Allograft theory: transmission of devil facial-tumour disease.

abstract：:Shear stress is a fundamental determinant of vascular homeostasis, regulating vascular remodelling, cardiac development and atherogenesis, but the mechanisms of transduction are poorly understood. Previous work showed that the conversion of integrins to a high-affinity state mediates a subset of shear responses, inclu...

journal_title：Nature

authors： Tzima E,Irani-Tehrani M,Kiosses WB,Dejana E,Schultz DA,Engelhardt B,Cao G,DeLisser H,Schwartz MA

更新日期：2005-09-15 00:00:00

abstract：:High-temperature superconductivity is achieved by doping copper oxide insulators with charge carriers. The density of carriers in conducting materials can be determined from measurements of the Hall voltage--the voltage transverse to the flow of the electrical current that is proportional to an applied magnetic field....

journal_title：Nature

authors： Balakirev FF,Betts JB,Migliori A,Ono S,Ando Y,Boebinger GS

更新日期：2003-08-21 00:00:00

abstract：:The Environmental Protection Agency is preparing to regulate the biotechnology industry, claiming authority under the provisions of the Federal Toxic Substances Control Act (TOSCA) and the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). In the agency's view, the products of recombinant DNA techniques can...

journal_title：Nature

authors： Earl C

更新日期：1983-11-03 00:00:00

abstract：:Phosphorylation of membrane components is thought to be an important process in membrane function. Phosphorylated proteins and a special class of phospholipids, the (poly)phosphoinositides (poly PI), are implicated in the regulation of membrane permeability and synaptic transmission in neurones. For many years, protei...

journal_title：Nature

authors： Jolles J,Zwiers H,van Dongen CJ,Schotman P,Wirtz KW,Gispen WH

更新日期：1980-08-07 00:00:00

abstract：:In Fig. 3d this Letter, the R2 value should have been '0.19' instead of '0.66'; this has been corrected online. ...

journal_title：Nature

authors： Hoyt JR,Langwig KE,White JP,Kaarakka HM,Redell JA,Kurta A,DePue JE,Scullon WH,Parise KL,Foster JT,Frick WF,Kilpatrick AM

更新日期：2019-02-01 00:00:00

abstract：:An emerging concept in the field of cancer biology is that a rare population of 'tumour stem cells' exists among the heterogeneous group of cells that constitute a tumour. This concept, best described with human leukaemia, indicates that stem cell function (whether normal or neoplastic) might be defined by a common se...

journal_title：Nature

authors： Lessard J,Sauvageau G

更新日期：2003-05-15 00:00:00

abstract：:Optical laser fields have been widely used to achieve quantum control over the motional and internal degrees of freedom of atoms and ions, molecules and atomic gases. A route to controlling the quantum states of macroscopic mechanical oscillators in a similar fashion is to exploit the parametric coupling between optic...

journal_title：Nature

authors： Verhagen E,Deléglise S,Weis S,Schliesser A,Kippenberg TJ

更新日期：2012-02-01 00:00:00

abstract：:Magnetars are neutron stars with X-ray and soft γ-ray outbursts thought to be powered by intense internal magnetic fields. Like conventional neutron stars in the form of radio pulsars, magnetars exhibit 'glitches' during which angular momentum is believed to be transferred between the solid outer crust and the superfl...

journal_title：Nature

authors： Archibald RF,Kaspi VM,Ng CY,Gourgouliatos KN,Tsang D,Scholz P,Beardmore AP,Gehrels N,Kennea JA

更新日期：2013-05-30 00:00:00

abstract：:Gut microbes supply the human body with energy from dietary polysaccharides through carbohydrate active enzymes, or CAZymes, which are absent in the human genome. These enzymes target polysaccharides from terrestrial plants that dominated diet throughout human evolution. The array of CAZymes in gut microbes is highly ...

journal_title：Nature

authors： Hehemann JH,Correc G,Barbeyron T,Helbert W,Czjzek M,Michel G

更新日期：2010-04-08 00:00:00

abstract：:The tropical forests of Borneo and Amazonia may each contain more tree species diversity in half a square kilometre than do all the temperate forests of Europe, North America, and Asia combined. Biologists have long been fascinated by this disparity, using it to investigate potential drivers of biodiversity. Latitudin...

journal_title：Nature

authors： Usinowicz J,Chang-Yang CH,Chen YY,Clark JS,Fletcher C,Garwood NC,Hao Z,Johnstone J,Lin Y,Metz MR,Masaki T,Nakashizuka T,Sun IF,Valencia R,Wang Y,Zimmerman JK,Ives AR,Wright SJ

更新日期：2017-10-05 00:00:00

abstract：:One reason for the failure of chemotherapy in the treatment of advanced cancers may be the outgrowth of multidrug-resistant tumour cells. Multidrug resistance has been modelled in numerous mammalian cell lines in which the phenotype is characterized by a pleiotropic cross-resistance to unrelated drugs. In the study re...

journal_title：Nature

authors： Kartner N,Evernden-Porelle D,Bradley G,Ling V

更新日期：1985-08-29 00:00:00

abstract：:Granular materials and ordinary fluids react differently to shear stresses. Rather than deforming uniformly, materials such as dry sand or cohesionless powders develop shear bands--narrow zones of large relative particle motion, with essentially rigid adjacent regions. Because shear bands mark areas of flow, material ...

journal_title：Nature

authors： Mueth DM,Debregeas GF,Karczmar GS,Eng PJ,Nagel SR,Jaeger HM

更新日期：2000-07-27 00:00:00

abstract：:Many collective human activities, including violence, have been shown to exhibit universal patterns. The size distributions of casualties both in whole wars from 1816 to 1980 and terrorist attacks have separately been shown to follow approximate power-law distributions. However, the possibility of universal patterns r...

journal_title：Nature

authors： Bohorquez JC,Gourley S,Dixon AR,Spagat M,Johnson NF

更新日期：2009-12-17 00:00:00

abstract：:The recent discovery of CD4(+) T cells characterized by secretion of interleukin (IL)-17 (T(H)17 cells) and the naturally occurring regulatory FOXP3(+) CD4 T cell (nT(reg)) has had a major impact on our understanding of immune processes not readily explained by the T(H)1/T(H)2 paradigm. T(H)17 and nT(reg) cells have b...

journal_title：Nature

authors： Yang L,Anderson DE,Baecher-Allan C,Hastings WD,Bettelli E,Oukka M,Kuchroo VK,Hafler DA

更新日期：2008-07-17 00:00:00

abstract：:Accurate measurement of the lifetime of the neutron (which is unstable to beta decay) is important for understanding the weak nuclear force and the creation of matter during the Big Bang. Previous measurements of the neutron lifetime have mainly been limited by certain systematic errors; however, these could in princi...

journal_title：Nature

authors： Huffman PR,Brome CR,Butterworth JS,Coakley KJ,Dewey MS,Dzhosyuk SN,Golub R,Greene GL,Habicht K,Lamoreaux SK,Mattoni CE,McKinsey DN,Wietfeldt FE,Doyle JM

更新日期：2000-01-06 00:00:00

abstract：:Sensory systems can adapt to the conditions imposed on them. In the visual system, adapting to a pattern increases the threshold of the ability to see that pattern, and reduces the perceived contrast of the pattern above threshold. Most neurons of the striate cortex reduce their responsiveness after being stimulated f...

journal_title：Nature

authors： Snowden RJ,Hammett ST

更新日期：1992-01-16 00:00:00

abstract：:In developed societies, chronic diseases such as diabetes, obesity, atherosclerosis and cancer are responsible for most deaths. These ailments have complex causes involving genetic, environmental and nutritional factors. There is evidence that a group of closely related nuclear receptors, called peroxisome proliferato...

journal_title：Nature

authors： Kersten S,Desvergne B,Wahli W

更新日期：2000-05-25 00:00:00

abstract：:Nitrogen enrichment is widely thought to be responsible for the loss of plant species from temperate terrestrial ecosystems. This view is based on field surveys and controlled experiments showing that species richness correlates negatively with high productivity and nitrogen enrichment. However, as the type of nutrien...

journal_title：Nature

authors： Wassen MJ,Venterink HO,Lapshina ED,Tanneberger F

更新日期：2005-09-22 00:00:00

abstract：:The spindle checkpoint prevents chromosome mis-segregation by delaying sister chromatid separation until all chromosomes have achieved bipolar attachment to the mitotic spindle. Its operation is essential for accurate chromosome segregation, whereas its dysregulation can contribute to birth defects and tumorigenesis. ...

journal_title：Nature

authors： Stegmeier F,Rape M,Draviam VM,Nalepa G,Sowa ME,Ang XL,McDonald ER 3rd,Li MZ,Hannon GJ,Sorger PK,Kirschner MW,Harper JW,Elledge SJ

更新日期：2007-04-19 00:00:00

abstract：:Arbuscular mycorrhizal (AM) fungi (Glomeromycota) reproduce asexually, are multinucleate, and have high genetic variation within single cells. Pawlowska and Taylor find that genetic variation within AM fungal cells is not lost as a result of segregation, and they interpret this as evidence that the variation is presen...

journal_title：Nature

authors： Bever JD,Wang M

更新日期：2005-01-13 00:00:00

abstract：:The University of California at Berkeley has announced the postponement of a planned experiment involving the field testing of bacteria genetically engineered to reduce frost damage to crops. The action came after Jeremy Rifkin, who had earlier filed suit against the National Institutes of Health after its Recombinan...

journal_title：Nature

authors： Budiansky S

更新日期：1983-10-13 00:00:00

abstract：:Soybean (Glycine max (L.) Merr.) is an important crop that provides a sustainable source of protein and oil worldwide. Soybean cyst nematode (Heterodera glycines Ichinohe) is a microscopic roundworm that feeds on the roots of soybean and is a major constraint to soybean production. This nematode causes more than US$1 ...

journal_title：Nature

authors： Liu S,Kandoth PK,Warren SD,Yeckel G,Heinz R,Alden J,Yang C,Jamai A,El-Mellouki T,Juvale PS,Hill J,Baum TJ,Cianzio S,Whitham SA,Korkin D,Mitchum MG,Meksem K

更新日期：2012-12-13 00:00:00

abstract：:Oocytes arrested in the G2 phase of the cell cycle contain a p34cdc2/cyclin B complex which is kept in an inactive form by phosphorylation of its p34cdc2 subunit on tyrosine, threonine and perhaps serine residues. The phosphatase(s) involved in p34cdc2 dephosphorylation is unknown, but the product of the fission yeast...

journal_title：Nature

authors： Strausfeld U,Labbé JC,Fesquet D,Cavadore JC,Picard A,Sadhu K,Russell P,Dorée M

更新日期：1991-05-16 00:00:00

abstract：:Human behaviour is thought to spread through face-to-face social networks, but it is difficult to identify social influence effects in observational studies, and it is unknown whether online social networks operate in the same way. Here we report results from a randomized controlled trial of political mobilization mes...

journal_title：Nature

authors： Bond RM,Fariss CJ,Jones JJ,Kramer AD,Marlow C,Settle JE,Fowler JH

更新日期：2012-09-13 00:00:00

abstract：:FokI is a member of an unusual class of bipartite restriction enzymes that recognize a specific DNA sequence and cleave DNA nonspecifically a short distance away from that sequence. Because of its unusual bipartite nature, FokI has been used to create artificial enzymes with new specificities. We have determined the c...

journal_title：Nature

authors： Wah DA,Hirsch JA,Dorner LF,Schildkraut I,Aggarwal AK

更新日期：1997-07-03 00:00:00

abstract：:The rapid turnover of the mammalian intestinal epithelium is supported by stem cells located around the base of the crypt. In addition to the Lgr5 marker, intestinal stem cells have been associated with other markers that are expressed heterogeneously within the crypt base region. Previous quantitative clonal fate ana...

journal_title：Nature

authors： Ritsma L,Ellenbroek SIJ,Zomer A,Snippert HJ,de Sauvage FJ,Simons BD,Clevers H,van Rheenen J

更新日期：2014-03-20 00:00:00

abstract：:The induction of polyarthritis in rats by intradermal immunisation with homologous or heterologous type II collagen incomplete or incomplete Freund's adjuvant was reported recently by Trentham et al. We have now produced a similar disease in certain strains of mice. ...

journal_title：Nature

authors： Courtenay JS,Dallman MJ,Dayan AD,Martin A,Mosedale B

更新日期：1980-02-14 00:00:00

abstract：:The foundation of western civilization owes much to the high fertility of bread wheat, which results from the stability of its polyploid genome. Despite possessing multiple sets of related chromosomes, hexaploid (bread) and tetraploid (pasta) wheat both behave as diploids at meiosis. Correct pairing of homologous chro...

journal_title：Nature

authors： Griffiths S,Sharp R,Foote TN,Bertin I,Wanous M,Reader S,Colas I,Moore G

更新日期：2006-02-09 00:00:00

abstract：:Large-conductance (BK type) Ca(2+)-dependent K(+) channels are essential for modulating muscle contraction and neuronal activities such as synaptic transmission and hearing. BK channels are activated by membrane depolarization and intracellular Ca(2+) and Mg(2+) (refs 6-10). The energy provided by voltage, Ca(2+) and ...

journal_title：Nature

authors： Shi J,Krishnamoorthy G,Yang Y,Hu L,Chaturvedi N,Harilal D,Qin J,Cui J

更新日期：2002-08-22 00:00:00

abstract：:The existence of so great a diversity of species on Earth remains a mystery, the solution to which may also explain why and how biodiversity influences the functioning of ecosystems. The answer may lie in quantifying the trade-offs that organisms face in dealing with the constraints of their environment. Societal resp...

journal_title：Nature

authors： Tilman D

更新日期：2000-05-11 00:00:00