当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Influence of the stress hormone cortisol on fear conditioning in humans: evidence for sex differences in the response of the prefrontal cortex.

Influence of the stress hormone cortisol on fear conditioning in humans: evidence for sex differences in the response of the prefrontal cortex.

Abstract：

:The stress hormone cortisol is known to influence declarative memory and associative learning. In animals, stress has often been reported to have opposing effects on memory and learning in males and females. In humans, the effects of cortisol have mainly been studied at the behavioral level. The aim of the present experiment was to characterize the effects of a single cortisol dose (30 mg) on the hemodynamic correlates of fear conditioning. In a double-blind group comparison study subjects (17 females and 17 males) received 30 mg cortisol or placebo orally before participating in a discriminative fear conditioning paradigm. Results revealed that cortisol impaired electrodermal signs of learning (the first interval response) in males, while no conditioned SCRs emerged for the females independent of treatment. fMRI results showed that cortisol reduced activity for the CS+ > CS- comparison in the anterior cingulate, the lateral orbitofrontal cortex and the medial prefrontal cortex in males. Opposite findings (increase in these regions under cortisol) were detected in females. In addition, cortisol reduced the habituation in the CS+ > CS- contrast in the dorsolateral prefrontal cortex independent of sex. Finally, cortisol also modified the response to the electric shock (the UCS) by enhancing the activity of the anterior as well as the posterior cingulate. In sum, these findings demonstrate that in humans cortisol mostly influences prefrontal brain activation during fear conditioning and that these effects appear to be modulated by sex.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Stark R,Wolf OT,Tabbert K,Kagerer S,Zimmermann M,Kirsch P,Schienle A,Vaitl D

doi

10.1016/j.neuroimage.2006.05.046

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

1290-8

issue

3

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(06)00656-2

journal_volume

32

pub_type

杂志文章,随机对照试验

相关文献

NEUROIMAGE文献大全
  • Encoding and decoding in fMRI.

    abstract：:Over the past decade fMRI researchers have developed increasingly sensitive techniques for analyzing the information represented in BOLD activity. The most popular of these techniques is linear classification, a simple technique for decoding information about experimental stimuli or tasks from patterns of activity acr...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2010.07.073

    authors： Naselaris T,Kay KN,Nishimoto S,Gallant JL

    更新日期：2011-05-15 00:00:00

  • Voxel-based morphometry and automated lobar volumetry: the trade-off between spatial scale and statistical correction.

    abstract：:Voxel-based morphometry (VBM) and automated lobar region of interest (ROI) volumetry are comprehensive and fast methods to detect differences in overall brain anatomy on magnetic resonance images. However, VBM and automated lobar ROI volumetry have detected dissimilar gray matter differences within identical image set...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.07.018

    authors： Voormolen EH,Wei C,Chow EW,Bassett AS,Mikulis DJ,Crawley AP

    更新日期：2010-01-01 00:00:00

  • Effect of age and the APOE gene on metabolite concentrations in the posterior cingulate cortex.

    abstract：:Proton magnetic resonance spectroscopy (1H-MRS) has provided valuable information about the neurochemical profile of Alzheimer's disease (AD). However, its clinical utility has been limited in part by the lack of consistent information on how metabolite concentrations vary in the normal aging brain and in carriers of ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.03.031

    authors： Suri S,Emir U,Stagg CJ,Near J,Mekle R,Schubert F,Zsoldos E,Mahmood A,Singh-Manoux A,Kivimäki M,Ebmeier KP,Mackay CE,Filippini N

    更新日期：2017-05-15 00:00:00

  • Near-tubular fiber bundle segmentation for diffusion weighted imaging: segmentation through frame reorientation.

    abstract：:This paper proposes a methodology to segment near-tubular fiber bundles from diffusion weighted magnetic resonance images (DW-MRI). Segmentation is simplified by locally reorienting diffusion information based on large-scale fiber bundle geometry. Segmentation is achieved through simple global statistical modeling of ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.11.001

    authors： Niethammer M,Zach C,Melonakos J,Tannenbaum A

    更新日期：2009-03-01 00:00:00

  • Recommendations for motion correction of infant fNIRS data applicable to multiple data sets and acquisition systems.

    abstract：:Despite motion artifacts are a major source of noise in fNIRS infant data, how to approach motion correction in this population has only recently started to be investigated. Homer2 offers a wide range of motion correction methods and previous work on simulated and adult data suggested the use of Spline interpolation a...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.06.056

    authors： Di Lorenzo R,Pirazzoli L,Blasi A,Bulgarelli C,Hakuno Y,Minagawa Y,Brigadoi S

    更新日期：2019-10-15 00:00:00

  • Hybrid diffusion imaging.

    abstract：:Diffusion measurements in the human central nervous system are complex to characterize and a broad spectrum of methods have been proposed. In this study, a comprehensive diffusion encoding and analysis approach, hybrid diffusion imaging (HYDI), is described. The HYDI encoding scheme is composed of multiple concentric ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.02.050

    authors： Wu YC,Alexander AL

    更新日期：2007-07-01 00:00:00

  • On clustering fMRI time series.

    abstract：:Analysis of fMRI time series is often performed by extracting one or more parameters for the individual voxels. Methods based, e.g., on various statistical tests are then used to yield parameters corresponding to probability of activation or activation strength. However, these methods do not indicate whether sets of v...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.1998.0391

    authors： Goutte C,Toft P,Rostrup E,Nielsen F,Hansen LK

    更新日期：1999-03-01 00:00:00

  • Neural correlates of experimentally induced flow experiences.

    abstract：:Flow refers to a positive, activity-associated, subjective experience under conditions of a perceived fit between skills and task demands. Using functional magnetic resonance perfusion imaging, we investigated the neural correlates of flow in a sample of 27 human subjects. Experimentally, in the flow condition partici...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.08.019

    authors： Ulrich M,Keller J,Hoenig K,Waller C,Grön G

    更新日期：2014-02-01 00:00:00

  • A modified damped Richardson-Lucy algorithm to reduce isotropic background effects in spherical deconvolution.

    abstract：:Spherical deconvolution methods have been applied to diffusion MRI to improve diffusion tensor tractography results in brain regions with multiple fibre crossing. Recent developments, such as the introduction of non-negative constraints on the solution, allow a more accurate estimation of fibre orientations by reducin...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.09.033

    authors： Dell'acqua F,Scifo P,Rizzo G,Catani M,Simmons A,Scotti G,Fazio F

    更新日期：2010-01-15 00:00:00

  • Evidence for age-related changes in sensorimotor neuromagnetic responses during cued button pressing in a large open-access dataset.

    abstract：:Mu, beta, and gamma rhythms increase and decrease in amplitude during movement. This event-related synchronization (ERS) and desynchronization (ERD) can be readily recorded non-invasively using magneto- and electro-encephalography (M/EEG). In addition, event-related potentials and fields (i.e., evoked responses) can b...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.02.065

    authors： Bardouille T,Bailey L,CamCAN Group.

    更新日期：2019-06-01 00:00:00

  • Physiologically evoked neuronal current MRI in a bloodless turtle brain: detectable or not?

    abstract：:Contradictory reports regarding the detection of neuronal currents have left the feasibility of neuronal current MRI (ncMRI) an open question. Most previous ncMRI studies in human subjects are suspect due to their inability to separate or eliminate hemodynamic effects. In this study, we used a bloodless turtle brain p...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.06.017

    authors： Luo Q,Lu H,Lu H,Senseman D,Worsley K,Yang Y,Gao JH

    更新日期：2009-10-01 00:00:00

  • Sub-millimeter ECoG pitch in human enables higher fidelity cognitive neural state estimation.

    abstract：:Electrocorticography (ECoG), electrophysiological recording from the pial surface of the brain, is a critical measurement technique for clinical neurophysiology, basic neurophysiology studies, and demonstrates great promise for the development of neural prosthetic devices for assistive applications and the treatment o...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.04.027

    authors： Hermiz J,Rogers N,Kaestner E,Ganji M,Cleary DR,Carter BS,Barba D,Dayeh SA,Halgren E,Gilja V

    更新日期：2018-08-01 00:00:00

  • Multi-resolutional shape features via non-Euclidean wavelets: applications to statistical analysis of cortical thickness.

    abstract：:Statistical analysis on arbitrary surface meshes such as the cortical surface is an important approach to understanding brain diseases such as Alzheimer's disease (AD). Surface analysis may be able to identify specific cortical patterns that relate to certain disease characteristics or exhibit differences between grou...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.02.028

    authors： Kim WH,Singh V,Chung MK,Hinrichs C,Pachauri D,Okonkwo OC,Johnson SC,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2014-06-01 00:00:00

  • Voxel-based morphometry to detect brain atrophy in progressive mild cognitive impairment.

    abstract：:Recent research has shown an increased rate of conversion to dementia in subjects with mild cognitive impairment (MCI) compared to controls. However, there are no specific methods to predict who will later develop dementia. In the present study, 22 controls and 56 MCI subjects were followed on average for 37 months (m...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.06.016

    authors： Hämäläinen A,Tervo S,Grau-Olivares M,Niskanen E,Pennanen C,Huuskonen J,Kivipelto M,Hänninen T,Tapiola M,Vanhanen M,Hallikainen M,Helkala EL,Nissinen A,Vanninen R,Soininen H

    更新日期：2007-10-01 00:00:00

  • Predicting intrinsic brain activity.

    abstract：:Multivariate supervised learning methods exhibit a remarkable ability to decode externally driven sensory, behavioral, and cognitive states from functional neuroimaging data. Although they are typically applied to task-based analyses, supervised learning methods are equally applicable to intrinsic effective and functi...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.05.072

    authors： Craddock RC,Milham MP,LaConte SM

    更新日期：2013-11-15 00:00:00

  • Neural mechanisms involved in mental imagery and observation of gait.

    abstract：:Brain activity during observation and imagery of gait was investigated. Sixteen subjects were scanned with a 3-Tesla MRI scanner while viewing six types of video clips: observation of gait movement (GO) from the third-person perspective, observation of stepping movement, observation of standing posture, "virtual walki...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.03.010

    authors： Iseki K,Hanakawa T,Shinozaki J,Nankaku M,Fukuyama H

    更新日期：2008-07-01 00:00:00

  • Heart rate variability is associated with amygdala functional connectivity with MPFC across younger and older adults.

    abstract：:The ability to regulate emotion is crucial to promote well-being. Evidence suggests that the medial prefrontal cortex (mPFC) and adjacent anterior cingulate (ACC) modulate amygdala activity during emotion regulation. Yet less is known about whether the amygdala-mPFC circuit is linked with regulation of the autonomic n...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.05.076

    authors： Sakaki M,Yoo HJ,Nga L,Lee TH,Thayer JF,Mather M

    更新日期：2016-10-01 00:00:00

  • Symbolic action priming relies on intact neural transmission along the retino-geniculo-striate pathway.

    abstract：:Recent psychophysics studies suggest that the behavioral impact of a visual stimulus and its conscious visual recognition underlie two functionally dissociated neuronal processes. Previous TMS studies have demonstrated that certain features of a visual stimulus can still be processed despite TMS-induced disruption of ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.07.030

    authors： Sack AT,van der Mark S,Schuhmann T,Schwarzbach J,Goebel R

    更新日期：2009-01-01 00:00:00

  • Detecting stable individual differences in the functional organization of the human basal ganglia.

    abstract：:Moving from group level to individual level functional parcellation maps is a critical step for developing a rich understanding of the links between individual variation in functional network architecture and cognitive and clinical phenotypes. Still, the identification of functional units in the brain based on intrins...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.07.029

    authors： Garcia-Garcia M,Nikolaidis A,Bellec P,Craddock RC,Cheung B,Castellanos FX,Milham MP

    更新日期：2018-04-15 00:00:00

  • Cognitive emotion regulation enhances aversive prediction error activity while reducing emotional responses.

    abstract：:Cognitive emotion regulation is a powerful way of modulating emotional responses. However, despite the vital role of emotions in learning, it is unknown whether the effect of cognitive emotion regulation also extends to the modulation of learning. Computational models indicate prediction error activity, typically obse...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.08.038

    authors： Mulej Bratec S,Xie X,Schmid G,Doll A,Schilbach L,Zimmer C,Wohlschläger A,Riedl V,Sorg C

    更新日期：2015-12-01 00:00:00

  • Cortical control of normal gait and precision stepping: an fNIRS study.

    abstract：:Recently, real time imaging of the cortical control of gait became possible with functional near-infrared spectroscopy (fNIRS). So far, little is known about the activations of various cortical areas in more complex forms of gait, such as precision stepping. From previous work on animals and humans one would expect pr...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.04.070

    authors： Koenraadt KL,Roelofsen EG,Duysens J,Keijsers NL

    更新日期：2014-01-15 00:00:00

  • Size and probability of rewards modulate the feedback error-related negativity associated with wins but not losses in a monetarily rewarded gambling task.

    abstract：:Feedback error-related negativity (fERN) has been referred to as a negative deflection in the event related potential (ERP), which distinguishes between wins and losses in terms of expected and unexpected outcomes. Some studies refer to the "expected outcome" as the probability to win vs. to lose, and others as expect...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.03.031

    authors： San Martín R,Manes F,Hurtado E,Isla P,Ibañez A

    更新日期：2010-07-01 00:00:00

  • Dynamic changes in the cerebral metabolic rate of O2 and oxygen extraction ratio in event-related functional MRI.

    abstract：:Dynamic changes in the cerebral metabolic rate of oxygen (CMRO(2)) and oxygen extraction ratio (OER) in an event-related functional MRI (ER-fMRI) were measured in this study. Six subjects participated in this study at a magnetic field of 1.9 T. Cerebral blood flow (CBF) and blood oxygenation level-dependent (BOLD) cha...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/s1053-8119(02)00023-x

    authors： Feng CM,Liu HL,Fox PT,Gao JH

    更新日期：2003-02-01 00:00:00

  • Distinct encoding of risk and value in economic choice between multiple risky options.

    abstract：:Neural encoding of value-based stimuli is suggested to involve representations of summary statistics, including risk and expected value (EV). A more complex, but ecologically more common, context is when multiple risky options are evaluated together. However, it is unknown whether encoding related to option evaluation...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.05.023

    authors： Wright ND,Symmonds M,Dolan RJ

    更新日期：2013-11-01 00:00:00

  • Reference-free removal of EEG-fMRI ballistocardiogram artifacts with harmonic regression.

    abstract：:Combining electroencephalogram (EEG) recording and functional magnetic resonance imaging (fMRI) offers the potential for imaging brain activity with high spatial and temporal resolution. This potential remains limited by the significant ballistocardiogram (BCG) artifacts induced in the EEG by cardiac pulsation-related...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.06.088

    authors： Krishnaswamy P,Bonmassar G,Poulsen C,Pierce ET,Purdon PL,Brown EN

    更新日期：2016-03-01 00:00:00

  • Theta-burst stimulation: remote physiological and local behavioral after-effects.

    abstract：:Theta-burst stimulation (TBS), a novel repetitive transcranial magnetic stimulation (TMS) protocol, is capable of suppressing the amplitude of contralateral motor-evoked potentials (MEP) for several minutes after the end of a conditioning train over the motor cortex. It remains unknown whether TBS leads to effects on ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.11.037

    authors： Stefan K,Gentner R,Zeller D,Dang S,Classen J

    更新日期：2008-03-01 00:00:00

  • Cortical dynamics during preparation and execution of reactive balance responses with distinct postural demands.

    abstract：:The contributions of the cerebral cortex to human balance control are clearly demonstrated by the profound impact of cortical lesions on the ability to maintain standing balance. The cerebral cortex is thought to regulate subcortical postural centers to maintain upright balance and posture under varying environmental ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.12.045

    authors： Solis-Escalante T,van der Cruijsen J,de Kam D,van Kordelaar J,Weerdesteyn V,Schouten AC

    更新日期：2019-03-01 00:00:00

  • Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: findings from the Alzheimer's Disease Neuroimaging Initiative.

    abstract：:Alzheimer's disease (AD) is characterized by specific and progressive reductions in fluorodeoxyglucose positron emission tomography (FDG PET) measurements of the cerebral metabolic rate for glucose (CMRgl), some of which may precede the onset of symptoms. In this report, we describe twelve-month CMRgl declines in 69 p...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.02.064

    authors： Chen K,Langbaum JB,Fleisher AS,Ayutyanont N,Reschke C,Lee W,Liu X,Bandy D,Alexander GE,Thompson PM,Foster NL,Harvey DJ,de Leon MJ,Koeppe RA,Jagust WJ,Weiner MW,Reiman EM,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2010-06-01 00:00:00

  • Early childhood development of white matter fiber density and morphology.

    abstract：:Early childhood is an important period for cognitive and brain development, though white matter changes specific to this period remain understudied. Here we utilize a novel analytic approach to quantify and track developmental changes in white matter micro- and macro-structure, calculated from individually oriented fi...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.116552

    authors： Dimond D,Rohr CS,Smith RE,Dhollander T,Cho I,Lebel C,Dewey D,Connelly A,Bray S

    更新日期：2020-04-15 00:00:00

  • Quantifying inter-subject agreement in brain-imaging analyses.

    abstract：:In brain-imaging research, we are often interested in making quantitative claims about effects across subjects. Given that most imaging data consist of tens to thousands of spatially correlated time series, inter-subject comparisons are typically accomplished with simple combinations of inter-subject data, for example...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.07.064

    authors： Wong DK,Grosenick L,Uy ET,Perreau Guimaraes M,Carvalhaes CG,Desain P,Suppes P

    更新日期：2008-02-01 00:00:00