当前位置： SCI文献检索 > JOURNAL OF INSECT PHYSIOLOGY期刊下所有文献 > The NMDA receptor antagonist MK-801 inhibits vitellogenesis in the flesh fly Neobellieria bullata and in the desert locust Schistocerca gregaria.

The NMDA receptor antagonist MK-801 inhibits vitellogenesis in the flesh fly Neobellieria bullata and in the desert locust Schistocerca gregaria.

Abstract：

:We found that in the flesh fly Neobellieria bullata, vitellogenesis can be inhibited in a dose-dependent way by two injections of 60 microg MK-801/g body mass. In the desert locust Schistocerca gregaria, vitellogenesis can also be fully inhibited but only by repeated injections of 200-400 microg/g body mass. In this species, the inhibition can be overruled by coapplication of juvenile hormone. Vitellogenin bands remained visible in electropherograms of hemolymph of MK-801-treated female locusts, but vitellogenin did not accumulate as might be expected when only its uptake by the oocytes, and not its synthesis by the fat body, would be affected. Whether MK-801 acts by inhibiting juvenile hormone synthesis by the corpora allata remains to be investigated.

journal_name

J Insect Physiol

journal_title

Journal of insect physiology

authors

Begum M,Breuer M,Kodrik D,M Rahman M,De Loof A

doi

10.1016/j.jinsphys.2004.07.003

keywords:

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

927-34

issue

10

eissn

0022-1910

issn

1879-1611

pii

S0022-1910(04)00128-3

journal_volume

50

pub_type

杂志文章

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