Role of Sirt1 Plays in Nucleus Pulposus Cells and Intervertebral Disc Degeneration.

abstract：STUDY DESIGN:Cost-effectiveness analysis with decision analysis and meta-analysis. OBJECTIVE:To determine the relative cost-effectiveness of anterior cervical discectomy with fusion (with autograft, allograft, or spacers), anterior cervical discectomy without fusion (ACD), and cervical disc replacement (CDR) for the t...

journal_title：Spine

authors： Lewis DJ,Attiah MA,Malhotra NR,Burnett MG,Stein SC

更新日期：2014-12-01 00:00:00

abstract：STUDY DESIGN:Laboratory/animal-based proof of principle study. OBJECTIVE:To validate the accuracy of a magnetic resonance imaging (MRI)-guided stereotactic system for intraspinal electrode targeting and demonstrate the feasibility of such a system for controlling implantation of intraspinal electrodes. SUMMARY OF BAC...

journal_title：Spine

authors： Grahn PJ,Goerss SJ,Lujan JL,Mallory GW,Kall BA,Mendez AA,Trevathan JK,Felmlee JP,Bennet KE,Lee KH

更新日期：2016-07-01 00:00:00

abstract：STUDY DESIGN:Case report and literature review. OBJECTIVES:Clinicians use methylmethacrylate vertebroplasty to treat vertebral hemangiomas, metastases, and osteoporotic fractures. Cement may leak out of the vertebral body and compress the adjacent spinal cord and nerve roots. We review a case of nerve-root and cord co...

journal_title：Spine

authors： Ratliff J,Nguyen T,Heiss J

更新日期：2001-07-01 00:00:00

abstract：STUDY DESIGN:A prospective cohort study of Cobb angles (CA) and apical vertebral rotations (AVR) in 25 patients who had adolescent idiopathic scoliosis. OBJECTIVE:To assess in vivo the concomitant vertebral derotation occurring with correction of scoliosis deformity as a result of coupling effect by using the fulcrum ...

journal_title：Spine

authors： Luk KD,Cheung WY,Wong Y,Cheung KM,Wong YW,Samartzis D

更新日期：2012-07-01 00:00:00

abstract：STUDY DESIGN:Prospective, longitudinal cohort (nonrandomized). OBJECTIVE:To compare thoracoplasty (Th), direct vertebral body derotation (DVBD), and Th and DVBD with respect to correction of the rib prominence and Scoliosis Research Society (SRS) self-image scores in patients undergoing surgery for adolescent idiopath...

journal_title：Spine

authors： Samdani AF,Hwang SW,Miyanji F,Lonner B,Marks MC,Sponseller PD,Newton PO,Cahill PJ,Shufflebarger HL,Betz RR

更新日期：2012-06-15 00:00:00

abstract：:Flexibility of the porcine lumbosacral spine was measured after application of six different types of surgical instrumentation, and in a control state. Fifteen adult pig spines were tested with flexion, extension, lateral bending, and axial rotation torques applied to the upper end with the pelvis fixed. Instrumentati...

journal_title：Spine

authors： Asazuma T,Stokes IA,Moreland MS,Suzuki N

更新日期：1990-11-01 00:00:00

abstract：STUDY DESIGN:Three-dimensional (3D) analysis of the spinopelvic alignment in adolescent idiopathic scoliosis (AIS). OBJECTIVE:To study the 3D pelvic alignment with respect to the spinal deformities in AIS subgroups. SUMMARY OF BACKGROUND DATA:Spinopelvic alignment is subject to change in scoliosis. Many sacropelvic p...

journal_title：Spine

authors： Pasha S,Aubin CE,Sangole AP,Labelle H,Parent S,Mac-Thiong JM

更新日期：2014-04-01 00:00:00

abstract：STUDY DESIGN:A family-based study. OBJECTIVE:The aim of this study was to identify rare genetic factors predisposing to Modic changes (MCs). SUMMARY OF BACKGROUND DATA:Lumbar disc degeneration (LDD) is one of the contributing factors behind low back pain (LBP). Lumbar MC visualized as bone marrow signal intensity cha...

journal_title：Spine

authors： Kraatari M,Skarp S,Niinimäki J,Karppinen J,Männikkö M

更新日期：2017-08-15 00:00:00

abstract：:The purpose of this study was to test the validity of three clinical tests (the neck compression, the axial manual traction, and the shoulder abduction test) in the diagnosis of root compression in 43 patients with cervical disc disease. The validity was investigated regarding radicular pain, neurologic signs, and roo...

journal_title：Spine

authors： Viikari-Juntura E,Porras M,Laasonen EM

更新日期：1989-03-01 00:00:00

abstract：STUDY DESIGN:Retrospective cohort study. OBJECTIVE:To compare morbidity and mortality between nonagenarians and other older adult patients who underwent elective spine surgery. SUMMARY OF BACKGROUND DATA:There is a lack of information of the perioperative risks of nonagenarians undergoing spine surgery. METHODS:Data...

journal_title：Spine

authors： Oichi T,Oshima Y,Matsui H,Fushimi K,Tanaka S,Yasunaga H

更新日期：2019-03-01 00:00:00

abstract：STUDY DESIGN:Cross-sectional cohort study. OBJECTIVE:The aim of this study was to develop and validate a patient-completed screening questionnaire for axial spondyloarthropathy for use in the United Kingdom. SUMMARY OF BACKGROUND DATA:Axial spondyloarthropathy (axial SpA) can be difficult to diagnose in the early sta...

journal_title：Spine

authors： Hamilton L,Macgregor A,Newman D,Belkhiri A,Toms A,Gaffney K

更新日期：2013-03-15 00:00:00

abstract：STUDY DESIGN:Retrospective review. OBJECTIVE:To define the geographic variation in costs of anterior cervical discectomy and fusion (ACDF) and posterolateral fusion (PLF). SUMMARY OF BACKGROUND DATA:ACDF and lumbar PLF are common procedures that are used in the treatment of spinal pathologies. To optimize value, both...

journal_title：Spine

authors： Goz V,Rane A,Abtahi AM,Lawrence BD,Brodke DS,Spiker WR

更新日期：2015-09-01 00:00:00

abstract：STUDY DESIGN:This in vitro biomechanical study examines segmental anterior vertebral screw strain and solid rod construct stiffness with and without the addition of multilevel, threaded cortical bone dowels in a bovine model. OBJECTIVE:To determine whether strain at the bone-screw interface is higher at the end levels...

journal_title：Spine

authors： Spiegel DA,Cunningham BW,Oda I,Dormans JP,McAfee PC,Drummond DS

更新日期：2000-11-01 00:00:00

abstract：STUDY DESIGN:Characterization of the analytic profile of proteoglycans in the intervertebral discs at L4-L5 of nondiabetic (n = 5) and diabetic (n = 5) age-matched subjects. The discs used were discarded material from operations. OBJECTIVES:To clarify the reason for the higher risk of disc prolapse in diabetic patient...

journal_title：Spine

authors： Robinson D,Mirovsky Y,Halperin N,Evron Z,Nevo Z

更新日期：1998-04-15 00:00:00

abstract：STUDY DESIGN:This study investigated the effects of the intensive physical rehabilitation program on the trunk and knee extensor muscles in patients with chronic low back pain. At baseline and after 3 months, strength was measured and muscle biopsies were taken. OBJECTIVES:To evaluate the effects of strength exercises...

journal_title：Spine

authors： Rissanen A,Kalimo H,Alaranta H

更新日期：1995-02-01 00:00:00

abstract：STUDY DESIGN:In this study, data are presented that provide the surgeon with additional information about the internal structure of the thoracic pedicle, which is especially useful for pedicle screw fixation in the thoracic spine. OBJECTIVES:To quantify the internal structure of the pedicle in the thoracic spine. SUM...

journal_title：Spine

authors： Kothe R,O'Holleran JD,Liu W,Panjabi MM

更新日期：1996-02-01 00:00:00

abstract：STUDY DESIGN:Validation study to define validity and reliability of an adapted and translated questionnaire. OBJECTIVE:Assessment of the concurrent validity and reliability of a Chinese version of SRS-22 outcome instrument. SUMMARY OF BACKGROUND DATA:No valid health-related quality of life (HRQL) outcome instrument e...

journal_title：Spine

authors： Cheung KM,Senkoylu A,Alanay A,Genc Y,Lau S,Luk KD

更新日期：2007-05-01 00:00:00

abstract：STUDY DESIGN:As-treated analysis of the Spine Patient Outcomes Research Trial. OBJECTIVE:To compare baseline characteristics and surgical and nonoperative outcomes in degenerative spondylolisthesis (DS) and spinal stenosis (SpS) patients stratified by predominant pain location (i.e., leg vs. back). SUMMARY OF BACKGRO...

journal_title：Spine

authors： Pearson A,Blood E,Lurie J,Abdu W,Sengupta D,Frymoyer JW,Weinstein J

更新日期：2011-02-01 00:00:00

abstract：STUDY DESIGN:Retrospective radiographic and clinical study. OBJECTIVE:To examine the long-term outcome of selective thoracic fusion (STF) performed for lumbar "C" modifier curves in adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA:The efficacy of STF in lumbar "C" false double major curves is controversial...

journal_title：Spine

authors： Chang MS,Bridwell KH,Lenke LG,Cho W,Baldus C,Auerbach JD,Crawford CH 3rd,O'Shaughnessy BA

更新日期：2010-11-15 00:00:00

abstract：STUDY DESIGN:Systematic review, ambispective analysis of observational data. OBJECTIVE:To make recommendations as to whether or not urgent surgical decompression is ever indicated as the optimal treatment for enhancing neurologic recovery in a patient with acute central cord injury without fracture or instability. SU...

journal_title：Spine

authors： Lenehan B,Fisher CG,Vaccaro A,Fehlings M,Aarabi B,Dvorak MF

更新日期：2010-10-01 00:00:00

abstract：STUDY DESIGN:Radiology of the sacroiliac joint was investigated by obtaining different and multiple radiographs of cadaveric pelves marked with solder metal wire and radiopaque paint. OBJECTIVES:To demonstrate the orientation of the sacroiliac joint on various, radiographic views. SUMMARY OF BACKGROUND DATA:Interpret...

journal_title：Spine

authors： Ebraheim NA,Mekhail AO,Wiley WF,Jackson WT,Yeasting RA

更新日期：1997-04-15 00:00:00

abstract：STUDY DESIGN:Retrospective review of all CT scans of pelvis and abdomen performed at our institution in October and November 2000. OBJECTIVE:To determine the prevalence and extent of radiographic pelvic asymmetry in a population of patients not preselected for having low back pain. SUMMARY OF BACKGROUND DATA:Pelvic a...

journal_title：Spine

authors： Badii M,Shin S,Torreggiani WC,Jankovic B,Gustafson P,Munk PL,Esdaile JM

更新日期：2003-06-15 00:00:00

abstract：STUDY DESIGN:This longitudinal experimental study was conducted to investigate electrophysiologic characteristics, pain behavior, and histological changes in a rat model of lumbar disc herniation. OBJECTIVE:To observe abnormal spontaneous activity (ASA) on needle electromyography (EMG) and to determine its relation wi...

journal_title：Spine

authors： Kim SJ,Kim WR,Kim HS,Park HW,Cho YW,Jang SH,Hwang SJ,Ahn SH

更新日期：2011-11-15 00:00:00

abstract：STUDY DESIGN:Retrospective radiographic and chart review. OBJECTIVE:To examine the relationship between lumbar total disc replacement (TDR) range of motion (ROM) and clinical outcome at 8.6-year follow-up. SUMMARY OF BACKGROUND DATA:There are no studies on the relationship between TDR motion and clinical outcomes. M...

journal_title：Spine

authors： Huang RC,Girardi FP,Cammisa FP Jr,Lim MR,Tropiano P,Marnay T

更新日期：2005-06-15 00:00:00

abstract：STUDY DESIGN:A genetic association study. OBJECTIVE:The aim of this study was to determine whether variants of ABO, SOX6, and CDH13 are associated with the susceptibility of AIS in Chinese Han population. SUMMARY OF BACKGROUND DATA:A recent large-scale genome-wide association study reported three novel loci in CDH13,...

journal_title：Spine

authors： Wu Z,Wang Y,Dai Z,Qiu Y,Xu L,Zhu Z

更新日期：2019-09-01 00:00:00

abstract：STUDY DESIGN:A case of bilateral symptomatic facet joint synovial cysts arising in association with calcium pyrophosphate deposition disease is reported. OBJECTIVE:To present a previously unreported cause for symptomatic synovial cysts of the lumbar spine. SUMMARY OF BACKGROUND DATA:Synovial cysts of the facet joints...

journal_title：Spine

authors： Gadgil AA,Eisenstein SM,Darby A,Cassar Pullicino V

更新日期：2002-10-01 00:00:00

abstract：STUDY DESIGN:Longitudinal repeated-measures; within-subject control. OBJECTIVE:We examined the extent to which an isometric plantar flexion training protocol attenuates bone loss longitudinally after SCI. SUMMARY OF BACKGROUND DATA:After spinal cord injury (SCI), bone mineral density (BMD) of paralyzed extremities ra...

journal_title：Spine

authors： Shields RK,Dudley-Javoroski S,Law LA

更新日期：2006-03-01 00:00:00

abstract：STUDY DESIGN:Literature review. OBJECTIVE:To determine characteristics and trends in published spine research over a recent decade in a high impact, general orthopedic surgery journal. SUMMARY OF BACKGROUND DATA:Recent trends in published spine research in a high-impact orthopedic surgery journal are unknown. Such kn...

journal_title：Spine

authors： Hollenberg AM,Bernstein DN,Baldwin AL,Beltejar MJ,Rubery PT,Mesfin A

更新日期：2020-01-15 00:00:00

abstract：STUDY DESIGN:An in vitro biomechanical study of 3 lumbosacral fixation techniques in human cadaveric lumbar-pelvic spine models. OBJECTIVE:To compare the in vitro biomechanical effect of a novel 4-rod lumbosacral reconstruction technique with conventional techniques in a human cadaveric lumbopelvic model, and to evalu...

journal_title：Spine

authors： Wang T,Liu H,Zheng Z,Li Z,Wang J,Shrivastava SS,Yang H

更新日期：2013-07-01 00:00:00

abstract：STUDY DESIGN:Report of surgical technique and long-term outcome; review of prospectively gathered data and follow-up survey of patient cohort. OBJECTIVE:The aim of this study was to review surgical technique for a trephine graft harvest technique and assess perioperative complications/pain, long-term outcome, and pati...

journal_title：Spine

authors： McLain RF,Techy F

更新日期：2021-01-01 00:00:00