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Relative flexibility of DNA and RNA: a molecular dynamics study.

Abstract：

:State of the art molecular dynamics simulations are used to study the structure, dynamics, molecular interaction properties and flexibility of DNA and RNA duplexes in aqueous solution. Special attention is paid to the deformability of both types of structures, revisiting concepts on the relative flexibility of DNA and RNA duplexes. Our simulations strongly suggest that the concepts of flexibility, rigidity and deformability are much more complex than usually believed, and that it is not always true that DNA is more flexible than RNA.

journal_name

J Mol Biol

journal_title

Journal of molecular biology

authors

Noy A,Pérez A,Lankas F,Javier Luque F,Orozco M

doi

10.1016/j.jmb.2004.07.048

keywords:

subject

Has Abstract

pub_date

2004-10-22 00:00:00

pages

627-38

issue

3

eissn

0022-2836

issn

1089-8638

pii

S0022-2836(04)00877-0

journal_volume

343

pub_type

杂志文章

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