Abstract:
:In this article, a mechanism of arsenite [As(III)]resistance through methylation and subsequent volatization is described. Heterologous expression of arsM from Rhodopseudomonas palustris was shown to confer As(III) resistance to an arsenic-sensitive strain of Escherichia coli. ArsM catalyzes the formation of a number of methylated intermediates from As(III), with trimethylarsine as the end product. The net result is loss of arsenic, from both the medium and the cells. Because ArsM homologues are widespread in nature, this microbial-mediated transformation is proposed to have an important impact on the global arsenic cycle.
journal_name
Proc Natl Acad Sci U S Aauthors
Qin J,Rosen BP,Zhang Y,Wang G,Franke S,Rensing Cdoi
10.1073/pnas.0506836103keywords:
subject
Has Abstractpub_date
2006-02-14 00:00:00pages
2075-80issue
7eissn
0027-8424issn
1091-6490pii
0506836103journal_volume
103pub_type
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