Abstract：
:Class II HLA antigen expression was investigated in biopsy material from patients with preclinical cervical carcinoma. Class II molecules were determined immunohistochemically by MoAb against HLA-DR antigens. A significant reduction of class II positive cells was established in the tumor tissue compared to the normal cervical epithelium. A correlation between the tumor progression and the inhibition of the class II antigen expression was found.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Marinova-Mutafchieva L,Chakalova Gkeywords:
subject
Has Abstractpub_date
1992-01-01 00:00:00pages
494-7issue
6eissn
0392-2936issn
2709-0086journal_volume
13pub_type
杂志文章abstract：OBJECTIVE:To evaluate the relationship between the hematocrit (HCT), serum erythropoietin (EPO) and insulin-like growth factor-1 (ILGF-1) levels in breast cancer patients receiving non-nephrotoxic chemotherapy. METHODS:Seventeen patients with stage II breast cancer were included. All received 6 cycles of non-nephrotox...
journal_title：European journal of gynaecological oncology
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:A case of secretory (juvenile) carcinoma of the breast is reported in a 31-year-old woman. Secretory carcinoma in adults is rare, only twenty-seven cases previously reported. It is known to have a more favourable prognosis than the conventional ductal carcinoma. The most adequate treatment appears to be a simple maste...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:In a series of 151 patients diagnosed with cervical carcinoma the prognostic importance of temperature elevation, anaemia and smoking during radiotherapy was evaluated. Tumor necrosis and infection at the start of therapy were also analysed. A febrile reaction during irradiation seems to be an ominous sign with regard...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:For both cervical cancer (UCC) and endometrial cancer (EMC) there are no effective prognostic markers. In this study, we evaluated HIG2 protein expression in 332 uterine cancers (186 UCCs and 146 EMCs) and examined the relationship between HIG2 protein expression and clinical factors, including prognosis. Totally, HIG...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:Genotyping of UGTI1Al could be useful for prediction of severe toxicities for patients treated with irinotecan; however, genotype-based recommended dose (RD) has not been established. The aim of the present study was to determine the RD of irinotecan in combination with cisplatin (CPT-P) for individuals wi...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:With the three modalities of cancer treatment, surgery, radio- and chemo-therapy, even when applied in optimal conditions, over 50% of patients remain incurable because of metastatic disease. Hence the importance of preventive methods of approach to cancer. Host human tumors arise in renewing cell populations, while o...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Endometrial adenocarcinoma is the most common malignant neoplasm of the female genital tract and, despite its relative frequency, the molecular events that contribute to the development and progression of the lesion remain poorly understood. The normal human endometrium is characterized by hormone-dependent variations...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To further study the clinicopathologic and immunohistochemical features of ovarian granulosa cell tumors (GCTs). METHODS:We retrospectively studied all cases of GCTs diagnosed in our laboratory over the last 10-year period. Immunohistochemistry for inhibin, vimentin, cytokeratin, Ki-67 and p53 was performed on...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:To estimate the prognostic value of pelvic-node removal on survival of patients affected by endometrial carcinoma at presurgical FIGO Stage I. METHODS:A retrospective analysis was performed on a total of 111 patients recruited from 1990 to 1996 at the S. Carlo di Nancy Hospital. Thirty-nine (35%) of them un...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to explore the expression of budding uninhibited by benzimidazoles-1 (Bub1) and mitotic arrest deficient-2 (Mad2) in endometrial carcinoma and its significance. MATERIALS AND METHODS:The expression of Bub 1 and Mad2 in 30 human normal endometrial tissues (group A), 30 complexly-hype...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：:The concentration of c-erbB-2 oncoprotein (HER-2/neu) was examined in the membrane fraction of 196 breast cancer and 39 benign breast specimens using a recently introduced ELISA-assay. The results were compared with established clinical and laboratory prognostic factors, 19% of all breast cancer specimens showed a c-e...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:A 15 year retrospective study of chemotherapy response to multiple regimens employed in 78 evaluable patients with advanced uterine sarcoma was performed. Single agent activity was noted with doxorubicin, methotrexate, and cisplatin (5-11% response rate). Effective multigent regimens included cyclophosphamide, vincris...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:To assess the impact of surgical staging on treatment modification and outcome in endometrial carcinoma (EC) patients. METHODS:Two groups of histologically confirmed clinical Stage I and II EC patients, diagnosed during two time periods (1976-1984 and 1985-1991), were retrospectively compared. Sixty-five pat...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Neoadjuvant chemotherapy in gynecological cancers is an approach that is shown to have positive effects on survival. It increases the rate of resectability in ovarian and cervical cancers and thus contributes to survival. However, there are studies reporting that despite increasing operability, the approach does not m...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:Invasive squamous cell cancer of the vulva (ISCC) is a rare disease in young patients and in pregnant women. The purpose of this paper was to investigate this type of cancer in women less than 40 years old and to present three cases, one which was diagnosed in the third trimester of pregnancy. ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Infection with high-risk human papillomavirus (hr-HPV) 16, 18, and 45 causes 94% of cervical carcinoma. In the present screening center the authors perform the hr-HPV test followed by Pap test to women aged 35-64 years if they result hr-HPV+. The authors' aimed to provide data regarding the genotyping test and eventua...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Only a few renin-producing ovarian tumors have been reported, and most such ovarian tumors have been sex cord/stromal tumors. Renin-producing ovarian epithelial tumors are quite rare. CASE:A 46-year-old woman presented with hypertension and hypokalemia. Examinations of the patient revealed elevated plasma r...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:Amelanotic malignant melanoma of the vulva is extremely rare. The authors describe here a case of amelanotic malignant melanoma of the vulva, occurring in a 71-year-old woman without any clinical symptoms. The woman had a small nodular lesion in the left labia majora. Local excision was performed. Histological examina...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2016-08-01 00:00:00
abstract：:402 radical hysterectomies (17 ultraradical) were performed with lymphadenectomy. Positive metastatic nodes (N+) rate was 23.6% with an arithmetic mean of 22 excised lymph nodes. Single N+ belonged mostly to the obturatory group, double N+ to obturatory and external iliac groups, while multiple N+ (24 cases) had no pa...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Endometrial hyperplasia is a commonly seen disorder in daily gynecology practice. The clinical importance of this pathological entity is the underlying risk of carrying a concomittant genital cancer or risk of progression to endometrial carcinoma during the follow-up. Despite recent advances in non-invasive techniques...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to examine the prognostic significance of vascular endothelial growth factor (VEGF) in epithelial ovarian cancer (EOC). METHODS:Surgical specimens of 105 patients with primary EOC FIGO Stages 1 to 4, who underwent surgical staging, were investigated. Expression of VEGF was evaluate...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:The aim of this survey was to compare the effect of letrozole with medroxyprogesterone acetate (MPA) in treatment of simple endometrial hyperplasia to preserve fertility in young women. MATERIALS AND METHODS:Forty-five patients referred to Shahid Sadoughi gynecology clinics from 2009 until 2011 who suffered...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2013-01-01 00:00:00
abstract：:The elderly population is increasing in number. Aggressive therapeutic intervention in this patient group may not always be possible because of age, the presence of co-morbidity, and poor functional status. Hence, individualized management of cervix cancer (CC) in the elderly is often practiced. Because of the precedi...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:We aimed to investigate the utility and efficacy of the Keyes skin biopsy instrument for cervical biopsy procedures. MATERIAL AND METHODS:A prospective clinical trial was conducted on 50 women with cervical lesions. Colposcopy-guided cervical biopsies were collected using a Keyes biopsy punch and a Kevorkian...
journal_title：European journal of gynaecological oncology
pub_type： 临床试验,杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:To determine the effect of imatinib on progression-free survival in patients with epithelial ovarian cancer in second or greater complete clinical remission (CCR). METHODS:35 patients were enrolled between 10/2002 and 1/2005. Eligible patients received imatinib at 400 mg daily orally. RESULTS...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:Some Japanese institutes have been performing a population screening program for cervix cancer involving the simultaneous use of Pap smear and colposcopy. This program may be a good model for evaluating the efficacy of Pap smears and colposcopy. METHODS & MATERIALS:The subjects included 2,000 women who under...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：PURPOSE:To further study the clinicopathological features of synchronous ovarian and endometrial carcinomas. METHODS:We retrospectively studied all cases of synchronous ovarian and endometrial carcinomas diagnosed in our laboratory over the last 15-year period. The pathological findings were correlated with the clinic...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:The authors aimed to confirm the depth of six mm in order to achieve an optimal eradication of the lesion. MATERIALS AND METHODS:This is a retrospective observational study of 94 cervical surgical pieces from women aged 17 to 22 years with a cyto-colpo-histopathological diagnosis of high-grade squamous cerv...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:The aim of this study is to draw attention to the possibility of the occurrence of a metastatic spread at the laparoscopic entrance site in patients suffering from a carcinoma of the ovary. This event has rarely been mentioned in medical literature before. A case is presented here in which a localized tumoral lesion a...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Sixty four patients with epithelial ovarian cancer underwent second-look laparotomy. Influencing factors on the outcome of the second-look laparotomy were analysed. Both grade and stage appeared to have an effect on the outcome of the procedure. However, this effect appeared to be dependent on the amount of residual d...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
