Abstract:
:With advances in endoscopic imaging tools, it is becoming increasingly possible to find, assess and treat numerous gastrointestinal (GI) pathologies at the time of endoscopy. This article focuses on the newly developed Pentax confocal endomicroscope that enables in vivo microscopic imaging of the upper and lower GI tract in histological detail at the time of patient examination without the collection of biopsies. The optical imaging technique has the potential to revolutionize clinical workflows in endoscopy through high-resolution fluorescence imaging of cellular and subcellular detail from the surface and subepithelial layers of the GI mucosa. The device incorporates a full screen, high-resolution charge coupled device as well as a confocal microscope. Preliminary data from blinded clinical studies suggests that the use of this device can increase the diagnostic yield for disease detection in conditions such as ulcerative colitis and Barrett's esophagus, where diagnosis using white light endoscopy is problematic. The early detection and diagnosis of GI abnormalities through the collection of 'optical' biopsies or targeted mucosal excisional biopsies has the potential to improve patient outcomes and enable early therapeutic intervention.
journal_name
Expert Rev Med Devicesjournal_title
Expert review of medical devicesauthors
Polglase AL,McLaren WJ,Delaney PMdoi
10.1586/17434440.3.5.549subject
Has Abstractpub_date
2006-09-01 00:00:00pages
549-56issue
5eissn
1743-4440issn
1745-2422journal_volume
3pub_type
杂志文章abstract:INTRODUCTION:Despite the potential impact of missed visits on the outcomes of neuromodulation treatments, it is not clear how this issue has been addressed in clinical trials. Given this gap in the literature, we reviewed articles on non-invasive brain stimulation in participants with depression or chronic pain, and in...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2017.1352470
更新日期:2017-08-01 00:00:00
abstract:INTRODUCTION:Monitoring a patient's vital signs forms a basic component of care, enabling the identification of deteriorating patients and increasing the likelihood of improving patient outcomes. Several paper-based track and trigger warning scores have been developed to allow clinical evaluation of a patient and guida...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2019.1563480
更新日期:2019-02-01 00:00:00
abstract::The RNS(®) System is the first commercially available device to provide closed-loop responsive brain stimulation. The system includes a cranially implanted neurostimulator that continually monitors the electrocorticogram through one or two depth and/or subdural cortical strip leads that are placed at the seizure focus...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.2014.947274
更新日期:2014-11-01 00:00:00
abstract:INTRODUCTION:Percutaneous transcatheter balloon angioplasty has evolved to the current mainstay treatment for salvage of dysfunctional dialysis access. Nonetheless, it is frequently associated with recurrent vessel restenosis and the need for multiple repeat treatments in order to maintain hemodynamic patency. Cutting-...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2016.1254548
更新日期:2016-12-01 00:00:00
abstract::The advent of catheter ablation has revolutionized the treatment of supraventricular cardiac arrhythmias, including in the last few years, atrial fibrillation. The discovery of electrically active sleeves of atrial myocardium extending into the pulmonary veins has led to the development of pulmonary vein ostial ablati...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/erd.10.59
更新日期:2011-01-01 00:00:00
abstract::Introduction: It is common belief that driving with an implantable cardioverter defibrillator (ICD)/pacemaker (PM) might be associated with sudden cardiac incapacitation, road traffic accidents, and chance to harm to self and others. On the other hand, the ability to drive is highly valuable in the modern era, represe...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2020.1742108
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Anastomotic leak (AL) after colorectal surgery is a devastating complication; decreased blood perfusion is an important risk factor. Surgeons rely on subjective measures to assess bowel perfusion. Fluorescence imaging (FI) with indocyanine green (ICG) provides a real-time objective assessment of intestinal...
journal_title:Expert review of medical devices
pub_type: 杂志文章,meta分析,评审
doi:10.1080/17434440.2017.1265444
更新日期:2017-01-01 00:00:00
abstract::Devices for support of patients with liver failure are of two types: bioartificial livers and artificial livers. Bioartificial livers include hepatocytes in bioreactors to provide both excretory and synthetic liver functions. Artificial livers use nonliving components to remove toxins of liver failure, supply nutrient...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.4.6.839
更新日期:2007-11-01 00:00:00
abstract::Atrial fibrillation is a pervasive and difficult heart rhythm problem for more than 3 million Americans. Patients are plagued by myriad symptoms and are exposed to the risk of stroke. Attempts to restore normal rhythm with drug therapy have been largely unsuccessful and the complications associated with long-term anti...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/erd.09.9
更新日期:2009-05-01 00:00:00
abstract::Patellofemoral arthroplasty has been utilized as a treatment for isolated patellofemoral arthritis for more than 30 years. However, the use of this procedure remains controversial, as many surgeons prefer to use total knee arthroplasty, even for isolated patellofemoral arthritis. While historically, the results with t...
journal_title:Expert review of medical devices
pub_type: 杂志文章
doi:10.1586/erd.09.53
更新日期:2010-01-01 00:00:00
abstract::Conventional ultrasonography represents the first diagnostic imaging modality for the study of pancreatic tumors. Contrast-enhanced ultrasound has significantly improved the accuracy of first-line examination and may influence the choice of second-line investigations: multidetector computed tomography is considered th...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/erd.09.67
更新日期:2010-03-01 00:00:00
abstract:INTRODUCTION:Approximately one-third of all ischemic strokes and the ensuing health and economic burden can be attributed to the presence of atrial fibrillation (AF). The global prevalence of AF continues to rise, thus making it by far the most common diagnosed cardiac arrhythmia. Percutaneous left atrial appendage (LA...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2020.1837621
更新日期:2020-11-01 00:00:00
abstract::Introduction: Sleep assessment devices are essential for the detection, diagnosis, and monitoring of sleep disorders. This paper provides a state-of-the-art review and comparison of sleep assessment devices and a market analysis.Areas covered: Hardware devices are classified into contact and contactless devices. For e...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2019.1693890
更新日期:2019-12-01 00:00:00
abstract::This article investigates various neural machine interfaces for voluntary control of externally powered upper-limb prostheses. Epidemiology of upper limb amputation, as well as prescription and follow-up studies of externally powered upper-limb prostheses are discussed. The use of electromyographic interfaces and peri...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.4.1.43
更新日期:2007-01-01 00:00:00
abstract::In the last decade, bicomponent fibers have been proposed to fabricate bio-inspired systems for tissue repair, regenerative medicine, medical healthcare and clinical applications. In comparison with monocomponent fibers, key advantage concerns their ability of self-adapting to the physiological conditions through an e...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.2016.1126505
更新日期:2016-01-01 00:00:00
abstract::Inferior vena cava filters are widely accepted for pulmonary embolic prophylaxis in high-risk patients with contraindications to anticoagulation. While long-term complications have been associated with permanent filters, retrievable filters are now available and have resulted in the rapid expansion of this technology....
journal_title:Expert review of medical devices
pub_type: 杂志文章
doi:10.1586/erd.09.25
更新日期:2009-09-01 00:00:00
abstract::Ureteral stents are used in a variety of urological diseases and procedures. The majority of patients with indwelling ureteral stents experience bothersome symptoms and are at increased risk for urinary tract infection. Stent encrustation and the associated complications can also result in significant patient morbidit...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.3.3.395
更新日期:2006-05-01 00:00:00
abstract::Minimally invasive, catheter-based treatment of valvular dysfunction has become an integral part of clinical routine. As left heart valvular disease is much more common and thus commercially of interest, transcatheter solutions for the treatment of aortic and mitral valvular defects were the first to become broadly cl...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.2015.985654
更新日期:2015-03-01 00:00:00
abstract::The introduction of retrievable inferior vena cava (IVC) filters was an important step in the evolution of deep vein thrombosis/pulmonary embolism management. Their removability makes them preferred to permanent filters in many cases. IVC filter retrieval often occurs at a suboptimal rate, leading to complications ass...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/erd.12.65
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Improved survival following single ventricle palliation has led to a large population of patients with a univentricular circulation, many of whom develop heart failure. Increasing experience with ventricular assist devices (VAD) in children has paved the way for VAD support in those with failing univentric...
journal_title:Expert review of medical devices
pub_type: 杂志文章
doi:10.1080/17434440.2017.1332523
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION:Historically, patients with rotator cuff arthropathy had limited reconstructive options. The early generations of reverse total shoulder arthroplasty (rTSA) designs had increased failure rates due to loosening of glenoid baseplates secondary to excessive torques. In 1985, Paul Grammont introduced a prosthe...
journal_title:Expert review of medical devices
pub_type: 历史文章,杂志文章,评审
doi:10.1080/17434440.2019.1568237
更新日期:2019-02-01 00:00:00
abstract:INTRODUCTION:Transcatheter devices have contributed significantly to the advances achieved in treating many cardiovascular conditions over the last few decades. Sophisticated and detailed preclinical testing is not only a regulatory requirement to support an investigational device exemption (IDE) application, but more ...
journal_title:Expert review of medical devices
pub_type: 杂志文章
doi:10.1080/17434440.2017.1282313
更新日期:2017-02-01 00:00:00
abstract::Powered instruments have been introduced into otorhinolaryngology practice over the last decade. These instruments were accepted immediately by many institutions, and continuing development has led to the current use of microdebriders in a variety of surgical procedures in otorhinolaryngology. In clinical rhinology, t...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/erd.10.7
更新日期:2010-05-01 00:00:00
abstract::In this review, surface modification of implant devices by immobilization of biological molecules is discussed. A brief introduction to the development of biomolecular surface science is presented, followed by a review of current activities in selected fields. Bone-contacting devices and some cardiovascular implant de...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.4.3.361
更新日期:2007-05-01 00:00:00
abstract:INTRODUCTION:Coronary artery disease affecting myocardial perfusion continues to be the leading cause of cardiovascular morbidity and mortality worldwide. While invasive evaluation based on coronary angiography and flow measurements still is considered the reference technique for assessing myocardial perfusion, technol...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2020.1834844
更新日期:2020-11-01 00:00:00
abstract:INTRODUCTION:The surgical template is a guide aimed at directing the implant placement, tumor resection, osteotomy and bone repositioning. Using it, preoperative planning can be transferred to the actual surgical site, and the precision, safety and reliability of the surgery can be improved. However, the actual workflo...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2016.1218758
更新日期:2016-09-01 00:00:00
abstract::Surgeons often encounter the challenge of treating acquired abdominal wall defects following abdominal surgery. The current standard of practice is to repair most defects using permanent synthetic mesh material. Mesh augments the strength of the weakened abdominal wall fascia and enables the hernia repair to be perfor...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.3.5.657
更新日期:2006-09-01 00:00:00
abstract::To predict the spread of coronavirus disease globally and consequently prepare the hospital facilities with the required technology is a challenge. The availability of essential medical equipment to support patients affected by Covid-19 is globally limited. Areas covered This perspective gives a technical view of the ...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1080/17434440.2020.1772757
更新日期:2020-06-01 00:00:00
abstract::The subthalamic nucleus (STN) is the primary target for the chronic deep brain stimulation treatment of Parkinson's disease. STN neurons exhibit a variety of characteristic properties that may play a key role in the overall population response to deep brain stimulation. Neuroinformatics techniques, in particular compu...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.4.5.663
更新日期:2007-09-01 00:00:00
abstract::Consumer sleep tracking devices such as fitness trackers and smartphone apps have become increasingly popular. These devices claim to measure the sleep duration of their users and in some cases purport to measure sleep quality and awaken users from light sleep, potentially improving overall sleep. Most of these device...
journal_title:Expert review of medical devices
pub_type: 杂志文章,评审
doi:10.1586/17434440.2016.1171708
更新日期:2016-05-01 00:00:00