An outcomes analysis of the treatment of cervical pseudarthrosis with posterior fusion.

Abstract:

STUDY DESIGN:A retrospective review of 33 consecutive patients treated with posterior fusion and selective nerve root decompression for the treatment of pseudarthrosis following anterior cervical discectomy and fusion. OBJECTIVES:Use standardized outcome measures to evaluate the results of posterior fusion with selective nerve root decompression as a treatment option for symptomatic pseudarthrosis of the cervical spine. SUMMARY OF BACKGROUND DATA:Pseudarthrosis after anterior cervical discectomy and fusion has been recognized as a cause of continued cervical pain and unsatisfactory outcomes. Debate continues as to whether a revision anterior approach or a posterior fusion procedure is the best treatment for symptomatic cervical pseudarthrosis. To our knowledge, standardized outcome measures have not been used to evaluate the results of either surgical treatment option; therefore, it is difficult to evaluate outcomes in these patients, let alone compare surgical treatment options. Data on fusion rates in these two surgical treatment groups suggest a trend of a higher fusion rate with utilization of a posterior revision procedure, but the largest study to date includes the study of only 19 patients treated with a posterior fusion. METHODS:Thirty-three consecutive patients with symptomatic pseudarthrosis following anterior cervical discectomy and fusion were treated with selective nerve root decompression and posterior fusion using iliac crest or local bone graft as well as posterior wiring and/or lateral mass plating. The average follow-up period was 46 months (range, 20-86 months). Patients were assessed using physical examination, flexion-extension lateral radiographs, and standardized outcome measures including the SF-36, Arthritis Impact Measurement Scales 2, and Cervical Spine Outcomes Questionnaire. RESULTS:All 33 patients (100%) demonstrated a solid fusion at their most recent follow-up, and all 33 patients noted significant improvement in their preoperative symptoms. No difference in fusion status was noted between those treated with iliac crest versus patients treated with local bone graft--all had a solid fusion; 72% of the patients were satisfied with the result of their surgery. Cervical Spine Outcomes Questionnaire pain scales demonstrated 52% of patients reported mild or nopain at follow-up, whereas 20% described their pain as "discomforting" and 28% of the patients continued to report moderate to severe pain. CONCLUSIONS:This is the first study to our knowledge to use standardized outcome measures to assess clinical outcome in patients treated with posterior fusion for pseudarthrosis after anterior cervical discectomy and fusion. Patients and surgeons need to understand the potential for success with this revision procedure but also be aware of the relatively high rate of continued moderate to severe pain observed in this patient population even after a solid fusion is achieved. All of the patients in this study fused with a single posterior fusion procedure, further supporting the relatively higher fusion rates observed in the literature using posterior fusion as a treatment for cervical pseudarthrosis. Our results also support the ability of surgeons to use local bone graft without iliac crest in a posterior fusion for cervical pseudarthrosis and therefore avoid the morbidity associated with iliac crest bone graft harvest.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Kuhns CA,Geck MJ,Wang JC,Delamarter RB

doi

10.1097/01.brs.0000184314.26543.7d

keywords:

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

2424-9

issue

21

eissn

0362-2436

issn

1528-1159

pii

00007632-200511010-00014

journal_volume

30

pub_type

杂志文章

相关文献

SPINE文献大全
  • Esophageal perforation with a locking screw: a case report and review of the literature.

    abstract:STUDY DESIGN:A case report with a review of the literature. OBJECTIVES:Anterior cervical spine surgery (ACS) has received widespread acceptance, and as a result, a variety of complications have been reported. Several cases of esophageal complications, arising from the use of various implants and grafts, have been desc...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e318074d56c

    authors: Nourbakhsh A,Garges KJ

    更新日期:2007-07-01 00:00:00

  • Back extension endurance and strength: the effect of variable-angle roman chair exercise training.

    abstract:STUDY DESIGN:A pre- and postintervention randomized, controlled trial was conducted. OBJECTIVE:To evaluate the effect of progressive resistance exercise training using a variable-angle Roman chair on the development of lumbar extensor endurance and strength. SUMMARY OF BACKGROUND DATA:Progressive resistance exercise ...

    journal_title:Spine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00007632-200208150-00016

    authors: Verna JL,Mayer JM,Mooney V,Pierra EA,Robertson VL,Graves JE

    更新日期:2002-08-15 00:00:00

  • Use of Higher-strength Opioids has a Dose-Dependent Association With Reoperations After Lumbar Decompression and Interbody Fusion Surgery.

    abstract:STUDY DESIGN:A retrospective cohort study. OBJECTIVE:The aim of this study was to identify an association between preoperative opioid use and reoperations rates. SUMMARY OF BACKGROUND DATA:Chronic opioid use is a public health crisis in the United States and has been linked to worse outcomes after lumbar spine surger...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000003751

    authors: Samuel AM,Lovecchio FC,Premkumar A,Louie PK,Vaishnav AS,Iyer S,McAnany SJ,Albert TJ,Gang CH,Qureshi SA

    更新日期:2021-02-01 00:00:00

  • Risk of blood contamination of health care workers in spine surgery. A study of 324 cases.

    abstract:STUDY DESIGN:The relative risk of blood contamination during spine surgery was studied using data collected from 324 procedures. OBJECTIVES:To analyze demographic factors that predict blood-borne pathogens in the population of spine surgery patients, study the rates and patterns of blood contamination in health care w...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199806010-00018

    authors: Wong DA,Jones AA,Lange K

    更新日期:1998-06-01 00:00:00

  • Spinal-thoracic dumbbell meningioma: a case report.

    abstract:STUDY DESIGN:Total excision of a large dumbbell cervicothoracic intra- and extraspinal meningioma that had grown into the posterior mediastinum is described. This excision involved a two-step neurosurgical-thoracosurgical procedure within a short interval. OBJECTIVES:To document that the described laminectomy and thor...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-200107010-00026

    authors: Buchfelder M,Nomikos P,Paulus W,Rupprecht H

    更新日期:2001-07-01 00:00:00

  • Incidence and aggravation of cervical spine instabilities in rheumatoid arthritis: a prospective minimum 5-year follow-up study of patients initially without cervical involvement.

    abstract:STUDY DESIGN:A prospective minimum 5-year follow-up study of the cervical spine in patients with rheumatoid arthritis (RA) initially without cervical involvement. OBJECTIVE:To clarify the incidence and aggravation of cervical spine instabilities and their predictive risk factors in patients with RA. SUMMARY OF BACKGR...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e31826def1c

    authors: Yurube T,Sumi M,Nishida K,Miyamoto H,Kohyama K,Matsubara T,Miura Y,Sugiyama D,Doita M,Kobe Spine Conference.

    更新日期:2012-12-15 00:00:00

  • Feasibility Study of Utilization of Action Camera, GoPro Hero 4, Google Glass, and Panasonic HX-A100 in Spine Surgery.

    abstract:STUDY DESIGN:Study for feasibility of commercially available action cameras in recording video of spine. OBJECTIVE:Recent innovation of the wearable action camera with high-definition video recording enables surgeons to use camera in the operation at ease without high costs. The purpose of this study is to compare the...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000001719

    authors: Lee CK,Kim Y,Lee N,Kim B,Kim D,Yi S

    更新日期:2017-02-15 00:00:00

  • Analysis of risk factors associated with fusion failure after anterior odontoid screw fixation.

    abstract:STUDY DESIGN:Retrospective study. OBJECTIVE:To evaluate the incidence of fusion failure after anterior screw fixation of type II and rostral shallow type III fractures and to identify related risk factors. SUMMARY OF BACKGROUND DATA:Although several studies have reported fusion rates after anterior odontoid screw fix...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e31820e6418

    authors: Cho DC,Sung JK

    更新日期:2012-01-01 00:00:00

  • Long-term results from in situ fusion for congenital vertebral deformity.

    abstract:STUDY DESIGN:Retrospective review of long-term outcome of fusion in situ for congenital vertebral anomaly with particular emphasis on cosmesis and the incidence of reoperation. OBJECTIVE:Examination of the success rate of this procedure and of risk factors for failure. BACKGROUND:Fusion in situ is the accepted prophy...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-200203150-00011

    authors: Goldberg CJ,Moore DP,Fogarty EE,Dowling FE

    更新日期:2002-03-15 00:00:00

  • Microlumbar discectomy: followup of 147 patients.

    abstract::Microlumbar discectomy is a new surgical technique for the treatment of herniated lumbar disc. The operating microscope and special instruments enable the surgeon to remove the herniated portion of the disc without laminectomy through a 1-inch skin incision. A transfusion was never necessary. In a followup study of 14...

    journal_title:Spine

    pub_type: 杂志文章

    doi:

    authors: Goald HJ

    更新日期:1978-06-01 00:00:00

  • Occupational recovery after open-door type laminoplasty for patients with ossification of the posterior longitudinal ligament.

    abstract:STUDY DESIGN:A cross-sectional survey of occupational recovery after surgery with patients who had ossification of the posterior longitudinal ligament. OBJECTIVES:To evaluate occupational recovery after open-door type laminoplasty for patients with ossification of the posterior longitudinal ligament. SUMMARY OF BACKG...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.BRS.0000083206.24176.C8

    authors: Kamizono J,Matsunaga S,Hayashi K,Shinkura R,Koriyama C,Sakou T,Komiya S

    更新日期:2003-08-15 00:00:00

  • Association Between Neurotrophic Factor Expression and Pain-Related Behavior Induced by Nucleus Pulposus Applied to Rat Nerve Root.

    abstract:STUDY DESIGN:An experimental animal study. OBJECTIVE:To investigate the relationship between pain-related behavior and the expression of neurotrophic factors in the dorsal root ganglion (DRG) and spinal cord (SC) using a nucleus pulposus (NP) rat model. SUMMARY OF BACKGROUND DATA:Neurotrophic factors are released fro...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000002223

    authors: Seki S,Sekiguchi M,Konno SI

    更新日期:2018-01-01 00:00:00

  • Opioid Use in Adults With Low Back or Lower Extremity Pain Who Undergo Spine Surgical Treatment Within 1 Year of Diagnosis.

    abstract:STUDY DESIGN:Retrospective longitudinal cohort. OBJECTIVE:We investigated opioid prescribing patterns amongst adults in the United States diagnosed with low back or lower extremity pain (LBP/LEP) who underwent spine surgery. SUMMARY OF BACKGROUND DATA:Opioid-based treatment of LBP/LEP and postsurgical pain has separa...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000003663

    authors: Fatemi P,Zhang Y,Ho A,Lama R,Jin M,Veeravagu A,Desai A,Ratliff JK

    更新日期:2020-12-15 00:00:00

  • Effects of a media campaign on back beliefs is sustained 3 years after its cessation.

    abstract:STUDY DESIGN:Quasi-experimental, nonrandomized, nonequivalent, parallel group-controlled study involving before and after telephone surveys of the general population. OBJECTIVE:To measure the magnitude of any sustained change in population beliefs about back pain 3 years after cessation of a population-based intervent...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.brs.0000164121.77862.4b

    authors: Buchbinder R,Jolley D

    更新日期:2005-06-01 00:00:00

  • Analysis of rabbit intervertebral disc physiology based on water metabolism. II. Changes in normal intervertebral discs under axial vibratory load.

    abstract::Metabolic changes induced by axial vibratory load to the spine were investigated based on water metabolism in normal intervertebral discs of rabbits with or without pentobarbital anesthesia. Tritiated water concentration in the intervertebral discs of unanesthetized rabbits was reduced remarkably by axial vibration fo...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-198811000-00016

    authors: Hirano N,Tsuji H,Ohshima H,Kitano S,Itoh T,Sano A

    更新日期:1988-11-01 00:00:00

  • Finite element analysis of the effects of pedicle screw fixation nut loosening on lumbar interbody fusion based on the elasto-plateau plasticity of bone characteristics.

    abstract:STUDY DESIGN:Cylindrical cages and pedicle screw fixation (PSF) have been used for the setting of a lumbar interbody fusion. OBJECTIVE:To investigate the effects of PSF-nut loosening on lumbar interbody fusion based on the elasto-plateau plasticity of bone characteristics. SUMMARY OF BACKGROUND DATA:The stress-strain...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3181b6258a

    authors: Kim Y,Kim TW

    更新日期:2010-03-15 00:00:00

  • Survivorship analysis of VSP spine instrumentation in the treatment of thoracolumbar and lumbar burst fractures.

    abstract::We used survivorship analysis to study 21 burst fractures that were treated with posterior VSP spine implant and fusion, each of which was over two motion segments. There were two treatment classes: 1) eight patients whose surgery included anterior bone grafting (augmentation), seven of which were done by the transped...

    journal_title:Spine

    pub_type: 杂志文章

    doi:

    authors: Ebelke DK,Asher MA,Neff JR,Kraker DP

    更新日期:1991-08-01 00:00:00

  • Development of degenerative spondylosis of the lumbar spine after partial discectomy. Comparison of laminotomy, discectomy, and posterolateral discectomy.

    abstract:STUDY DESIGN:The development of degenerative spondylosis after successful operative decompression of the affected nerve root was prospectively evaluated in a comparative case series of 100 patients with a herniated lumbar nucleus pulposus. OBJECTIVES:The objective of this study was to compare the relative incidence of...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199503010-00018

    authors: Kambin P,Cohen LF,Brooks M,Schaffer JL

    更新日期:1995-03-01 00:00:00

  • Effect of altering titer, serotype, and promoter in recombinant adenoassociate virus gene therapy expression of spinal cord neurons and astrocytes.

    abstract:STUDY DESIGN:Descriptive histologic analysis of spinal cord gene therapy. OBJECTIVE:To maximize protein expression in rat spinal cord using recombinant adenoassociate virus viral vector. SUMMARY OF BACKGROUND DATA:There are few reports of spinal cord genetic transfer. There have been no reports that compare technique...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.brs.0000147909.59083.da

    authors: Harrop JS,Poulsen DJ,Xiao W,Freese A,During MJ

    更新日期:2004-12-15 00:00:00

  • Effect of intensive training on the isokinetic strength and structure of lumbar muscles in patients with chronic low back pain.

    abstract:STUDY DESIGN:This study investigated the effects of the intensive physical rehabilitation program on the trunk and knee extensor muscles in patients with chronic low back pain. At baseline and after 3 months, strength was measured and muscle biopsies were taken. OBJECTIVES:To evaluate the effects of strength exercises...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199502000-00014

    authors: Rissanen A,Kalimo H,Alaranta H

    更新日期:1995-02-01 00:00:00

  • The Feature of Clinical and Radiographic Outcomes in Elderly Patients With Cervical Spondylotic Myelopathy: A Prospective Cohort Study on 1025 Patients.

    abstract:STUDY DESIGN:A prospective cohort study. OBJECTIVE:The purpose of this study was to compare the surgical outcomes between nonelderly and elderly patients with cervical spondylotic myelopathy (CSM) and to characterize the preoperative symptoms and postoperative residual symptoms in elderly patients. SUMMARY OF BACKGRO...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000002446

    authors: Machino M,Ando K,Kobayashi K,Ito K,Tsushima M,Matsumoto A,Morozumi M,Tanaka S,Ito K,Kato F,Nishida Y,Ishiguro N,Imagama S

    更新日期:2018-06-15 00:00:00

  • Mechanical modulation of vertebral body growth. Implications for scoliosis progression.

    abstract:STUDY DESIGN:The authors developed a rat-tail model to investigate the hypothesis that vertebral wedging during growth in progressive spinal deformities results from asymmetric loading in a "vicious cycle." OBJECTIVES:To document growth curves with axial compression or distraction applied to tail vertebrae to determin...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199605150-00007

    authors: Stokes IA,Spence H,Aronsson DD,Kilmer N

    更新日期:1996-05-15 00:00:00

  • Human nucleus pulposis can respond to a pro-inflammatory stimulus.

    abstract:STUDY DESIGN:Disc tissue obtained from patients undergoing surgery for scoliosis, lumbar radiculopathy, and discogenic pain was cultured under basal and lipopolysaccharide-stimulated conditions and the medium analyzed for production of a range of pro-inflammatory mediators. OBJECTIVES:This study was conducted to confi...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.BRS.0000103341.45133.F3

    authors: Burke JG,G Watson RW,Conhyea D,McCormack D,Dowling FE,Walsh MG,Fitzpatrick JM

    更新日期:2003-12-15 00:00:00

  • Cutaneous silent periods in the assessment of mild cervical spondylotic myelopathy.

    abstract:STUDY DESIGN:Clinical, neuroradiologic, and neurophysiologic description of 21 patients with compressive cervical spondylotic myelopathy (CCSM). OBJECTIVE:To describe the utility of cutaneous silent periods (CSPs) for functional evaluation of mild CCSM. SUMMARY OF BACKGROUND DATA:Electroneurography, electromyography,...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e31818f8be3

    authors: Stetkarova I,Kofler M

    更新日期:2009-01-01 00:00:00

  • Changes in the lumbar spine of athletes from supine to the true-standing position in magnetic resonance imaging.

    abstract:STUDY DESIGN:Case-control observational study. OBJECTIVE:Determination of dimensional changes in the lumbar spines of athletes between supine and stand-up position in MRI, concerning the lordosis, spinal canal cross-sectional area (SCCA), dural sac cross-sectional area (DSCA), sagittal dural sac diameter (SDSD), the l...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3181bdb2d3

    authors: Mauch F,Jung C,Huth J,Bauer G

    更新日期:2010-04-20 00:00:00

  • Percutaneous trephine bone biopsy of the thoracic spine.

    abstract::The authors performed six consecutive percutaneous trephine biopsies of the thoracic spine under local anesthesia, using computed tomography to localize lesions and guide needle placement. The details of the technique are illustrated. Complications were not found. The authors conclude that closed large needle biopsy o...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-198510000-00008

    authors: Mick CA,Zinreich J

    更新日期:1985-10-01 00:00:00

  • Differences in standing and forward bending in women with chronic low back or pelvic girdle pain: indications for physical compensation strategies.

    abstract:STUDY DESIGN:This cohort study compares motion characteristics during forward bending of a group of chronic female patients either with low back pain (LBP) or pelvic girdle pain (PGP) and healthy subjects using computer-video analysis. OBJECTIVE:This study determines whether subcategories of back pain patients could b...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e318170fcf6

    authors: van Wingerden JP,Vleeming A,Ronchetti I

    更新日期:2008-05-15 00:00:00

  • Relationship between subjective neck disorders and cervical spine mobility and motion-related pain in male machine operators.

    abstract:STUDY DESIGN:In a single blinded procedure, quantified cervical clinical tests were performed on machine operators with and without subjective reports of neck pain. OBJECTIVES:To evaluate whether subjective reports of neck pain are associated with limited and painful cervical spine mobility. SUMMARY OF BACKGROUND DAT...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199707010-00015

    authors: Hagen KB,Harms-Ringdahl K,Enger NO,Hedenstad R,Morten H

    更新日期:1997-07-01 00:00:00

  • Results of surgical treatment of adult idiopathic scoliosis with low back pain and spinal stenosis: a study of long-term clinical radiographic outcomes.

    abstract:STUDY DESIGN:A case series of adults with surgical treatment for adult idiopathic thoracolumbar and/or lumbar scoliosis, low back pain, and spinal stenosis was studied. OBJECTIVE:To assess pain relief, curve correction, and complications after combined procedures consisting of decompression, spine fusion, and stabiliz...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.BRS.0000048502.62793.0C

    authors: Shapiro GS,Taira G,Boachie-Adjei O

    更新日期:2003-02-15 00:00:00

  • Temporary external transpedicular fixation of the lumbosacral spine: a prospective, longitudinal study in 330 patients.

    abstract:STUDY DESIGN:In this study, 330 patients with incapacitating low back pain underwent temporary external transpedicular fixation (TETF) of the lumbosacral spine in a prospective trial. OBJECTIVE:To evaluate TETF as a test for selecting suitable candidates for segmental spinal fusion. SUMMARY OF BACKGROUND DATA:Few stu...

    journal_title:Spine

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.brs.0000190868.57106.4d

    authors: Elmans L,Willems PC,Anderson PG,van Limbeek J,de Kleuver M,van der Schaaf D

    更新日期:2005-12-15 00:00:00