Abstract：
:We discuss 19 cases of infection due to Cryptococcus neoformans diagnosed in 438 AIDS patients admitted to our center (4%). Fourteen of them showed meningitis confirmed by culture of C. neoformans in CSF. Clinical features were rather unspecific and disorders in CSF parameters were non striking. The diagnostic techniques performed with best results were culture of C. neoformans and antigen determination, especially in serum. Survival probability at one year was 75%. Treatment response was good. Treatment with fluocytosine did not seem to provide additional benefits versus amphotericin alone, neither in respect to clinical evolution nor regarding survival probability at one year. Fluconazole has shown effectiveness in maintenance therapy, being not be possible to evaluate it as an acute phase therapy because the low number of cases in which it was studied. It is advisable to follow a suppressive treatment, having found a 10% relapse rate in patients following therapy and a 50% in those who interrupted it.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Gazapo Carretero E,García Aguado C,Adrados de Llano M,Martínez Blanco ML,Verdejo Ortes J,González Lahoz JMkeywords:
subject
Has Abstractpub_date
1992-05-01 00:00:00pages
450-4issue
9eissn
0014-2565issn
1578-1860journal_volume
190pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVES:The Computerized Registry of Patients with Venous Thromboembolism (RIETE) is a prospective registry that consecutively includes patients diagnosed with venous thromboembolism. We compared the clinical presentation and response to anticoagulant treatment in patients with idiopathic venous throm...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2014.05.017
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Despite a steady decrease in its incidence, pneumonia caused by Pneumocystis carinii (PCP) are still diagnosed, and they occur frequently in patients unaware of being infected with the human immunodeficiency virus (HIV). Since it is a disease with a high mortality risk, its early diagnosis and therapy would ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71100-4
更新日期：2002-08-01 00:00:00
abstract：:Our objective has been to elaborate an updated Clinical Guide of the Spanish Society of Internal Medicine (SEMI) for the prevention and treatment of glucocorticoids-induced osteoporosis (GIO), identifying and measuring the grade of evidence that supports the given recommendations. For this, we reviewed studies perform...
journal_title：Revista clinica espanola
pub_type： 杂志文章,实务指引
doi：10.1157/13115006
更新日期：2008-01-01 00:00:00
abstract：:Malign small cell tumors in the thoracopulmonary region is a tumor of neuroectodermic origins with polymorphous and infrequent presentation. It is mostly found among young people, developing an aggressive and severe course. It is a small cell tumor involving small quantities of cytoplasm without glucogen, round or ova...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:The limitation of the therapeutic effort (LTE) consists in not applying extraordinary or disproportionate measures for therapeutic purposes that are proposed for a patient with poor life prognosis and/or poor quality of life. There are two types. The first is to not initiate certain measures or to withdraw them when t...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2011.04.016
更新日期：2012-03-01 00:00:00
abstract：INTRODUCTION:The use of bone marrow transplantation (BMT) in leukemia treatment is associated with high early morbid-mortality rates. Therefore, to identify morbid-mortality risk factors in this setting can be useful to improve therapeutic ratio. METHODS:We studied 15 variables in 46 patients with chronic myeloid leuk...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:Cyclophosphamide is used both in the treatment of malignant and non-malignant diseases. Urinary neoplasms secondary to its use have been described. We discuss the case of a patient with panarteritis nodosa treated with cyclophosphamide during 63 months, with a total dose of 210 grams, and that showed a bladder neoplas...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：INTRODUCTION:In decompensated heart failure (HF), both acute kidney injury (AKI) and high Galectina-3 (Gal-3) levels have been associated with poorer outcomes. Plasma Gal-3 levels are affected by renal function; however, the potential role of Gal-3 as a predictor of AKI has not been established. METHODS:We measured Ga...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2018.10.004
更新日期：2019-01-01 00:00:00
abstract：:Although the number of elderly needing health care is increasing in Spain, geriatric patients do not receive enough attention or support when compared to that given in other countries. When the elderly get sick they present peculiar and special problems which should be attended following their needs. Because in hospit...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Coeliac disease is the most frequent malabsortive syndrome in daily practice. However, its true prevalence is not exactly known. The symptoms vary from patient to patient, ranging from the classic presentation with diarrhea, weight loss and fatigue to oligosymptomatic forms, being the latter more common in adults. We ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The editors of Revista Clínica Española (Rev Clin Esp) inform on their editorial activity during the last 12 months (November 2010 to October 2011): (a) Objectives and attainments during 2011, (b) editorial activity, and (c) objectives for 2012. In 2011 we have updated the editorial algorithm (revision by the responsi...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2011.11.004
更新日期：2012-01-01 00:00:00
abstract：:Antibodies (type IgG) against the A 60 antigen (Mycobacterium bovis, BCG) and an antigen of Mycobacterium tuberculosis were studied by ELISA in 79 patients with not tuberculous disease: 16 lung carcinoma, 16 hepatic cirrhosis and 47 patients with pulmonary disease. 59.5% and 50.6% of the patients showed antibodies aga...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:The polyacrylamide gel electrophoresis of spinal fluid from 488 patients suffering neurological diseases and from a control group are reviewed. One hundred and eleven cases (22.7%) showed oligoclonal bands (OB). The highest percentage of OB appeared in the group of patients with definite multiple sclerosis (84%), foll...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:The purpose of this study was to review the epidemiological aspects and the characteristics of the thyroid disfunction produced by amiodarone in Catalonia, an area with type I endemic goiter. For this purpose, three groups of patients have been studied: 1) 102 patients with prolonged amiodarone treatment, out of whom ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：OBJECTIVE:To determine the bacterial etiology of bacteremic episodes recorded at our hospital during 1995 and their antimicrobial susceptibility patterns. METHODS:The microbiological records of all bacteremic episodes detected at our hospital from January to December 1995 were analysed. The susceptibility patterns of ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：:Cystic neoplasms of the pancreas make up a group of uncommon tumors. Their relevance lies upon their favorable prognosis after resection and the fact of being commonly mistaken with pseudocysts. Based on five patients treated at our hospital in the last few years we make an update review of the literature on these tum...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1999-05-01 00:00:00
abstract：:The contributions of Santiago Ramon y Cajal to Modern medicine are innumerable. This large scientist and humanist, a man ahead of his time, spoke for the first time such concepts as angiogenesis, which represents one of the most innovative fields for oncology today, in addition to conducting experimental research on t...
journal_title：Revista clinica espanola
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0014-2565(08)76037-5
更新日期：2008-12-01 00:00:00
abstract：INTRODUCTION:The day hospital is an alternative to hospitalization. This alternative improves accessibility and comfort of the patients, and avoids hospitalizations. Nevertheless, the efficacy of the polyvalent medical day hospital in avoiding hospitalizations has not been evaluated. OBJECTIVE:To analyze hospital stay...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2011.08.003
更新日期：2012-02-01 00:00:00
abstract：:We have had the chance to follow three patients with thoracic actinomycosis in a relatively short period of time (18 months). They were three male patients, with chronic dental infections. The illness appeared as toxic syndrome and fever. In all three cases diagnosis was made through samples obtained through fibroptic...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
abstract：:Patobiographic data of four brilliant painters who lived in three different centuries (Goya [XVIII], Fortuny and Van Gogh [XIX] and Portinari [XX]), were examined in search for a suspected lead poisoning. It is concluded that Goya's disease and deafness was probably caused by lead poisoning. Fortuny's death was probab...
journal_title：Revista clinica espanola
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0014-2565(06)72707-2
更新日期：2006-01-01 00:00:00
abstract：:Two cases are reported of women aged 18 and 36 years respectively who developed a typical picture of hyperthyroidism by Graves Basedow disease (primary hyperthyroidism, diffuse goiter with increased uptake, positive stimulating thyroid antibodies, exophthalmos). These women had taken drugs for obesity which were prepa...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：BACKGROUND:In recent years, there has been an increase of drugs poisoning cases seen in the Emergency Department. This study has aimed to evaluate the characteristics of these cases in the Ramón and Cajal Hospital in Madrid. MATERIALS AND METHODS:A descriptive analysis about the drug poisonings diagnosed in 2004 was p...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13127603
更新日期：2008-10-01 00:00:00
abstract：:In an open-controlled trial--oral washes (20 patients) versus test (19 patients)--, we have studied the effects of AM3 (a new oral BRM) on clinical evolution of the recurrent stomatitis (RAS) syndrome. The results obtained at 6th month showed significant decreases on ulcer numbers (p less than 0.001) as well as in the...
journal_title：Revista clinica espanola
pub_type： 临床试验,杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:Cancer of unknown primary site (CUPS) is a heterogeneous entity defined by the presence of a histologically-proven metastatic neoplasm, in which the original tumor cannot be identified after a targeted study. The current guidelines for CUPS focus is not based on the search for the primary neoplasm but rather on the id...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(09)71820-x
更新日期：2009-07-01 00:00:00
abstract：:We discuss the case of a 22-year-old female, carrying of antibodies to against human immunodeficiency virus (HIV), who developed several tumors on different bone localizations, which corresponded to plurifocal bone tuberculosis. We reviewed multifocal bone tuberculosis reports in the literature. The exceptionally of t...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1992-06-01 00:00:00
abstract：OBJECTIVE:To determine the primary drug resistance (PDR) of Mycobacterium tuberculosis in ten hospitals in the Castile-León Community for a five-year period (1991-1995), in a sanitary area with almost two millions of inhabitants. MATERIAL AND METHODS:The sensitivity of 825 strains of Mycobacterium tuberculosis to anti...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Burnout is a psychosocial syndrome caused by stressful working conditions and affects 30-60% of medical personnel. The aim of this study was to assess the burnout rate of Spanish internists and the factors related to its onset. MATERIAL AND METHODS:We conducted a survey of work conditions fol...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2019.10.009
更新日期：2020-01-01 00:00:00
abstract：:Polymicrobial endocarditis (PE) is uncommon, whether in series of cases of polymicrobial bacteriemia or of endocarditis. Among the 201 cases of infective endocarditis seen between 1986 and 1995 by an infectious diseases service, 12 patients had PE (6%). Nine were males, mean age was 28 years and ten were active intrav...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：OBJECTIVE:Although the genetic component in colorectal carcinoma (CRC) is well established, some environmental factors, mainly dietary, can favor its development. The objective of this study is to evaluate the relationship between daily consumption of specific food groups and development of CRC. METHODS:We carried out...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13063526
更新日期：2004-07-01 00:00:00
abstract：:Non insulin antidiabetic drugs are widely used in patients with type 2 diabetes. However, the drugs' effect in terms of reducing cardiovascular risk has been the subject of controversy. In 2008, based on the evidence of cardiovascular risk resulting from the use of a number of non insulin antidiabetic drugs, the US Fo...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.02.007
更新日期：2017-11-01 00:00:00
