Role of connective growth factor in plasminogen activator inhibitor-1 and fibronectin expression induced by transforming growth factor beta1 in renal tubular cells.

abstract：BACKGROUND:The optimal surgical approach for four-level cervical spondylotic myelopathy remains controversial. The purpose of this study was to compare clinical and radiological outcomes and complications between the anterior and posterior approaches for four-level cervical spondylotic myelopathy. METHODS:A total of 1...

journal_title：Chinese medical journal

authors： Zhai JL,Guo SG,Nie L,Hu JH

更新日期：2020-12-05 00:00:00

abstract：OBJECTIVE:To assess the effects of Dy-DTPA-BMA (sprodiamide) on ex-vivo MR imaging of reperfused acute myocardial infarction. METHODS:Eighteen dogs were subjected to 2-hour coronary artery occlusion followed by 24-hour reperfusion. Dysprosium-chelate (Dy-DTPA-BMA) was injected into 16 dogs. Twenty minutes before their...

journal_title：Chinese medical journal

authors： Zhao S,Revel D,Arteaga C,Canet E,Liu S,Hadour G,Forrat R,Oksendal A

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Combination paclitaxel and carboplatin is currently a first-line regimen for ovarian cancer. However, many patients develop tumor recurrence or drug resistance to this regimen. The study aims to investigate the effectiveness and safety of an oxaliplatin + epirubicin + ifosfamide regimen for the treatment of ...

journal_title：Chinese medical journal

authors： Zhang G,Li XP,Liu BJ,Wang JL,Wang SJ,Cui H,Wei LH

更新日期：2013-12-01 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Lin YC,Wang YP

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:Cholesterol-lowering therapy with statins has been reported to reduce the morbidity and mortality of cardiovascular diseases. This study aimed to investigate the effects of combined application of extended-release niacin and atorvastatin on lipid profile modification and the risks of adverse events in patien...

journal_title：Chinese medical journal

authors： Sang ZC,Wang F,Zhou Q,Li YH,Li YG,Wang HP,Chen SY

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Intratracheal instillation of blood induces self-repaired acute lung injury. However, the mechanism of repair has been unclear. Heme-oxygenase (HO)-1, which catalyzes heme breakdown, acts as an inducible defense against oxidative stress and plays an important role in inflammation. The objective of this study...

journal_title：Chinese medical journal

authors： Pang QF,Zhou QM,Zeng S,Dou LD,Ji Y,Zeng YM

更新日期：2008-09-05 00:00:00

abstract：BACKGROUND:In-stent restenosis (ISR) has become one of the most challenging problems in patients with coronary heart disease. At present, using non-invasive methods to assess ISR is a hot topic. In this investigation we attempted to explore the potential of magnetocardiography (MCG) in diagnosis of in-stent restenosis....

journal_title：Chinese medical journal

authors： Quan WW,Lu GP,Qi WH,Li YM,Shen Y,Yuan R

更新日期：2008-01-05 00:00:00

abstract：BACKGROUND:While combined oral contraceptives (COCs) are commonly used to treat polycystic ovary syndrome (PCOS), comparative data regarding metabolic effects of different progestogens on this patient population are missing. This study aimed to compare the different effects of drospirenone (DRP)-containing COCs with cy...

journal_title：Chinese medical journal

authors： Wang QY,Song Y,Huang W,Xiao L,Wang QS,Feng GM

更新日期：2016-04-20 00:00:00

abstract：:In this study, we observed the endotoxin induced platelet aggregation, 5-HT and beta-g releases, cellular cAMP decrease, and also the changes of morphology and membrane fluidity of platelet. These changes play an important role in septic shock, especially in disseminated intravascular coagulation (DIC) and respiratory...

journal_title：Chinese medical journal

authors： Xu SH,Zhu GJ,Wu QX,Chen HC

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction is thought to be critical events in the pathogenesis of Alzheimer's disease (AD). Endothelial progenitor cells (EPCs) have provided insight into maintaining and repairing endothelial function. To study the relation between EPCs and AD, we explored the number of circulating EPCs in pat...

journal_title：Chinese medical journal

authors： Kong XD,Zhang Y,Liu L,Sun N,Zhang MY,Zhang JN

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To study the analgesic mechanism of gabapentin, an anticonvulsant, during antinociceptive clinical treatment. METHODS:Whole-cell voltage-clamp recordings were taken from adult rat spinal cord slices to investigate the effect of gabapentin on primary afferent A delta-fiber evoked excitatory postsynaptic curre...

journal_title：Chinese medical journal

authors： Liu Z,Xu R,Yang K

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The offspring of women with gestational diabetes mellitus (GDM) are prone to macrosomia. However, birth weight is difficult to be correctly estimated by ultrasound because of fetal asymmetric growth characteristics. This study aimed to investigate the correlations between fetal hemodynamics, fetal growth ind...

journal_title：Chinese medical journal

authors： Liu F,Liu Y,Lai YP,Gu XN,Liu DM,Yang M

更新日期：2016-09-05 00:00:00

abstract：OBJECTIVE:To rapidly and economically obtain knowledge about adult stage Schistosoma japonicum (Chinese strain) expressed genes using expressed sequence tag (EST). METHODS:A directional cDNA library constructed from Schistosoma japonicum (Chinese strain) adult stage RNA was used to generate expressed sequence tags (ES...

journal_title：Chinese medical journal

authors： Bian G,Yu X,Wu Z

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:HIV-1 infected and immune-activated macrophages and microglia secrete neurotoxins, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which play major role in the neuronal death. It has been shown that different HIV-1 variants have varying abilities to elicit secretion of TNF-α by peripheral...

journal_title：Chinese medical journal

authors： Yan YF,Wang ZY,Pu SS,Wen HL,Huang T,Song YY,Xu HZ,Zhao L

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Nontraumatic spontaneous subarachnoid hemorrhage (SAH) is associated with a high mortality. This study was conducted to investigate the epidemiological features of nontraumatic spontaneous SAH in China. METHODS:From January 2006 to December 2008, the clinical data of patients with nontraumatic SAH from 32 m...

journal_title：Chinese medical journal

authors： Song JP,Ni W,Gu YX,Zhu W,Chen L,Xu B,Leng B,Tian YL,Mao Y

更新日期：2017-04-05 00:00:00

abstract：BACKGROUND:In steroid-induced osteonecrosis, hypertrophy and hyperplasia of marrow fat cells and lipid deposition of osteocytes can be found in the femoral head. However, the precise reason is not clear yet. The aim of this study was to observe the effect of dexamethasone (Dex) on differentiation of marrow stromal cell...

journal_title：Chinese medical journal

authors： Yin L,Li YB,Wang YS

更新日期：2006-04-05 00:00:00

abstract：BACKGROUND:The aim of this research was to analyze the perioperative factors of regular hepatectomy and irregular hepatectomy. The superiority of the clinical application of the two methods was compared in the perioperative period. METHODS:From 1986 to 2011, 1798 patients underwent consecutive liver resections with re...

journal_title：Chinese medical journal

authors： Feng Z,Li H,Zhang J,Xu L,Xiao M,Huang Z,Zhang H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To study the effect for albendazole therapy for alveolar echinococcus infection in gerbils and mice. METHODS:Mice and gerbils were infected of metacestode tissues by intraperitoneal (i.p.) transplantation and treated with albendazole-medicated feeds. The effects were evaluated by comparison of the treated an...

journal_title：Chinese medical journal

authors： Liu Y,Wang X,Gao J,Yao Y,Yu D

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:With aging, the human fracture risks gradually increase. This is mainly due to the corresponding changes of the biomechanical parameters of human bone presents with aging. We measured the microstructural parameters of lumbar bone from women in several age groups by micro-computed tomography and scanning elec...

journal_title：Chinese medical journal

authors： Jiang R,Liu GM,Bai HT,Wang TB,Wu H,Jia YY,Luo YG

更新日期：2013-10-01 00:00:00

abstract：:Twin pregnancy with mosaic partial hydatidiform mole (PHM) and survival of two healthy fetuses following in vitro fertilization and embryos transfer (IVF-ET) is a rare situation and is considered a challenge for management. A 32-year-old Chinese woman conceived twin pregnancy following IVF-ET. At 22 weeks' gestation, ...

journal_title：Chinese medical journal

authors： Sun CJ,Zhao YP,Yu S,Fan L,Wu QQ,Li GH,Zhang WY

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that ultrasonography is the recommended imaging modality for preoperative staging of papillary thyroid carcinomas (PTCs). However, only a few studies have kept watch on preoperative evaluation of capsular invasion (CI) or extracapsular extension (ECE) and cervical lymph nod...

journal_title：Chinese medical journal

authors： Jiao WP,Zhang L

更新日期：2017-06-05 00:00:00

abstract：BACKGROUND:Transradial approach catheterization is now widely used in coronary angiography and angioplasty. The ulnar artery, which is one of the two terminal branches of the brachial artery, may be a potential approach for cardiac catheterization. The aim of this study was to evaluate the safety and feasibility of a t...

journal_title：Chinese medical journal

authors： Geng W,Fu X,Gu X,Jiang Y,Fan W,Wang Y,Li W,Xing K,Liu C

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Personalized medicine becomes essential in lung cancer treatment, however lung-cancer-related gene expression profiles in Chinese patients remain unknown. In this study, the correlation of gene expression profiles and clinical characteristics in non-small-cell lung cancer (NSCLC) was investigated. METHODS:S...

journal_title：Chinese medical journal

authors： Yu D,Li J,Han Y,Liu S,Xiao N,Li Y,Sun X,Liu Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The interaction between activated microglia and T lymphocytes can yield abundant pro-inflammatory cytokines. Our previous study proved that thymus immune tolerance could alleviate the inflammatory response. This study aimed to investigate whether intrathymic injection of myelin basic protein (MBP) in mice co...

journal_title：Chinese medical journal

authors： Cui ZQ,Liu BL,Wu QL,Cai Y,Fan WJ,Zhang MC,Ding WL,Zhang B,Kang JM,Yan H

更新日期：2016-04-05 00:00:00

abstract：OBJECTIVE:Dermoscopy is a useful technique for improving the diagnostic accuracy of various types of skin disorders. In China, dermoscopy has been widely accepted, and domestic researchers have made tremendous progress in the field of dermoscopy. The main purpose of this review is to summarize the current status of der...

journal_title：Chinese medical journal

authors： Shen X,Yu RX,Shen CB,Li CX,Jing Y,Zheng YJ,Wang ZY,Xue K,Xu F,Yu JB,Meng RS,Cui Y

更新日期：2019-09-05 00:00:00

abstract：OBJECTIVE:To investigate the possibility of using melanoma antigen-1 (MAGE-1) peptide as a tumor vaccine to treat hepatocellular carcinoma (HCC). METHODS:The expressions of MAGE-1 in 8 HCC cell lines and in liver cancer tissue from a patient were detected using RT-PCR. The type of human leucocyte antigen I(HLA I) of b...

journal_title：Chinese medical journal

authors： Lu J,Leng X,Peng J,Mou D,Pang X,Shang X,Chen W

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The importance of polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene for the prediction of the response to fluorouracil-based adjuvant chemotherapy in gastric cancer patients remains unclear. The aim of this study is to assess the predictive value of several polymorphisms of the MTHFR gene...

journal_title：Chinese medical journal

authors： Zhang X,Bai Z,Chen B,Feng J,Yan F,Jiang Z,Zhong Y,Wu J,Cheng L,Lu Z,Tong N,Zhang Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Prediabetes is an early stage of β-cell dysfunction presenting as insulin resistance. Evidences suggest that endoplasmic reticulum (ER) stress is involved in the pathogenesis of type 2 diabetes mellitus and prediabetes. In a Chinese population with prediabetes, we investigated single nucleotide polymorphisms...

journal_title：Chinese medical journal

authors： Feng N,Ma X,Wei X,Zhang J,Dong A,Jin M,Zhang H,Guo X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The primary ovarian sarcoma is a very rare malignancy. The objective of this study was to further investigate the clinicopathologic features and outcome in patients with primary sarcoma of the ovary. METHODS:Between 1988 and 2007, 24 patients with primary ovarian sarcoma who underwent treatment at Peking Un...

journal_title：Chinese medical journal

authors： Dai Y,Shen K,Lang JH,Huang HF,Pan LY,Wu M,Yang JX,Zhong DR

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Rituximab is used extensively in combination with chemotherapy to cure non-Hodgkin's lymphoma (NHL), and not only accelerates short-term improvement, but also prolongs patient survival and decreases receptor relapse. The aim of this study was to evaluate the impact of Fcgamma IIIA (FcgammaRIIIA) gene polymor...

journal_title：Chinese medical journal

authors： Zhang W,Wang X,Li J,Duan MH,Zhou DB

更新日期：2010-01-20 00:00:00