Abstract：
:The efficacy and safety of the treatment of arterial hypertension with the ACE-inhibitor quinapril, were evaluated in a multicentre study conducted in Italy. The study, lasting 14 weeks, after a preliminary wash-out period, allowed response-based titration of quinapril dose from 10 mg to 40 mg once a day, with provision to combine additional hydrochlorothiazide (12.5 to 25 mg), in case of persistently high diastolic pressure levels. The efficacy sample included 1267 patients: at therapy week 14, 78.6% of patients were treated with quinapril alone. Global response rate (intent-to-treat) was 83.3%, with a mean reduction of diastolic pressure of 15.8 mmHg (95% confidence interval from 15.5 to 16.2 mmHg). 91 patients reported 126 associated adverse events (7.0%); the most frequently reported event was cough (2.7%). First-dose hypotension was rarely reported (1.3%), even in elderly and diabetic patients.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Ambrosioni E,Brusca A,Caponnetto S,Condorelli M,Corea L,Dal Palù C,Fogari R,Mameli P,Mancia G,Neri Serneri GGkeywords:
subject
Has Abstract,Author List Incompletepub_date
1992-03-01 00:00:00pages
85-96issue
3eissn
0026-4725issn
1827-1618journal_volume
40pub_type
临床试验,杂志文章,多中心研究abstract：BACKGROUND:Ablation of ventricular tachycardia is the main therapy for patients with drug-refractory VT. Although evidence suggests that VT ablation could lower the incidence of recurrent VT, many cases still develop VT in follow-up. In this study, we performed a systematic review and meta-analysis to examine risk fact...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.20.05128-2
更新日期：2020-09-29 00:00:00
abstract：:Congenital thrombophilia, specifically thrombophilia due to Leiden modified factor V as the cause of thromboembolic disease, is discussed. Thromboembolic disease is potentially fatal and disabling. A clinical case is presented of a girl of 15 with Leiden factor V thrombophilia in which all the typical thromboembolic e...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：AIM:The aim of this study was to analyze restenosis after percutaneous coronary intervention, factors related to restenosis after coronary artery stenting and the degree of the risk of restenosis were evaluated. METHODS:The study enrolled 181 patients (249 lesions) who underwent the first coronary artery stenting. Mul...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:A case is reported of pseudoaneurysm of the right iliac artery secondary to an endarterectomy with dacron patch due to atherosclerosis performed 4 years ago. The case presented acute anemia and massive enteric hemorrhage subsequent to arterial rupture into the cecum. Because of the dramatic onset, the patient was imme...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Deep venous thrombosis (DVT) is often difficult to diagnose based on objective data alone (sensitivity 60-66%, specificity 20-72%, according to a number of studies) and this leads to the possible misuse of instrumental tests. It is important to establish standard clinical protocols to select those cases that call for ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
abstract：:A patent ductus arteriosus in adults is a rare eventuality. After correct diagnosis, an accurate evaluation of pulmonary vascular resistances is necessary with, in case of normality, a straightforward indication to surgery, because the evolution of the disease cannot be predicted. In case of pulmonary hypertension irr...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:The diagnosis of previous non-Q wave myocardial infarction by standard electrocardiographic investigation is uncertain, particularly in elderly patients because of concomitant disease. We have studied 31 elderly patients (aged 63-72 years) with a diagnosis of non-Q wave myocardial infarction between 1-6 months after t...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:In routine clinical practice, a sizeable proportion of patients with suspected coronary artery disease (CAD) undergo coronary angiography without prior non-invasive functional evaluation. In this situation, the decision wheter to perform revascularization is taken solely on the basis of angiographic parameters, which ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2011-02-01 00:00:00
abstract：:The role of routine intravascular ultrasound (IVUS) guidance during percutaneous coronary intervention (PCI) in the bare metal stent era remains controversial. The potential to reduce revascularization was reported without impacting non-fatal myocardial infarction and death. Drug-eluting stents (DES) have realized imp...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2008-02-01 00:00:00
abstract：:As echocardiography is being used more often, its value and accuracy are becoming more fully appreciated, especially for identifying normal anatomic variants and their possible erroneous interpretation as pathologic states. We report the echocardiographic and clinical findings observed in sixteen subjects examined at ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：BACKGROUND:Galectin-3 is a recently developed biomarker of fibrosis, which may play a role in cardiac remodeling and associated with both the progression and severity of heart failure (HF). METHODS:A prospective cohort study of 190 patients with documented prior myocardial infarction and chronic HF (NYHA class II-IV) ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2016-12-01 00:00:00
abstract：:Inflammation is an important contributor to atherothrombosis. The C-reactive protein (CRP) is not only an excellent biomarker of inflammation, but it is also a direct participant in atherogenesis. CRP consistently predicts new coronary events, including myocardial infarction and death, in patients with ischemic heart ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:The aim of this study to investigate the correlation of the peripheral concentrations of one representative estrogen, E2 estradiol, with various indicators reflecting different aspects of cardiac structures and functions. METHODS:A total of 84 typical patients with hypertrophic cardiomyopathy (HCM) and 77 h...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2016-08-01 00:00:00
abstract：:The authors present the results of a research on 3,888 patients (1,768 males and 2,120 females) admitted to the 1st Internal Medicine Department of Leghorn Hospital during two years (from July 1993 to June 1995). The research is intended to value the hyperlipidaemia's incidence in hospitalized patients, and the associ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Personal experience in the management of 70 ruptured abdominal aortic aneurysm over the past 5 years is reported dividing patients into 2 groups, before and after establishment of intensive care unit: survival was 30.76% on the first, 66.66% in the second. Factors that allowed that result are discussed. ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：BACKGROUND:Aim of this study is to estimate the effectiveness of epidural electric stimulation of spinal cord for the treatment of patients with severe peripheral chronic arteriopathy who can't be surgically treated or when surgical therapy failed. METHODS:A retrospective study was carried out on 18 patients with peri...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：AIM:Anthracycline (ANT) chemotherapy for breast cancer, while associated with high response rates, is fraught by risks of irreversible cardiotoxicity. Unfortunately means to detect such cardiotoxicity early on and at a sublinical stage are lacking. We evaluated the role of systolic tissue Doppler imaging (TDI) in appra...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2007-12-01 00:00:00
abstract：:A carotid stenosis is responsible for about 30% of strokes occurring. Carotid endarterectomy (CEA) is considered to be the gold standard treatment of a carotid stenosis. Carotid angioplasty and stenting (CAS) is emerging as a new alternative treatment for a carotid artery stenosis, but the risk of neurological complic...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2007-02-01 00:00:00
abstract：:In presence of a patent foramen ovale (PFO) with cryptogenic cerebral embolism, traditional therapy consists of oral anticoagulation or antiplatelet therapy. Surgery was considered only in case of recurrence. Transcatheter closure of PFO is currently performed. The availability of new user friendly devices and the inc...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
abstract：:Use of definite molecular weight heparan sulphate in a protocol for the prevention of deep venous thrombosis in the total joint replacement surgery. The authors propose a working protocol for the prevention of deep venous thrombosis in prosthetic orthopaedic surgery. It requires that integration of pharmacological, an...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：BACKGROUND:Coronary sinus type atrial defect is the result of an incomplete formation of the atriovenous fold. This is a rare anomaly that in a very few cases took advantage of echocardiographic diagnosis before surgery. We report on a case of coronary sinus type atrial septal defect diagnosed by means of transthoracic...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：:Atrial fibrillation frequently coexists with heart failure, and these two chronic disease states often physiologically exacerbate one another. Clinical trials comparing rate versus rhythm control strategies have not demonstrated superiority with one strategy over the other, with pharmacologically based rhythm manageme...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2008-12-01 00:00:00
abstract：:Intraoperative transesophageal echocardiography (IOTEE) has become an important diagnostic and monitoring tool in the operating theatre during cardiac and noncardiac operations. However, its routine application during valve replacement operations has not received universal recognition. The cumulative experience, broug...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2007-04-01 00:00:00
abstract：:Genetically controlled nitric oxide production is currently assessed mainly by the colorimetric determination of the plasma levels of nitrite/nitrates, specific end-products of NO, or by the magnitude of the vasorelaxation obtained with forearm occlusion venous plethysmography after infusion of stimulating (acetylchol...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
abstract：:Cardiac mixoma in the elderly. A clinical study. The clinical features of 13 cardiac myxomas surgically resected are presented. The mean age at presentation was 68 years. Ten were in the left atrium, 5 near the fossa ovalis, 3 at the base of the atrial septum, 1 at the inferior wall and 1 on the anterior leaflet of mi...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The authors report a 57 year old patient affected by rhinopharyngeal NH lymphoma that appeared as a parapharyngeal space lesions-syncope syndrome. The activation of a cardioinhybitory reflex by the stimulation of the glossopharyngeal nerve seems to be the pathogenetic basis for his syndrome. ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：:In patients with atrial fibrillation (AF) warfarin has been the mainstay therapy for stroke prevention. In recent randomized clinical trials (RCTs) oral direct thrombin inhibitor (Dabigatran) and factor Xa inhibitors (Rivaroxaban and Apixaban) challenged the efficacy and safety benchmarks set by warfarin. These drugs ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:The aim of this prospective supplement summer registry study was to evaluate the efficacy of Pycnogenol® in controlling symptoms of chronic venous insufficiency (CVI) and microcirculatory parameters: venous hypertension and microangiopathy. Pycnogenol® (Horphag Research) is the standardized extract of the ba...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.19.04948-X
更新日期：2019-08-01 00:00:00
abstract：:Cardiac tamponade may be caused by erosion of the right cardiac walls or of the intrapericardial superior vena cava in subjects with a central venous catheter. The underlying cause of this rare complication is direct parietal trauma by the catheter and endarterial damage produced by infused hyperosmolar solutions. Hig...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-12-01 00:00:00
abstract：:An aortic thrombus may be detected by using transesophageal echocardiography after an embolic event. Clinical features are variable and may include cardiac and neurologic symptoms, such as the stroke. We report a case of a woman with an acute ischemic stroke, a myocardial infarction and a free floating aortic thrombus...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
