Abstract：
:The study population was derived from 482 patients with breast cancer treated at the Department of Oncology, University Hospital Center Zagreb, between 1992 and 1999. The main purpose of our study was to evaluate differences in breast cancer characteristics and treatment in a population of women with breast cancer older than 65 years compared to younger women group (less than 65 years). We have analyzed disease parameters (stage of the disease, size of primary tumor, tumor differentiation grade and steroid receptor status) and parameters associated to treatment modalities (surgery, radiotherapy, hormonal therapy and chemotherapy) in both age groups. In older women, we found significantly higher rates of tumors grade 1 (p = 0.0049), tumors > 2 cm and tumors with a high steroid receptor status (p = 0.0013). Evaluation of treatment modalities showed that in older women a significantly higher proportion were treated with hormonal therapy (p < 0.001) compared to younger patients. In evaluation of clinical outcome after a median follow-up of 58 months, in older women the cumulative 5-year disease-free survival rate was 65%, while cumulative 5-year survival was 83%, which was not significantly different from the younger women (p > 0.005).
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Podolski P,Markulin Grgić L,Kukura V,Budisić Z,Santek Fkeywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
557-60issue
5eissn
0392-2936issn
2709-0086journal_volume
26pub_type
杂志文章abstract：BACKGROUND:Ovarian Brenner tumors are rare epithelial tumors that account for 1%-2% of all ovarian neoplasms. They can be subdivided into benign, borderline or proliferative, and malignant neoplasms. In the vast majority of cases, these lesions are benign. Tumors of borderline malignancy are less frequent and only abou...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:The aim of this survey was to compare the effect of letrozole with medroxyprogesterone acetate (MPA) in treatment of simple endometrial hyperplasia to preserve fertility in young women. MATERIALS AND METHODS:Forty-five patients referred to Shahid Sadoughi gynecology clinics from 2009 until 2011 who suffered...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2013-01-01 00:00:00
abstract：:Endometrial hyperplasia is a commonly seen disorder in daily gynecology practice. The clinical importance of this pathological entity is the underlying risk of carrying a concomittant genital cancer or risk of progression to endometrial carcinoma during the follow-up. Despite recent advances in non-invasive techniques...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：:Ovarian mucinous tumors stem from ovarian surface epithelium and are divided into benign, borderline and malignant. It is difficult to differentiate borderline and malignant mucinous tumors. Thirty-eight cases of ovarian mucinous tumors which were diagnosed at the Pathology Department of Dicle University Medical Facul...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The aim of this study was to describe the clinical features, methods of treatment and results of treatment among patients with primary invasive cancer. Twelve women in whom primary invasive cancer of the vagina was diagnosed between 1996 and 2001 were studied. The mean age of women with primary invasive vaginal cancer...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:A case of secretory (juvenile) carcinoma of the breast is reported in a 31-year-old woman. Secretory carcinoma in adults is rare, only twenty-seven cases previously reported. It is known to have a more favourable prognosis than the conventional ductal carcinoma. The most adequate treatment appears to be a simple maste...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：PURPOSE:To investigate whether the introduction of liquid-based cytology (LBC) in an urban setting decreases the diagnosis of glandular neoplasia (grade 6) and improves the positive predictive value (PPV) of cervical cytological screening. METHODS:A retrospective database review was conducted identifying women with ce...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Nongestational choriocarcinoma is very rare and carries a poor prognosis in female patients. In this report, the authors present a case of nongestational choriocarcinoma with brain metastasis in a female. A 58-year-old female with intermittent back pain was referred to a private hospital. On examination, a mediastinal...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:We have analyzed 37 cases of simultaneous appearance of carcinoma in the ovary and endometrium. This paper deals with the question of whether they should be considered stage III endometrial carcinomas, stage II ovarian carcinomas or independent primary tumors. The cases were grouped according to their histology as end...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Patients with invasive hydatidiform moles (IHM) have a good prognosis. Even if disease has spread, monocytostatic treatment might be sufficient if the diagnosis has been histologically confirmed. Established classifications divide gestational trophoblastic disease (GTD) including choriocarcinoma into cases w...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2005-01-01 00:00:00
abstract：:In a retrospective study, a total of 120 ovarian cancer patients were paired in terms of staging, grading, patent age, and operative and cytostatic therapy. Half of the patients underwent radioimmunoscintigraphy for diagnostic purposes. From the point of view of possible adjuvant immunological therapy, we investigated...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:It is difficult to find effective chemotherapy combination as third line treatment in epithelial ovarian cancer. In this paper the therapeutic response was evaluated of weekly administration of cis-platinum as third line chemotherapy, for a minimum of 6 cycles, on 8 patients, aged 41-72 years, with advanced ovarian ca...
journal_title：European journal of gynaecological oncology
pub_type： 临床试验,杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:2195 patients affected by endometrial carcinoma were treated at the Tbilisi and the St. Petersburg Oncological Institutes from 1968 to 1987. The incidence of different stages was respectively: I 78.8%; II 11.6%; III 9.0%; IV 0.4%. Adenocarcinoma was the histotype more frequently observed and the grade of differentiati...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,多中心研究
doi：
更新日期：1993-01-01 00:00:00
abstract：:The aim of this study is to draw attention to the possibility of the occurrence of a metastatic spread at the laparoscopic entrance site in patients suffering from a carcinoma of the ovary. This event has rarely been mentioned in medical literature before. A case is presented here in which a localized tumoral lesion a...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Bleomycin, Ifosfamide and Cisplatinum were combined in a 3 cycle regime of neoadjuvant chemotherapy given prior to radiotherapy in the treatment of 26 patients with late Stage (FIGO IIB-IIIB) cervical cancer. Seven patients were withdrawn for reasons of compliance and 1 patient due to toxicity. The response rate to ch...
journal_title：European journal of gynaecological oncology
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:We studied bcl-2 expression in patients with uterine cervical squamous cell carcinoma and correlated this phenomenon with survival. Immunohistochemical analysis with a monoclonal antibody specific for bcl-2 was used to detect the protein in tumor samples from 259 patients undergoing surgery for squamous cell carcinoma...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：AIM:The aim of this study was to determine the diagnostic value of thrombocytosis and high CA 125 levels in women with benign and malign adnexal masses. Thrombocytosis (platelet counts > 400 x 10(9)/l) has been identified as a poor prognostic factor in many cancers including certain gynecologic malignant tumors such as...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:1) To assess whether endometrial specimens obtained from removed uteri might show an increase in endometrial pathologies which had been previously diagnosed by hysteroscopy in postmenopausal breast cancer tamoxifen-treated patients. 2) To assess whether hysteroscopy is an efficient method of de...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:We report seven cases of intravenous leiomyomatosis. Growth beyond the uterus occurred in two of the seven cases in the broad ligament. One 21-year-old patient is one of the youngest reported cases in the literature. Five patients had total abdominal hysterectomy with removal of the adnexa and two patients underwent m...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Antibiotic therapy must be instituted promptly and on an empiric basis in neutropenic patients. We evaluated the efficacy of a combined antibiotic regimen of monobactam (aztreonam) and antipseudomonal penicillin (piperacillin) in treating neutropenic fever episodes in gynecologic-oncology patients receiving cisplatin-...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:The aim of this work was to examine three types of radical vaginal hysterectomy with different degrees of radicality, performed in order to reduce surgical complications and sequelae in different indications, and to test the feasibility of a new simple and quick technique for extraperitoneal pelvic lymphadene...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:Invasive squamous cell cancer of the vulva (ISCC) is a rare disease in young patients and in pregnant women. The purpose of this paper was to investigate this type of cancer in women less than 40 years old and to present three cases, one which was diagnosed in the third trimester of pregnancy. ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Class II HLA antigen expression was investigated in biopsy material from patients with preclinical cervical carcinoma. Class II molecules were determined immunohistochemically by MoAb against HLA-DR antigens. A significant reduction of class II positive cells was established in the tumor tissue compared to the normal ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:From May 1987 to May 1989 sixty one pre- and perimenopausal women with advanced or recurrent breast cancer entered in an open non comparative study. They were treated, as a first-line therapy, with goserelin (Zoladex ICI-118630) a long acting gonadotropin-releasing hormone (LH-RH)-analogue in a depot formulation. Fift...
journal_title：European journal of gynaecological oncology
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1991-01-01 00:00:00
abstract：:Ovarian tumors during the first two decades of life represent the most frequent tumors of the female genital tract at this age. Clinical and therapeutical particularities differentiate them from the same tumors of older women. During the period 1993-1997, 57 ovarian tumors were diagnosed and managed in the Divisions o...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to explore the expression of budding uninhibited by benzimidazoles-1 (Bub1) and mitotic arrest deficient-2 (Mad2) in endometrial carcinoma and its significance. MATERIALS AND METHODS:The expression of Bub 1 and Mad2 in 30 human normal endometrial tissues (group A), 30 complexly-hype...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：:Angiosarcomas rarely involve the female genital tract. There have only been sporadic case reports of angiosarcomas of the cervix, uterus, vagina, parametrium, broad ligament and pelvis, and only 11 well-documented case reports of primary ovarian angiosarcoma in the English language literature to date. We present a cas...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:We present a case of leiomyosarcoma of the right ovarian vein with MRI findings. The patient was a 52-year-old woman who had suffered from right flank pain for one week. Abdominal ultrasound and excretory urography revealed hydronephrosis of the right kidney. Ureteroscopy showed external compression at the right upper...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:According to recent epidemiological studies on ovarian cysts during pregnancy one out of 600 are, in most cases, benign neoformations. The most frequent histological type reported is mature cystic teratoma (50% of the cases), followed by functional cysts (13%), benign cystadenomas (20%) and ovarian cancer (0.6%). Most...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2005-01-01 00:00:00
abstract：:Despite its infrequency, pregnancy associated breast cancer implies multiple therapeutic dilemmas. Our patient, a 32-year-old Caucasian, gravida 2, para 2, was diagnosed with cancer of the left breast in the 19th week of gestation. Shortly after she underwent quadrantectomy plus axillary lymph node dissection. Chemoth...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
