Abstract:
:Genetically controlled nitric oxide production is currently assessed mainly by the colorimetric determination of the plasma levels of nitrite/nitrates, specific end-products of NO, or by the magnitude of the vasorelaxation obtained with forearm occlusion venous plethysmography after infusion of stimulating (acetylcholine) or inhibiting (N-monomethyl-arginine) substances. NO levels decrease in the elderly compared to young people and more in men than in women. Many shear stresses (physical exercise, cold pressor test, mental test) increase NO production; in these circumstances NO inhibits platelet aggregation and endothelial adhesivity: among endogenous metabolic factors mainly LDL impairs endothelium dependent vasodilation through an altered synthesis of NO, whereas triglycerides seem to have no influence; oxidized LDL may stimulate NO-production to counteract its damaging effects on endothelial cells. The hypothesis whereby an early production of NO is followed by a drop due to a prolonged cell injury is still controversial. Lipid lowering agents (drugs, apheresis) improve endothelial function. Some endogenous vasoactive substances, (acetylcholine, adenosine, bradykinin, and arginine) stimulate NO production, whereas others, such as angiotensin II, histamine, aspirin, indomethacin have inhibitory effects. As regards drugs glyceriltrinitrate and isosorbide dinitrate, acting as NO donors, improve endothelial function; other drugs are current being studied in this sense.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Ferlito Skeywords:
subject
Has Abstractpub_date
2000-06-01 00:00:00pages
169-76issue
6eissn
0026-4725issn
1827-1618journal_volume
48pub_type
杂志文章,评审abstract::An aneurysms of a renal vein is very uncommon an entity and even more so when a visceral vein is affected. The venous aneurysms are generally asymptomatic and are detected either at post-mortem examination or by Echography, CT scan or MR investigation. Occasionally they become symptomatic because of rupture, thrombosi...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::Acute mesenteric ischemia is a severe complication after aortic reconstructive surgery for AAA repair. This ischemic event, due to a poor intestinal perfusion especially in ruptured AAA in consequence of the hypotension and the hypovolemic shock, shows different clinical manifestations such as delayed canalization, is...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract::This report describes a rare case of concurrent abdominal aortic aneurysm and bilateral renal ectopia. Preoperative work-up included intravenous pyelography and angiography to assess renal function, renal artery anatomy, and ureter position. Conventional surgery was performed without renal protection. No deterioration...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract::Some cases of coronary aneurysms studied echocardiographically in children suffering from Kawasaki's disease are reported. In the fourth case, bidimensional echocardiography highlighted a uniform dilatation of the right and left coronary proximal segments which had retreated at subsequent controls. In the third case, ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::The Authors describe a case of uniatrial univentricular heart with a right transposition and atresia of the aorta. This case forms part of an autoptic series of 74 congenital cardiopathies with defects of the septal system: monometameric (52 cases), polymetameric (22 cases), and limited (66 cases) or broad DIA, DIV or...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:AIM:We aimed to investigate the effects of verapamil and adenosine in an adjunct to intravenous tirofiban on management and prognosis of no-reflow phenomenon during primary percutaneous coronary intervention (PPCI) and to compare their efficacies on reversing of no-reflow phenomenon and short and midterm survival. MET...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:The purpose of this registry is to report the immediate and long-term safety and efficacy of the Biotronik Orsiro stent in an unselected population during everyday practice. METHODS:Between May 2012 and June 2013, 246 consecutive coronary angioplasty procedures were performed using at least one Orsiro drug-...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract::The universal definition of myocardial infarction has proved how important the role of biomarkers in the assessment of acute coronary syndrome (ACS) has become. As a result, management of patients with ACS today is more specific and personalized than ever, but there is still a lot of room for improvement. Unmet needs ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2011-06-01 00:00:00
abstract::We assessed the safety and efficacy of intravenous propafenone in the treatment of atrial fibrillation and flutter of recent onset (1-10 days). The drug was administered, at a dosage of 2 mg/kg, to 46 consecutive patients (with age variable from 35 to 86 years), 36 with atrial fibrillation, 10 with atrial flutter. The...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Drug-coated balloons (DCB) are widely used for several types of coronary artery disease, especially in-stent restenosis and de-novo small vessel disease. The role of correct lesion preparation is of paramount importance before DCB use. In the last years, the use of scoring balloons to achieve this goal has emerged as ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.19.05091-6
更新日期:2020-02-01 00:00:00
abstract:BACKGROUD:This study aimed to analyze the correlations between anterior wall motion velocity of ascending aorta measured by quantitative tissue velocity image (QTVI) technique and left ventricular geometry as well as left heart function to evaluate its value of clinical application. METHODS:One hundred ten hypertensio...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.17.04535-2
更新日期:2018-04-01 00:00:00
abstract:AIM:In-stent restenosis still affects 10-50% of long-term outcome after percutaneous coronary intervention (PCI). Large clinical trials have shown that sirolimus-eluting stents (SES) have reduced restenosis rate to 0-9% in lesions at low-moderate risk. The aim of this study was to evaluate long-term clinical and angiog...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract::Two hundred and one patients admitted to Coronary Care Unit with documented acute myocardial infarction, whose chest pain had occurred within 12 hours of hospital admission non thrombolised, were studied. The peak of creatine kinase (CK) was examined and compared between patients without previous manifestations of myo...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract::Despite advances in clinical interventions, drug therapy and preventative strategies for cardiovascular disease, heart disease remains the number one cause of death in the United States. A major cause of heart failure leading to death is myocardial ischemic disease. Terminal heart failure can be salvaged in some cases...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2010-02-01 00:00:00
abstract::The incidence of district (cardiac, cerebral, renal) and systemic vascular complications was studied in a population of 3992 hypertensive in-patients during the period from 1984 to 1988. The total number of male hypertensive patients was always higher (2355) than that of female hypertensive patients (1637). From the a...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract:: ...
journal_title:Minerva cardioangiologica
pub_type: 信件
doi:10.23736/S0026-4725.19.04916-8
更新日期:2019-10-01 00:00:00
abstract::Renal denervation is a novel catheter based approach that has been shown to effectively lower blood pressure in patients with resistant hypertension. Small studies have shown additional benefits in patients being treated for hypertension, such as improvements in insulin sensitivity, sleep apnoea and arrhythmias. More ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2013-06-01 00:00:00
abstract::After recalling that cardiovascular complications represent the most frequent cause of mortality and morbidity in hypertensive patients, the author describes the main mechanism responsible for increased plasma level concentrations of Angiotensin in this syndrome. He subsequently illustrates the effects of ACE-inhibito...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2001-10-01 00:00:00
abstract::Left main coronary artery (LMCA) disease has been reported in up to 10% of all patients with coronary artery disease (CAD) and in the majority of cases are associated with severe three-vessel CAD. Among patients with chronic coronary syndrome revascularization of significant LMCA disease improves prognosis, while ther...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05198-1
更新日期:2020-10-01 00:00:00
abstract::Cardiac tamponade may be caused by erosion of the right cardiac walls or of the intrapericardial superior vena cava in subjects with a central venous catheter. The underlying cause of this rare complication is direct parietal trauma by the catheter and endarterial damage produced by infused hyperosmolar solutions. Hig...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract::We report the clinical, echocardiographic and therapeutic aspect of one case of right cardiac migrant thromboembolus in pulmonary embolism. Medical therapy consisted of tissue plasminogen activator (rt-PA, 100 mg/3h). Progressive reduction of thromboembolus until its disappearance was observed by echo 2D after this th...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:It is known that resistance to activated protein C (APCR), often associated with a single point mutation (Arg506-->Gln) in the coagulation factor V gene (factor V Leiden), is the most frequent inherited abnormality of blood coagulation. It plays a key role as pathogenetic factor of venous thromboembolism, bu...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:AIM:To evaluate the relationship between body mass index (BMI), body fat distribution and some coronary heart disease risk factors like hyperlipidemia, hypertension and cigarette smoking. STUDY DESIGN:Cross-sectional. PLACE:Tiriolo, a little town close to Catanzaro, of prevalent rural economy. PARTICIPANTS:Volunteer...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract::Vasodilators represent one of the main steps for the medical treatment of pulmonary hypertension; the rationale for their use is the reversibility of the pulmonary vasoconstriction, to be tested with a correct pharmacological trial. In this report the authors consider the use of calcium-channel blockers, prostaglandin...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::Although drug-eluting stents (DES) have significantly reduced the rates of restenosis as compared to bare metal stents, late stent thrombosis remains a major drawback, especially for "off-label" use. Delayed arterial healing, characterized by persistent fibrin deposition and poor endothelialization, has been shown to ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-02-01 00:00:00
abstract::Chronic venous insufficiency and chronic venous ulcers represent an important medical problem, because of the high incidence and prevalence in the general population, and need to be considered as a lifelong degenerative condition, with socioeconomic consequences. Ulceration is a severe complication of the post-thrombo...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2015-06-01 00:00:00
abstract::Over the last years, endovascular intervention have become an important part of treatment in patients with congenital heart disease particularly for residual defects after surgery done in infancy. These transcatheter procedures can be described as dilatation of stenotic sites (angioplasty, endovascular stenting and va...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2007-10-01 00:00:00
abstract::The Impella left ventricular support system consists of two main components: a family of different ventricular support catheters with a microaxial pump to be placed across the aortic valve and a single external controller which is connected to activate and control the pump function. Four Impella left ventricular suppo...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.18.04703-5
更新日期:2018-10-01 00:00:00
abstract::Atrial fibrillation (AF) is the most common observed cardiac arrhythmia and is the most frequent condition associated with thromboembolic events in patients with or without mitral valve disease. The source of cardiac emboli is the left atrium, the left atrial appendage or, less frequently, the left ventricle. Emboli m...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2003-06-01 00:00:00
abstract::The metabolic abnormalities associated with diabetes mellitus result in macrovascular and microvascular complications in multiple organ systems; it is the cardiovascular impact that accounts for the greatest morbidity and mortality associated with this disease. Heart failure, both with reduced and preserved systolic f...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2004-12-01 00:00:00