Abstract:
STUDY DESIGN:An in vitro biomechanical investigation to quantify the endplates resistance to compressive loads, in the thoracic and lumbar spine. Comparisons were made to determine the regional strength of the endplate, the optimal size and geometry of interbody support, and the effects of endplate removal on structural strength. OBJECTIVES:To biomechanically assess the regional variation of endplate strength in the thoracic and lumbar spine, the optimal geometry and cross-sectional area for structural interbody support, and endplate preparation techniques with respect to endplate failure or subsidence. SUMMARY OF BACKGROUND DATA:Anterior column interbody support plays an important role in spinal reconstruction. Subsidence of interbody structural support is a common problem and may be related to regional weakness of the endplate, the size and/or geometry of structural support, and the preparation of the endplate. Biomechanical data related to these issues should be of importance to spine surgeons and reduce the risk of subsidence and its inherent complications. METHODS:The indentation tests were performed in three subgroups, each with a different set of test variables. The first test consisted of 65 vertebrae at six different endplate test positions using a 9.53-mm diameter indenter. The second test was performed on 48 vertebrae at a central endplate test site using three hollow and two solid cylindrical indenters of varying diameter. The third test was done using 24 vertebrae with the endplate intact, partially removed, or fully removed. All tests were run using human cadaveric specimen using both the superior and inferior endplates. The maximum load to failure (MLF) was determined for each test performed. RESULTS:For all levels tested, the highest MLF occurred in the posterolateral region of the endplate. The lowest value occurred in the central and anterocentral regions for levels T7-L5 and T1-T6, respectively. Hollow indenters with a small diameter had the lowest MLF, whereas solid large-diameter indenters had the highest MLF. The ultimate compressive strength for all hollow indenters was significantly higher than all solid indenters. There was a significant reduction in the endplate strength with the complete removal of the endplate. CONCLUSIONS:The posterolateral region of the endplate provides the greatest resistance to subsidence while the central region provides the least resistance. A larger-diameter solid support has the greater MLF and the lower the risk of subsidence, suggesting a more efficient transfer of force to the endplate with the hollow indenters. Parameters such as the geometry of structural support and the position and preparation of the endplate can influence the resistance of an interbody support to subside. Partial removal of the endplate may provide both, for adequate mechanical advantage and a highly vascular site for fusion.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Lowe TG,Hashim S,Wilson LA,O'Brien MF,Smith DA,Diekmann MJ,Trommeter Jdoi
10.1097/01.brs.0000143623.18098.e5keywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
2389-94issue
21eissn
0362-2436issn
1528-1159pii
00007632-200411010-00009journal_volume
29pub_type
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