Abstract：
:Disseminated cryptococcosis is a rare and often fatal disease in children. The majority of cases usually occur in individuals with defective cell-mediated immunity, most commonly due to HIV infection. The authors here in report an 8-year-old girl from Nepal who presented with fever, cough, headache, lymphadenopathy, hepatosplenomegaly and cutaneous lesions. Lymph node biopsy revealed multiple granulomas composed of histiocytes and epitheliold cells along with numerous yeast forms of cryptococcus. Cultures of CSF, sputum and urine yielded cryptococcus neoformans. Surprisingly,the immune function in terms of T-cell number, CD4 : CD8 ratio, serum immunoglobulins and HIV serology was normal. After the diagnosis of disseminated cryptococcosis was established, the patient was treated with 5-fluorocytosine (100 mg/kg/day) for initial two weeks and amphotericin B (1 mg/kg/day) for 13 weeks. Patient responded well to the treatment with disappearance of presenting symptoms, cutaneous lesions, and lymphadenopathy, though she still had hepatosplenomegaly, which also decreased. Unfortunately, she developed loss of vision in 10th week of therapy. The patient was discharged on oral fluconazole (6 mg/kg/day) and no recurrence was found during the follow-up period of more than 9 months. This is the first case of disseminated cryptococcosis with no detectable immune deficit, from India.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Chaudhary MW,Sardana K,Kumar P,Dewan V,Anand VKkeywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
85issue
1eissn
0019-5456issn
0973-7693journal_volume
72pub_type
杂志文章abstract：:Psychosocial and mental health problems are quite prevalent among adolescent worldwide, some data reporting up to 20% of adolescents having such problems. A number of risk factors, familial, individual and societal, have been indentified as contributing to these problems in adolescents. There are also many factors, su...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02723793
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:The study was performed to investigate the level of serum cardiac troponin I (cTnI), a specific marker for myocardial cell damage, in the acute rheumatic carditis (RC). METHODS:Twenty seven consecutive patients with acute RC and 23 healthy children were enrolled. RESULT:cTnI level in both groups showed no s...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02722592
更新日期：2001-10-01 00:00:00
abstract：:The authors report 22 patients of Kawasaki disease, diagnosed and treated over a period of 3 years at a tertiary care centre in New Delhi. Ten cases fullfiled the criteria of a "classical" case while 12 cases were "incomplete" cases. Echocardiography was performed in all cases and coronary artery involvement was found...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-010-0356-y
更新日期：2011-04-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-017-2359-4
更新日期：2017-07-01 00:00:00
abstract：:Tetanus is still an important cause of morbidity and mortality in developing countries. Fifty two patients with tetanus were admitted within a 15 year period to our hospital, and 24 of them died. The remaining cases were called for re-evaluation 3-13 years after the infection. Only 10 cases were admitted again, and 6 ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02752221
更新日期：1994-05-01 00:00:00
abstract：:A 5-year-old child presented with the second episode of meningitis when we started investigating her to find a cause for recurrent episode of meningitis. During this she suffered from a third attack after which she was diagnosed as having isolated C(3) deficiency. She was put on penicillin prophylaxis and vaccinated a...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-009-0036-y
更新日期：2009-01-01 00:00:00
abstract：:Since transplacental immunity and waning of maternally derived measles specific antibodies play an important role in determining the optimum age for vaccination of infants against measles, a study was carried out in which 150 paired samples and 581 infant serum samples were tested for measles specific antibodies. Out ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02752192
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:To describe the clinical profile of Hand Foot and Mouth Disease (HFMD) like illness in a cluster of cases. METHODS:Children presenting with papulovesicular skin lesions with or without oral lesions were clinically examined, treated and followed up. RESULTS:Out of 21 cases, 18 (85.7%) were less than 3y and 1...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-016-2271-3
更新日期：2017-03-01 00:00:00
abstract：:Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by ectopic bone formation involving the connective tissues leading to severe skeletal manifestations. The genetic defect in this disorder has not been characterized in Indian patients till date. The authors report three cases of FOP a...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-013-1117-5
更新日期：2014-06-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02730902
更新日期：1998-07-01 00:00:00
abstract：: ...
journal_title：Indian journal of pediatrics
pub_type： 信件
doi：10.1007/s12098-018-2702-4
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:To investigate the presence of Y-chromosome sequences and determine their frequency in patients with Turner syndrome. METHODS:The study included 23 patients with Turner syndrome from Brazil, who gave written informed consent for participating in the study. Cytogenetic analyses were performed in peripheral b...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-015-1929-6
更新日期：2016-05-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02761205
更新日期：1999-03-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-010-0020-6
更新日期：2010-05-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-011-0582-y
更新日期：2012-03-01 00:00:00
abstract：:The idea that nutrition in early life (such as before conception, during pregnancy and in infancy) can influence, or programme, long-term health, known as the 'Developmental Origins of Health and Disease Hypothesis', has generated great scientific interest. This concept is particularly relevant for the development of ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-017-2554-3
更新日期：2018-06-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-018-2753-6
更新日期：2019-02-01 00:00:00
abstract：:Nutrition plays a vital role in maintaining and enhancing the health of an individual. As mortality within intensive care units declines because of increased expertise and better equipment, attention is being focused on better methods of feeding the critically ill child. Feeding the child is one aspect that has been r...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02721839
更新日期：2001-04-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 临床试验,杂志文章
doi：10.1007/BF02823873
更新日期：1996-01-01 00:00:00
abstract：:Nutritional support to patients in neonatal and pediatric intensive care units is critical not only to minimize negative nitrogen balance but also to promote growth and development. Continuous technological and logistical advances in the Western countries have improved the efficacy and reduced the complications of par...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02730722
更新日期：2004-09-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-011-0401-5
更新日期：2011-08-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-018-02851-x
更新日期：2019-06-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-011-0456-3
更新日期：2011-11-01 00:00:00
abstract：:Osteopetrosis is a collective term for a range of sclerosing bone diseases resulting from an absence or defective function of osteoclasts. The clinical expression is variable and includes skeletal, hematological and neurological manifestations. The common neurological manifestation includes cranial neuropathies involv...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-007-0070-6
更新日期：2007-04-01 00:00:00
abstract：:Although hypersensitivity to foods is often linked to exacerbations of symptoms of respiratory allergy, no such information is available regarding the foods traditionally considered to play a probable etiological role in respiratory allergy in India, which are in fact quite different from the ones implicated in the We...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02723925
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVES:The authors measured and recorded the physical (outdoor playing) and mental (home study) activity behavior and blood pressure amongst school going children and observed their association with the blood pressure levels. METHOD:It was a cross sectional school-based study from 12 primary schools; selected by s...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/BF02724095
更新日期：2004-04-01 00:00:00
abstract：:Iron overload is a serious and potentially fatal condition that results from multiple blood transfusions required over a long period of time to treat certain types of anemias such as, that caused by beta-thalassemia, sickle cell disease and myelodysplastic syndrome. Deferoxamine, which has been used since four decades...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-010-0030-4
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVE:To study the etiological profile of patients with acute febrile encephalopathy syndrome focusing chiefly on the viral etiology, and to correlate clinical and radiological features of patients with viral encephalitis. METHODS:A prospective hospital based study conducted on the consecutive patients admitted in...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-008-0150-2
更新日期：2008-08-01 00:00:00
abstract：:A 11-year-old girl presented with thrombocytopenic purpura along with cervical lymphadenopathy. There was no hepatosplenomegaly; no evidence of microangiopathy; bone marrow examination was normal. Acid fast bacilli were seen in fine needle aspiration cytology of the lymph node. A diagnosis of tubercular lymphadenitis ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02723827
更新日期：2003-12-01 00:00:00
