel J,Gruber T,Kärtner J

    更新日期：2017-12-01 00:00:00

  • Characterizing Inscapes and resting-state in MEG: Effects in typical and atypical development.

    abstract：:Examining the brain at rest is a powerful approach used to understand the intrinsic properties of typical and disordered human brain function, yet task-free paradigms are associated with greater head motion, particularly in young and/or clinical populations such as autism spectrum disorder (ASD) and attention-deficit/...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.117524

    authors： Vandewouw MM,Dunkley BT,Lerch JP,Anagnostou E,Taylor MJ

    更新日期：2021-01-15 00:00:00

  • Reward expectation modulates feedback-related negativity and EEG spectra.

    abstract：:The ability to evaluate outcomes of previous decisions is critical to adaptive decision-making. The feedback-related negativity (FRN) is an event-related potential (ERP) modulation that distinguishes losses from wins, but little is known about the effects of outcome probability on these ERP responses. Further, little ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.11.056

    authors： Cohen MX,Elger CE,Ranganath C

    更新日期：2007-04-01 00:00:00

  • Face processing regions are sensitive to distinct aspects of temporal sequence in facial dynamics.

    abstract：:Facial movement conveys important information for social interactions, yet its neural processing is poorly understood. Computational models propose that shape- and temporal sequence sensitive mechanisms interact in processing dynamic faces. While face processing regions are known to respond to facial movement, their s...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.08.011

    authors： Reinl M,Bartels A

    更新日期：2014-11-15 00:00:00

  • Central artery stiffness, baroreflex sensitivity, and brain white matter neuronal fiber integrity in older adults.

    abstract：:Cerebral hypoperfusion elevates the risk of brain white matter (WM) lesions and cognitive impairment. Central artery stiffness impairs baroreflex, which controls systemic arterial perfusion, and may deteriorate neuronal fiber integrity of brain WM. The purpose of this study was to examine the associations among brain ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.01.041

    authors： Tarumi T,de Jong DL,Zhu DC,Tseng BY,Liu J,Hill C,Riley J,Womack KB,Kerwin DR,Lu H,Munro Cullum C,Zhang R

    更新日期：2015-04-15 00:00:00

  • Compensation of susceptibility-induced BOLD sensitivity losses in echo-planar fMRI imaging.

    abstract：:Gradient-echo echo-planar imaging is a standard technique in functional magnetic resonance imaging (fMRI) experiments based on the blood oxygenation level-dependent (BOLD) effect. A major problem is the occurrence of susceptibility gradients near air/tissue interfaces. As a consequence, the detection of neuronal activ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.2001.0985

    authors： Deichmann R,Josephs O,Hutton C,Corfield DR,Turner R

    更新日期：2002-01-01 00:00:00

  • LEAP: learning embeddings for atlas propagation.

    abstract：:We propose a novel framework for the automatic propagation of a set of manually labeled brain atlases to a diverse set of images of a population of subjects. A manifold is learned from a coordinate system embedding that allows the identification of neighborhoods which contain images that are similar based on a chosen ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.09.069

    authors： Wolz R,Aljabar P,Hajnal JV,Hammers A,Rueckert D,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2010-01-15 00:00:00

  • EEG correlates of time-varying BOLD functional connectivity.

    abstract：:Recent resting-state fMRI studies have shown that the apparent functional connectivity (FC) between brain regions may undergo changes on time-scales of seconds to minutes, the basis and importance of which are largely unknown. Here, we examine the electrophysiological correlates of within-scan FC variations during a c...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.01.049

    authors： Chang C,Liu Z,Chen MC,Liu X,Duyn JH

    更新日期：2013-05-15 00:00:00

  • The influence of the diffusion of responsibility effect on outcome evaluations: electrophysiological evidence from an ERP study.

    abstract：:Previous studies have revealed that personal responsibility has an influence on outcome evaluation, although the way this influence works is still unclear. This study imitated the phenomenon of responsibility diffusion in a laboratory to examine the influence of the effect of responsibility diffusion on the processing...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.04.275

    authors： Li P,Jia S,Feng T,Liu Q,Suo T,Li H

    更新日期：2010-10-01 00:00:00

  • Assessing white matter microstructure of the newborn with multi-shell diffusion MRI and biophysical compartment models.

    abstract：:Brain white matter connections have become a focus of major interest with important maturational processes occurring in newborns. To study the complex microstructural developmental changes in-vivo, it is imperative that non-invasive neuroimaging approaches are developed for this age-group. Multi-b-value diffusion weig...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.03.057

    authors： Kunz N,Zhang H,Vasung L,O'Brien KR,Assaf Y,Lazeyras F,Alexander DC,Hüppi PS

    更新日期：2014-08-01 00:00:00

  • Multiple foci of spatial attention in multimodal working memory.

    abstract：:The maintenance of sensory information in working memory (WM) is mediated by the attentional activation of stimulus representations that are stored in perceptual brain regions. Using event-related potentials (ERPs), we measured tactile and visual contralateral delay activity (tCDA/CDA components) in a bimodal WM task ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.08.019

    authors： Katus T,Eimer M

    更新日期：2016-11-15 00:00:00

  • Neuroplasticity to a single-episode traumatic stress revealed by resting-state fMRI in awake rats.

    abstract：:Substantial evidence has suggested that the brain structures of the medial prefrontal cortex (mPFC) and amygdala (AMYG) are implicated in the pathophysiology of stress-related disorders. However, little is known with respect to the system-level adaptation of their neural circuitries to the perturbations of traumatic s...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.08.050

    authors： Liang Z,King J,Zhang N

    更新日期：2014-12-01 00:00:00

  • Inter-individual variation in blood pressure is associated with regional white matter integrity in generally healthy older adults.

    abstract：:Prior studies have documented a range of brain changes that occur as a result of healthy aging as well as neural alterations due to profound dysregulation in vascular health such as extreme hypertension, cerebrovascular disease and stroke. In contrast, little information exists about the more transitionary state betwe...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.07.033

    authors： Salat DH,Williams VJ,Leritz EC,Schnyer DM,Rudolph JL,Lipsitz LA,McGlinchey RE,Milberg WP

    更新日期：2012-01-02 00:00:00

  • Cortical reactivations during sleep spindles following declarative learning.

    abstract：:Increasing evidence suggests that sleep spindles are involved in memory consolidation, but few studies have investigated the effects of learning on brain responses associated with spindles in humans. Here we used simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) during sleep to...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.03.051

    authors： Jegou A,Schabus M,Gosseries O,Dahmen B,Albouy G,Desseilles M,Sterpenich V,Phillips C,Maquet P,Grova C,Dang-Vu TT

    更新日期：2019-07-15 00:00:00