当前位置： SCI文献检索 > HEART RHYTHM期刊下所有文献 > Ciprofloxacin-induced acquired long QT syndrome.

Ciprofloxacin-induced acquired long QT syndrome.

Abstract：

:Quinolone antibiotics have potentially serious proarrhythmic effects. The effects on intracardiac potassium channels result in QT interval prolongation, leading to torsades de pointes. Evidence suggests fluoroquinolones cause QT-mediated proarrhythmia, and weak evidence links ciprofloxacin with QT-mediated arrhythmias. Ciprofloxacin may be given to select patients because the agent is believed to be safer than other drugs in its class. We report two cases of unexplained cardiac arrest temporally related to ciprofloxacin administration. Two female patients (ages 44 and 67 years) developed marked QTc prolongation (QTc 590 and 680 ms) within 24 hours of ciprofloxacin administration, with recurrent syncope and documented torsades de pointes requiring defibrillation. The patients previously were stable with sotalol and amiodarone therapy for supraventricular arrhythmia without obvious QTc prolongation prior to ciprofloxacin therapy. Marked QTc prolongation and subsequent proarrhythmia became a clinical concern only after initiation of ciprofloxacin. In both cases, the QTc normalized after cessation of ciprofloxacin. Ciprofloxacin may cause QTc prolongation and rarely torsades de pointes. This effect is of particular concern in patients with predisposing factors, such as concomitant medications or underlying heart disease reflecting decreased repolarization reserve.

journal_name

Heart Rhythm

journal_title

Heart rhythm

authors

Prabhakar M,Krahn AD

doi

10.1016/j.hrthm.2004.06.020

keywords:

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

624-6

issue

5

eissn

1547-5271

issn

1556-3871

pii

S1547-5271(04)00417-5

journal_volume

1

pub_type

杂志文章

相关文献

HEART RHYTHM文献大全
  • Double SCN5A mutation underlying asymptomatic Brugada syndrome.

    abstract：OBJECTIVES:The purpose of this study was to identify risk markers in patients with Brugada syndrome. BACKGROUND:Patients with Brugada syndrome who experience syncope or aborted sudden death are at high risk for recurrent lethal arrhythmias. The prognosis and therapeutic approaches in asymptomatic individuals with a Br...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2004.11.022

    authors： Yokoi H,Makita N,Sasaki K,Takagi Y,Okumura Y,Nishino T,Makiyama T,Kitabatake A,Horie M,Watanabe I,Tsutsui H

    更新日期：2005-03-01 00:00:00

  • Caring for the pregnant woman with an inherited arrhythmia syndrome.

    abstract：:Pregnancy is a period of increased cardiovascular risk in a woman's life. In the setting of an inherited arrhythmia syndrome (IAS), cardiologists and obstetricians may be unfamiliar with cardiovascular optimization and risk stratification in pregnancy. Historically, there were little data addressing the safety of preg...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2019.08.004

    authors： Roston TM,van der Werf C,Cheung CC,Grewal J,Davies B,Wilde AAM,Krahn AD

    更新日期：2020-02-01 00:00:00

  • Moderate alcohol consumption is associated with atrial electrical and structural changes: Insights from high-density left atrial electroanatomic mapping.

    abstract：BACKGROUND:Regular alcohol intake is an important modifiable risk factor associated with atrial fibrillation (AF) and left atrial (LA) dilation. OBJECTIVE:The purpose of this study was to determine the impact of different degrees of alcohol consumption on atrial remodeling using high-density electroanatomic mapping. ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2018.10.041

    authors： Voskoboinik A,Wong G,Lee G,Nalliah C,Hawson J,Prabhu S,Sugumar H,Ling LH,McLellan A,Morton J,Kalman JM,Kistler PM

    更新日期：2019-02-01 00:00:00

  • Vagal activity modulates spontaneous augmentation of J-wave elevation in patients with idiopathic ventricular fibrillation.

    abstract：BACKGROUND:Although J-wave elevation in the inferolateral leads could be related to idiopathic ventricular fibrillation (IVF), little is known about the pathophysiologic characteristics of J-wave elevation in patients with IVF. OBJECTIVE:This study aimed to determine the relationship between augmentation of J-wave ele...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2011.09.055

    authors： Mizumaki K,Nishida K,Iwamoto J,Nakatani Y,Yamaguchi Y,Sakamoto T,Tsuneda T,Kataoka N,Inoue H

    更新日期：2012-02-01 00:00:00

  • Risk of atrial fibrillation as a function of the electrocardiographic PR interval: results from the Copenhagen ECG Study.

    abstract：BACKGROUND:Prolongation of the PR interval has been associated with an increased risk of incident atrial fibrillation (AF). OBJECTIVE:To determine if there was a nonlinear relation between PR interval duration and the risk of AF. METHODS:We included 288,181 individuals, corresponding to one third of the population in...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2013.04.012

    authors： Nielsen JB,Pietersen A,Graff C,Lind B,Struijk JJ,Olesen MS,Haunsø S,Gerds TA,Ellinor PT,Køber L,Svendsen JH,Holst AG

    更新日期：2013-09-01 00:00:00

  • Gender differences in patients with Brugada syndrome and arrhythmic events: Data from a survey on arrhythmic events in 678 patients.

    abstract：BACKGROUND:There is limited information on gender differences in patients with Brugada syndrome (BrS) who experienced arrhythmic events (AEs). OBJECTIVE:The purpose of this study was to compare clinical, electrocardiographic (ECG), electrophysiological, and genetic characteristics between males and females in patients...

    journal_title：Heart rhythm

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.hrthm.2018.06.019

    authors： Milman A,Gourraud JB,Andorin A,Postema PG,Sacher F,Mabo P,Conte G,Giustetto C,Sarquella-Brugada G,Hochstadt A,Kim SH,Juang JJM,Maeda S,Takahashi Y,Kamakura T,Aiba T,Leshem E,Michowitz Y,Rahkovich M,Mizusawa Y,Arbe

    更新日期：2018-10-01 00:00:00

  • Bidirectional ventricular tachycardia: ping pong in the His-Purkinje system.

    abstract：BACKGROUND:Bidirectional ventricular tachycardia (BVT), which is characterized by an alternating beat-to-beat ECG QRS axis, is a rare but intriguing arrhythmia associated with digitalis toxicity, familial catecholaminergic polymorphic ventricular tachycardia (CPVT), and several other conditions that predispose cardiac ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2010.11.038

    authors： Baher AA,Uy M,Xie F,Garfinkel A,Qu Z,Weiss JN

    更新日期：2011-04-01 00:00:00

  • High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia.

    abstract：BACKGROUND:Atrioventricular nodal reentrant tachycardia (AVNRT) may coexist with Brugada syndrome (BrS). OBJECTIVES:The present study was designed to determine the prevalence of drug-induced type 1 Brugada ECG pattern (concealed BrS) in patients presenting with clinical spontaneous AVNRT and to investigate their elect...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2015.03.015

    authors： Hasdemir C,Payzin S,Kocabas U,Sahin H,Yildirim N,Alp A,Aydin M,Pfeiffer R,Burashnikov E,Wu Y,Antzelevitch C

    更新日期：2015-07-01 00:00:00

  • Catheter ablation of ventricular tachycardia: skill versus technology.

    abstract：:Despite the increasing number of sophisticated, computerized tools available to the practicing electrophysiologist for facilitating catheter ablation of ventricular tachycardia, the procedure is often quite challenging. Use of these tools needs to be kept in perspective, subservient to the judgment of the physician. T...

    journal_title：Heart rhythm

    pub_type： 杂志文章,评审

    doi：10.1016/j.hrthm.2009.02.014

    authors： Miller JM,Scherschel JA

    更新日期：2009-08-01 00:00:00

  • Characterization of the molecular phenotype of two arrhythmogenic right ventricular cardiomyopathy (ARVC)-related plakophilin-2 (PKP2) mutations.

    abstract：BACKGROUND:Arrhythmogenic right ventricular cardiomyopathy (ARVC) has been linked to mutations in desmosomal proteins, including plakophilin-2 (PKP2). Little is known about the changes in cellular function and structure that follow expression of ARVC-relevant PKP2 mutations. OBJECTIVE:The purpose of this study was to ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2008.09.009

    authors： Joshi-Mukherjee R,Coombs W,Musa H,Oxford E,Taffet S,Delmar M

    更新日期：2008-12-01 00:00:00

  • Mitochondrial oxidative stress during cardiac lipid overload causes intracellular calcium leak and arrhythmia.

    abstract：BACKGROUND:Diabetes and obesity are associated with an increased risk of arrhythmia and sudden cardiac death. Abnormal lipid accumulation is observed in cardiomyocytes of obese and diabetic patients, which may contribute to arrhythmia, but the mechanisms are poorly understood. A transgenic mouse model of cardiac lipid ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2016.05.002

    authors： Joseph LC,Subramanyam P,Radlicz C,Trent CM,Iyer V,Colecraft HM,Morrow JP

    更新日期：2016-08-01 00:00:00

  • Cloning, functional characterization, and remodeling of K2P3.1 (TASK-1) potassium channels in a porcine model of atrial fibrillation and heart failure.

    abstract：BACKGROUND:Effective treatment of atrial fibrillation (AF) remains an unmet need. Human K2P3.1 (TASK-1) K(+) channels display atrial-specific expression and may serve as novel antiarrhythmic targets. In rodents, inhibition of K2P3.1 causes prolongation of action potentials and QT intervals. We used a porcine model to f...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2014.06.020

    authors： Schmidt C,Wiedmann F,Langer C,Tristram F,Anand P,Wenzel W,Lugenbiel P,Schweizer PA,Katus HA,Thomas D

    更新日期：2014-10-01 00:00:00

  • Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation.

    abstract：BACKGROUND:Arterial hypertension (HT) contributes to progression of atrial fibrillation (AF) via unknown mechanisms. OBJECTIVE:We aimed to characterize electrical and structural changes accounting for increased AF stability in a large animal model of rapid atrial pacing (RAP)-induced AF combined with desoxycorticoster...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2018.05.016

    authors： Manninger M,Zweiker D,van Hunnik A,Alogna A,Prassl AJ,Schipke J,Zeemering S,Zirngast B,Schönleitner P,Schwarzl M,Herbst V,Thon-Gutschi E,Huber S,Rohrer U,Ebner J,Brussee H,Pieske BM,Heinzel FR,Verheule S,Antoons G,

    更新日期：2018-09-01 00:00:00

  • Incidence and predictors of atrial fibrillation progression: A systematic review and meta-analysis.

    abstract：BACKGROUND:More sustained forms of atrial fibrillation (AF) are less amenable to treatment and associated with worse outcomes, but the incidence and predictors of AF progression are not well defined. OBJECTIVE:The purpose of this study was to perform a systematic review and meta-analysis assessing the incidence and pr...

    journal_title：Heart rhythm

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.hrthm.2018.10.022

    authors： Blum S,Meyre P,Aeschbacher S,Berger S,Auberson C,Briel M,Osswald S,Conen D

    更新日期：2019-04-01 00:00:00

  • Probability and magnitude of response to cardiac resynchronization therapy according to QRS duration and gender in nonischemic cardiomyopathy and LBBB.

    abstract：BACKGROUND:QRS morphology and QRS duration (QRSd) determine cardiac resynchronization therapy (CRT) candidate selection but criteria require refinement. OBJECTIVE:To assess CRT effect according to QRSd, treated by dichotomization vs a continuous function, and modulation by gender. METHODS:Patients selected were those...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2014.04.001

    authors： Varma N,Manne M,Nguyen D,He J,Niebauer M,Tchou P

    更新日期：2014-07-01 00:00:00

  • MicroRNA-135a regulates sodium-calcium exchanger gene expression and cardiac electrical activity.

    abstract：BACKGROUND:Complete atrioventricular block (CAVB) causes arrhythmogenic remodeling and increases the risk of torsades de pointes arrhythmias. MicroRNAs (miRNAs) are key regulators of gene expression that contribute to cardiac remodeling. OBJECTIVE:The purpose of this study was to assess miRNA changes after CAVB and id...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2017.01.045

    authors： Duong E,Xiao J,Qi XY,Nattel S

    更新日期：2017-05-01 00:00:00

  • Novel utility of cryoablation for ventricular arrhythmias arising from the left aortic cusp near the left main coronary artery: a case series.

    abstract：BACKGROUND:Ablation of ventricular tachycardia and premature ventricular contraction arising at the aortic root has been described. The use of radiofrequency ablation energy has been associated with life-threatening collateral damage. The use of cryoablation as a safer alternative energy source at the aortic root has n...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2013.10.008

    authors： McDonnell K,Rhee E,Srivathsan K,Su W

    更新日期：2014-01-01 00:00:00

  • Electrophysiologic delineation of the tachycardia circuit in the slow-slow form of atrioventricular nodal reentrant tachycardia.

    abstract：BACKGROUND:Little is known about the exact boundaries of the reentrant circuit in the slow-slow form of atrioventricular nodal reentrant tachycardia (AVNRT). OBJECTIVE:The purpose of this study was to examine the tachycardia circuit in the slow-slow form of AVNRT. METHODS:Single extrastimuli were delivered during the...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2007.02.010

    authors： Yamabe H,Tanaka Y,Morihisa K,Uemura T,Kawano H,Nagayoshi Y,Kojima S,Ogawa H

    更新日期：2007-06-01 00:00:00

  • Outcomes of catheter ablation of anteroseptal and midseptal accessory pathways in pediatric patients.

    abstract：BACKGROUND:Outcomes for catheter ablation of accessory pathways in pediatric patients have steadily improved, with the exception of pathways located in the anteroseptal (AS) and midseptal (MS) regions, where success is limited by the close proximity of normal atrioventricular conduction. OBJECTIVE:The purpose of this ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2019.12.008

    authors： Kovach JR,Mah DY,Abrams DJ,Alexander ME,Cecchin F,Triedman JK,Walsh EP

    更新日期：2020-05-01 00:00:00

  • Electrophysiologic substrate and intraventricular left ventricular dyssynchrony in nonischemic heart failure patients undergoing cardiac resynchronization therapy.

    abstract：BACKGROUND:Electrocardiographic imaging (ECGI) is a method for noninvasive epicardial electrophysiologic mapping. ECGI previously has been used to characterize the electrophysiologic substrate and electrical synchrony in a very heterogeneous group of patients with varying degrees of coronary disease and ischemic cardio...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2011.01.017

    authors： Ghosh S,Silva JN,Canham RM,Bowman TM,Zhang J,Rhee EK,Woodard PK,Rudy Y

    更新日期：2011-05-01 00:00:00

  • QRS narrowing is associated with reverse remodeling in patients with chronic right ventricular pacing upgraded to cardiac resynchronization therapy.

    abstract：BACKGROUND:Patients with chronic right ventricular pacing (RVP) upgraded to cardiac resynchronization therapy (CRT) have been excluded from the majority of clinical trials of CRT. Little is known about the predictors of response in this population. We hypothesized that reversal of RVP-induced electrical dyssynchrony (i...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2012.09.018

    authors： Rickard J,Cheng A,Spragg D,Cantillon D,Chung MK,Tang WH,Wilkoff BL,Varma N

    更新日期：2013-01-01 00:00:00

  • Common wearable devices demonstrate variable accuracy in measuring heart rate during supraventricular tachycardia.

    abstract：BACKGROUND:Wearable devices are used as a noninvasive method of monitoring health. The accuracy of wearables for heart rate (HR) monitoring has been extensively studied in sinus rhythm, but evidence for tachyarrhythmias, particularly supraventricular tachycardia (SVT), is sparse. OBJECTIVE:The purpose of this study wa...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2020.02.018

    authors： Sequeira N,D'Souza D,Angaran P,Aves T,Dorian P

    更新日期：2020-05-01 00:00:00

  • Pathophysiologic basis of autonomic ganglionated plexus ablation in patients with atrial fibrillation.

    abstract：:The intrinsic cardiac autonomic nervous system (ganglionated plexuses [GP]) plays a significant role in the initiation and maintenance of atrial fibrillation (AF) in both experimental models and AF patients. Left atrial GP, located in epicardial fat pads and the ligament of Marshall, contain afferent neurons from the ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2009.07.029

    authors： Nakagawa H,Scherlag BJ,Patterson E,Ikeda A,Lockwood D,Jackman WM

    更新日期：2009-12-01 00:00:00

  • Distinctive property and pharmacology of voltage-gated sodium current in rat atrial vs ventricular myocytes.

    abstract：BACKGROUND:Several mammalian species display distinct biophysical properties between atrial and ventricular voltage-gated sodium current (INa); however, the potential mechanism behind this phenomenon is unknown. OBJECTIVE:The purpose of this study was to investigate the potential molecular identities of the different ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2015.11.022

    authors： Chen KH,Xu XH,Sun HY,Du XL,Liu H,Yang L,Xiao GS,Wang Y,Jin MW,Li GR

    更新日期：2016-03-01 00:00:00

  • Interatrial conduction can be accurately determined using standard 12-lead electrocardiography: validation of P-wave morphology using electroanatomic mapping in man.

    abstract：BACKGROUND:Different P-wave morphologies during sinus rhythm as displayed on standard ECGs have been postulated to correspond to differences in interatrial conduction. OBJECTIVE:The purpose of this study was to evaluate the hypothesis by comparing P-wave morphologies using left atrial activation maps. METHODS:Twenty-...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2007.12.017

    authors： Holmqvist F,Husser D,Tapanainen JM,Carlson J,Jurkko R,Xia Y,Havmöller R,Kongstad O,Toivonen L,Olsson SB,Platonov PG

    更新日期：2008-03-01 00:00:00

  • Evaluation of morphology discrimination for ventricular tachycardia diagnosis in implantable cardioverter-defibrillators.

    abstract：BACKGROUND:To reduce inappropriate therapy from implantable cardioverter-defibrillators (ICDs), electrogram morphology discrimination has been developed to improve arrhythmia discrimination without compromising device safety. OBJECTIVES:The purpose of this study was to determine the accuracy of the morphology discrimi...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2006.06.034

    authors： Theuns DA,Rivero-Ayerza M,Goedhart DM,van der Perk R,Jordaens LJ

    更新日期：2006-11-01 00:00:00

  • Does the number of simultaneously activated electrodes during phased RF multielectrode ablation of atrial fibrillation influence the incidence of silent cerebral microembolism?

    abstract：BACKGROUND:Asymptomatic cerebral embolus (ACE) detected by diffusion-weighted magnetic resonance imaging (DW-MRI) following atrial fibrillation (AF) ablation has been reported at varying rates with different ablation techniques. OBJECTIVE:To evaluate the incidence of ACE after phased radiofrequency ablation for AF wit...

    journal_title：Heart rhythm

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.hrthm.2013.04.005

    authors： Wieczorek M,Hoeltgen R,Brueck M

    更新日期：2013-07-01 00:00:00

  • Application of noninvasive signal-averaged electrocardiogram analysis in predicting the requirement of epicardial ablation in patients with arrhythmogenic right ventricular cardiomyopathy.

    abstract：BACKGROUND:Signal-averaged electrocardiogram (SAECG) provides not only diagnostic information but also the prognostic implication of ablation in arrhythmogenic right ventricular cardiomyopathy (ARVC). OBJECTIVE:This study aimed to validate the role of SAECG in identifying arrhythmogenic substrates requiring an epicard...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2019.11.018

    authors： Chung FP,Lin CY,Lin YJ,Chang SL,Lo LW,Hu YF,Tuan TC,Chao TF,Liao JN,Chang TY,Tan VH,Kuo L,Wu CI,Liu CM,Vicera JJB,Chen CC,Chin CG,Liu SH,Cheng WH,Chou CY,Lugtu IC,Liu CH,Chen SA

    更新日期：2020-04-01 00:00:00

  • Spectral analysis during sinus rhythm predicts an abnormal atrial substrate in patients with paroxysmal atrial fibrillation.

    abstract：BACKGROUND:Regions of rapid and multiple deflections can be identified with high dominant frequency (DF) during sinus rhythm (SR). These areas may play a role in the perpetuation of atrial fibrillation (AF) and indicate an atrial substrate abnormality. OBJECTIVE:The purpose of this study was to investigate the atrial ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2008.03.039

    authors： Lin YJ,Kao T,Tai CT,Chang SL,Lo LW,Tuan TC,Udyavar AR,Hu YF,Tso HW,Higa S,Chen SA

    更新日期：2008-07-01 00:00:00

  • High-frequency powers hidden within QRS complex as an additional predictor of lethal ventricular arrhythmias to ventricular late potential in post-myocardial infarction patients.

    abstract：BACKGROUND:Ventricular late potentials (VLPs) have been known to be a predictor of lethal ventricular arrhythmias (L-VAs); however, detection of other arrhythmogenic signals within the QRS complex remains obscure. OBJECTIVE:The aim of this study was to evaluate whether abnormal intra-QRS high-frequency powers (IQHFP) ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2011.06.027

    authors： Tsutsumi T,Takano N,Matsuyama N,Higashi Y,Iwasawa K,Nakajima T

    更新日期：2011-10-01 00:00:00