Therapy-related lymphomas in patients with autoimmune diseases after treatment with disease-modifying anti-rheumatic drugs.

abstract：:Although infectious complications represent a relevant cause of morbidity and mortality in patients with myelofibrosis (MF), little is known about their incidence, outcome and risk factors. We retrospectively evaluated a cohort of 507 MF patients, diagnosed between 1980 and 2014 in five Italian hematology centers, to ...

journal_title：American journal of hematology

authors： Polverelli N,Breccia M,Benevolo G,Martino B,Tieghi A,Latagliata R,Sabattini E,Riminucci M,Godio L,Catani L,Nicolosi M,Perricone M,Sollazzo D,Colafigli G,Campana A,Merli F,Vitolo U,Alimena G,Martinelli G,Lewis RE,V

更新日期：2017-01-01 00:00:00

abstract：:The FAB classification of myelodysplastic syndromes (MDS) has been useful in predicting prognosis; however, additional methods are required to detect patients at high risk for early conversion to acute nonlymphoblastic leukemia (ANLL). Using a panel of monoclonal antibodies to myelomonocytic surface antigens (MMSA) an...

journal_title：American journal of hematology

authors： Mittelman M,Karcher DS,Kammerman LA,Lessin LS

更新日期：1993-07-01 00:00:00

abstract：:Eosinophilia associated with solid tumors is an infrequent occurrence. The pathogenesis of tumor-associated eosinophilia is not well understood. Interleukin-5 (IL-5) is a cytokine that has been implicated in the development of eosinophilia in mice and humans. However, there is little data associating IL-5 production w...

journal_title：American journal of hematology

authors： Pandit R,Scholnik A,Wulfekuhler L,Dimitrov N

更新日期：2007-03-01 00:00:00

abstract：:A case of leukemia cutis (LC) of monocytic lineage in a patient with myelodysplastic syndrome (MDS) is presented. Cutaneous infiltrates were recognized concurrent with diagnosis of refractory anemia (RA) with monocytosis. Skin infiltrates subsequently spontaneously regressed although MDS progressed with increasing mon...

journal_title：American journal of hematology

authors： Yavorkovsky LL,Zain J,Wu CD,Trivelli L,Cook P

更新日期：2001-02-01 00:00:00

abstract：:Intensive induction chemotherapy using anthracycline and cytarabine backbone is considered the most effective upfront therapy in physically fit older patients with acute myeloid leukemia (AML). However, outcomes of the standard induction in elderly AML are inferior to those observed in younger patients, and they are s...

journal_title：American journal of hematology

authors： Pluta A,Robak T,Wrzesien-Kus A,Katarzyna Budziszewska B,Sulek K,Wawrzyniak E,Czemerska M,Zwolinska M,Golos A,Holowiecka-Goral A,Kyrcz-Krzemien S,Piszcz J,Kloczko J,Mordak-Domagala M,Lange A,Razny M,Madry K,Wiktor-Jedrze

更新日期：2017-04-01 00:00:00

abstract：:We investigated the rare case of a patient with IgGlambda multiple myeloma for whom both prothrombin time and APTT were significantly prolonged. The IgG inhibited coagulation reactions upstream from prothrombin when coagulation was initiated by mRVVT, but not by FXa, as indicated by a chromogenic substrate for FXa. Th...

journal_title：American journal of hematology

authors： Takamiya O,Machida S,Okuda M,Nojima J,Koreeda C,Kubara K

更新日期：2004-01-01 00:00:00

abstract：:Non-Hodgkin lymphoma arising in the context of immunosuppression is an important adverse outcome after solid organ transplantation. Diffuse large B-cell lymphoma (DLBCL) is the most commonly diagnosed subtype of post-transplantation non-Hodgkin lymphoma, but few studies of transplant recipients have examined subtype-s...

journal_title：American journal of hematology

authors： Gibson TM,Engels EA,Clarke CA,Lynch CF,Weisenburger DD,Morton LM

更新日期：2014-07-01 00:00:00

abstract：:We describe 3 episodes of microangiopathic hemolytic anemia (MAHA) in 2 solid organ recipients under FK506 (tacrolimus) therapy. In both cases, discontinuation of FK506 and treatment with plasma exchange, fresh frozen plasma replacement, corticosteroids, aspirin, and dipyridamole led to resolution of MAHA. In one pati...

journal_title：American journal of hematology

authors： Mach-Pascual S,Samii K,Beris P

更新日期：1996-08-01 00:00:00

abstract：:New treatments have transformed multiple myeloma into a chronic disease. Hence, optimal management of treatment and disease-related complications remains a critical component of survivorship care. Survivorship care model in cancers requiring a fixed-duration therapy may not be applicable to myeloma, since patients are...

journal_title：American journal of hematology

authors： Chakraborty R,Majhail NS

更新日期：2020-06-01 00:00:00

abstract：:A case of idiopathic myelofibrosis (IMF) presenting with hypercalcemia and hypercalcitriolemia is reported. It is proposed that ectopic production of the active vitamin D metabolite related to ongoing clonal expansion in the bone marrow accounts for the hypercalcemic state. Consistently low levels of circulating type ...

journal_title：American journal of hematology

authors： Voss A,Schmidt K,Hasselbalch H,Junker P

更新日期：1992-03-01 00:00:00

abstract：:Mast cell disease (MCD), a proliferation of mast cells (MC), is occasionally associated with hematologic malignancies. Neoplastic MC have activating c-kit mutations. c-kit is a receptor tyrosine kinase required for the development, proliferation, and survival of MC. Interaction of c-kit with its ligand stem cell facto...

journal_title：American journal of hematology

authors： Pullarkat VA,Pullarkat ST,Calverley DC,Brynes RK

更新日期：2000-12-01 00:00:00

abstract：:The objective of this case-matched study was to compare the efficacy and toxicity of the addition of clarithromycin (Biaxin) to lenalidomide/low-dose dexamethasone (BiRd) vs. lenalidomide/low-dose dexamethasone (Rd) for newly diagnosed myeloma. Data from 72 patients treated at the New York Presbyterian Hospital-Cornel...

journal_title：American journal of hematology

authors： Gay F,Rajkumar SV,Coleman M,Kumar S,Mark T,Dispenzieri A,Pearse R,Gertz MA,Leonard J,Lacy MQ,Chen-Kiang S,Roy V,Jayabalan DS,Lust JA,Witzig TE,Fonseca R,Kyle RA,Greipp PR,Stewart AK,Niesvizky R

更新日期：2010-09-01 00:00:00

abstract：:Most cases of immune hemolytic anemia are associated with a positive direct antiglobulin test. However, in some cases, the antiglobulin test is not sensitive enough to detect low levels of red-cell bound antibodies. This report describes a method using radiolabelled purified staphylococcal protein A which is capable o...

journal_title：American journal of hematology

authors： Yam P,Petz LD,Spath P

更新日期：1982-06-01 00:00:00

abstract：:During the 5-year period from 1981 to 1985, we have observed 8 cases of acquired immunodeficiency syndrome (AIDS) among our 85 patients with hemophilia A. Thus, the prevalence of AIDS with hemophilia A is 9.4% in our patient population. By utilizing stored serum or plasma samples dating back to 1978, antibody against ...

journal_title：American journal of hematology

authors： Kim HC,Nahum K,Raska K Jr,Gocke DJ,Kosmin M,Karp GI,Saidi P

更新日期：1987-02-01 00:00:00

abstract：:Because of the T-cell abnormalities observed in Hodgkin's disease and the growing number of Hodgkin's disease cases observed in association with the acquired immunodeficiency syndrome (AIDS), concern has been expressed that a retrovirus may be the primary cause of Hodgkin's disease. We examined plasma specimens from 1...

journal_title：American journal of hematology

authors： Chorba TL,Kalyanaraman VS,Lacher MJ,Schulof RS

更新日期：1988-01-01 00:00:00

abstract：:The relationship between thrombocytopenia and the level of anticardiolipin antibodies (aCL) and/or the existence of lupus anticoagulant (LA) ware studied in 146 patients with systemic lupus erythematosus (SLE). These patients were divided into six groups: A, those LA positive with a high level of aCL (>10 U/ml) (10 ca...

journal_title：American journal of hematology

authors： Nojima J,Suehisa E,Kuratsune H,Machii T,Toku M,Tada H,Yamaguti K,Koike T,Kanakura Y,Kitani T,Amino N

更新日期：1998-05-01 00:00:00

abstract：:Immunoglobulin light-chain amyloidosis (AL) is a rare disorder characterized by production of a monoclonal light chain. This insoluble light chain, or a fragment thereof, deposits in tissues as amyloid and results in disruption of organ function and, ultimately, in death. Although melphalan and prednisone are benefici...

journal_title：American journal of hematology

authors： Gertz MA,Lacy MQ,Lust JA,Greipp PR,Witzig TE,Kyle RA

更新日期：1999-06-01 00:00:00

abstract：:A 67-year-old woman was admitted to our hospital because of lymphadenopathy and lymphocytosis. Monoclonal integration of HTLV-I provirus DNA was detected, and a diagnosis of adult T-cell leukemia (ATL) was made. Flow cytometry revealed that the ATL cells expressed CD20 as well as T-cell-associated antigens, and expres...

journal_title：American journal of hematology

authors： Yasukawa M,Arai J,Kakimoto M,Sakai I,Kohno H,Fujita S

更新日期：2001-01-01 00:00:00

abstract：:A patient with Philadelphia chromosome (Ph) chronic myelogenous leukemia (CML), in chronic phase, was treated with recombinant gamma-interferon (r gamma-IFN) in a phase I clinical trial. Prior to treatment, analysis of in vitro agar culture parameters indicated hyporesponsiveness of granulocyte-macrophage colony-formi...

journal_title：American journal of hematology

authors： Pelus LM,Vadhan-Raj S

更新日期：1988-05-01 00:00:00

abstract：:Over a 36-month period, 46 consecutive Mexican mestizos with a clinical marker associated with a primary hypercoagulable state were prospectively assessed by searching for the sticky platelet syndrome (SPS), the activated protein C resistance (aPCR) phenotype, coagulation protein C activity and antigen, coagulation pr...

journal_title：American journal of hematology

authors： Ruiz-Argüelles GJ,López-Martínez B,Valdés-Tapia P,Gómez-Rangel JD,Reyes-Núñez V,Garcés-Eisele J

更新日期：2005-01-01 00:00:00

abstract：DISEASE OVERVIEW:Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) characterized by stem cell-derived clonal myeloproliferation that is often but not always accompanied by JAK2, CALR, or MPL mutations; additional disease features include bone marrow stromal reaction including reticulin fibrosis, abnorm...

journal_title：American journal of hematology

authors： Tefferi A

更新日期：2018-12-01 00:00:00

abstract：:Withdrawal: Primary prevention of sickle cell disease using preimplantation genetic testing and in vitro fertilization is cost-effective. The above article, published online on 20 August 2020 in Wiley Online Library (wileyonlinelibrary.com) as an Accepted Article, has been withdrawn by agreement between the authors, t...

journal_title：American journal of hematology

authors： Cordeiro Mitchell CN,Pradhan A,Singh B,Naik RP,Baker VL,Lanzkron SM,Christianson MS,Pecker LH

更新日期：2020-08-20 00:00:00

abstract：:A 56-year-old man was admitted to our hospital with leukocytosis, anemia, and thrombocytopenia. Acute monoblastic leukemia was diagnosed. Two subsequent courses of consolidation chemotherapy consisted of conventional doses of cytarabine and intermediate-dose cytarabine. Intermediate-dose cytarabine was infused intrave...

journal_title：American journal of hematology

authors： Saito B,Nakamaki T,Nakashima H,Usui T,Hattori N,Kawakami K,Tomoyasu S

更新日期：2007-04-01 00:00:00

abstract：:We report a 45-year-old female patient with recurrent spontaneous deep vein thrombosis associated with an isolated hypoplasminogenemia (plasminogen activity and antigen level of 42% and 37%, respectively). The plasminogen molecule was normal as demonstrated by a normal activation by tissue plasminogen activator, elect...

journal_title：American journal of hematology

authors： Leebeek FW,Knot EA,Ten Cate JW,Traas DW

更新日期：1989-01-01 00:00:00

abstract：:Cerebrospinal fluid beta-2-microglobulin (CSF-beta 2m) was measured longitudinally in 48 patients affected by acute lymphoblastic leukemia (ALL). Thirteen developed a central nervous system (CNS) involvement during the course of the disease; although moderately higher mean CSF-beta 2m levels were found in these subjec...

journal_title：American journal of hematology

authors： Musto P,Tomasi P,Cascavilla N,Ladogana S,La Sala A,Melillo L,Nobile M,Castoldi G,Carotenuto M

更新日期：1988-08-01 00:00:00

abstract：:Reversible posterior leukoencephalopathy syndrome (RPLS) is an uncommon but distinctive clinicoradiological entity comprising of headache, seizures, visual disturbance, and altered mental function, in association with posterior cerebral white matter edema. With appropriate management, RPLS is reversible in the majorit...

journal_title：American journal of hematology

authors： Tam CS,Galanos J,Seymour JF,Pitman AG,Stark RJ,Prince HM

更新日期：2004-09-01 00:00:00

abstract：:"Autonomous" development of erythroid colonies in erythropoietin (EPO)-free semi-solid culture has been used as an in vitro assay for diagnosis of polycythemia vera (PV). These colonies, however, are small and poorly hemoglobinized, rendering the assay in many cases unreliable. We report here on the use of a novel ass...

journal_title：American journal of hematology

authors： Manor D,Rachmilewitz EA,Fibach E

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The histopathologic features characterizing the involvement of the bone marrow (BM) in systemic lupus erythematosus (SLE) have not been systematically analyzed to date. OBJECTIVES:The aim of this study was to assess morphologic and immunohistochemical characteristics of BM involvement in SLE. PATIENTS AND ...

journal_title：American journal of hematology

authors： Voulgarelis M,Giannouli S,Tasidou A,Anagnostou D,Ziakas PD,Tzioufas AG

更新日期：2006-08-01 00:00:00

abstract：:We have investigated the methods for the maintenance of a pregnancy in a patient with thrombotic thrombocytopenic purpura (TTP), said condition, since 1984, having been controlled by a plasma infusion every 3 to 4 weeks. In a preliminary trial it was confirmed that an infusion of the high molecular weight fraction (HM...

journal_title：American journal of hematology

authors： Koyama T,Suehiro A,Kakishita E,Taira S,Isojima S,Norioka M,Ito K

更新日期：1990-11-01 00:00:00

abstract：:Duvelisib (IPI-145), an oral, dual inhibitor of phosphoinositide-3-kinase (PI3K)-δ and -γ, was evaluated in a Phase 1 study in advanced hematologic malignancies, which included expansion cohorts in relapsed/refractory (RR) chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) and treatment-naïve (TN) CLL...

journal_title：American journal of hematology

authors： O'Brien S,Patel M,Kahl BS,Horwitz SM,Foss FM,Porcu P,Jones J,Burger J,Jain N,Allen K,Faia K,Douglas M,Stern HM,Sweeney J,Kelly P,Kelly V,Flinn I

更新日期：2018-11-01 00:00:00