Abstract：
:Ewing's tumor of bone is the second primary malignant bone tumor. Localized lesion is found in nearly 80% of cases and metastatic lesions are present in 20% at the time of diagnosis. Treatment protocols were analyzed, prognostic parameters were evaluated, and overall survival as well as survival until relapse of disease was studied. Prognostic features included age and sex, localization of tumor, type of applied surgical resection and treatment protocol, and presence of necrosis after neoadjuvant therapy as well as morphological characteristics of the tumor. Wide surgical resection (chi2 = 7.855; p < 0.05), and tumor necrosis (chi2 = 7.855; p < 0.05) were verified to be significant parameters for the outcome. Multimodal chemotherapy with local radiation and/or surgical resection is the best mode of modern treatment. Follow-up included the period from the completion of therapy to final control, with remission period defined by development of recurrence or metastatic lesions. Localization on distal parts of the extremities and axial skeleton is good prognostic feature, while localization on proximal parts of the extremities and pelvic girdle, presence of metastatic disease and low index of postchemotherapeutic necrosis, are associated with poor outcome. In Ewing's sarcoma, prognosis of good outcome is definitely very delicate process.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Stevanović V,Vukasinović Z,Spasovski Ddoi
10.2298/sarh0610420ssubject
Has Abstractpub_date
2006-09-01 00:00:00pages
420-6issue
9-10eissn
0370-8179issn
2406-0895journal_volume
134pub_type
杂志文章abstract：INTRODUCTION:Cardiovascular autonomic modulation is altered in patients with essential hypertension. OBJECTIVE:To evaluate acute and long-term effects of amlodipine on cardiovascular autonomic function and haemodynamic status in patients with mild essential hypertension. METHODS:Ninety patients (43 male, mean age 52....
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0908371m
更新日期：2009-07-01 00:00:00
abstract：:Ataxia is defined as a disturbance which, quite independent of any motor weakness, alters direction and extent of voluntary movement and impairs the sustained voluntary of reflex muscle contraction necessary for maintaining postiue and equilibrium [1]. Since pathophysiological basis of cerebeller ataxia is still not c...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：INTRODUCTION:Obstructive sleep apnoea (OSA) syndrome represents a significant medical problem due to numerous consequences that may follow it. OBJECTIVE:The aim of the study was to analyze morphology of the maxilla in children with mouth breathing, and to assess possible characteristics in persons with marked clinical...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1204159v
更新日期：2012-03-01 00:00:00
abstract：:The recent data about the treatment of advanced breast cancer patients with synthetic LH-RH analogues are presented. Although synthetized 20 years ago, the agonistic analogues of LH-RH were introduced in clinical oncology recently. The inhibition of pituitary and gonadal function that occurs after chronic administrati...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:In diabetic patients, without coronary heart disease and hypertension, left ventricular filing dysfunction exist, that is registered by echocardiography. It is manifested as greater peak flow velocity during atrial systole and as shorter time from the aortic second heart sound to the peak of the early diastolic flow v...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：:The urinary tract infection is very frequent, especially if calculosis of the urinary tract is present. Urinary infection is widespread, and it appears during the year. The people of all ages and both sexes are affected by urinary infection. In the last few years a reliable progress in the understanding and management...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
abstract：INTRODUCTION:The paper presents important facts in the application of recombinant human factor VIIa (rFVIIa) and in the treatment of renal cell carcer. CASE REPORT:A 69-year old male with infiltrative renal cell carcer underwent radical nephrectomy using Hasagawa's approach. The extirpated tumor was 35 cm in diameter....
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh08s3259j
更新日期：2008-09-01 00:00:00
abstract：INTRODUCTION:QT dispersion (QTd) is a measure of non-homogeneous repolarisation of the myocardium and is used as an indicator of arrhythmogenicity. OBJECTIVE:The aim of this study was to assess the relation between QT dispersion, left ventricle systolic function and frequency of ventricular arrhythmias in coronary pat...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0708395s
更新日期：2007-07-01 00:00:00
abstract：:This review is a brief overview of recent advances in biology as well as in potential clinical application of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF). Biologically active rhGM-CSF is a recombinant human protein expressed in Escherichia coli. GM-CSF is produced by nontransformed (T...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1993-08-01 00:00:00
abstract：:Intradermal injection with alpha-lactoalbumine, 2000 PNU/ml was carried out in seven patients (1 male, 6 females, mean age 32.4 years) suffering from milk intolerance. None of the patients had a positive allergen-specific IgE antibodies in the sera (RAST). Skin test was performed on the volar part of the forearms at t...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
abstract：INTRODUCTION:Hepatitis E is one of the leading clinical manifestations of acute viral hepatitis in developing countries. In industrialized countries, during the past several years, sporadic "autochthonous" cases of HEV infection have been increased. OBJECTIVE:The aim of this study was to analyze the epidemiological, c...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1602063b
更新日期：2016-01-01 00:00:00
abstract：:The existing data bases - on the number and distribution of the injured are unfortunately unreliable and very poor. There is also a shortage of information needed in assessing human and financial aspect of the trauma as well as physical, social, economic and psychological circumstances under wich injuries have heppene...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：INTRODUCTION:Because apical periodontitis is recognizably an infectious disease, elimination or reduction of intracanal bacteria is of utmost importance for optimum treatment outcome. OBJECTIVE:The prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals was studied Also, the effect of ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1410535s
更新日期：2014-09-01 00:00:00
abstract：INTRODUCTION:At the Department of Minimally Invasive Upper Digestive Surgery of the Hospital for Digestive Surgery in Belgrade, hybrid minimally invasive esophagectomy (hMIE) has been a standard of care for patients with resectable esophageal cancer since 2009. As a next and final step in the change management, from Ja...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1508410b
更新日期：2015-07-01 00:00:00
abstract：:The paper is aimed at illustrating the importance of nonspecific and specific bronchoprovokative tests for diagnosing allergic bronchial asthma by pathophysiologic mechanisms of hyperiritability of airways and making of specific "schok tissue". Besides we tried to explain these exeptional cases which we encounter in o...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Maria Müller was one of the first female ophthalmologists in Serbia. Having researched the documents from several archives in Serbia-Belgrade, Novi Sad and Sremska Mitrovica, we were able to follow her life and work. Maria Müller was born in Budapest in 1883. From 1909 to 1919 she worked at the Budapest Hungarian Roya...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:Hand dominance is defined as a proneness to use one hand rather than another in performing the majority of activities and this is the most obvious example of cerebral lateralization and an exclusive human characteristic. Left-handed people comprise 6-14% of the total population, while in Serbia, this percentage is 5-1...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：10.2298/sarh1006387m
更新日期：2010-05-01 00:00:00
abstract：INTRODUCTION:Enamel surface around restoration is very sensitive to the effect of cariogenic solution. It is the consequence of the manner the cavity is prepared before restoration, the existence of marginal cracks around restoration, that is, irregular polishing of filling. OBJECTIVE:The aim of this study is to analy...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0808361d
更新日期：2008-07-01 00:00:00
abstract：:Chlamydia trachomatis is an ubiquitous bacterium, strictly intracellular organism. The D-K serovars urethritis, cervicitis, endometritis, salpingitis, periappendicitis and perihepatitis, in women, urethritis, prostatitis, epididymitis and Reiter's syndrome in 1-2% of cases in men. Sterility is the most serious complic...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Inflammatory response in tissue results from a complex network of interactions between inflammatory cells (mast cells, eosinophils, basophils, macrophages) and resident cells belonging to the lung structure (like endothelial cells, fibroblasts, epithelial cells). Among structural cells, endothelial cells play a critic...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1998-03-01 00:00:00
abstract：:The purpose of this study was to analyse, by immunomorphometry, megakaryocytopoiesis in patients with myelodysplatsic syndrome. The results revealed that, in spite of marked megakaryocyte hyperplasia, patients with myelodysplastic syndrome suffer from severe peripheral thrombocytopenia. Megakaryocytes in myelodisplast...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1992-11-01 00:00:00
abstract：INTRODUCTION:Correct choice of osteosynthesis method is a very important factor in providing the optimal conditions for appropriate healing of the fracture. There are still disagreements about the method of stabilization of some long bone fractures. Critically observed, no method of fracture fixation is ideal. Each ost...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1402040g
更新日期：2014-01-01 00:00:00
abstract：:Wilms' tumour, one of the most common solid tumours in children, is classified in groups with favourable, unfavourable and standard risk histology. Anaplastic Wilms' tumour is a representative of the tumours with unfavourable histology. Anaplasia (focal or diffuse) can involve ony component of the tumour but it has no...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：INTRODUCTION:Gluten-free diet (GFD) presents the basis of coeliac disease (CD) treatment. If strictly applied, the disorders of the small bowel mucosa and other disease signs rapidly resolve. OBJECTIVE:The goal of the study was to evaluate the effect of GFD on the growth and nutritional status of children with the cla...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0912632r
更新日期：2009-11-01 00:00:00
abstract：INTRODUCTION:Associated bone tissue defect and infection, commonly result in non-healing, i.e., by the development of infected tibial nonunion. OBJECTIVE:The aim of the paper was to present experiences acquired in the treatment of this problem by the application of the Ilizarov method. METHODS:The analyses enrolled 1...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,多中心研究
doi：10.2298/sarh1202065v
更新日期：2012-01-01 00:00:00
abstract：:Search and disclosure of most adequate diagnostic criteria and prognostic indicators of disease represents one of the most difficult tasks in the understanding of any disease, which creates the way toward a more successful treatment and longer survival. The recent advances in research techniques that have helped refin...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh11s2095d
更新日期：2011-12-01 00:00:00
abstract：INTRODUCTION:Moderate ischemic mitral regurgitation (MR) is characterized by significant, symptomatic multivessel coronary disease and mitral regurgitation 2-3+. CASE OUTLINE:A 60-year-old patient was admitted at the Cardiovascular Institute "Dedinje" due to the symptoms of unstable angina pectoris. He survived a myoc...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0906275t
更新日期：2009-05-01 00:00:00
abstract：:The occurrence of abnormal Hodgkin's and Reed-Sternberg cells in the peripheral blood in a patient suffering from Hodgkin's disease has been noticed exceptionally rare in a previous period, and especially rare in last ten years primarily due to successful treatment of this disease. The presence of atypical mononuclear...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0310400m
更新日期：2003-09-01 00:00:00
abstract：INTRODUCTION:Autoimmune cholangitis or immunoglobulin G4-associated cholangitis (IAC) has been recently regarded as a new clinical and histopathological entity and is a part of a complex autoimmune disorder--IgG4-related systemic disease (ISD). ISD is an autoimmune disease with multi-organic involvement, characterized ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1506337i
更新日期：2015-05-01 00:00:00
abstract：:Subclinical thyroid disease is defined by an abnormally high (subclinical hypothyroidism) or low (subclinical hyperthyroidism) serum thyrotropin (TSH) with peripheral thyroid hormone concentrations within the laboratory reference ranges. Such abnormalities in thyroid function tests are very common in the population an...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：2003-11-01 00:00:00
